The DOI matches its Crossref record; 147 of the 148 references it cites were found in a registry or an index.
The vagus nerve and the inflammatory reflex – linking immunity and metabolism
Open accessAbstract
The vagus nerve has an important role in regulation of metabolic homeostasis, and efferent vagus nerve-mediated cholinergic signalling controls immune function and proinflammatory responses via the inflammatory reflex. Dysregulation of metabolism and immune function in obesity are associated with chronic inflammation, a critical step in the pathogenesis of insulin resistance and type 2 diabetes mellitus. Cholinergic mechanisms within the inflammatory reflex have, in the past 2 years, been implicated in attenuating obesity-related inflammation and metabolic complications. This knowledge has led to the exploration of novel therapeutic approaches in the treatment of obesity-related disorders.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The inflammation-sensing and inflammation-suppressing functions outlined above provide the principal components of the inflammatory reflex (71).”
From Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders (2018) · cites this paper as [71]
In the citing paper
“The appearance of pathogenic organisms activates innate immune cells that release cytokines. These in turn activate sensory fibers that ascend in the vagus nerve to synapse in the nucleus tractus solitarius. Increased efferent signals in the vagus nerve suppress peripheral cytokine release through macrophage nicotinic receptors and the CAIP.”
From Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders (2018) · cites this paper as [71]
In the citing paper
“there are both speculative (Pavlov and Tracey, 2012) and well-established (Felten, 1999) links between the autonomic and immune systems which could provide a mechanism for these results.”
From Effectiveness of a Novel Qigong Meditative Movement Practice for Impaired Health in Flight Attendants Exposed to Second-Hand Cigarette Smoke (2017) · cites this paper as Pavlov and Tracey, 2012
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Inflammation and metabolic disorders
Hotamisligil, G. S. (2006) · Nature · doi:10.1038/nature05485 · Cited by 9,199
Metabolic Endotoxemia Initiates Obesity and Insulin Resistance
Cani, P. D., Amar, J., Iglesias, M. A., Poggi, M., Knauf, C., Bastelica, D., Neyrinck, A. M., Fava, F., Tuohy, K. M., Chabo, C., et al. (2007) · Diabetes · doi:10.2337/db06-1491 · Cited by 6,638
Central nervous system control of food intake
Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451
Leptin and the regulation of body weight in mammals
Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405
The hormone resistin links obesity to diabetes
Steppan, C. M., Bailey, S. T., Bhat, S., Brown, E. J., Banerjee, R. R., Wright, C. M., Patel, H. R., Ahima, R. S., & Lazar, M. A. (2001) · Nature · doi:10.1038/35053000 · Cited by 4,755
Adipokines in inflammation and metabolic disease
Ouchi, N., Parker, J. L., Lugus, J. J., & Walsh, K. (2011) · Nature Reviews Immunology · doi:10.1038/nri2921 · Cited by 4,625
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
Borovikova, L. V., Ivanova, S., Zhang, M., Yang, H., Botchkina, G. I., Watkins, L. R., Wang, H., Abumrad, N., Eaton, J. W., & Tracey, K. J. (2000) · Nature · doi:10.1038/35013070 · Cited by 4,211
