Cited by 810Nanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryCharacterization and Applications of Magnetic Nanoparticles

The DOI matches its Crossref record; 183 of the 183 references it cites were found in a registry or an index.

Imaging macrophages with nanoparticles

Weissleder, Ralph, Nahrendorf, Matthias, Pittet, Mikael J.·2014·Nature Materials

DOI 10.1038/nmat3780

Open this paper in CoChat — free account

Abstract

Nanomaterials have much to offer, not only in deciphering innate immune cell biology and tracking cells, but also in advancing personalized clinical care by providing diagnostic and prognostic information, quantifying treatment efficacy and designing better therapeutics. This Review presents different types of nanomaterial, their biological properties and their applications for imaging macrophages in human diseases, including cancer, atherosclerosis, myocardial infarction, aortic aneurysm, diabetes and other conditions. We anticipate that future needs will include the development of nanomaterials that are specific for immune cell subsets and can be used as imaging surrogates for nanotherapeutics. New in vivo imaging clinical tools for noninvasive macrophage quantification are thus ultimately expected to become relevant to predicting patients' clinical outcome, defining treatment options and monitoring responses to therapy.

Integrity signals

Registry

Crossref · 10.1038/nmat3780

Cites

183 of 183 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cancer-related inflammation
Mantovani, A., Allavena, P., Sica, A., & Balkwill, F. (2008) · Nature · doi:10.1038/nature07205 · Cited by 11,399
Inflammation in atherosclerosis
Libby, P. (2002) · Nature · doi:10.1038/nature01323 · Cited by 8,315
Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
Gupta, A. K., & Gupta, M. S. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.10.012 · Cited by 6,906
Macrophage plasticity and polarization: in vivo veritas
Sica, A., & Mantovani, A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci59643 · Cited by 6,335
Macrophage Diversity Enhances Tumor Progression and Metastasis
Qian, B., & Pollard, J. W. (2010) · Cell · doi:10.1016/j.cell.2010.03.014 · Cited by 5,338
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Hanahan, D., & Coussens, L. M. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.02.022 · Cited by 4,632
Alternative activation of macrophages: mechanism and functions
Gordon, S., & Martinez, F. O. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.007 · Cited by 4,197
Development of Monocytes, Macrophages, and Dendritic Cells
Geissmann, F., Manz, M. G., Jung, S., Sieweke, M. H., Merad, M., & Ley, K. (2010) · Science · doi:10.1126/science.1178331 · Cited by 3,049
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
Qian, B.-Z., Li, J., Zhang, H., Kitamura, T., Zhang, J., Campion, L. R., Kaiser, E. A., Snyder, L. A., & Pollard, J. W. (2011) · Nature · doi:10.1038/nature10138 · Cited by 2,874

