DNA-encoded chemistry: enabling the deeper sampling of chemical space

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Items 101–200 of 644

1. High-power screening (HPS) empowered by DNA-encoded libraries
   Yashoda Krishna Sunkari, Vijay Kumar Siripuram, Thu-Lan Nguyen, Marc Flajolet · 2021 · Trends in Pharmacological Sciences
2. Self-assembly strategies of organic small-molecule photosensitizers for photodynamic therapy
   Xiaohui Xiong, Jingyuan Liu, Lei Wu, Shuangyu Xiong, Wen Jiang, Peng Wang · 2024 · Coordination Chemistry Reviews
3. Lung Cancer Heterogeneity and New Strategies for Drug Therapy
   Diane C. Wang, William Yang Wang, Bijun Zhu, Xiangdong Wang · 2017 · The Annual Review of Pharmacology and Toxicology
4. DNA-Compatible [3 + 2] Nitrone–Olefin Cycloaddition Suitable for DEL Syntheses
   Christopher J. Gerry, Zhenhua Yang, Michele Stasi, Stuart L. Schreiber · 2019 · Organic Letters
5. Photocatalytic [2 + 2] Cycloaddition in DNA-Encoded Chemistry
   Dominik K. Kölmel, Anokha S. Ratnayake, Mark E. Flanagan, Mei‐Hsuan Tsai, Cong Duan, Chao Song · 2020 · Organic Letters
6. Affinity Enhancement of Protein Ligands by Reversible Covalent Modification of Neighboring Lysine Residues
   Alberto Dal Corso, Marco Catalano, Anja Sophie Schmid, Jörg Scheuermann, Dario Neri · 2018 · Angewandte Chemie International Edition
7. Development of a small molecule that corrects misfolding and increases secretion of Z α1‐antitrypsin
   David A. Lomas, James A. Irving, Christopher C. Arico-Muendel, Svetlana L. Belyanskaya, A.S. Brewster, Murray J. B. Brown, Chun‐wa Chung, Hitesh Dave, Alexis Denis, Nérina Dodic et al. · 2021 · EMBO Molecular Medicine
8. Photoredox-mediated hydroalkylation and hydroarylation of functionalized olefins for DNA-encoded library synthesis
   Shorouk O. Badir, Alexander Lipp, Matthias Krumb, María Jesús Cabrera‐Afonso, Lisa Marie Kammer, Victoria E. Wu, Minxue Huang, Adam Csakai, Lisa A. Marcaurelle, Gary Alan Molander · 2021 · Chemical Science
9. DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M pro inhibitors
   Srinivas Chamakuri, Shuo Lu, Melek Nihan Ucisik, Kurt M. Bohren, Ying‐Chu Chen, Huang-Chi Du, John C. Faver, Ravikumar Jimmidi, Feng Li, Jianyuan Li et al. · 2021 · Proceedings of the National Academy of Sciences
10. Emerging drug development technologies targeting ubiquitination for cancer therapeutics
    Gianluca Veggiani, María Carla Rosales Gerpe, Sachdev S. Sidhu, Wei Zhang · 2019 · Pharmacology & Therapeutics
11. Using Physicochemical Measurements to Influence Better Compound Design
    Shenaz B. Bunally, Christopher N. Luscombe, Robert J. Young · 2019 · SLAS DISCOVERY
12. Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing
    David Kodr, Cansu Pinar Yenice, Anna Šimonová, Dijana Saftić, Radek Pohl, Veronika Sýkorová, Mayreli Ortiz, Luděk Havran, Miroslav Fojta, Zbigniew Jan Lesnikowski et al. · 2021 · Journal of the American Chemical Society
13. The era of high-quality chemical probes
    Marco P. Licciardello, Paul Workman · 2022 · RSC Medicinal Chemistry
14. Nucleic Acid Templated Reactions for Chemical Biology
    Margherita Di Pisa, Oliver Seitz · 2017 · ChemMedChem
15. Non-transition Metal-Mediated Diverse Aryl–Heteroatom Bond Formation of Arylammonium Salts
    Dong‐Yu Wang, Xin Wen, Chaodong Xiong, Jiannan Zhao, Chunyong Ding, Meng Qian, Hu Zhou, Chao Wang, Masanobu Uchiyama, Xiaojie Lu et al. · 2019 · iScience
16. DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor
    Raphael I. Benhamou, Blessy M. Suresh, Yuquan Tong, Wesley G. Cochrane, Valerie J. Cavett, Simon Vézina‐Dawod, Daniel Abegg, Jessica L. Childs‐Disney, Alexander Adibekian, Brian M. Paegel et al. · 2022 · Proceedings of the National Academy of Sciences
17. Streamlined construction of peptide macrocycles via palladium-catalyzed intramolecular S -arylation in solution and on DNA
    Peng Yang, Xuan Wang, Bo Li, Yixuan Yang, Jinfeng Yue, Yanrui Suo, Huarong Tong, Gang He, Xiaojie Lu, Gong Chen · 2021 · Chemical Science
18. High-Throughput Screening
    Mary Jo Wildey, Anders Haunsø, Matthew Tudor, Maria L. Webb, Jonathan H. Connick · 2017 · Annual reports in medicinal chemistry
19. Acoustic Droplet Ejection Enabled Automated Reaction Scouting
    Yuanze Wang, Shabnam Shaabani, Maryam Ahmadianmoghaddam, Li Ting Gao, Ruixue Xu, Katarzyna Kurpiewska, Justyna Kalinowska‐Tłuścik, Joe Olechno, Richard N. Ellson, Michael Kossenjans et al. · 2019 · ACS Central Science
20. An Amphiphilic Polymer-Supported Strategy Enables Chemical Transformations under Anhydrous Conditions for DNA-Encoded Library Synthesis
    Yves Ruff, Roberto Martinez, Xavier Pellé, Pierre Nimsgern, Pascale Fille, Maxim O. Ratnikov, Frédéric Berst · 2020 · ACS Combinatorial Science
21. Palladium-Promoted DNA-Compatible Heck Reaction
    Xuan Wang, Hui Sun, Jiaxiang Liu, Wenge Zhong, Mingqiang Zhang, Hu Zhou, Dongcheng Dai, Xiaojie Lu · 2019 · Organic Letters
22. Navigating the DNA encoded libraries chemical space
    A. Velasco Martín, Christos A. Nicolaou, Miguel Ángel Toledo · 2020 · Communications Chemistry
23. Can easy chemistry produce complex, diverse, and novel molecules?
    Anna Tomberg, Jonas Boström · 2020 · Drug Discovery Today
24. High Fidelity Suzuki–Miyaura Coupling for the Synthesis of DNA Encoded Libraries Enabled by Micelle Forming Surfactants
    James H. Hunter, Lisa Prendergast, Louis F. Valente, Andrew Madin, Garry Pairaudeau, Michael J. Waring · 2019 · Bioconjugate Chemistry
25. Mild and Efficient Palladium-Mediated C–N Cross-Coupling Reaction between DNA-Conjugated Aryl Bromides and Aromatic Amines
    Eduardo de Pedro Beato, Julián Priego, Adrián Gironda-Martínez, Fernando González‐Pérez, Jesús Benavides, Jesús de Blas, María Dolores Martín-Ortega, Miguel Ángel Toledo, Jesús Ezquerra, Alicia Torrado · 2019 · ACS Combinatorial Science
26. Molecular design opportunities presented by solvent‐exposed regions of target proteins
    Xiangyi Jiang, Ji Hoon Yu, Zhongxia Zhou, Jacob Kongsted, Yuning Song, Christophe C. Pannecouque, Erik De Clercq, Dongwei Kang, Vasanthanathan Poongavanam, Xinyong Liu et al. · 2019 · Medicinal Research Reviews
27. Radical C–H Sulfonation of Arenes: Its Applications on Bioactive and DNA-Encoded Molecules
    Yue Zhang, Shengdi Xia, Wenxia Shi, Bizhen Lin, Xiao‐can Su, Weiwei Lu, Xinyuan Wu, Xuan Wang, Xiaojie Lu, Ming Yan et al. · 2022 · Organic Letters
28. Cheminformatics in Drug Discovery, an Industrial Perspective
    Hongming Chen, Thierry Kogej, Ola Engkvist · 2018 · Molecular Informatics
29. Development of DNA-Compatible Van Leusen Three-Component Imidazole Synthesis
    Stefanie N. Geigle, Ann C. Petersen, Alexander Lee Satz · 2019 · Organic Letters
