DNA-encoded chemistry: enabling the deeper sampling of chemical space

Cited by (644)

Items 301–400 of 644

1. Modular Approaches to Synthesize Activity- and Affinity-Based Chemical Probes
   Antonie J. van der Zouwen, Martin D. Witte · 2021 · Frontiers in Chemistry
2. Second-generation DNA-encoded multiple display on a constant macrocyclic scaffold enabled by an orthogonal protecting group strategy
   Qigui Nie, Shuting Zhong, Yangfeng Li, Gong Zhang, Yizhou Li · 2021 · Chinese Chemical Letters
3. Converting Double-Stranded DNA-Encoded Libraries (DELs) to Single-Stranded Libraries for More Versatile Selections
   Yuhan Gui, Clara Shania Wong, Guixian Zhao, Chao Xie, Rui Hou, Yizhou Li, Gang Li, Xiaoyu Li · 2022 · ACS Omega
4. Two-Phase Flow in a Coiled Flow Inverter: Process Development from Batch to Continuous Flow
   Jens Bobers, Julia Grühn, Stefan Höving, Tobias Pyka, Norbert Kockmann · 2020 · Organic Process Research & Development
5. Virtual fragment screening for DNA repair inhibitors in vast chemical space
   Andreas Luttens, Duc Duy Vo, Emma Rose Scaletti, Elisée Wiita, Ingrid Almlöf, Olov A. Wallner, Jonathan R. Davies, Sara Persson Košenina, Liuzhen Meng, Maeve Long et al. · 2025 · Nature Communications
6. Design and synthesis of a DNA-encoded combinatorial library of bicyclic peptoids
   KangJu Lee, Geul Bang, Yong Wook Kim, Min Hyeon Shin, Hyun‐Suk Lim · 2021 · Bioorganic & Medicinal Chemistry
7. Generation of Glycosyl Radicals from Glycosyl Sulfoxides and Its Use in the Synthesis of C ‐linked Glycoconjugates
   Weidong Shang, Shengnan Su, Rong Shi, Ze‐Dong Mou, YU Guo-qiang, Xia Zhang, Dawen Niu · 2020 · Angewandte Chemie
8. Trio-pharmacophore DNA-encoded chemical library for simultaneous selection of fragments and linkers
   Meiying Cui, D. Nguyen, Michelle Patino Gaillez, Stephan Heiden, Weilin Lin, Michael Thompson, Francesco V. Reddavide, Qinchang Chen, Yixin Zhang · 2023 · Nature Communications
9. Application of a Substrate-Mediated Selection with c-Src Tyrosine Kinase to a DNA-Encoded Chemical Library
   Dongwook Kim, Yixing Sun, Dan Xie, Kyle E. Denton, Hao Chen, Hang Lin, Michael K. Wendt, Carol Beth Post, Casey J. Krusemark · 2019 · Molecules
10. A patent review of discoidin domain receptor 1 (DDR1) modulators (2014-present)
    Jing Guo, Zhen Zhang, Ke Ding · 2020 · Expert Opinion on Therapeutic Patents
11. PNA-Based Dynamic Combinatorial Libraries (PDCL) and screening of lectins
    Lluc Farrera Soler, Jean‐Pierre Daguer, Patrick Raunft, Sofía Barluenga, Anne Imberty, Nicolas Winssinger · 2020 · Bioorganic & Medicinal Chemistry
12. Targeting in silico GPCR conformations with ultra-large library screening for hit discovery
    Davide Sala, Hossein Batebi, Kaitlyn V. Ledwitch, Peter Werner Hildebrand, Jens Meiler · 2023 · Trends in Pharmacological Sciences
13. Split & mix assembly of DNA libraries for ultrahigh throughput on-bead screening of functional proteins
    Laurens H. Lindenburg, Tuomas Huovinen, Kayleigh M. van de Wiel, Michael Herger, Michael R. Snaith, Florian Hollfelder · 2020 · Nucleic Acids Research
14. Synthesis of 5-substituted tetrazoles via DNA-conjugated nitrile
    Huang-Chi Du, Martin Matthew Matzuk, Ying‐Chu Chen · 2020 · Organic & Biomolecular Chemistry
15. Hot-Spotting with Thermal Scanning: A Ligand- and Structure-Independent Assessment of Target Ligandability
    Molly Chilton, Benjamin Clennell, Fredrik Edfeldt, Stefan Geschwindner · 2017 · Journal of Medicinal Chemistry
16. DNA-encoded C H functionality via photoredox-mediated hydrogen atom transformation catalysis
    Jinming Shan, Xing Ling, Jiaxiang Liu, Xuan Wang, Xiaojie Lu · 2021 · Bioorganic & Medicinal Chemistry
17. Kinetic capillary electrophoresis in screening oligonucleotide libraries for protein binders
    An T. H. Le, Svetlana M. Krylova, Sergey N. Krylov · 2023 · TrAC Trends in Analytical Chemistry
18. Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds
    Ashley L. Ramos, Eric R. Goedken, Kristine E. Frank, M.A. Argiriadi, Sana Bazzaz, Zhiguo Bian, Jesse T. C. Brown, Paolo A. Centrella, Hui-Ju Chen, Jeremy S. Disch et al. · 2024 · Journal of Medicinal Chemistry
19. Chemical Proteomics–Guided Discovery of Covalent Ligands for Cancer Proteins
    Xiaoyu Zhang, Benjamin F. Cravatt · 2024 · Annual Review of Cancer Biology
20. Selenium(II)‐Nitrogen Exchange (SeNEx) Chemistry: A Good Chemistry Suitable for Nanomole‐Scale Parallel Synthesis, DNA‐encoded Library Synthesis and Bioconjugation
    Wei Hou, Shaoneng Hou, Yuang Gu, Shuning Zhang, Peixiang Ma, Hai‐Yu Hu, Hongtao Xu · 2024 · ChemBioChem
21. A method for estimating binding affinity from primary DEL selection data
    Qiuxia Chen, Justin Hall, Timothy L. Foley, Jinqiao Wan, You Li, David I. Israel · 2020 · Biochemical and Biophysical Research Communications
22. Integrating DNA-encoded chemical libraries with virtual combinatorial library screening: Optimizing a PARP10 inhibitor
    Mike Lemke, Hannah Ravenscroft, Nicole J. Rueb, Dmitri Kireev, Dana V. Ferraris, Raphael M. Franzini · 2020 · Bioorganic & Medicinal Chemistry Letters
23. DNA-Encoded Library Technology: A Brief Guide to Its Evolution and Impact on Drug Discovery
    Robert A. Goodnow, Christopher P. Davie · 2017 · Annual reports in medicinal chemistry
24. Antibiotic Discovery with Synthetic Fermentation: Library Assembly, Phenotypic Screening, and Mechanism of Action of β-Peptides Targeting Penicillin-Binding Proteins
    Iain A. Stepek, Trung Cao, Anika Koetemann, Satomi Shimura, Bernd Wollscheid, Jeffrey W. Bode · 2019 · ACS Chemical Biology
25. Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening
    Inna V. Krieger, Subbarao Yalamanchili, Paige Dickson, Curtis A. Engelhart, Matthew D. Zimmerman, Jeremy Wood, Ethan Clary, Jasmine Nguyen, Natalie Thornton, Paolo A. Centrella et al. · 2024 · ACS Infectious Diseases
26. Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands
    Marco Catalano, Sebastian Oehler, Luca Prati, Nicholas Favalli, Gabriele Bassi, Jörg Scheuermann, Dario Neri · 2020 · Analytical Chemistry
27. Employing Photocatalysis for the Design and Preparation of DNA‐Encoded Libraries: A Case Study
    Dominik K. Kölmel, Hongyao Zhu, Mark E. Flanagan, Sylvie K. Ly Sakata, Anthony R. Harris, Jinqiao Wan, Barry A. Morgan · 2021 · The Chemical Record
28. How to Develop and Prove High-Efficiency Selection of Ligands from Oligonucleotide Libraries: A Universal Framework for Aptamers and DNA-Encoded Small-Molecule Ligands
    An T. H. Le, Svetlana M. Krylova, Stanislav S. Beloborodov, Tong Y. Wang, Ryan Hili, Philip E. Johnson, Feng Li, Rakesh Naduvile Veedu, Svetlana L. Belyanskaya, Sergey N. Krylov · 2021 · Analytical Chemistry
29. Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening
    Esther C. Y. Lee, Andrew J. McRiner, Katy E. Georgiadis, Julie X. Liu, Zooey Wang, Andrew D. Ferguson, Benjamin D. Levin, Moritz von Rechenberg, Christopher D. Hupp, Michael I. Monteiro et al. · 2021 · Journal of Medicinal Chemistry
30. DNA-Compatible Synthesis of α,β-Epoxyketones for DNA-Encoded Chemical Libraries
    Yuting Gao, Guixian Zhao, Pengyang He, Gong Zhang, Yangfeng Li, Yizhou Li · 2021 · Bioconjugate Chemistry
31. Affinity Enhancement of Protein Ligands by Reversible Covalent Modification of Neighboring Lysine Residues
    Alberto Dal Corso, Marco Catalano, Anja Sophie Schmid, Jörg Scheuermann, Dario Neri · 2018 · Angewandte Chemie
32. Computer-aided drug design: time to play with novel chemical matter
    Xavier Barril · 2017 · Expert Opinion on Drug Discovery
33. Evaluation of DNA encoded library and machine learning model combinations for hit discovery
    Sumaiya Iqbal, Wei Jiang, Eric Hansen, Tonia Aristotelous, Shuang Liu, Andrew G. Reidenbach, Cerise Raffier, Alison Leed, Chengkuan Chen, Lawrence Chung et al. · 2025 · npj Drug Discovery.