Show all 183 references

Sorted by citations

Items 601–700 of 810

Nanoporous Submicron Gold Particles Enable Nanoparticle‐Based Localization Optoacoustic Tomography (nanoLOT)
Nozdriukhin, D. V., Cattaneo, M., Klingler, N., Lyu, S., Li, W., de Espinosa, F. M., Bonvin, J., Supponen, O., Razansky, D., & Deán‐Ben, X. L. (2024) · Small · doi:10.1002/smll.202404904 · Cited by 8
Dual-target nanotherapy for vascular endothelium and bone mesenchymal stem cells halt steroid-induced osteonecrosis of the femoral head progression
Yang, W., Pan, Q., Peng, Y., Hu, Y., Cui, Y., Shao, Z., Meng, C., Wang, H., & Huang, W. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.12.081 · Cited by 8
A comprehensive review on the advancement of supramolecular polymers and their pharmaceutical and biomedical applications
Singh, P., Golla, V. K., Sharma, N., & Chaudhri, N. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.217223 · Cited by 8
Nanosized Cs-pollucite zeolite synthesized under mild condition and its catalytic behavior
Aleid, G. M., Ahmad, N. H., Goldyn, K., Mintova, S., Ling, T. C., & Ng, E. (2018) · Materials Research Express · doi:10.1088/2053-1591/aaed61 · Cited by 8
Effects of nanoparticle‑mediated delivery of pitavastatin on atherosclerotic plaques in ApoE‑knockout mice and THP‑1‑derived macrophages
Sun, Y., Chen, L., Zhao, S., Shi, L., Li, H., Tian, W., & Qi, G. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.8632 · Cited by 8
Thyroid Cancers Exhibit Oncogene-Enhanced Macropinocytosis that Is Restrained by IGF1R and Promote Albumin–Drug Conjugate Response
Hu, H., Ng, T. S. C., Kang, M., Scott, E., Li, R., Quintana, J. M., Matvey, D., Vantaku, V. R., Weissleder, R., Parangi, S., et al. (2023) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-22-2976 · Cited by 8
Ultrasmall Fluorescent Silica Nanoparticles as Intraoperative Imaging Tools for Cancer Diagnosis and Treatment
Bradbury, M. S., Pauliah, M., & Wiesner, U. B. (2015) · Springer eBooks · doi:10.1007/978-1-4939-2326-7_13 · Cited by 8
Magnetite Core–Shell Nanoparticles in Nondestructive Flaw Detection of Polymeric Materials
Hetti, M., Wei, Q., Pohl, R., Casperson, R., Bartusch, M., Neu, V., Pospiech, D., & Voit, B. I. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b09934 · Cited by 8
Detection of magnetic nanoparticles with a large scale AC superconducting susceptometer
Ladino, E. A. H., Zufelato, N., Bakuzis, A. F., Carneiro, A. A. O., Covas, D. T., & Baffa, O. (2017) · Superconductor Science and Technology · doi:10.1088/1361-6668/aa7666 · Cited by 8
Developing Hollow-Channel Gold Nanoflowers as Trimodal Intracellular Nanoprobes
Ye, S., Wheeler, M., McLaughlan, J. R., Tamang, A., Diggle, C. P., Céspedes, O., MARKHAM, A. F., Coletta, P. L., & Evans, S. D. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19082327 · Cited by 8
Synthesis and in vivo evaluation of PEG-BP–BaYbF 5 nanoparticles for computed tomography imaging and their toxicity
Imberti, C., Abelha, T. F., Yan, Y., Lange, J. L., Cui, X., Szanda, I., Goh, V., Dailey, L. A., & de Rosales, R. T. M. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb00969e · Cited by 8
Third-order nonlinear optical response of ion-implanted embedded arrays of plasmonic gold nanoparticles
Zárate, J. M., Sánchez‐Dena, O., Flores-Romero, E., Peralta-Ángeles, J.-A., Reyes‐Esqueda, J. A., & Cheang-Wong, J. C. (2020) · Optical Materials · doi:10.1016/j.optmat.2020.110616 · Cited by 8
Hydrazone Molecular Switches with Paramagnetic Center as 19F Magnetic Resonance Imaging Relaxation Enhancement Agents for pH Imaging
Janasik, D., Jasiński, K., Szreder, J., Węglarz, W. P., & Krawczyk, T. (2023) · ACS Sensors · doi:10.1021/acssensors.3c00080 · Cited by 8
Application of Nanoparticles in Manufacturing
Hu, Q., Tuck, C. J., Wildman, R. D., & Hague, R. (2015) · Springer eBooks · doi:10.1007/978-3-319-13188-7_55-1 · Cited by 8
Can the biomolecular corona induce an allergic reaction?—A proof-of-concept study
Muehe, A. M., Nejadnik, H., Muehe, H., Rosenberg, J., Gharibi, H., Saei, A. A., Lyu, S., Nadeau, K. C., Mahmoudi, M., & Daldrup-Link, H. E. (2021) · Biointerphases · doi:10.1116/6.0000755 · Cited by 8