30. C–N Coupling of DNA-Conjugated (Hetero)aryl Bromides and Chlorides for DNA-Encoded Chemical Library Synthesis
    Ying‐Chu Chen, John C. Faver, Angela F. Ku, Gabriella Miklóssy, Kevin P. Riehle, Kurt M. Bohren, Melek Nihan Ucisik, Martin Matthew Matzuk, Zhifeng Yu, Nicholas Simmons · 2020 · Bioconjugate Chemistry
31. Drug design targeting active posttranslational modification protein isoforms
    Fanwang Meng, Zhongjie T. Liang, Kehao Zhao, Cheng Luo · 2020 · Medicinal Research Reviews
32. Efficient copper-catalyzed amination of DNA-conjugated aryl iodides under mild aqueous conditions
    Yves Ruff, Frédéric Berst · 2018 · MedChemComm
33. Ideal‐Filter Capillary Electrophoresis (IFCE) Facilitates the One‐Step Selection of Aptamers
    An T. H. Le, Svetlana M. Krylova, Mirzo Kanoatov, Shrey P. Desai, Sergey N. Krylov · 2018 · Angewandte Chemie International Edition
34. DNA‐Encoded Libraries: Towards Harnessing their Full Power with Darwinian Evolution
    Millicent Dockerill, Nicolas Winssinger · 2022 · Angewandte Chemie International Edition
35. Gem -Difluorocyclopropenes as Versatile β-Monofluorinated Three-sp 2 Carbon Sources for Cp*Rh(III)-Catalyzed [4 + 3] Annulation: Experimental Development and Mechanistic Insight
    Huiying Xu, Weijie Chen, Mengyao Bian, Hongtao Xu, Hui Gao, Ting Wang, Zhi Zhou, Wei Yi · 2021 · ACS Catalysis
36. Therapeutic strategies of targeting non-apoptotic regulated cell death (RCD) with small-molecule compounds in cancer
    Xin Jin, Wenke Jin, Linlin Tong, Jia Zhao, Lan Zhang, Na Lin · 2024 · Acta Pharmaceutica Sinica B
37. Robustness of In Vitro Selection Assays of DNA-Encoded Peptidomimetic Ligands to CBX7 and CBX8
    Kyle E. Denton, Sijie Wang, Michael C. Gignac, Natalia Milosevich, Fraser A. Hof, Emily C. Dykhuizen, Casey J. Krusemark · 2018 · SLAS DISCOVERY
38. On-DNA Hydroalkylation to Introduce Diverse Bicyclo[1.1.1]pentanes and Abundant Alkyls via Halogen Atom Transfer
    Expédite Yen‐Pon, Longbo Li, Guillaume Levitre, Jadab Majhi, Edward J. McClain, Eric A. Voight, Erika A. Crane, Gary Alan Molander · 2022 · Journal of the American Chemical Society
39. A DNA‐Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition
    Nicholas Favalli, Stefan Biendl, Marco Hartmann, Jacopo Piazzi, Filippo Sladojevich, S. Gräslund, Peter J. Brown, Katja Näreoja, Herwig Schuler, Jörg Scheuermann et al. · 2018 · ChemMedChem
40. Photoredox cross-electrophile coupling in DNA-encoded chemistry
    Dominik K. Kölmel, Anokha S. Ratnayake, Mark E. Flanagan · 2020 · Biochemical and Biophysical Research Communications
41. Machine Learning on DNA-Encoded Library Count Data Using an Uncertainty-Aware Probabilistic Loss Function
    Katherine S. Lim, Andrew G. Reidenbach, Bruce K. Hua, Jeremy W. Mason, Christopher J. Gerry, Paul A. Clemons, Connor W. Coley · 2022 · Journal of Chemical Information and Modeling
42. Unexpected Cyclization Product Discovery from the Photoinduced Bioconjugation Chemistry between Tetrazole and Amine
    Juan Zhang, Jinlu Liu, Xianfeng Li, Yunzhu Ju, Yangfeng Li, Gong Zhang, Yizhou Li · 2024 · Journal of the American Chemical Society
43. Screening of metal ions and organocatalysts on solid support-coupled DNA oligonucleotides guides design of DNA-encoded reactions
    Marco Potowski, Florian Losch, Elena Wünnemann, Janina K. Dahmen, Silvia Chines, Andreas Brunschweiger · 2019 · Chemical Science
