The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
MANKIN, H. J., DORFMAN, H., LIPPIELLO, L., & ZARINS, A. (1971) · The Journal of Bone & Joint Surgery · doi:10.2106/00004623-197153030-00009 · Cited by 1,963
Charalambous, C. P. (2014) · Classic Papers in Orthopaedics · doi:10.1007/978-1-4471-5451-8_97 · Cited by 1,835
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
Glasson, S. S., Askew, R., Sheppard, B., Carito, B., Blanchet, T., Ma, H.-L., Flannery, C. R., Peluso, D., Kanki, K., Yang, Z., et al. (2005) · Nature · doi:10.1038/nature03369 · Cited by 1,253
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
Stanton, H., Rogerson, F. M., East, C. J., Golub, S. B., Lawlor, K. E., Meeker, C. T., Little, C. B., Last, K., Farmer, P. J., Campbell, I. K., et al. (2005) · Nature · doi:10.1038/nature03417 · Cited by 915
Biochemical and Metabolic Abnormalities in Articular Cartilage from Osteo-Arthritic Human Hips
MANKIN, H. J., & LIPPIELLO, L. (1970) · The Journal of Bone & Joint Surgery · doi:10.2106/00004623-197052030-00002 · Cited by 852
Mankin, H. J., Dorfman, H., Lippiello, L., & Zarins, A. (1971) · PubMed · Cited by 796
Purification and Cloning of Aggrecanase-1: A Member of the ADAMTS Family of Proteins
Tortorella, M. D., Burn, T. C., Pratta, M. A., Abbaszade, I., Hollis, J. M., Liu, R., Rosenfeld, S. A., Copeland, R. A., Decicco, C. P., Wynn, R., et al. (1999) · Science · doi:10.1126/science.284.5420.1664 · Cited by 686
Osteoarthritis development in novel experimental mouse models induced by knee joint instability
Kamekura, S., Hoshi, K., Shimoaka, T., Chung, U., Chikuda, H., Yamada, T., Uchida, M., Ogata, N., Seichi, A., Nakamura, K., et al. (2005) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2005.03.004 · Cited by 579
The burden of musculoskeletal disease—a global perspective
Brooks, P. M. (2006) · Clinical Rheumatology · doi:10.1007/s10067-006-0240-3 · Cited by 545
Cloning and Characterization of ADAMTS11 , an Aggrecanase from the ADAMTS Family
Abbaszade, I., Liu, R.-Q., Yang, F., Rosenfeld, S. A., Ross, O. H., Link, J. R., Ellis, D. M., Tortorella, M. D., Pratta, M. A., Hollis, J. M., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23443 · Cited by 490
Cited by
Remodelling the extracellular matrix in development and disease
Bonnans, C., Chou, J., & Werb, Z. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3904 · Cited by 4,367
Osteoarthritis: A disease of the joint as an organ
Loeser, R. F., Goldring, S. R., Scanzello, C. R., & Goldring, M. B. (2012) · Arthritis & Rheumatism · doi:10.1002/art.34453 · Cited by 3,076
Role of cytokines in intervertebral disc degeneration: pain and disc content
Risbud, M. V., & Shapiro, I. M. (2014) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2013.160 · Cited by 1,767
Sarrazin, S., Lamanna, W. C., & Esko, J. D. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004952 · Cited by 1,516
Inflammation in osteoarthritis
Goldring, M. B., & Otero, M. (2011) · Current Opinion in Rheumatology · doi:10.1097/bor.0b013e328349c2b1 · Cited by 1,462
Inflammation in gout: mechanisms and therapeutic targets
So, A. K., & Martinon, F. (2017) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2017.155 · Cited by 608
Proteases involved in cartilage matrix degradation in osteoarthritis
Troeberg, L., & Nagase, H. (2012) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2011.06.020 · Cited by 579