Nano-engineered solutions for extensively drug-resistant tuberculosis (XDR-TB): A novel nanomedicine
Singh, D., Krishna, V. S., Kumari, N., Banerjee, A., & Kapoor, P. (2024) · Nano-Structures & Nano-Objects · doi:10.1016/j.nanoso.2024.101390 · Cited by 8
Tumor-associated macrophage-mediated delivery of nano-photosensitizer enables light-induced metabolic programming for immuno-photodynamic therapy
Deng, H., Wang, H., Zhang, Y., Liu, R., Hou, W., Wang, L., Xu, H., & Zhang, W. (2025) · Protein & Cell · doi:10.1093/procel/pwaf064 · Cited by 7
EANM recommendations based on systematic analysis of small animal radionuclide imaging in inflammatory musculoskeletal diseases
Aarntzen, E. H. J. G., Noriega-Álvarez, E., Artiko, V. M., Dias, A. H., Gheysens, O. S., Glaudemans, A. W. J. M., Lauri, C., Treglia, G., WYNGAERT, T. V. D., van Leeuwen, F. W. B., et al. (2021) · EJNMMI Research · doi:10.1186/s13550-021-00820-8 · Cited by 7
Efficient and Stable NIR‐II Phosphorescence of Metallophilic Molecular Oligomers for In Vivo Single‐Cell Tracking and Time‐Resolved Imaging
Shi, B., Zhang, L., Yan, K., Ming, J., Chen, Z., Chen, Y., He, H., Zhang, H., Wang, L., Wang, S., et al. (2024) · Angewandte Chemie · doi:10.1002/ange.202410118 · Cited by 7
Advanced Imaging Techniques of the Skull Base
Dickerson, E. C., & Srinivasan, A. (2016) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2016.08.004 · Cited by 7
Role of nanotechnology in neurosurgery: A review of recent advances and their applications
Iqbal, J., Courville, E., Kazim, S. F., Kogan, M., Schmidt, M. H., & Bowers, C. A. (2024) · World Neurosurgery X · doi:10.1016/j.wnsx.2024.100298 · Cited by 7
Co-registered photoacoustic and fluorescent imaging of a switchable nanoprobe based on J-aggregates of indocyanine green
Dumani, D. S., Brecht, H.-P. F., Ivanov, V., Deschner, R., Harris, J. T., Homan, K. A., Cook, J. R., Emelianov, S., & Ermilov, S. A. (2018) · Photons Plus Ultrasound: Imaging and Sensing · doi:10.1117/12.2291262 · Cited by 7
Emerging use of nanoparticles in diagnosis of atherosclerosis disease: A review
Sarno, F. D., Ponsiglione, A. M., & Torino, E. (2018) · AIP conference proceedings · doi:10.1063/1.5047775 · Cited by 7
Believing in seeing
Hibbs, G. (2014) · Nature Materials · doi:10.1038/nmat3879 · Cited by 7
Matrix mechanical remodeled carrier-free nanosystem for programmable closed-loop reversal of liver fibrosis via STING alkylation
Han, H., Yu, D., Liu, Y., Jia, H., & Liu, W. (2025) · Science Advances · doi:10.1126/sciadv.adz4126 · Cited by 7
“Furthermore, macrophages exhibit a considerable capacity to recognize and eliminate larger nanoparticles, whereas their endocytic ability for smaller particles is comparatively weaker ( 32 – 34 ).”
Dynamic and Thermostable Supramolecular Hydrogels via Peptide Nanoparticle Crosslinking for Enhanced Wound Healing
Chen, H., Yin, L., Gao, Z., Gao, Y., Chen, T., Ye, H., & Wu, D. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202521667 · Cited by 6
Recent advances in assembled AIEgens for image-guided anticancer therapy
Ren, X., Zhang, S., Liu, L., Xu, B., & Tian, W. (2021) · Nanotechnology · doi:10.1088/1361-6528/ac22df · Cited by 6
Cerebral Aneurysm: Filling the Gap Between Pathophysiology and Nanocarriers
Toader, C., Rădoi, M. P., Covlea, C.-A., Covache-Busuioc, R.-A., Ilie, M.-M., Glavan, L.-A., Corlatescu, A.-D., Costin, H. P., Gica, M.-D., & Dobrin, N. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252211874 · Cited by 6
Does Encapsulation of π‐Conjugated Polymer Nanoparticles within Biodegradable PEG–PLGA Matrices Mitigate Photoinduced Free Radical Production and Phototoxicity?
Modicano, P., Trutschel, M., Phan‐Xuan, T., Matarèse, B. F. E., Urbano, L., Green, M., Mäder, K., & Dailey, L. A. (2024) · Advanced Therapeutics · doi:10.1002/adtp.202400190 · Cited by 6
Aluminium Adjuvants – A Nanomaterial used as Adjuvants in Human Vaccines for Decades
Danielsson, R., Sandberg, T., & Eriksson, H. (2018) · The Open Biotechnology Journal · doi:10.2174/1874070701812010140 · Cited by 6
Theranostic nanoplatforms for treatment and diagnosis of rectal and colon cancer: a brief review
