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Cited by 306

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin

Open access
Bossert, Jennifer M, Stern, Anna L, Theberge, Florence R M, Cifani, Carlo, Koya, Eisuke, Hope, Bruce T, Shaham, Yavin·2011·Nature Neuroscience

Abstract

In a rat model of context-induced relapse to heroin, we identified sparsely distributed ventral medial prefrontal cortex (mPFC) neurons that were activated by the heroin-associated context. Selective pharmacogenetic inactivation of these neurons inhibited context-induced drug relapse. A small subset of ventral mPFC neurons formed neuronal ensembles that encode the learned associations between heroin reward and heroin-associated contexts; re-activation of these neuronal ensembles by drug-associated contexts during abstinence provoked drug relapse.

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Crossref · 10.1038/nn.2758

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Metadata

Authors
Bossert, J. M., Stern, A. L., Theberge, F. R. M., Cifani, C., Koya, E., Hope, B. T., & Shaham, Y.
Venue
Nature Neuroscience
Published
2011-02-20
Volume
14
Issue
4
Pages
420-422
ISSN
  • 1097-6256 (ISSN-L)
  • 1546-1726
OpenAlex
W2026145070
Cited by
306
References
4
FWCI
8.10
Type
journal article
Language
en
Open access
green

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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