Self-citationInflammatory Mechanisms in Obesity
Gregor, M. F., & Hotamisligil, G. S. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101322 · Cited by 3,754
Type 2 diabetes as an inflammatory disease
Donath, M. Y., & Shoelson, S. E. (2011) · Nature Reviews Immunology · doi:10.1038/nri2925 · Cited by 3,737
Tracey, K. J. (2002) · Nature · doi:10.1038/nature01321 · Cited by 3,728
Self-citation
Flagged first, then by citations
1 of the 148 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 601–700 of 998
Neuro-immune interactions in cholinergic antiinflammatory pathway
Tuchina, O. P. (2020) · Genes and Cells · doi:10.23868/202003003 · Cited by 6
Medina-Rosales, M. N., Muñoz‐Ortega, M. H., García-Hernández, M. H., Talamás‐Rohana, P., Medina-Ramírez, I. E., Salas-Morón, L. G., Martínez-Hernández, S. L., Ávila‐Blanco, M. E., Medina-Rosales, B., & Ventura‐Juárez, J. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.586354 · Cited by 7
Multimodal Benefits of Exercise in Patients With Multiple Sclerosis and COVID-19
Razi, O., Tartibian, B., Laher, I., Govindasamy, K., Zamani, N., Rocha‐Rodrigues, S., Suzuki, K., & Zouhal, H. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.783251 · Cited by 6
Parasympathetic influences in cancer pathogenesis: further insights
Kumaria, A. (2021) · Clinical & Translational Oncology · doi:10.1007/s12094-020-02523-3 · Cited by 6
Bustamante, C., Bonilla, L. B. P., & Restrepo, J. C. (2024) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2024.1417856 · Cited by 5
Pasqualette, L. B. B. B., Fidalgo, T. K. D. S., Freitas‐Fernandes, L. B., Souza, G. G. L., Imbiriba, L. A., Lobo, L. A., Volchan, E., Domingues, R. M. C. P., Valente, A. P., & Miranda, K. R. (2024) · Metabolites · doi:10.3390/metabo14080450 · Cited by 5
Nahm, W. J., Kim, K. J., Namgung, E., Falanga, V., Chen, R., Lee, D. A., Schmitt, K., & Koo, J. (2025) · JAAD Case Reports · doi:10.1016/j.jdcr.2025.04.020 · Cited by 5
Dysregulated neural coding in the vagus nerve during long sepsis
Strohl, J. J., Huerta, T. S., Robbiati, S. F., & Huerta, P. T. (2025) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2025.101043 · Cited by 5
Zhang, C., Xu, H., Zheng, H.-F., Xiao-lian, W., Du, H.-G., & Jin, X. (2025) · PLoS ONE · doi:10.1371/journal.pone.0326357 · Cited by 5
Gudi, C. R., Wannemuehler, M. J., & Mansell, T. J. (2025) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2025.115650 · Cited by 5
Jin, X., Huang, Y., Luo, L., Tang, W., Chong, T. K., Pan, C., Liu, K., & Chen, J. (2026) · Translational research · doi:10.1016/j.trsl.2026.02.004 · Cited by 5
Chen, G., Yan, Y., Liu, S., He, Y., & Ma, T. (2026) · Journal of Inflammation Research · doi:10.2147/jir.s583388 · Cited by 5
Huang, Y., Dong, S., Li, X., Shi, J., Zhang, Y., Liu, S., Zhang, Y., & Yu, J. (2023) · The FASEB Journal · doi:10.1096/fj.202301623r · Cited by 5
Impact of Psilocybin on Peripheral Cytokine Production
DiRenzo, D., Barrett, F. S., Perin, J., Darrah, E., Christopher‐Stine, L., & Griffiths, R. R. (2024) · Psychedelic Medicine · doi:10.1089/psymed.2023.0039 · Cited by 6
Microfluidic compartmentalization of rat vagal afferent neurons to model gut-brain axis
Girardi, G., Zumpano, D., Raybould, H. E., & Şeker, E. (2024) · Bioelectronic Medicine · doi:10.1186/s42234-023-00140-3 · Cited by 5
