The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Vertical nanowire electrode arrays as a scalable platform for intracellular interfacing to neuronal circuits
Open accessAbstract
Deciphering the neuronal code - the rules by which neuronal circuits store and process information - is a major scientific challenge1,2. Currently, these efforts are impeded by a lack of experimental tools that are sensitive enough to quantify the strength of individual synaptic connections and also scalable enough to simultaneously measure and control a large number of mammalian neurons with single-cell resolution3,4. Here, we report a scalable intracellular electrode platform based on vertical nanowires that affords parallel electrical interfacing to multiple mammalian neurons. Specifically, we show that our vertical nanowire electrode arrays (VNEAs) can intracellularly record and stimulate neuronal activity in dissociated cultures of rat cortical neurons and can also be used to map multiple individual synaptic connections. The scalability of this platform, combined with its compatibility with silicon nanofabrication techniques, provides a clear path toward simultaneous, high-fidelity interfacing with hundreds of individual neurons.
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Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics
Kim, D.-H., Viventi, J., Amsden, J. J., Xiao, J., Vigeland, L., Kim, Y.-S., Blanco, J. A., Panilaitis, B., Frechette, E. S., Contreras, D., et al. (2010) · Nature Materials · doi:10.1038/nmat2745 · Cited by 1,721
Network anatomy and in vivo physiology of visual cortical neurons
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Three-Dimensional, Flexible Nanoscale Field-Effect Transistors as Localized Bioprobes
Tian, B., Cohen-Karni, T., Qing, Q., Duan, X., Xie, P., & Lieber, C. M. (2010) · Science · doi:10.1126/science.1192033 · Cited by 798
HEK293 cell line: A vehicle for the expression of recombinant proteins
Thomas, P., & Smart, T. G. (2005) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/j.vascn.2004.08.014 · Cited by 771
Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures
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Spike Timing-Dependent Plasticity: From Synapse to Perception
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Brain–machine interfaces to restore motor function and probe neural circuits
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Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells
Shalek, A. K., Robinson, J. T., Karp, E. S., Lee, J. S., Ahn, D.-R., Yoon, M.-H., Sutton, A., Jorgolli, M., Gertner, R. S., Gujral, T. S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909350107 · Cited by 569
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A Review of Organic and Inorganic Biomaterials for Neural Interfaces
Fattahi, P., Yang, G., Kim, G., & Abidian, M. R. (2014) · Advanced Materials · doi:10.1002/adma.201304496 · Cited by 580
Next-generation probes, particles, and proteins for neural interfacing
Rivnay, J., Wang, H., Fenno, L., Deisseroth, K., & Malliaras, G. G. (2017) · Science Advances · doi:10.1126/sciadv.1601649 · Cited by 514
Metadata
- Authors
- Robinson, J. T., Jorgolli, M., Shalek, A. K., Yoon, M.-H., Gertner, R. S., & Park, H.
- Venue
- Nature Nanotechnology
- Published
- 2012-01-10
- Volume
- 7
- Issue
- 3
- Pages
- 180-184
- ISSN
- 1748-3387 (ISSN-L)
- 1748-3395
- OpenAlex
- W2117155287
- Cited by
- 600
- References
- 31
- FWCI
- 20.90
- Type
- journal article
- Language
- en
- Open access
- green
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- Robinson, J. T., Jorgolli, M., Shalek, A. K., Yoon, M.-H., Gertner, R. S., & Park, H. (2012). Vertical nanowire electrode arrays as a scalable platform for intracellular interfacing to neuronal circuits. Nature Nanotechnology. https://doi.org/10.1038/nnano.2011.249
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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