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Cited by 485

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Interhemispheric correlations of slow spontaneous neuronal fluctuations revealed in human sensory cortex

Open access
Nir, Yuval, Mukamel, Roy, Dinstein, Ilan, Privman, Eran, Harel, Michal, Fisch, Lior, Gelbard-Sagiv, Hagar, Kipervasser, Svetlana, Andelman, Fani, Neufeld, Miri Y, Kramer, Uri, Arieli, Amos, Fried, Itzhak, Malach, Rafael·2008·Nature Neuroscience
DOI 10.1038/nn.2177
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Abstract

Animal studies have shown robust electrophysiological activity in the sensory cortex in the absence of stimuli or tasks. Similarly, recent human functional magnetic resonance imaging (fMRI) revealed widespread, spontaneously emerging cortical fluctuations. However, it is unknown what neuronal dynamics underlie this spontaneous activity in the human brain. Here we studied this issue by combining bilateral single-unit, local field potentials (LFPs) and intracranial electrocorticography (ECoG) recordings in individuals undergoing clinical monitoring. We found slow (<0.1 Hz, following 1/f-like profiles) spontaneous fluctuations of neuronal activity with significant interhemispheric correlations. These fluctuations were evident mainly in neuronal firing rates and in gamma (40–100 Hz) LFP power modulations. Notably, the interhemispheric correlations were enhanced during rapid eye movement and stage 2 sleep. Multiple intracranial ECoG recordings revealed clear selectivity for functional networks in the spontaneous gamma LFP power modulations. Our results point to slow spontaneous modulations in firing rate and gamma LFP as the likely correlates of spontaneous fMRI fluctuations in the human sensory cortex.

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Research works printed but not linked: 35

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Metadata

Authors
Nir, Y., Mukamel, R., Dinstein, I., Privman, E., Harel, M., Fisch, L., Gelbard-Sagiv, H., Kipervasser, S., Andelman, F., Neufeld, M. Y., Kramer, U., Arieli, A., Fried, I., & Malach, R.
Venue
Nature Neuroscience
Publisher
Springer Science and Business Media LLC
Published
2008-08-24
Volume
11
Issue
9
Pages
1100-1108
ISSN
  • 1097-6256 (ISSN-L)
  • 1546-1726
DOI
10.1038/nn.2177
OpenAlex
W2109569847
Cited by
485
References
15
FWCI
16.07
Type
journal article
Language
en
Open access
green
Licence
www.springer.com/tdm (tdm)

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Nir, Y., Mukamel, R., Dinstein, I., Privman, E., Harel, M., Fisch, L., Gelbard-Sagiv, H., Kipervasser, S., Andelman, F., Neufeld, M. Y., Kramer, U., Arieli, A., Fried, I., & Malach, R. (2008). Interhemispheric correlations of slow spontaneous neuronal fluctuations revealed in human sensory cortex. Nature Neuroscience. https://doi.org/10.1038/nn.2177

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