Chemically defined generation of human cardiomyocytes

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Items 101–200 of 1,002

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3. Cardiac Regeneration
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4. Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts
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5. Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium
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7. Stem cells as therapy for heart disease: iPSCs, ESCs, CSCs, and skeletal myoblasts
   Reza Rikhtegar, Masoud Pezeshkian, Sanam Dolati, Naser Safaie, Abbas Afrasiabi Rad, Mahdi Mahdipour, Mohammad Nouri, Ahmadreza Jodati, Mehdi Yousefi · 2018 · Biomedicine & Pharmacotherapy
8. A Universal and Robust Integrated Platform for the Scalable Production of Human Cardiomyocytes From Pluripotent Stem Cells
   Hananeh Fonoudi, Hassan Ansari, Saeed Abbasalizadeh, Mehran Rezaei Larijani, Sahar Kiani, Shiva Hashemizadeh, Ali Sharifi‐Zarchi, Alexis Bosman, Gillian M. Blue, Sara Pahlavan et al. · 2015 · Stem Cells Translational Medicine
9. Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue
   Vahid Serpooshan, Pu Chen, Haodi Wu, Soah Lee, Arun Sharma, Daniel A. Hu, Sneha Venkatraman, Adarsh Ganesan, Osman Berk Usta, Martin L. Yarmush et al. · 2017 · Biomaterials
10. Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models
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11. Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis
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12. Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?
    Luca Sala, Milena Bellin, Christine L. Mummery · 2016 · British Journal of Pharmacology
13. Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction
    Rui Guo, Masatoshi Morimatsu, Feng Tian, Feng Lan, Dehua Chang, Feng Wan, Yunpeng Ling · 2020 · Stem Cell Research & Therapy
14. Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes as Models for Cardiac Channelopathies
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15. SarcTrack
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16. Targeting CaMKII-δ9 Ameliorates Cardiac Ischemia/Reperfusion Injury by Inhibiting Myocardial Inflammation
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17. Distinctive Roles of Canonical and Noncanonical Wnt Signaling in Human Embryonic Cardiomyocyte Development
    Silvia Mazzotta, Carlos Neves, Rory J. Bonner, Andreia Sofia Bernardo, Kevin Docherty, Stefan Hoppler · 2016 · Stem Cell Reports
18. Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function
    Alexa N. Wnorowski, Arun Sharma, Haodong Chen, Haodi Wu, Ning‐Yi Shao, Nazish Sayed, Chun Liu, Stefanie M. Countryman, Louis Stodieck, Kathleen Rubins et al. · 2019 · Stem Cell Reports
19. Embryos and embryonic stem cells from the white rhinoceros
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20. Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes
    David A. Knowles, Courtney K. Burrows, John Blischak, Kristen M Patterson, Daniel Serie, Nadine Norton, Carole Ober, Jonathan K. Pritchard, Yoav Gilad · 2018 · eLife
21. Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety
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22. TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes
    Jason Wayne Miklas, Elisa C. Clark, Shiri Levy, Damien Detraux, Andrea Leonard, Kevin M. Beussman, Megan Reed Showalter, Alec S.T. Smith, Peter Hofsteen, Xiulan Yang et al. · 2019 · Nature Communications
23. Congenital heart disease risk loci identified by genome-wide association study in European patients
    Harald Lahm, Meiwen Jia, Martina Dreßen, Felix Wirth, Nazan Puluca, Ralf Gilsbach, Bernard D. Keavney, Julie Cleuziou, Nicole Beck, Olga Bondareva et al. · 2020 · Journal of Clinical Investigation
24. Animal-derived products in science and current alternatives
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25. Generation, functional analysis and applications of isogenic three-dimensional self-aggregating cardiac microtissues from human pluripotent stem cells
    Giulia Campostrini, Viviana Meraviglia, Elisa Giacomelli, Ruben W.J. van Helden, Loukia Yiangou, Richard P. Davis, Milena Bellin, Valeria V. Orlova, Christine L. Mummery · 2021 · Nature Protocols
26. Derivation of Highly Purified Cardiomyocytes from Human Induced Pluripotent Stem Cells Using Small Molecule-modulated Differentiation and Subsequent Glucose Starvation