Gholami, Y. H., & Engel, A. F. (2018) · Mini-invasive Surgery · doi:10.20517/2574-1225.2018.44 · Cited by 6
Nanoparticles and stem cells – has targeted therapy for aneurysms finally arrived?
Esfahani, D. R., Viswanathan, V. T., & Alaraj, A. M. (2014) · Neurological Research · doi:10.1179/1743132814y.0000000435 · Cited by 6
Inflammation in human cerebral aneurysms: pathogenesis, diagnostic imaging, genetics, and therapeutics
Hasan, D., Hudson, J., & Dooley, S. (2015) · Neuroimmunology and Neuroinflammation · doi:10.4103/2347-8659.154433 · Cited by 6
Size-Dependent Lymphatic Uptake of Nanoscale-Tailored Particles As Tumor Mass Increases
Kjellman, P., Fredriksson, S., Kjellman, C., Strand, S., & Zandt, R. I. ‘. (2015) · Future Science OA · doi:10.4155/fso.15.60 · Cited by 6
Glyconanotechnology and Disease: Gold Nanoparticles Coated with Glycosides as Multivalent Systems for Potential Applications in Diagnostics and Therapy
Marradi, M., Chiodo, F., & Garcı́a, I. (2015) · Royal Society of Chemistry eBooks · doi:10.1039/9781849739993-00089 · Cited by 6
Monitoring of macrophage recruitment enhanced by Toll‐like receptor 4 activation with MR imaging in nerve injury
Chen, M., Zhang, X., Lu, L., Zhang, F., Duan, X., Zheng, C., Chen, Y., & Shen, J. (2018) · Muscle & Nerve · doi:10.1002/mus.26097 · Cited by 6
Boron Compounds in Molecular Imaging
Das, B. C., Ojha, D. P., Das, S., & Evans, T. (2018) · Wiley eBooks · doi:10.1002/9781119275602.ch2.4 · Cited by 6
Magnetically switchable coordination cages: a class of supramolecular contrast agents for tumor-responsive magnetic resonance imaging
Huang, K., Li, M., Zhang, X., Linghu, X., Wang, Y., Li, W., Wu, P., Dong, J., Yang, S., & Jiao, J. (2026) · Science China Chemistry · doi:10.1007/s11426-025-3181-8 · Cited by 5
A non-lipid nucleic acid delivery vector with dendritic cell tropism and stimulation
Kim, H. S., Halabi, E. A., Enbergs, N., Köhler, R. H., Fei, F., Garris, C., & Weissleder, R. (2024) · Theranostics · doi:10.7150/thno.95267 · Cited by 5
Structural control of magnetic nanoparticles for positive nuclear magnetic resonance imaging
Ali, Z., Zhang, Y., Kaul, M. G., Truong, B., Bhanot, D., Adam, G., Li, Y., & Wei, H. (2024) · Nuclear Science and Techniques · doi:10.1007/s41365-024-01527-w · Cited by 5
Black phosphorus nanosheets in orthopedics: from material fabrications to therapeutic prospects
Sun, Y. Y., Zhang, Y., Wei, Z., Xuezhou, L., Wang, Z., Wang, K., & Kang, X. (2025) · Biomedical Materials · doi:10.1088/1748-605x/ae0548 · Cited by 5
Two-Photon Excitation-Based Imaging Postprocessing Algorithm Model for Background-Free Bioimaging
Wang, X., Yuan, W., Xu, M., & Li, F. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.0c04611 · Cited by 5
Nanotechnology-based Diagnostic Approaches for Early Detection and Monitoring of Polycystic Ovary Syndrome (PCOS)
Singh, D. (2024) · Current Analytical Chemistry · doi:10.2174/0115734110311450240612051821 · Cited by 5
Engineering cells or cellular outer membranes as multifaceted vehicles for reinforcing nanomedicine-based pulmonary disease treatment
Wang, N., Wu, J., Gao, J., & Lin, N. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102414 · Cited by 6
Uptake and Intracellular Fate of Peptide Surface-Functionalized Silica Hybrid Magnetic Nanoparticles In Vitro
Digigow, R. G., Vanhecke, D., Rothen‐Rutishauser, B., Clift, M. J. D., & Petri‐Fink, A. (2014) · Particle & Particle Systems Characterization · doi:10.1002/ppsc.201400152 · Cited by 5
Brownian particle-kinetics in a superparamagnetic ferrofluid subjected to static magnetic-field
Trisnanto, S. B., & Kitamoto, Y. (2017) · AIP conference proceedings · doi:10.1063/1.4974803 · Cited by 5
Specific Targeting of Engineered Nanoparticles to Activated Macrophages
Chuang, S.-Y., Lin, C., Aljuffali, I. A., & Fang, J. (2015) · Current Nanoscience · doi:10.2174/1573413711666150918190845 · Cited by 5
Molecular Imaging of Inflammation in Ischemic Heart Disease
Bakerman, I., Wardak, M., & Nguyen, P. K. P. (2018) · Current Cardiovascular Imaging Reports · doi:10.1007/s12410-018-9452-6 · Cited by 5