34. Functional Group Tolerance of a Micellar on-DNA Suzuki–Miyaura Cross-Coupling Reaction for DNA-Encoded Library Design
    James H. Hunter, Marco Potowski, Harriet A. Stanway‐Gordon, Andrew Madin, Garry Pairaudeau, Andreas Brunschweiger, Michael J. Waring · 2021 · The Journal of Organic Chemistry
35. Discovery of TIGIT inhibitors based on DEL and machine learning
    Feng Xiong, Mingao Yu, Honggui Xu, Zhenmin Zhong, Zhenwei Li, Yuhan Guo, Tianyuan Zhang, Zhixuan Zeng, Feng Jin, Xun He · 2022 · Frontiers in Chemistry
36. Impact of organic chemistry conditions on DNA durability in the context of DNA-encoded library technology
    Yashoda Krishna Sunkari, Thu-Lan Nguyen, Vijay Kumar Siripuram, Marc Flajolet · 2023 · iScience
37. Diversity-oriented synthesis encoded by deoxyoligonucleotides
    Liam Hudson, Jeremy W. Mason, Matthias V. Westphal, Matthieu J. R. Richter, Jonathan R. Thielman, Bruce K. Hua, Christopher J. Gerry, Guoqin Xia, Heather L. Osswald, John M. Knapp et al. · 2023 · Nature Communications
38. DNA-amphiphilic nanostructures: synthesis, characterization and applications
    Nishkarsh Jain, Ankur Singh, Dhiraj Devidas Bhatia · 2024 · Nanoscale
39. Methodology of drug screening and target identification for new necroptosis inhibitors
    Pengchao Pan, Zhenyu Cai, Chunlin Zhuang, Xiaofei Chen, Yifeng Chai · 2018 · Journal of Pharmaceutical Analysis
40. On-DNA Palladium-Catalyzed Hydrogenation-like Reaction Suitable for DNA-Encoded Library Synthesis
    Julián Priego, Eduardo de Pedro Beato, Jesús Benavides, Adrián Gironda-Martínez, Fernando González‐Pérez, Jesús de Blas, María Dolores Martín-Ortega, Ramón Rama-Garda, Jesús Ezquerra, Miguel Ángel Toledo et al. · 2020 · Bioconjugate Chemistry
41. Modular assembly and encoding strategies for dual-display DNA-encoded chemical libraries
    Sebastian Oehler, Louise Plais, Gabriele Bassi, Dario Neri, Jörg Scheuermann · 2021 · Chemical Communications
42. DNA-Compatible Diversification of Indole π-Activated Alcohols via a Direct Dehydrative Coupling Strategy
    Shuting Zhong, Xianfu Fang, Yiting Wang, Gong Zhang, Yangfeng Li, Yizhou Li · 2022 · Organic Letters
43. Rapid de novo discovery of peptidomimetic affinity reagents for human angiotensin converting enzyme 2
    Genwei Zhang, Joseph S. Brown, Anthony J. Quartararo, Chengxi Li, Xuyu Tan, Stephanie Hanna, Sarah Antilla, Amanda E. Cowfer, Andrei Loas, Bradley L. Pentelute · 2022 · Communications Chemistry
44. DNA Compatible Oxidization and Amidation of Terminal Alkynes
    Zhaomei Sun, Jie Zhang, Huanqing Zhang, Hongli Cao, Lingqian Xiao, Kexin Yang, Yun Jin Hu · 2022 · Bioconjugate Chemistry
45. tagFinder: A Novel Tag Analysis Methodology That Enables Detection of Molecules from DNA-Encoded Chemical Libraries
    Jorge Amigo, Ramón Rama-Garda, Xabier Bello, Beatriz Sobrino, Jesús de Blas, María Dolores Martín-Ortega, Theodore C. Jessop, Ángel Carracedo, Marı́a Isabel Loza, Eduardo Domínguez · 2018 · SLAS DISCOVERY
46. A Chemistry for Incorporation of Selenium into DNA‐Encoded Libraries
    Hongtao Xu, Yuang Gu, Shuning Zhang, Huan Xiong, Fei Ma, Fengping Lu, Qun Ji, Lili Liu, Peixiang Ma, Wei Hou et al. · 2020 · Angewandte Chemie