    Arun Sharma, Guang Li, Kuppusamy Rajarajan, Ryoko Hamaguchi, Paul W. Burridge, Sean M. Wu · 2015 · Journal of Visualized Experiments
27. Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload
    Zhen Ma, Nathaniel Huebsch, Sang-Mo Koo, Mohammad A. Mandegar, Brian A. Siemons, Steven C. Boggess, Bruce R. Conklin, Costas P. Grigoropoulos, Kevin E. Healy · 2018 · Nature Biomedical Engineering
28. Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems
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29. Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease
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30. Large-scale production of human pluripotent stem cell derived cardiomyocytes
    Henning Kempf, Birgit Andrée, Robert Zweigerdt · 2015 · Advanced Drug Delivery Reviews
31. Current methods for the maturation of induced pluripotent stem cell-derived cardiomyocytes
    Machiraju, Pranav, Greenway, Steven C · 2019 · World Journal of Stem Cells
32. Novel CaMKII-δ Inhibitor Hesperadin Exerts Dual Functions to Ameliorate Cardiac Ischemia/Reperfusion Injury and Inhibit Tumor Growth
    Junxia Zhang, Ruqi Liang, Kai Wang, Wenjia Zhang, Mao Zhang, Li Jin, Peng Xie, Wen Zheng, Haibao Shang, Qingmei Hu et al. · 2022 · Circulation
33. Human induced pluripotent stem cells as a platform for personalized and precision cardiovascular medicine
    Matsa, Elena, Ahrens, John H., Wu, Joseph C. · 2016 · Physiological Reviews
34. A cost-effective and efficient reprogramming platform for large-scale production of integration-free human induced pluripotent stem cells in chemically defined culture
    Jeanette K. Beers, Kaari L. Linask, Jane A. Chen, Lauren I. Siniscalchi, Yongshun Lin, Wei Zheng, Mahendra S. Rao, Guokai Chen · 2015 · Scientific Reports
35. Effect of Cell Sex on Uptake of Nanoparticles: The Overlooked Factor at the Nanobio Interface
    Vahid Serpooshan, Sara Sheibani, Pooja Pushparaj, Michal Wojcik, Albert Youngwoo Jang, Michelle Rai Santoso, Joyce H. Jang, Haina Huang, Reihaneh Safavi‐Sohi, Niloofar Haghjoo et al. · 2018 · ACS Nano
36. Differentiation of Cardiomyocytes from Human Pluripotent Stem Cells Using Monolayer Culture
    Ivan Batalov, Adam W. Feinberg · 2015 · Biomarker Insights
37. The Future of Regenerative Medicine: Cell Therapy Using Pluripotent Stem Cells and Acellular Therapies Based on Extracellular Vesicles
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38. Functional correction of dystrophin actin binding domain mutations by genome editing
    Viktoriia Kyrychenko, Sergii Kyrychenko, Malte Tiburcy, John Michael Shelton, Chengzu Long, Jay W. Schneider, Wolfram‐Hubertus Zimmermann, Rhonda Bassel‐Duby, Eric N. Olson · 2017 · JCI Insight
39. Formative pluripotent stem cells show features of epiblast cells poised for gastrulation
    Xiaoxiao Wang, Yunlong Xiang, Yang Yu, Ran Wang, Yu Zhang, Qianhua Xu, Hao Sun, Zhen‐Ao Zhao, Xiangxiang Jiang, Xiaoqing Wang et al. · 2021 · Cell Research
40. Simulated Microgravity and 3D Culture Enhance Induction, Viability, Proliferation and Differentiation of Cardiac Progenitors from Human Pluripotent Stem Cells
    Rajneesh Jha, Qingling Wu, Monalisa Singh, Marcela K. Preininger, Pengcheng Han, Gouliang Ding, Hee Cheol Cho, Hanjoong Jo, Kevin O'D. Maher, Mary B. Wagner et al. · 2016 · Scientific Reports
41. MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
    Lorna R. Fiedler, Kathryn Chapman, Min Xie, Evie Maifoshie, Micaela Jenkins, Pelin Arabacilar Golforoush, Mohamed Bellahcene, Michela Noseda, Dörte Faust, Ashley Jarvis et al. · 2019 · Cell stem cell
42. Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells
    Francesca Stillitano, Jens Hansen, Chi‐Wing Kong, Ioannis Karakikes, Christian Funck‐Brentano, Lin Geng, Stuart Alexander Scott, Stephan Reynier, Wu Ma, Yannick Valogne et al. · 2017 · eLife
43. Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture
    Caroline Halloin, Kristin Schwanke, Wiebke Löbel, Annika Franke, Mónika Szepes, Santoshi Biswanath, Stephanie Wunderlich, Sylvia Merkert, Natalie Weber, Felix Osten et al. · 2019 · Stem Cell Reports
44. Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture
    Ergir, Ece, Oliver-De La Cruz, Jorge, Fernandes, Soraia, Cassani, Marco, Niro, Francesco, Pereira-Sousa, Daniel, Vrbský, Jan, Vinarský, Vladimír, Perestrelo, Ana Rubina, Debellis, Doriana et al. · 2022 · Scientific Reports