Perrotta, M., & Carnevale, D. (2021) · Antioxidants and Redox Signaling · doi:10.1089/ars.2021.0142 · Cited by 5
Lucini, D., Spataro, A., Giovanelli, L., Malacarne, M., Spada, R., Parati, G., Solaro, N., & Pagani, M. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12091508 · Cited by 9
Fatemikia, H., Dehghanian, A., Ziaian, B., Farokhipour, M., & Ketabchi, F. (2022) · BMC Pulmonary Medicine · doi:10.1186/s12890-022-02151-3 · Cited by 5
Rasmussen, V. F., Hirschberg, V., Thrysøe, M., Vestergaard, E. T., Størling, J., & Kristensen, K. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-074992 · Cited by 5
Use of Extracellular Monomeric Ubiquitin as a Therapeutic Option for Major Depressive Disorder
Maldonado-García, J. L., García-Mena, L. H., Cabrera, D. M., Pérez‐Sánchez, G., Becerril‐Villanueva, E., Álvarez-Herrera, S., Homberg, T. A., Vallejo‐Castillo, L., Pérez‐Tapia, S. M., Moreno-Lafont, M. C., et al. (2024) · Pharmaceuticals · doi:10.3390/ph17070841 · Cited by 5
Vanderhasselt, M.-A., Vergauwe, R., Baeken, C., Pulopulos, M. M., & Raedt, R. D. (2025) · Clinical Psychology Review · doi:10.1016/j.cpr.2025.102611 · Cited by 6
Gärtner, F., Gihring, A., Roth, A., Bischof, J., Xu, P., Elad, L., Wabitsch, M., Burster, T., & Knippschild, U. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.745132 · Cited by 4
Schick, B., Barth, E., Mayer, B., Weber, C.-L., Hagemeyer, T., & Schönfeldt‐Lecuona, C. (2021) · BMJ Open · doi:10.1136/bmjopen-2021-050501 · Cited by 5
Álvarez, M. R., Alarcón, J. M., Roman, C. A. J., Lazaro, D. M., Bobrowski‐Khoury, N., Baena-Caldas, G. P., & Esber, G. R. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106525 · Cited by 5
Shpaner, M., Tulipani, L. J., Bishop, J. H., & Naylor, M. R. (2017) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-017-0126-5 · Cited by 5
Rhythmic liver drives feeding behavior
Martínez‐Sánchez, N., & Ray, D. W. (2024) · Science · doi:10.1126/science.adt0743 · Cited by 5
Lai, Y., Zhou, S., Tian, L., Li, H., Ye, X., & Che, G. (2025) · BMC Cancer · doi:10.1186/s12885-025-13778-w · Cited by 4
Siqueira, B. S., Gomes, E. C. Z., Rentz, T., Malta, A., Mathias, P. C. D. F., Balbo, S. L., & Grassiolli, S. (2025) · The Scientific World JOURNAL · doi:10.1155/tswj/9910997 · Cited by 4
Perin, J. P., Pastora-Sesín, C., Kang, S., Navarro‐Flores, A., Fregni, F., & Pacheco‐Barrios, K. (2025) · Journal of Functional Morphology and Kinesiology · doi:10.3390/jfmk11010015 · Cited by 5
Pravin, V., Vellapandian, C., & Kumar, V. N. (2026) · Brain Research · doi:10.1016/j.brainres.2026.150168 · Cited by 4
Heart-brain axis pathophysiological understanding and clinical impact
Vancheri, F., Vancheri, S., Longo, G., Vancheri, E., & Henein, M. Y. (2026) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2026.1681715 · Cited by 4
Skin-brain dialogue in auto-inflammatory diseases: A new route to biomarkers?
Matar, S., Aractingi, S., Gaillard, R., & Petit, A. (2024) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2024.100906 · Cited by 4
Contemporary insights into neuroimmune interactions across development and aging
Yeo, X. Y., Choi, Y., Hong, Y., Kwon, H. N., & Jung, S. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1611124 · Cited by 5