Modelling the role of flux density and coating on nanoparticle internalization by tumor cells under centrifugation
Calvo, G. F., Cortés‐Llanos, B., Belmonte-Beitia, J., Salas, G., & Ayuso‐Sacido, Á. (2019) · Applied Mathematical Modelling · doi:10.1016/j.apm.2019.10.005 · Cited by 5
Simple and Robust Intravital Microscopy Procedures in Hybrid TIE2GFP-BALB/c Transgenic Mice
Sofias, A. M., Åslund, A., Hagen, N., Grendstad, K., & Hak, S. (2019) · Molecular Imaging and Biology · doi:10.1007/s11307-019-01442-2 · Cited by 5
Application of Nanoparticles in Manufacturing
Hu, Q., Tuck, C. J., Wildman, R. D., & Hague, R. (2015) · Springer eBooks · doi:10.1007/978-3-319-15338-4_55 · Cited by 5
A Non-Peptidic S100A9 Specific Ligand for Optical Imaging of Phagocyte Activity In Vivo
Völler, T., Faust, A., Roth, J., Schäfers, M. A., Vogl, T., & Hermann, S. (2017) · Molecular Imaging and Biology · doi:10.1007/s11307-017-1148-9 · Cited by 5
Parametrizing the exposure of superparamagnetic iron oxide nanoparticles in cell cultures at different in vitro environments
Milla, M., Yu, S., & Laromaine, A. (2017) · Chemical Engineering Journal · doi:10.1016/j.cej.2017.12.070 · Cited by 5
Improving the Subcutaneous Mouse Tumor Model by Effective Manipulation of Magnetic Nanoparticles-Treated Implanted Cancer Cells
Spyridopoulou, K., Aindelis, G., Lampri, E. S., Giorgalli, M., Lamprianidou, E., Kotsianidis, Ι., Tsingotjidou, A., Pappa, A., Kalogirou, O., & Chlichlia, K. (2018) · Annals of Biomedical Engineering · doi:10.1007/s10439-018-2107-6 · Cited by 5
Meniscus Shape around Nanoparticles Embedded in Molecularly Thin Liquid Films
Eickelmann, S., Danglad‐Flores, J., Chen, G., Miettinen, M. S., & Riegler, H. E. (2018) · Langmuir · doi:10.1021/acs.langmuir.8b02266 · Cited by 5
Cubic Iron Core–Shell Nanoparticles Functionalized to Obtain High-Performance MRI Contrast Agents
Volokhova, M., Shugai, A., Tsujimoto, M., Kubo, A., Telliskivi, S., Nigul, M., Uudeküll, P., Vija, H., Bondarenko, O. M., Adamson, J., et al. (2022) · Materials · doi:10.3390/ma15062228 · Cited by 5
Imaging Tumor Metastases with Molecular Probes
Qiao, R., Zhu, R., & Gao, M. (2015) · Current Pharmaceutical Design · doi:10.2174/1381612821666151027153943 · Cited by 5
Quantitative Assessment of Binding Affinities for Nanoparticles Targeted to Vulnerable Plaque
Tang, T., Tu, C., Chow, S. Y., Leung, K. H., Du, S., & Louie, A. Y. (2015) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.5b00144 · Cited by 5
Application of Nanotechnology in Clinical Research
Sharma, M., Chauhan, P., Sharma, R., & Kumar, D. (2022) · doi:10.1002/9781119857747.ch3 · Cited by 5
Nanoparticle-based strategies for overcoming the blood-brain barrier in CNS disorders and brain cancer: precision diagnostics and therapeutics for Alzheimer’s, Parkinson’s, multiple sclerosis, and glioblastoma
Feyzbakhsh, H. (2025) · Tissue Barriers · doi:10.1080/21688370.2025.2599564 · Cited by 5
Magnetic Nanoplatelets for High Contrast Cardiovascular Imaging by Magnetically Modulated Optical Coherence Tomography
Hu, J., Goršak, T., Rodríguez, E. M., Calle, D., Muñoz‐Ortiz, T., Jaque, D., Fernández, N., Cussó, L., Rivero, F., Aguilar, R., et al. (2019) · ChemPhotoChem · doi:10.1002/cptc.201900178 · Cited by 5
A novel targeted iron oxide nanocarrier for inhibiting M2-type macrophages in the tumor microenvironment
Tian, K., Feng, R., Wang, X., Wu, X., Li, L., Liu, W., & Wu, R. (2022) · Journal of Cancer Research and Therapeutics · doi:10.4103/jcrt.jcrt_3_22 · Cited by 4
Chemokine-targeted nanoparticles: stimulation of the immune system in cancer immunotherapy
Singh, R. K., Srivastava, P., & Manna, P. P. (2023) · Exploration of Immunology · doi:10.37349/ei.2023.00093 · Cited by 4
Preparation of Bacillus-mimic liposomes destroying TAMs for the treatment of cancer
Li, Y., Yan, Z., Cong, H., Han, T., Yu, B., & Shen, Y. (2023) · Nanoscale · doi:10.1039/d3nr00656e · Cited by 4
Nanotechnology-based Assays for the Detection of Cancer through Sputum
Singh, D. (2023) · Current Analytical Chemistry · doi:10.2174/0115734110279115231102060741 · Cited by 4