45. Wnt Signaling in Heart Development and Regeneration
    Dongliang Li, Jianjian Sun, Tao P. Zhong · 2022 · Current Cardiology Reports
46. Efficient and reproducible generation of human iPSC-derived cardiomyocytes and cardiac organoids in stirred suspension systems
    Maksymilian Prondzynski, Paul Berkson, Michael A. Trembley, Yashasvi Tharani, Kevin Shani, Raul Hernandes Bortolin, Mason Sweat, Joshua Mayourian, Doğacan Yücel, Albert M. Cordoves et al. · 2024 · Nature Communications
47. Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes
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48. Cell alignment induced by anisotropic electrospun fibrous scaffolds alone has limited effect on cardiomyocyte maturation
    Jingjia Han, Qingling Wu, Younan Xia A, Mary B. Wagner, Chunhui Xu · 2016 · Stem Cell Research
49. Long noncoding RNA Meg3 regulates cardiomyocyte apoptosis in myocardial infarction
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50. Direct Cardiac Reprogramming
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51. Identification of Drug Transporter Genomic Variants and Inhibitors That Protect Against Doxorubicin-Induced Cardiotoxicity
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52. Graphene biointerfaces for optical stimulation of cells
    A. K. Savchenko, Volodymyr Cherkas, Chao Liu, Gary B. Braun, Alexander M. Kleschevnikov, Yury I. Miller, Elena Molokanova · 2018 · Science Advances
53. Cellular and Engineered Organoids for Cardiovascular Models
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54. Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization
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55. Induced Pluripotent Stem Cell Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity
    Silin Sa, Mingxia Gu, James Chappell, Ning‐Yi Shao, Mohamed Ameen, Kathryn Elliott, Dan Li, Fabian Grubert, Caiyun Grace Li, Shalina Taylor et al. · 2016 · American Journal of Respiratory and Critical Care Medicine
56. Electrical Stimulation Enhances Cardiac Differentiation of Human Induced Pluripotent Stem Cells for Myocardial Infarction Therapy
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57. Native cardiac environment and its impact on engineering cardiac tissue
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58. Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies
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59. Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells
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60. Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness
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61. Modeling Reentry in the Short QT Syndrome With Human-Induced Pluripotent Stem Cell–Derived Cardiac Cell Sheets
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62. Modeling Cardiovascular Diseases with hiPSC-Derived Cardiomyocytes in 2D and 3D Cultures
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63. Transplantation of human induced pluripotent stem cell-derived cardiomyocytes improves myocardial function and reverses ventricular remodeling in infarcted rat hearts
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64. Direct hydrogel encapsulation of pluripotent stem cells enables ontomimetic differentiation and growth of engineered human heart tissues
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65. Pluripotent Stem Cell-Derived Cardiomyocytes as a Platform for Cell Therapy Applications: Progress and Hurdles for Clinical Translation
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66. Genetic Variation in Enhancers Modifies Cardiomyopathy Gene Expression and Progression
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67. Patient‐Specific Organoid and Organ‐on‐a‐Chip: 3D Cell‐Culture Meets 3D Printing and Numerical Simulation
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68. Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells
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69. Modeling Cardiac Disease Mechanisms Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Progress, Promises and Challenges
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70. Modeling structural and functional deficiencies ofRBM20familial dilated cardiomyopathy using human induced pluripotent stem cells
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71. Allele-specific ablation rescues electrophysiological abnormalities in a human iPS cell model of long-QT syndrome with a CALM2 mutation