44. Selection of Small Molecules that Bind to and Activate the Insulin Receptor from a DNA-Encoded Library of Natural Products
    Jia Xie, Shuyue Wang, Peixiang Ma, Fei Ma, Jie Li, Wei Wang, Fengping Lu, Huan Xiong, Yuang Gu, Shuning Zhang et al. · 2020 · iScience
45. Affinity Capillary Electrophoresis: A Critical Review of the Literature from 2018 to 2020
    Yao Wang, Damilola I. Adeoye, Emmanuel O. Ogunkunle, I-An Wei, Robert T. Filla, Michael G. Roper · 2020 · Analytical Chemistry
46. A DNA‐Encoded Chemical Library Based on Peptide Macrocycles
    Yuichi Onda, Gabriele Bassi, Abdullah Elsayed, Franziska Ulrich, Sebastian Oehler, Louise Plais, Jörg Scheuermann, Dario Neri · 2021 · Chemistry - A European Journal
47. Streamlining bioactive molecular discovery through integration and automation
    Shiao Y. Chow, Samuel Liver, Adam S. Nelson · 2018 · Nature Reviews Chemistry
48. Abiotic peptides as carriers of information for the encoding of small-molecule library synthesis
    Simon L. Rössler, Nathalie M. Grob, Stephen L. Buchwald, Bradley L. Pentelute · 2023 · Science
49. Degraders upgraded: the rise of PROTACs in hematological malignancies
    Joshua M. L. Casan, John Francis Seymour · 2024 · Blood
50. Acid- and Au( i )-mediated synthesis of hexathymidine-DNA-heterocycle chimeras, an efficient entry to DNA-encoded libraries inspired by drug structures
    Mateja Klika Škopić, Hazem Salamon, Olivia Bugain, Kathrin Jung, Anne Gohla, Lara Dötsch, Denise dos Santos, Avinash S. Bhat, Bernd Wagner, Andreas Brunschweiger · 2017 · Chemical Science
51. Second generation DNA-encoded dynamic combinatorial chemical libraries
    Francesco V. Reddavide, Meiying Cui, Weilin Lin, Naiqiang Fu, Stephan Heiden, Helena Andrade, Michael Thompson, Yixin Zhang · 2019 · Chemical Communications
52. A Single‐Stranded DNA‐Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks
    Gabriele Bassi, Nicholas Favalli, Miriam Vuk, Marco Catalano, Adriano Luca Martinelli, Anika Trenner, Antônio Porro, Su Yang, Chuin Lean Tham, Mustafa Moroglu et al. · 2020 · Advanced Science
53. Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry
    Guilinger, John P., Archna, Archna, Augustin, Martin, Bergmann, Andreas, Centrella, Paolo A., Clark, Matthew A., Cuozzo, John W., Däther, Maike, Guié, Marie-Aude, Habeshian, Sevan et al. · 2021 · Bioorganic & Medicinal Chemistry
54. Quantitative Assessment of Affinity Selection Performance by Using DNA‐Encoded Chemical Libraries
    Alessandro Sannino, Elena Gabriele, Martina Bigatti, Sara Mulatto, Jacopo Piazzi, Jörg Scheuermann, Dario Neri, Etienne J. Donckèle, Florent Samain · 2018 · ChemBioChem
55. Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries
    Doris Mia Taylor, Justin L. Anglin, Suhyeorn Park, Melek Nihan Ucisik, John C. Faver, Nicholas Simmons, Zhuang Jin, Murugesan Palaniappan, Pranavanand Nyshadham, Feng Li et al. · 2020 · ACS Infectious Diseases
56. Bioinspired Selenium‐Nitrogen Exchange (SeNEx) Click Chemistry Suitable for Nanomole‐Scale Medicinal Chemistry and Bioconjugation
    Wei Hou, Yiyuan Zhang, Fuchao Huang, Wanting Chen, Yuang Gu, Yan Wang, Jiacheng Pang, Hewei Dong, Kangyin Pan, Shuning Zhang et al. · 2024 · Angewandte Chemie International Edition
57. DNA-Encoded Combinatorial Library of Macrocyclic Peptoids