Determining toxicity of europium oxide nanoparticles in immune cell components and hematopoiesis in dominant organs in mice: Role of lysosomal fluid interaction
Li, M., Gao, J., Yao, L., Zhang, L., Li, D., Li, Z., Wu, Q., Wang, S., Ding, J., Liu, Y., et al. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.173482 · Cited by 4
Increase in Dye:Dendrimer Ratio Decreases Cellular Uptake of Neutral Dendrimers in RAW Cells
Vaidyanathan, S., Kaushik, M. P., Dougherty, C. A., Rattan, R., Goonewardena, S. N., Holl, M. M. B., Monano, J., & DiMaggio, S. C. (2016) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.6b00308 · Cited by 4
Changes in the nanoparticle uptake and distribution caused by an intramacrophagic parasitic infection
Calvo, A., Moreno, E., Clemente, U., Pérez, E., Larrea, E., Sanmartín, C., Irache, J. M., & Espuelas, S. (2021) · Nanoscale · doi:10.1039/d1nr03797h · Cited by 4
Synthesis and Applications of Anisotropic Magnetic Iron Oxide Nanoparticles
Gutiérrez, L., Morales, M. P., & Roca, A. G. (2021) · Springer eBooks · doi:10.1007/978-3-030-74073-3_3 · Cited by 3
Targeted Chemotherapy Delivery via Gold Nanoparticles: A Scoping Review of In Vivo Studies
Morărașu, Ș., Iacob, Ș., Tudorancea, I., Luncă, S., & Dimofte, M. (2021) · Crystals · doi:10.3390/cryst11101169 · Cited by 4
The Magnetic Nanoparticle Actions: A Subtle Border Between Biomedicine and Toxicology
Vargas-Ortíz, J. R., González, C., & Esquivel, K. (2024) · Springer eBooks · doi:10.1007/978-981-97-0221-3_2 · Cited by 4
Characterization of Magnesium Orotate‐Loaded Chitosan Polymer Nanoparticles for a Drug Delivery System
Hassani, A., Hussain, S. A., Abdullah, N., Kamaruddin, S., & Rosli, R. (2019) · Chemical Engineering & Technology · doi:10.1002/ceat.201800478 · Cited by 4
Advances in Radiopharmaceutical Sciences for Vascular Inflammation Imaging: Focus on Clinical Applications
Prigent, K., & Vigne, J. (2021) · Molecules · doi:10.3390/molecules26237111 · Cited by 4
Mcl-1 small-molecule inhibitors encapsulated into nanoparticles exhibit increased killing efficacy towards HCMV-infected monocytes
Burrer, C. M., Auburn, H., Wang, X., Luo, J., Abulwerdi, F. A., Nikolovska‐Coleska, Z., & Chan, G. C. T. (2016) · Antiviral Research · doi:10.1016/j.antiviral.2016.11.027 · Cited by 4
Macrophage‐Anchored Nanofibers with Supramolecular Phenolic Gates for pH‐Responsive Chemotherapy
Yu, R., Guo, T., Zhu, Z., Shi, J. M., Lin, S., Lan, J., & Shang, J. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202504208 · Cited by 3
Low‐Power‐Activated Afterglow Nanoprobes With Naked‐Eye Visibility for High‐Contrast Imaging of Brain Inflammation
Ouyang, J., Li, Y., Chen, R., Su, X., & Liu, Z. (2026) · Angewandte Chemie International Edition · doi:10.1002/anie.3145716 · Cited by 3
Rational Design of Self‐Assembling Artificial Proteins Utilizing a Micelle‐Assisted Protein Labeling Technology (MAPLabTech): Testing the Scope**
Reddy, M. M., Bhandari, P. J., Hati, K. C., & Sandanaraj, B. S. (2022) · ChemBioChem · doi:10.1002/cbic.202100607 · Cited by 3
Potential Resistance to Antineoplastic Aminated Fullerenes Mediated by M2-Like Monocyte-Derived Exosomes
Huo, J., Zhou, W., Liu, Y., Yang, S., Li, J., & Wang, C. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.779939 · Cited by 3
Impact of administration route on nanocarrier biodistribution in a murine colitis model
Applegate, C. C., Deng, H., Kleszynski, B. L., Cross, T.-W., Konopka, C. J., Dobrucki, L. W., Nelson, E. R., Wallig, M. A., Smith, A. M., & Swanson, K. S. (2022) · Journal of Experimental Nanoscience · doi:10.1080/17458080.2022.2134563 · Cited by 3
Immunogenic antitumor potential of Prakasine nanoparticles in zebrafish by gene expression stimulation
Prakash, S. K. (2023) · Artificial Cells Nanomedicine and Biotechnology · doi:10.1080/21691401.2023.2173217 · Cited by 3
Simulations and Experimental Study of Individual Au Nanoparticle Using Photothermal Heterodyne Imaging (PHI)
Wang, Y., Wang, F., Liu, J., Chen, M., & Wang, Y. (2021) · IEEE Transactions on Instrumentation and Measurement · doi:10.1109/tim.2021.3138090 · Cited by 3
Macrophages mediated biomimetic drug delivery systems