47. Stability of Oligonucleotide–Small Molecule Conjugates to DNA-Deprotection Conditions
    Lik Hang Yuen, Raphael M. Franzini · 2017 · Bioconjugate Chemistry
48. Discovery, affinity maturation and multimerization of small molecule ligands against human tyrosinase and tyrosinase-related protein 1
    Marco Catalano, Gabriele Bassi, Giulia Rotondi, Lyna Khettabi, María G. Dichiara, Patrizia Murer, Jörg Scheuermann, Montserrat Soler‐López, Dario Neri · 2020 · RSC Medicinal Chemistry
49. Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library
    Devan J. Shell, Justin M. Rectenwald, Peter H. Buttery, Rebecca L. Johnson, Caroline A. Foley, Shiva Krishna Reddy Guduru, Mélanie Uguen, Juanita Sanchez Rubiano, Xindi Zhang, Fengling Li et al. · 2022 · SLAS DISCOVERY
50. Development of a Micellar-Promoted Heck Reaction for the Synthesis of DNA-Encoded Libraries
    Harriet A. Stanway‐Gordon, Jake A. Odger, Michael J. Waring · 2023 · Bioconjugate Chemistry
51. Ideal‐filter capillary electrophoresis: A highly efficient partitioning method for selection of protein binders from oligonucleotide libraries
    An T. H. Le, Svetlana M. Krylova, Sergey N. Krylov · 2019 · Electrophoresis
52. Determination of the Equilibrium Constant and Rate Constant of Protein–Oligonucleotide Complex Dissociation under the Conditions of Ideal-Filter Capillary Electrophoresis
    An T. H. Le, Svetlana M. Krylova, Sergey N. Krylov · 2019 · Analytical Chemistry
53. Fragment expansion with NUDELs – poised DNA-encoded libraries
    Catherine L. A. Salvini, Benoit Darlot, Jack R. Davison, Mathew P. Martin, Susan J. Tudhope, Shannon Turberville, Akane Kawamura, Martin E. M. Noble, Stephen R. Wedge, James J. Crawford et al. · 2023 · Chemical Science
54. Building Block-Based Binding Predictions for DNA-Encoded Libraries
    Chris Zhang, Mary Pitman, Anjali Dixit, Sumudu P. Leelananda, Henri Palacci, Meghan Lawler, Svetlana L. Belyanskaya, LaShadric C. Grady, Joe Franklin, Nicolas Tilmans et al. · 2023 · Journal of Chemical Information and Modeling
55. A Point of Inflection and Reflection on Systems Chemical Biology
    Eachan O. Johnson, Deborah Tan Hung · 2019 · ACS Chemical Biology
56. Click Nucleic Acid–DNA Binding Behavior: Dependence on Length, Sequence, and Ionic Strength
    Heidi R. Culver, Jasmine Sinha, Tania R. Prieto, Christopher J. Calo, Benjamin D. Fairbanks, Christopher N. Bowman · 2020 · Biomacromolecules
57. Immunoassay of Small Molecule Mediated by a Triply Functional DNA
    Yapiao Li, Fangzhi Yu, Shaokun Chen, Ning Zhang, Hailin Wang, Qiang Zhao · 2021 · Analytical Chemistry
58. Improved Diazo-Transfer Reaction for DNA-Encoded Chemistry and Its Potential Application for Macrocyclic DEL-Libraries
    Selahattin Ede, Mandy Schenk, Donald E. Bierer, Hilmar Weinmann, Keith Graham · 2021 · Molecules
59. Combinatorial technology revitalized by DNA‐encoding
    Árpád Furka · 2021 · MedComm
60. Design and construction of a stereochemically diverse piperazine-based DNA-encoded chemical library
    Srinivas Chamakuri, Mee‐Kyung Chung, Errol L. G. Samuel, Kevin A. Tran, Ying‐Chu Chen, Pranavanand Nyshadham, Conrad Santini, Martin Matthew Matzuk, Damian W. Young · 2021 · Bioorganic & Medicinal Chemistry
