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DNA released from dying host cells mediates aluminum adjuvant activity
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“A third mechanism by which alum induces Th2 responses is by causing cell death and the subsequent release of host cell DNA, which acts as a potent endogenous immunostimulatory signal [92].”
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Self-citationInnovative Vaccine Strategy: Self-Adjuvanting Conjugate Vaccines
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Metadata
- Authors
- Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. J.
- Venue
- Nature Medicine
- Published
- 2011-07-17
- Volume
- 17
- Issue
- 8
- Pages
- 996-1002
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W1968789597
- Cited by
- 535
- References
- 10
- FWCI
- 18.53
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