Drapkina, O. M., Dzhioeva, O. N., Александровна, Р. Е., Shvartz, E. N., & Kiselev, A. R. (2023) · Complex Issues of Cardiovascular Diseases · doi:10.17802/2306-1278-2022-11-4-191-200 · Cited by 4
Bustamante, C., Pinilla, L., & Amaris, Ó. (2023) · Clinical Medicine Insights Case Reports · doi:10.1177/11795476231159584 · Cited by 4
COSTA, S. O., Chaves, W. F., Lopes, P. K. F., Silva, I., Burguer, B., Ignácio-Souza, L. M., Torsoni, A. S., Milanski, M., Rodrigues, H. G., Desai, M., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1273556 · Cited by 4
Vagus nerve stimulation: Potential for treating chronic wounds
Budhiraja, A., Mehta, A., Alhamo, M. A., Swedarsky, R., Dahle, S. E., & Isseroff, R. R. (2024) · Wound Repair and Regeneration · doi:10.1111/wrr.13151 · Cited by 4
Donepezil ameliorates gut barrier disruption in doxorubicin-treated rats
Suparan, K., Sriwichaiin, S., Thonusin, C., Sripetchwandee, J., Khuanjing, T., Maneechote, C., Nawara, W., Arunsak, B., Chattipakorn, N., & Chattipakorn, S. C. (2024) · Food and Chemical Toxicology · doi:10.1016/j.fct.2024.114741 · Cited by 4
Mireles, J. A. G., Lares‐Asseff, I., Espinoza, E. A. R., Castañeda, V. L., Hurtado, L. P. C., Gutiérrez, F. D. M. R., Sandoval-Cabrera, A., Fierro, I. V., Ávila, J. C. G., Arreola, C. C., et al. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1423049 · Cited by 5
Azevedo, N., & Medina-Ramírez, R. (2025) · Frontiers in Pain Research · doi:10.3389/fpain.2025.1410808 · Cited by 4
Gut Feelings: Linking Dysbiosis to Depression—A Narrative Literature Review
Bibolar, A. C., Nechita, V.-I., Lung, F. C., Crecan-Suciu, B. D., & Paunescu, R. (2025) · Medicina · doi:10.3390/medicina61081360 · Cited by 7
Yoga, Meditation, and Acupuncture for Male Reproductive Health
Dhawan, V., & Dada, R. (2020) · Springer eBooks · doi:10.1007/978-3-030-32300-4_48 · Cited by 4
Mandalaneni, K., & Rayi, A. (2021) · StatPearls · Cited by 4
Brain Regulation of Feeding and Energy Homeostasis
Myers, M. G., Olson, D. P., Low, M. J., & Elias, C. F. (2016) · Springer eBooks · doi:10.1007/978-3-319-11251-0_22 · Cited by 5
Arias-Colinas, M., Gea, A., Khattab, A., Vassallo, M., Allen, S. C., & Kwan, J. S. K. (2022) · Applied Sciences · doi:10.3390/app12073484 · Cited by 4
Tanimizu, N., Ichinohe, N., & Mitaka, T. (2023) · Scientific Reports · doi:10.1038/s41598-023-33882-w · Cited by 5
Seesing, M. F. J., Janssen, H. J. B., Geraedts, T. C. M., Weijs, T. J., van Ark, I., Leusink-Muis, T., Folkerts, G., Garssen, J., Ruurda, J. P. H., Nieuwenhuijzen, G. A. P., et al. (2023) · Nutrients · doi:10.3390/nu15102327 · Cited by 4
The Role of the Gut Microbiome in Bipolar Disorder and its Common Medical Comorbidities
Jones, G. H., Pinjari, O. F., Vecera, C. M., Smith, K., Barrera, A., & Machado‐Vieira, R. (2023) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2023.101078 · Cited by 5
Nayok, S. B., Sreeraj, V. S., Shivakumar, V., & Venkatasubramanian, G. (2023) · Indian Journal of Physiology and Pharmacology · doi:10.25259/ijpp_401_2022 · Cited by 4
Bové, M., Schiavone, S., Tucci, P., Agosti, L. P., Dimonte, S., Palmieri, M. A., Sikora, V., Matteo, M., Trabace, L., & Morgese, M. G. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115780 · Cited by 4
Brain Regulation of Feeding and Energy Homeostasis
Affinati, A. H., Elias, C. F., Olson, D. P., & Myers, M. G. (2023) · Springer eBooks · doi:10.1007/978-3-031-40116-9_22 · Cited by 4