Saito, T., Fukai, A., Mabuchi, A., Ikeda, T., Yano, F., Ohba, S., Nishida, N., Akune, T., Yoshimura, N., Nakagawa, T., et al. (2010) · Nature Medicine · doi:10.1038/nm.2146 · Cited by 532
535 East 70th Street, C. R. B., Goldring, M., Otero, M., Plumb, D., Dragomir, C., Favero, M., EI Hachem, K., Hashimoto, K., Roach, H., Olivotto, E., et al. (2011) · European Cells and Materials · doi:10.22203/ecm.v021a16 · Cited by 489
Goldring, M. B. (2012) · Therapeutic Advances in Musculoskeletal Disease · doi:10.1177/1759720x12448454 · Cited by 444
Transmembrane Signaling Proteoglycans
Couchman, J. R. (2010) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100109-104126 · Cited by 403
Homeostatic Mechanisms in Articular Cartilage and Role of Inflammation in Osteoarthritis
Houard, X., Goldring, M. B., & Berenbaum, F. (2013) · Current Rheumatology Reports · doi:10.1007/s11926-013-0375-6 · Cited by 338
Demoor, M., Ollitrault, D., Gomez-Leduc, T., Bouyoucef, M., Hervieu, M., Fabre, H., Lafont, J., Denoix, J.-M., Audigié, F., Mallein-Gerin, F., et al. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.02.030 · Cited by 296
Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway
Chang, S. H., Mori, D., Kobayashi, H., Mori, Y., Nakamoto, H., Okada, K., Taniguchi, Y., Sugita, S., Yano, F., Chung, U.-I., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09491-5 · Cited by 293
Wang, J., Markova, D., Anderson, D. G., Zheng, Z., Shapiro, I. M., & Risbud, M. V. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.264549 · Cited by 270
Proteoglycan 4 Expression Protects Against the Development of Osteoarthritis
Ruan, M. Z. C., Erez, A., Guse, K., Dawson, B., Bertin, T., Chen, Y., Jiang, M.-M., Yustein, J., Gannon, F., & Lee, B. H. L. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3005409 · Cited by 196
Chen, J., Xie, J.-J., Shi, K.-S., Gu, Y.-T., Wu, C.-C., Xuan, J., Ren, Y., Chen, L., Wu, Y.-S., Zhang, X.-L., et al. (2018) · Cell Death & Disease · doi:10.1038/s41419-017-0217-y · Cited by 130
Shifting HIFs in osteoarthritis
Husa, M., Liu-Bryan, R., & Terkeltaub, R. (2010) · Nature Medicine · doi:10.1038/nm0610-641 · Cited by 101
Syndecans in cartilage breakdown and synovial inflammation
Pap, T., & Bertrand, J. (2013) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2012.178 · Cited by 86
Self-citationVasheghani, F., Monemdjou, R., Fahmi, H., Zhang, Y., Perez, G., Blati, M., St-Arnaud, R., Pelletier, J.-P., Beier, F., Martel-Pelletier, J., et al. (2013) · The American Journal of Pathology · doi:10.1016/j.ajpath.2012.12.012 · Cited by 80
KONG, Y., WANG, W., ZHANG, C., WU, Y., LIU, Y., & ZHOU, X. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5137 · Cited by 24
Peripheral membrane associations of matrix metalloproteinases.
Van Doren, S. R., Marcink, T. C., Koppisetti, R. K., Jurkevich, A., & Fulcher, Y. G. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2017.04.013 · Cited by 22
Metadata
- Authors
- Echtermeyer, F., Bertrand, J., Dreier, R., Meinecke, I., Neugebauer, K., Fuerst, M., Lee, Y. J., Song, Y. W., Herzog, C., Theilmeier, G., & Pap, T.
- Venue
- Nature Medicine
- Published
- 2009-08-16
- Volume
- 15
- Issue
- 9
- Pages
- 1072-1076
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2007033032
- Cited by
- 318
- References
- 32
- FWCI
- 15.01
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.