    Min Hyeon Shin, KangJu Lee, Hyun‐Suk Lim · 2019 · Bioconjugate Chemistry
58. A mating mechanism to generate diversity for the Darwinian selection of DNA-encoded synthetic molecules
    Balayeshwanth R. Vummidi, Lluc Farrera Soler, Jean‐Pierre Daguer, Millicent Dockerill, Sofía Barluenga, Nicolas Winssinger · 2021 · Nature Chemistry
59. Metal-free deoxygenative coupling of alcohol-derived benzoates and pyridines for small molecules and DNA-encoded libraries synthesis
    Sai Rohini Narayanan Kolusu, Manuel Nappi · 2022 · Chemical Science
60. Organo-Se BTSAs-enabled performance: From racemic and asymmetric synthesis to click chemistry application
    Zhi Zhou, Yuang Gu, Liexin Wu, Yan Wang, Huiying Xu, Lei Ma, Zhaoyong Zhang, Jincun Zhao, Wei Zhang, Wei Peng et al. · 2023 · Chem
61. Inverse-Electron-Demand Diels–Alder Reactions for the Synthesis of Pyridazines on DNA
    Hailong Li, Zhen Cui Sun, Wenting Wu, Xuan Wang, Mingqiang Zhang, Xiaojie Lu, Wenge Zhong, Dongcheng Dai · 2018 · Organic Letters
62. Reversible Covalent Headpiece Enables Interconversion between Double‐ and Single‐Stranded DNA‐Encoded Chemical Libraries
    Guixian Zhao, Shuting Zhong, Gong Zhang, Yangfeng Li, Yizhou Li · 2021 · Angewandte Chemie International Edition
63. Carbohydrate–DNA Conjugation Enabled by Glycosyl Radicals Generated from Glycosyl Sulfinates
    Hongxin Zeng, Yanjing Li, Rongfeng Wu, Daqi Liu, Yang Zhang, Shiyang Xu, Dawen Niu · 2023 · Organic Letters
64. Targeting epigenetic machinery: Emerging novel allosteric inhibitors
    Fei Ye, Jing Li Huang, Hongbo Wang, Cheng Luo, Kehao Zhao · 2019 · Pharmacology & Therapeutics
65. DNA-Compatible Diazo-Transfer Reaction in Aqueous Media Suitable for DNA-Encoded Chemical Library Synthesis
    Adrián Gironda-Martínez, Dario Neri, Florent Samain, Etienne J. Donckèle · 2019 · Organic Letters
66. Functionalization of DNA-Tagged Alkenes with Diazo Compounds via Photocatalysis
    Xiang Fu, Jie Tang, Ruyu Hua, Xiaoqian Li, Zhenghui Kang, Huang Qiu, Wenhao Hu · 2022 · Organic Letters
67. New Modalities, Technologies, and Partnerships in Probe and Lead Generation: Enabling a Mode-of-Action Centric Paradigm
    Eric Valeur, Patrick Jimonet · 2018 · Journal of Medicinal Chemistry
68. Synthesis of DNA-coupled isoquinolones and pyrrolidines by solid phase ytterbium- and silver-mediated imine chemistry
    Marco Potowski, Verena B. K. Kunig, Florian Losch, Andreas Brunschweiger · 2019 · MedChemComm
69. Supramolecular Nanodrugs Constructed by Self-Assembly of Peptide Nucleic Acid–Photosensitizer Conjugates for Photodynamic Therapy
    Rui Chang, Emmanouil Nikoloudakis, Qianli Zou, Anna Mitraki, Athanassios Georgios Coutsolelos, Xuehai Yan · 2019 · ACS Applied Bio Materials
70. Chemically Programmable and Switchable CAR‐T Therapy
    Junpeng Qi, Kohei Tsuji, David Hymel, Terrence R. Burke, Michael Hudecek, Christoph M. Rader, Haiyong Peng · 2020 · Angewandte Chemie International Edition
71. Synthetic Studies toward DNA-Encoded Heterocycles Based on the On-DNA Formation of α,β-Unsaturated Ketones
    Sixiu Liu, Jingjing Qi, Weiwei Lu, Xuan Wang, Xiaojie Lu · 2021 · Organic Letters
72. Targeting key proteins involved in transcriptional regulation for cancer therapy: Current strategies and future prospective
    Haixiang Pei, Weikai Guo, Yangrui Peng, Hai Xiong, Yihua Chen · 2022 · Medicinal Research Reviews