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72. Genetics of Anthracycline Cardiomyopathy in Cancer Survivors
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73. Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease
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74. The Roles of Neuregulin-1 in Cardiac Development, Homeostasis, and Disease
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75. Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances
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76. Universal Cardiac Induction of Human Pluripotent Stem Cells in Two and Three-Dimensional Formats: Implications for In Vitro Maturation
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77. HDAC inhibitor valproic acid protects heart function through Foxm1 pathway after acute myocardial infarction
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78. Nanofibrous clinical-grade collagen scaffolds seeded with human cardiomyocytes induces cardiac remodeling in dilated cardiomyopathy
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79. Suppression-Replacement KCNQ1 Gene Therapy for Type 1 Long QT Syndrome
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80. Identification of novel biomarkers for doxorubicin-induced toxicity in human cardiomyocytes derived from pluripotent stem cells
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81. Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract
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82. Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research
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83. Engineered Microenvironments for Maturation of Stem Cell Derived Cardiac Myocytes
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84. Big bottlenecks in cardiovascular tissue engineering
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85. Gene expression profiling of hypertrophic cardiomyocytes identifies new players in pathological remodelling
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86. Modulation of human mesenchymal and pluripotent stem cell behavior using biophysical and biochemical cues: A review
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87. Interfacing Cells with Vertical Nanoscale Devices: Applications and Characterization
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88. Laminin-511 and laminin-521-based matrices for efficient hepatic specification of human pluripotent stem cells
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89. Non-invasive electromechanical cell-based biosensors for improved investigation of 3D cardiac models
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90. Human-induced pluripotent stem cells in cardiovascular research: current approaches in cardiac differentiation, maturation strategies, and scalable production
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91. Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes
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92. Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species
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93. Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes
    Mandy Kleinsorge, Lukas Cyganek · 2020 · STAR Protocols
94. Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome
    Lau, Edward, Han, Yu, Williams, Damon R., Thomas, Cody T., Shrestha, Rajani, Wu, Joseph C., Lam, Maggie P.Y. · 2019 · Cell Reports
95. Biodegradable Nanofibrous Temperature‐Responsive Gelling Microspheres for Heart Regeneration
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96. Single-cell sequencing reveals lineage-specific dynamic genetic regulation of gene expression during human cardiomyocyte differentiation
    Reem Elorbany, Joshua M Popp, Katherine Rhodes, Benjamin J. Strober, Kenneth Barr, Guanghao Qi, Yoav Gilad, Alexis J. Battle · 2022 · PLoS Genetics
97. In Vitro Models of Ischemia-Reperfusion Injury
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98. Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variations
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99. RARG variant predictive of doxorubicin-induced cardiotoxicity identifies a cardioprotective therapy
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100. Mechanical stimulation in the engineering of heart muscle
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