Autonomic Function and Baroreflex Control in COVID-19 Patients Admitted to the Intensive Care Unit
Gelpi, F., Wu, M. A., Bari, V., Cairo, B., MARIA, B. D., Fossali, T., Colombo, R., & Porta, A. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13082228 · Cited by 4
Wu, S., Chen, W. T., Muo, C., & Hsu, C. Y. (2018) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14440 · Cited by 4
Janssen, H. J. B., Geraedts, T. C. M., Fransen, L. F. C., van Ark, I., Leusink-Muis, T., Folkerts, G., Garssen, J., Ruurda, J. P. H., Nieuwenhuijzen, G. A. P., van Hillegersberg, R., et al. (2024) · Immunologic Research · doi:10.1007/s12026-024-09523-3 · Cited by 3
Immunological Avalanches in Renal Immune Diseases
Viggiano, D., Iulianiello, P., Mancini, A., Iacuzzo, C., Apicella, L., Pietro, R. A. D., Hamzeh, S., Cacciola, G., Lippiello, E., Gigliotti, A., et al. (2025) · Biomedicines · doi:10.3390/biomedicines13041003 · Cited by 3
The Effect of Transcranial Direct Current Stimulation on Basketball Performance—A Scoping Review
Chmiel, J., & Buryta, R. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14103354 · Cited by 3
Xu, H., Li, T., Yang, M., Zheng, Y., Zhu, X., Chen, L., & Zhao, H. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1666658 · Cited by 3
Pongwattanapakin, K., Care, C., Sitticharoon, C., Wilasrusmee, K. T., Keadkraichaiwat, I., Maikaew, P., & Sririwichitchai, R. (2025) · Scientific Reports · doi:10.1038/s41598-025-21757-1 · Cited by 3
Lee, C., Hsiao, F.-T., Chen, C., & Tang, S. (2025) · Journal of Biomedical Science · doi:10.1186/s12929-025-01194-y · Cited by 3
Microbiota regulation of gut-brain neuroimmune crosstalk in early life
Ravisankar, P., Wong, D. S. H., & Zeng, M. Y. (2025) · International Immunology · doi:10.1093/intimm/dxaf076 · Cited by 4
Cheng, K. P., Deshmukh, A., Gholston, A. K., Settell, M. L., Knudsen, B. E., LaLuzerne, M., Trevathan, J. K., Suminski, A. J., Pelot, N. A., Grill, W. M., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-67823-0 · Cited by 3
A Possible Role for the Vagus Nerve in Physical and Mental Health
Förster, C. Y., & Shityakov, S. (2026) · Biomolecules · doi:10.3390/biom16010121 · Cited by 3
Do, M., & Tyler, W. J. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1731999 · Cited by 4
Zhao, Y., Sui, J.-F., Wu, D., Chen, M., Ni, J., Zhang, Y., Xin, S.-Y., & Fan, M. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1682356 · Cited by 4
Zou, X., Shi, M., Xiao, X., Lv, X., Yang, M., Tian, M., Xie, B., Wang, L., Wang, J., & Qin, D. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1775841 · Cited by 4
Hauser, R. A., Griffiths, M., Watterson, A., Matias, D. P., & Rawlings, B. R. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15062212 · Cited by 3
The hallmarks of neuro-immune reprogramming in cancer
Bautista, J., & López‐Cortés, A. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1806570 · Cited by 3
LIU, H. J., Li, X., Yu, J., & Chen, T. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1789297 · Cited by 3
Decoding the dialogue: The vagus nerve at the interface of brain, body, and Tumor
Dang, H.-R., & Jin, W.-L. (2026) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2026.101487 · Cited by 3
What’s the role of thymus in diabetes mellitus?