73. Highly pure DNA-encoded chemical libraries by dual-linker solid-phase synthesis
    Michelle Keller, Dimitar D. Petrov, Andreas Gloger, Bastien Dietschi, Kilian Jobin, T.B. Gradinger, Adriano Luca Martinelli, Louise Plais, Yuichi Onda, Dario Neri et al. · 2024 · Science
74. All-fiber all-optical quantitative polymerase chain reaction (qPCR)
    Xuegang Li, Linh Viet Nguyen, Kelly Hill, Heike Ebendorff‐Heidepriem, Erik P. Schartner, Yong Zhao, Xue Zhou, Yanan Zhang, Stephen Christopher Warren-Smith · 2020 · Sensors and Actuators B Chemical
75. Developments in Photoredox-Mediated Alkylation for DNA-Encoded Libraries
    Shivani Patel, Shorouk O. Badir, Gary Alan Molander · 2020 · Trends in Chemistry
76. Preparation of Structurally Diverse Compounds from the Natural Product Lycorine
    Sarah Z. Tasker, Amanda E. Cowfer, Paul J. Hergenrother · 2018 · Organic Letters
77. Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries
    Olivier B. C. Monty, Pranavanand Nyshadham, Kurt M. Bohren, Murugesan Palaniappan, Martin Matthew Matzuk, Damian W. Young, Nicholas Simmons · 2020 · ACS Combinatorial Science
78. Triaging of DNA-Encoded Library Selection Results by High-Throughput Resynthesis of DNA–Conjugate and Affinity Selection Mass Spectrometry
    Wenji Su, Rui Ge, Duanchen Ding, Wen‐Hua Chen, Wenqing Wang, Hao Yan, Weikun Wang, Youlang Yuan, Huan Liu, Meng Zhang et al. · 2021 · Bioconjugate Chemistry
79. Discovery of SARS-CoV-2 main protease covalent inhibitors from a DNA-encoded library selection
    Rui Ge, Zuyuan Shen, Jian Yin, Wen‐Hua Chen, Qi Zhang, Yulong An, Dewei Tang, Alexander Lee Satz, Wenji Su, Letian Kuai · 2022 · SLAS DISCOVERY
80. A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition
    Sebastian Oehler, Laura Lucaroni, Francesca Migliorini, Abdullah Elsayed, Luca Prati, Sara Puglioli, Mattia Matasci, Kristina Schira, Jörg Scheuermann, Denis Yudin et al. · 2023 · Nature Chemistry
81. Idea2Data: Toward a New Paradigm for Drug Discovery
    Christos A. Nicolaou, Christine C. Humblet, Hong Hu, Eva María Domínguez-Martín, Frank Charles Dorsey, Thomas M. Castle, Keith I. Burton, Haitao Hu, Jörg Hendle, Michael J. Hickey et al. · 2019 · ACS Medicinal Chemistry Letters
82. Synthesis of Multifunctional 2-Aminobenzimidazoles on DNA via Iodine-Promoted Cyclization
    Liqiang Su, Jing Feng, Ting Peng, Jinqiao Wan, Jing Fan, Jin Li, Jonathan C. O’Connell, David R. Lancia, G. Joseph Franklin, Guansai Liu · 2020 · Organic Letters
83. Augmenting Hit Identification by Virtual Screening Techniques in Small Molecule Drug Discovery
    Xin Cindy Yan, John M. Sanders, Ying-Duo Gao, Matthew Tudor, Andrew M. Haidle, Daniel J. Klein, Antonella Converso, Charles A. Lesburg, Yi Zang, Harold B. Wood · 2020 · Journal of Chemical Information and Modeling
84. Synthesis of 1,2-Amino Alcohols by Photoredox-Mediated Decarboxylative Coupling of α-Amino Acids and DNA-Conjugated Carbonyls
    Huanan Wen, Rui Ge, Yi Qu, Jialin Sun, Xiaodong Shi, Weiren Cui, Hao Yan, Qi Zhang, Yulong An, Wenji Su et al. · 2020 · Organic Letters
85. Sequential DNA-Encoded Building Block Fusion for the Construction of Polysubstituted Pyrazoline Core Libraries
    Juan Zhang, Xianfeng Li, Haimei Wei, Yangfeng Li, Gong Zhang, Yizhou Li · 2021 · Organic Letters