61. Learning the structure–activity relationship (SAR) of the Wittig reaction from genetically-encoded substrates
    Kejia Yan, Vivian Triana, Sunil V. Kalmady, Kwami Aku-Dominguez, Sharyar Memon, Alex Brown, Russell Greiner, Ratmir Derda · 2021 · Chemical Science
62. Programming DNA‐Based Systems through Effective Molarity Enforced by Biomolecular Confinement
    Marianna Rossetti, Alessandro Bertucci, Tania Patiño, Lorena Baranda Pellejero, Alessandro Porchetta · 2020 · Chemistry - A European Journal
63. Highly efficient photonic PCR system based on plasmonic heating of gold nanofilms
    Joshua Nabuti, Ahmed Mohamed Rashad Fath El-Bab, Ahmed Lotfy Abdel-Mawgood, Yoshihisa Matsushita, Hossam M. H. Shalaby · 2023 · Biosensors and Bioelectronics X
64. De Novo Generation of Chemical Structures of Inhibitor and Activator Candidates for Therapeutic Target Proteins by a Transformer-Based Variational Autoencoder and Bayesian Optimization
    Yuki Matsukiyo, Chikashige Yamanaka, Yoshihiro Yamanishi · 2023 · Journal of Chemical Information and Modeling
65. Hydrophobic Surfactant–DNA Complex (Surf-DNA) Enables DNA-Encoded-Library-Compatible Decarboxylative Arylation under Anhydrous Conditions
    Pratik Rajesh Chheda, Nicholas Simmons, Zhicai Shi · 2024 · Organic Letters
66. Challenges of antibacterial drug discovery
    Folkert Reck, Johanna M. Jansen, Heinz E. Moser · 2019 · ARKIVOC
67. N‐Alkyl Linkers for DNA‐Encoded Chemical Libraries
    Zhaomei Sun, Shao‐Guang Yang, Lijun Xue, Jie Zhang, Kexin Yang, Yun Jin Hu · 2022 · Chemistry - An Asian Journal
68. On-DNA hydroalkylation of N -vinyl heterocycles via photoinduced EDA-complex activation
    Mohammed Sharique, Bianca T. Matsuo, Albert Granados, Saegun Kim, Mahwish Arshad, Hyunjung Oh, Victoria E. Wu, Minxue Huang, Adam Csakai, Lisa A. Marcaurelle et al. · 2023 · Chemical Science
69. DNA-Compatible Copper-Catalyzed Oxidative Amidation of Aldehydes with Non-Nucleophilic Arylamines
    Ke Li, Yi Qu, Yulong An, Eric C. Breinlinger, Matthew P. Webster, Huanan Wen, Duanchen Ding, Meng Qi Zhao, Xiaodong Shi, Jiangong Wang et al. · 2020 · Bioconjugate Chemistry
70. Evaluating and evolving a screening library in academia: the St Jude approach
    Gisele Nishiguchi, Sourav Das, Jason Ochoada, Heather Long, Richard E. Lee Jr., Zoran Ranković, Anang A. Shelat · 2021 · Drug Discovery Today
71. Native Mass Spectrometry Facilitates Hit Validation in DNA‐Encoded Library Technology
    Philipp Bittner, Andreas Gloger, Michelle Keller, Sebastian Oehler, Alice Lessing, Qi Zhang, Zhongyao Ma, Wenji Su, Alexander Lee Satz, Letian Kuai et al. · 2025 · Angewandte Chemie International Edition
72. Impact of library input on the hit discovery rate in DNA-encoded chemical library selections
    Sara Puglioli, Sebastian Oehler, Luca Prati, Jörg Scheuermann, Gabriele Bassi, Samuele Cazzamalli, Dario Neri, Nicholas Favalli · 2023 · Chemical Science
73. Micelle‐Promoted Reductive Amination of DNA‐Conjugated Amines for DNA‐Encoded Library Synthesis
    Matthew J. Anderson, Thomas P. Carton, Catherine L. A. Salvini, James J. Crawford, Garry Pairaudeau, Michael J. Waring · 2024 · Chemistry - A European Journal
74. DNA-Compatible Cyclization Reaction to Access 1,3,4-Oxadiazoles and 1,2,4-Triazoles