Dai, X., Li, H., Chen, H., Li, Q., Chen, W., & Liang, C. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.109765 · Cited by 3
Yu, X., & Kong, Q. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1197467 · Cited by 3
Can Electrical Stimulation Prevent Recurrence of Keloid Scars? A Scoping Review
George, R. E., Bay, C. C., Thornton, S. M., Knazze, J. T., Kane, N., Ludwig, K. A., Donnelly, D. T., Poore, S. O., & Dingle, A. M. (2024) · Advances in Wound Care · doi:10.1089/wound.2023.0203 · Cited by 3
Preoperative vagal activity predicts clinical outcomes after total knee replacement
Gitler, A., Levine, A., Ayub, A., Munteanu, A., Ben-Lulu, O., & Gidron, Y. (2024) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2024.12682 · Cited by 5
Altered control of breathing in a rat model of allergic lower airway inflammation
Morgan, B. J., Song, R., McDermott, I., Brinkman, J. A., Holbert, K., Oler, A. T., Dresen, A., Sandbo, N. K., Bernau, K., & Teodorescu, M. (2024) · Journal of Neurophysiology · doi:10.1152/jn.00301.2023 · Cited by 3
Kaushik, A. S., Agarwal, V., Kumar, N., Rehman, M., Chaudhary, R., Srivastava, S., Srivastava, S., & Mishra, V. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.151567 · Cited by 3
Heart Rate Variability, Affective Disorders and Health
Kemp, A. H. (2016) · Springer eBooks · doi:10.1007/978-3-319-32480-7_11 · Cited by 3
Shoulder transcutaneous electric nerve stimulation decreases heart rate via potentiating vagal tone
Hsieh, C.-M., Lin, W.-C., Peng, H., Chen, H., Ho, Y., Li, C.-J., Wu, X.-G., Chung, J.-Y., Lee, S., & Lin, T. (2021) · Scientific Reports · doi:10.1038/s41598-021-98690-6 · Cited by 3
Xie, X., Zhang, N., Fu, J.-Y., Wang, Z., Ye, Z., & Liu, Z. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1009527 · Cited by 3
Ghazvini, H., Zarghami, M., Rafaiee, R., Beirami, E., & Tamijani, S. M. S. (2022) · Iranian Journal of Psychiatry and Behavioral Sciences · doi:10.5812/ijpbs-123423 · Cited by 3
Mateus, K. C. D. S., Bonfante, I. L. P., Sardeli, A. V., Duft, R. G., Gáspari, A. F., Trombeta, J. C. D. S., Morari, J., Rodrigues, B., Torsoni, M. A., Chacon‐Mikahil, M. P. T., et al. (2023) · Biomedicines · doi:10.3390/biomedicines11020565 · Cited by 3
Influence of Vagus Nerve Stimulation on Mood and Associated Disorders
Bottari, S. A., Rodriguez, A., & Williamson, J. B. (2023) · Neuromethods · doi:10.1007/978-1-0716-3465-3_7 · Cited by 4
Shah, A. M., Zamora, R., Barclay, D. A., Yin, J., El-Dehaibi, F., Addorisio, M. E., Tsaava, T., Tynan, A., Tracey, K. J., Chavan, S. S., et al. (2024) · Frontiers in Systems Biology · doi:10.3389/fsysb.2024.1266279 · Cited by 3
Self-citationTran, N. T., Somers, A., Vidinopoulos, K., Azman, Z., Pham, Y., Zahra, V. A., Chan, K. Y. Y., Hooper, S. B., Crossley, K. J., Allison, B. J., et al. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1397658 · Cited by 3
Santos‐de‐Araújo, A. D., Oliveira, M. R., Pontes‐Silva, A., Rodrigues, L. N., Costa, C. P. S., Marinho, R. S., dos Santos, S. D. S., Arena, R. A., Phillips, S. A., Dibai, D. B., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-77558-5 · Cited by 3
Liver Cancer Neuroscience: Regulating Liver Tumors via Selective Hepatic Vagotomy
Bauer, K. C., Ghabra, S., Ma, C., Chedester, L., & Greten, T. F. (2024) · Methods and Protocols · doi:10.3390/mps7060099 · Cited by 3
Silva, G. D. C., Ferreira, M. J., de Araújo, A. A., Nascimento-Filho, A. V., Bernardes, N., do Amaral, J. B., Irigoyen, M. C., & Angelis, K. D. (2025) · Autonomic Neuroscience · doi:10.1016/j.autneu.2025.103280 · Cited by 3
Vagus Nerve Stimulation and Regulation of Inflammation
Olofsson, P. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-805353-9.00125-x · Cited by 4
Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice
Relat, J., Come, J. A. A. D. S. S., Pérez, B., Camps, P., Muñoz‐Torrero, D., Badı́a, A., Giménez‐Llort, L., & Clos, M. V. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092615 · Cited by 3
Inflammatory response of the peripheral neuroendocrine system following downhill running
Minari, A. L. A., Avila, F., Oyama, L. M., & dos Santos, R. V. T. (2021) · Cytokine · doi:10.1016/j.cyto.2021.155746 · Cited by 3
Popovych, I. (2022) · Journal of Education Health and Sport · doi:10.12775/jehs.2022.12.04.019 · Cited by 3
Effects of Vagotomy and Fenugreek on Hyperlipidemia and Insulin Resistance
Khound, R. (2017) · Lincoln (University of Nebraska) · Cited by 3
Gonçalves, W. A., Melão, A. C. R., Teixeira, M. M., Rezende, B. M., & Pinho, V. (2018) · Springer eBooks · doi:10.1007/978-3-319-77658-3_6 · Cited by 3
Thinking small: Zinc sensing by the gut epithelium
Fernández‐Gallego, N., Sánchez‐Madrid, F., & Jiménez‐Saiz, R. (2020) · Allergy · doi:10.1111/all.14531 · Cited by 3
Predictive role of baroreflex sensitivity in the assessment of perioperative risk. Article
Zabolotskikh, I. B., & Владимирович, Т. Н. (2020) · Annals of critical care · doi:10.21320/1818-474x-2020-2-49-62 · Cited by 3
Changes in Subendocardial Viability Ratio in Traumatic Brain Injury Patients
Siwicka-Gieroba, D., Robba, C., Poleszczuk, J., Dębowska, M., Waniewski, J., Badenes, R., Jaroszyński, A., Piasek, E., Kotfis, K., Biernawska, J., et al. (2021) · Brain Connectivity · doi:10.1089/brain.2020.0850 · Cited by 3
Heart Rate Variability and Psychometric Analysis in Patients with Hyperactive Heart Fire Syndrome
Martínez, O. M., Fossión, R., Piceno, Y. G., Gómez, R. E. L., López-Espinosa, E., Jiménez‐Estrada, I., & Quiróz-González, S. (2021) · Journal of Acupuncture and Meridian Studies · doi:10.51507/j.jams.2021.14.4.137 · Cited by 3
Falvey, A., Palandira, S. P., Chavan, S. S., Brines, M. L., Tracey, K. J., & Pavlov, V. A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.17.541191 · Cited by 3
Self-citationVagal nerve stimulation potential therapeutic benefits in acute lung rejection and transplantation
Edalati, S., Meyer, J. S., Aravot, D., & Barac, Y. D. (2024) · Transplant Immunology · doi:10.1016/j.trim.2024.102105 · Cited by 2
Kong, W., Jing, X.-T., Zeng, P., Zeng, B., Mo, W., & Yang, H. (2024) · Journal of Voice · doi:10.1016/j.jvoice.2024.12.013 · Cited by 2
Focused Ultrasound Neuromodulation to Peripheral Nerve System
Zhou, Y. (2025) · European Journal of Neuroscience · doi:10.1111/ejn.70062 · Cited by 2
Metadata
- Authors
- Pavlov, V. A., & Tracey, K. J.
- Affiliations
- Feinstein Institute for Medical Research (US)
- Corresponding author
- Pavlov, Valentin A.
- Venue
- Nature Reviews Endocrinology
- Published
- 2012-11-21
- Volume
- 8
- Issue
- 12
- Pages
- 743-754
- ISSN
- 1759-5029 (ISSN-L)
- 1759-5037
- PMC
- PMC4082307
- OpenAlex
- W1981020037
- Cited by
- 1,040
- References
- 148
- Citations by year
- 2026: 149 · 2025: 121 · 2024: 111 · 2023: 87 · 2022: 96 · 2021: 88 · 2020: 82 · 2019: 59 · 2018: 73 · 2017: 60 · 2016: 33 · 2015: 37 · 2014: 25 · 2013: 17 · 2012: 1
- FWCI
- 2.38
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of General Medical Sciences (R01GM089807, R01GM057226)
- Topics
- Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- vagus nerve, cholinergic anti-inflammatory pathway, obesity, chronic inflammation, insulin resistance, type 2 diabetes, metabolic homeostasis, immune activation, vagus nerve stimulation therapy
- MeSH terms
- Animals, Diabetes Mellitus, Type 2, Homeostasis, Humans, Inflammation, Obesity, Reflex, Vagus Nerve, Signal Transduction, Metabolic Networks and Pathways
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review