86. In-solution direct oxidative coupling for the integration of sulfur/selenium into DNA-encoded chemical libraries
    Shilian Yang, Guixian Zhao, Yuting Gao, Sun Yang, Gong Zhang, Xiaohong Fan, Yangfeng Li, Yizhou Li · 2022 · Chemical Science
87. Rethinking therapeutic strategies of dual‐target drugs: An update on pharmacological small‐molecule compounds in cancer
    Yang Yi-ren, Yi Mou, Lin‐Xi Wan, Shiou Zhu, Guan Wang, Huiyuan Gao, Bo Liu · 2024 · Medicinal Research Reviews
88. Selecting a DNA-Encoded Chemical Library against Non-immobilized Proteins Using a “Ligate–Cross-Link–Purify” Strategy
    Bingbing Shi, Yuqing Deng, Peng Zhao, Xiaoyu Li · 2017 · Bioconjugate Chemistry
89. DNA-Compatible Nitro Reduction and Synthesis of Benzimidazoles
    Huang-Chi Du, Hongbing Huang · 2017 · Bioconjugate Chemistry
90. Docking domain-mediated subunit interactions in natural product megasynth(et)ases
    Helen G. Smith, Matthew J. Beech, Józef Romuald Lewandowski, Gregory L. Challis, Matthew Jenner · 2021 · Journal of Industrial Microbiology & Biotechnology
91. DNA-Encoded Library Hit Confirmation: Bridging the Gap Between On-DNA and Off-DNA Chemistry
    Bing Xia, G. Joseph Franklin, Xiaojie Lu, Katie L. Bedard, LaShadric C. Grady, Jennifer D. Summerfield, Eric Shi, Bryan W. King, Kenneth E. Lind, Cynthia H. Chiu et al. · 2021 · ACS Medicinal Chemistry Letters
92. Metal-Catalyzed One-Pot On-DNA Syntheses of Diarylmethane and Thioether Derivatives
    Fei Ma, Jie Li, Shuning Zhang, Yuang Gu, Tingting Tan, Wanting Chen, Shuyue Wang, Hongtao Xu, Guang Yang, Richard Alan Lerner · 2022 · ACS Catalysis
93. Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor
    Lu, Yan, Qin, Shanshan, Zhang, Bingjie, Dai, Antao, Cai, Xiaoqing, Ma, Mengna, Gao, Zhan-Guo, Yang, Dehua, Stevens, Raymond C., Jacobson, Kenneth A. et al. · 2019 · Analytical Chemistry
94. The most common linkers in bioactive molecules and their bioisosteric replacement network
    Peter Ertl, Eva Altmann, Sophie Racine · 2023 · Bioorganic & Medicinal Chemistry
95. Reversible male contraception by targeted inhibition of serine/threonine kinase 33
    Angela F. Ku, Kiran Lata Sharma, Hai Minh Ta, Courtney M. Sutton, Kurt M. Bohren, Yong Wang, Srinivas Chamakuri, Ruihong Chen, John M. Hakenjos, Ravikumar Jimmidi et al. · 2024 · Science
96. Designing DNA Encoded Libraries of Diverse Products in a Focused Property Space
    Hongyao Zhu, Mark E. Flanagan, Robert V. Stanton · 2019 · Journal of Chemical Information and Modeling
97. Off-DNA DNA-Encoded Library Affinity Screening
    Amber L. Hackler, Forrest G. FitzGerald, Vuong Q. Dang, Alexander Lee Satz, Brian M. Paegel · 2019 · ACS Combinatorial Science
98. Diversified strategy for the synthesis of DNA-encoded oxindole libraries
    Xuan Wang, Jiaxiang Liu, Ziqin Yan, Xiaohong Liu, Sixiu Liu, Yanrui Suo, Weiwei Lu, Jinfeng Yue, Kaixian Chen, Hualiang Jiang et al. · 2021 · Chemical Science
99. Highly efficient on-DNA amide couplings promoted by micelle forming surfactants for the synthesis of DNA encoded libraries
    James H. Hunter, Matthew J. Anderson, Isaline F. S. F. Castan, Jessica S. Graham, Catherine L. A. Salvini, Harriet A. Stanway‐Gordon, James J. Crawford, Andrew Madin, Garry Pairaudeau, Michael J. Waring · 2021 · Chemical Science
100. Forty years of combinatorial technology
     Árpád Furka · 2022 · Drug Discovery Today