    Gaonan Wang, Yu Tan, Hanzhi Zou, Xihang Sui, Zhanlong Wang, Alexander Lee Satz, Letian Kuai, Wenji Su, Qi Zhang · 2024 · Organic Letters
75. Discovery Small-Molecule p300 Inhibitors Derived from a Newly Developed Indazolone-Focused DNA-Encoded Library
    Yanrui Suo, Kaige Li, Xing Ling, Ke‐Nian Yan, Weiwei Lu, Jinfeng Yue, Xiaohua Chen, Zhiqiang Duan, Xiaojie Lu · 2024 · Bioconjugate Chemistry
76. On-DNA Mannich Reaction for DNA-Encoded Library Synthesis
    Danila Ryzhikh, Hyewon Seo, Jihoon Lee, Jieon Lee, Myung Hee Nam, Minsoo Song, Gil Tae Hwang · 2024 · The Journal of Organic Chemistry
77. Maximizing the integration of virtual and experimental screening in hit discovery
    Dávid Bajusz, György Miklós Keserű · 2022 · Expert Opinion on Drug Discovery
78. Autonome Entdeckung in den chemischen Wissenschaften, Teil I: Fortschritt
    Connor W. Coley, Natalie S. Eyke, Klavs F. Jensen · 2019 · Angewandte Chemie
79. Ideal‐Filter Capillary Electrophoresis (IFCE) Facilitates the One‐Step Selection of Aptamers
    An T. H. Le, Svetlana M. Krylova, Mirzo Kanoatov, Shrey P. Desai, Sergey N. Krylov · 2018 · Angewandte Chemie
80. Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen
    Koen F. W. Hekking, Sergio Maroto, Kees van Kekem, Frank S. Haasjes, Jack C. Slootweg, Patrick G. B. Oude Alink, Ron P. Dirks, Malvika Sardana, Marjon G. Bolster, Brian H. M. Kuijpers et al. · 2024 · Journal of Medicinal Chemistry
81. sp3‐Rich Heterocycle Synthesis on DNA: Application to DNA‐Encoded Library Production
    Felix Gruber, Anthony W. McDonagh, Victoria E. Rose, James H. Hunter, Laura Guasch, Rainer E. Martin, Stefanie N. Geigle, Robert Britton · 2024 · Angewandte Chemie International Edition
82. Ligandability Assessment of IL-1β by Integrated Hit Identification Approaches
    Anna Vulpetti, Jean‐Michel Rondeau, Marie-Hélène Bellance, Jutta Blank, Ralf Boesch, Andreas Boettcher, Frédéric Bornancin, Sylvia Buhr, Lauren E. Connor, Christoph E. Dumelin et al. · 2024 · Journal of Medicinal Chemistry
83. Enhancing the Predictive Power of Machine Learning Models through a Chemical Space Complementary DEL Screening Strategy
    Yanrui Suo, Qian Xu, Zhaoping Xiong, Xiaohong Liu, Chao Wang, Baiyang Mu, Xinyuan Wu, Weiwei Lu, Meiying Cui, Jiaxiang Liu et al. · 2024 · Journal of Medicinal Chemistry
84. Development of a DNA-encoded library screening method “DEL Zipper” to empower the study of RNA-targeted chemical matter
    Zhongyao Ma, Bin Zou, Jiannan Zhao, Rui Zhang, Qiaoqiao Zhu, Xiaofeng Wang, Linan Xu, Xiang Gao, Xinyue Hu, Wei Feng et al. · 2024 · SLAS DISCOVERY
85. Discovery of selective low molecular weight interleukin-36 receptor antagonists by encoded library technologies
    Juraj Velcicky, Gregor S. Cremosnik, Clemens Scheufler, Peter J. Meier, Emmanuelle Wirth, Richard Felber, Paul Ramage, Michael Schaefer, Christian Kaiser, Sylvie Lehmann et al. · 2025 · Nature Communications
86. Encoded Display of Chemical Libraries on Nanoparticles as a Versatile Selection Tool To Discover Protein Ligands
    KangJu Lee, Hee Myeong Wang, Minkyung Kim, Junhyung Park, Jungyeon Kim, Seungyoon Jang, Dahye Im, Beomjoon Goh, Min Hyeon Shin, Ji Hoon Shim et al. · 2025 · Journal of the American Chemical Society
87. Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy
    Noel J. Byrne, Amy C. Lee, James C. Kostas, John C. Reid, Andrea T. Partridge, Sung‐Sau So, Joseph E. Cowan, Pravien D. Abeywickrema, Hua Huang, Matthias Zebisch et al. · 2020 · Protein Expression and Purification
88. Constructing Head-to-Tail Cyclic Peptide DNA-Encoded Libraries Using Two-Directional Synthesis Strategy
    Wang Liu, Xiaopeng Bai, Liping Song, Xuan Wang, Xiaojie Lu · 2022 · Bioconjugate Chemistry
89. Targeting hippocampal neurogenesis to protect astronauts’ cognition and mood from decline due to space radiation effects
    McNerlin, Clare, Guan, Fada, Bronk, Lawrence, Lei, Kevin, Grosshans, David, Young, Damian W., Gaber, M. Waleed, Maletic-Savatic, Mirjana · 2022 · Life Sciences in Space Research
90. Synthetic Biology: A Solution for Tackling Nanomaterial Challenges
    Benjamin Lambert, Alice J. Gillen, Ardemis Anoush Boghossian · 2020 · The Journal of Physical Chemistry Letters
91. Divergent On-DNA Transformations from DNA-Linked Piperidones
    Xing Ling, Weiwei Lu, Lin Miao, Lisa A. Marcaurelle, Xuan Wang, Yun Ding, Xiaojie Lu · 2021 · The Journal of Organic Chemistry
92. Evaluation of the Topology Space of DNA-Encoded Libraries
    William K. Weigel, Alba L. Montoya, Raphael M. Franzini · 2023 · Journal of Chemical Information and Modeling
93. Synthesis of a DNA‐Encoded Library of Pyrrolo[2,3‐d]pyrimidines
    Junhyung Park, Hee Myeong Wang, Min Hyeon Shin, Hyun‐Suk Lim · 2021 · Bulletin of the Korean Chemical Society
94. Dual Bcl-XL /Bcl-2 inhibitors discovered from DNA-encoded libraries using a fragment pairing strategy
    Jean‐Pierre Daguer, Arthur Gonse, Yevhenii Shchukin, Lluc Farrera Soler, Sofía Barluenga, Nicolas Winssinger · 2021 · Bioorganic & Medicinal Chemistry
95. Affinity Selection from Synthetic Peptide Libraries Enabled by De Novo MS/MS Sequencing
    Li Quan Koh, Yi Wee Lim, Zachary P. Gates · 2022 · International Journal of Peptide Research and Therapeutics
96. PepScaf: Harnessing Machine Learning with In Vitro Selection toward De Novo Macrocyclic Peptides against IL-17C/IL-17RE Interaction
    Silong Zhai, Yahong Tan, Chengyun Zhang, Christopher J. Hipolito, Lulu Song, Cheng Zhu, You‐Ming Zhang, Hongliang Duan, Yizhen Yin · 2023 · Journal of Medicinal Chemistry
97. Compositional Deep Probabilistic Models of DNA-Encoded Libraries
    Benson Chen, Mohammad Muneeb Sultan, Theofanis Karaletsos · 2024 · Journal of Chemical Information and Modeling
98. Light-induced β-hydroxy sulfone synthesis in DNA-encoded libraries
    Lijun Xue, Jiaqing Yu, Ying Zhong, Junyun Chen, Chao Li, Kexin Yang, Nicolas Duchemin, Yun Jin Hu · 2024 · Chemical Communications
99. DNA‐Encoded Libraries: Hydrazide as a Pluripotent Precursor for On‐DNA Synthesis of Various Azole Derivatives
    Fei Ma, Jie Li, Shuning Zhang, Yuang Gu, Tingting Tan, Wanting Chen, Shuyue Wang, Peixiang Ma, Hongtao Xu, Guang Yang et al. · 2021 · Chemistry - A European Journal
100. DELs enable the development of BRET probes for target engagement studies in cells
     Kelly A. Teske, Wenji Su, Cesear R. Corona, Jing Wen, Jason Deng, Yan Ping, Zaihong Zhang, Qi Zhang, Jennifer Wilkinson, Michael Beck et al. · 2023 · Cell chemical biology