Sun, X., Zhu, D., & Cai, Y. (2018) · Journal of Nanomedicine · doi:10.33582/2578-8760/1003 · Cited by 3
Molecular Imaging of Macrophages in Atherosclerosis
Koga, J., & Aikawa, M. (2014) · Springer eBooks · doi:10.1007/978-3-319-09268-3_3 · Cited by 3
ROS-mediated Cytotoxicity and Macrophage Activation Induced by TiO2 Nanoparticles with Different in vitro Non-Cellular Photocatalytic Activities
Popescu, T., Cremer, L., Tudor, M., & Lupu, A. (2016) · South East European Journal of Immunology · doi:10.3889/seejim.2016.20007 · Cited by 3
Medical Applications of Nanomaterials
Vedda, A., & Villa, I. (2017) · NATO science for peace and security series. B, Physics and biophysics · doi:10.1007/978-94-024-0850-8_18 · Cited by 3
Highly reliable benzothiophene-phenylquinoline based heteroleptic Ir(III) complexes; The solution process NIR phosphorescence organic light-emitting diodes
Cho, W., Kim, H., Gal, Y., & Jin, S. (2017) · Molecular Crystals and Liquid Crystals · doi:10.1080/15421406.2017.1355692 · Cited by 3
Magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds?
Herrmann, I. K., Schlegel, A. A., Graf, R., Stark, W. J., & Beck‐Schimmer, B. (2016) · nano Online · doi:10.1515/nano.12951_2015.9 · Cited by 3
Therapeutic Use of Inorganic Nanomaterials in Malignant Diseases
Lupu, A., Popescu, T., & Stojanović, M. (2019) · Environmental chemistry for a sustainable world · doi:10.1007/978-3-030-26672-1_2 · Cited by 2
Engineered Hybrid Nanoparticles for Multimodal Medical Imaging and Diagnosis
Shetty, A., & Chandra, S. (2022) · Springer eBooks · doi:10.1007/978-3-031-09636-5_12 · Cited by 2
Identity crisis of nanostructures inside the human body: a perspective on inflammation
Saha, S., & Saso, L. (2023) · Frontiers in Nanotechnology · doi:10.3389/fnano.2023.1256952 · Cited by 3
Design of a Novel Drug Delivery Nanosystem that Simultaneously Realizes Real‐Time Tracing and Drug Delivery Across the Blood–Brain Barrier
Wang, X., Qin, L., Song, B., Wu, M., & Liang, W. (2023) · Advanced Materials Interfaces · doi:10.1002/admi.202300738 · Cited by 2
Innovations in skin cancer treatment: The role of nanotechnology and cellular biotechnology
Mamadapur, S. A., Jadhav, H. Y., Lodh, M., & Kale, P. P. (2025) · Journal of Cellular Biotechnology · doi:10.1177/23523689241311783 · Cited by 2
Imbalance of phosphoric acid homeostasis in alveolar macrophages mediates lung toxicity of rare earth oxide nanoparticles
Li, H., Zhang, J., Han, Z., Zhang, W., Song, D., Zhang, L., Zheng, Y., Tang, J., & Tian, S. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.118265 · Cited by 2
Development of biocompatible nanocubes as a T 1 -contrast enhancer for MR imaging of primary and metastatic liver cancer
Song, X., Xu, X., Wan, H., & Tang, Q. (2014) · RSC Advances · doi:10.1039/c4ra09554e · Cited by 2
Smart Theranostic Nano Materials: Recent Progress from Bench to Bedside Translation
Bhattarai, S. R. (2015) · Journal of Nanomedicine Research · doi:10.15406/jnmr.2015.02.00041 · Cited by 2
MRI Investigation of New Approach to Improve the Recovery of Myocardial Ischemia Reperfusion Injury by Treatment with Intralipid®
Wu, Y. L., Liu, L., Yeh, F.-C. F., Rosario, B. L., & Ho, C. (2016) · World Journal of Cardiovascular Diseases · doi:10.4236/wjcd.2016.610041 · Cited by 2
In-vivo Visualization of Iron Oxide Enhancement in Focal Pulmonary Inflammatory Lesions Using a Three-Dimensional Radial Gradient-Echo-Based Ultrashort Echo Time Sequence: A Preliminary Study
Yoon, S. H., Lee, C., Park, J., Goo, J. M., & Park, J. (2018) · Korean Journal of Radiology · doi:10.3348/kjr.2018.19.1.153 · Cited by 2
Biomaterials for Engineering Immune Responses
Jhunjhunwala, S. (2018) · Journal of the Indian Institute of Science · doi:10.1007/s41745-018-0063-7 · Cited by 2
Nanosized magnetic particles for cancer theranostics
Hameed, S., & Bhattarai, P. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816897-4.00009-6 · Cited by 2
Plant and human health
Panzarini, E., Carata, E., Mariano, S., Tenuzzo, B. A., Tacconi, S., Fidaleo, M., & Dini, L. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-823394-8.00007-x · Cited by 2

