Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

Min, Sang-Won, Chen, Xu, Tracy, Tara E, Li, Yaqiao, Zhou, Yungui, Wang, Chao, Shirakawa, Kotaro, Minami, S Sakura +14 more·2015·Nature Medicine
DOI 10.1038/nm.3951

Cited by (518)

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  8. The interactions of p53 with tau and Aß as potential therapeutic targets for Alzheimer’s disease
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  15. Acetylation mimic of lysine 280 exacerbates human Tau neurotoxicity in vivo
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  16. Small molecule therapeutics for tauopathy in Alzheimer’s disease: Walking on the path of most resistance
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