Authors: Weissleder, R., Nahrendorf, M., & Pittet, M. J.
Affiliations: Harvard University (US)
Massachusetts General Hospital (US)
Corresponding author: Weissleder, Ralph
ORCID: Weissleder, Ralph
Nahrendorf, Matthias
Venue: Nature Materials
Publisher: Springer Science and Business Media LLC
Published: 2014-01-23
Volume: 13
Issue: 2
Pages: 125-138
ISSN: 1476-1122 (ISSN-L)
1476-4660
DOI: 10.1038/nmat3780
OpenAlex: W2092877053
Cited by: 809
References: 183
Citations by year: 2026: 25 · 2025: 31 · 2024: 36 · 2023: 51 · 2022: 61 · 2021: 67 · 2020: 80 · 2019: 64 · 2018: 90 · 2017: 105 · 2016: 90 · 2015: 79 · 2014: 28
FWCI: 8.63
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
www.springer.com/tdm (vor)
Locations: Nature Materials (publishedVersion)
PubMed (publishedVersion)
Archive ouverte UNIGE (University of Geneva) (publishedVersion)
Archive ouverte UNIGE (University of Geneva) (submittedVersion)
Topics: Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Physical Sciences › Engineering › Biomedical Engineering › Characterization and Applications of Magnetic Nanoparticles
Keywords: macrophages, nanomaterials, macrophage targeting, tumor imaging, atherosclerosis, myocardial infarction, aortic aneurysm, diabetes mellitus, inflammation, innate immunity, cell tracking, non-invasive imaging, nanotherapeutics
MeSH terms: Humans, Inflammation, Macrophages, Nanoparticles, Cell Tracking

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Imaging macrophages with nanoparticles

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks