Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence

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Evolution at Two Levels in Humans and Chimpanzees: Their macromolecules are so alike that regulatory mutations may account for their biological differences

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Widespread parallel evolution in sticklebacks by repeated fixation of Ectodysplasin alleles.

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Charting the human-specific properties of gene expression networks in the infant prefrontal cortex

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Genome-wide identification and characterization of the RNAi gene families in Brassica rapa L. highlighting their regulatory components and underlying functions involving crop improvement

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Downregulation is the dominant effect of new regulatory mutations in a fungal pathogen

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Genome-wide identification and characterization of 1-amino-cyclopropane-1- carboxylate synthase (ACS) gene family in Carica papaya and expression insights in response to hormone stress

Mudasar, M., Nabi, H. G., Ahmad, A., SHAFIQ, M., Shahzad, N., Abbas, Z., Ali, M., Ullah, I., Akbar, H., Ul‐Allah, S., et al. (2026) · BMC Plant Biology · doi:10.1186/s12870-026-09368-y

CD43: recent advances and emerging functions

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Identification of the R2R3-MYB transcription factor family in goji and LbaR2R3-MYB3 mediated wax biosynthesis enhancing powdery mildew resistance in tobacco

Wang, X., Li, J., Li, S., Zhang, X., Wang, J., Hou, T., & He, J. (2026) · Plant Cell Reports · doi:10.1007/s00299-026-03877-8

cis-Regulatory Elements in Crops: From Natural Variation to Precision Engineering

Boccaccini, A., Pizziconi, B., Molinari, M., Cimini, S., & Gara, L. D. (2026) · Agronomy · doi:10.3390/agronomy16131282

Genome-Wide Identification, Expression and Tissue-Specific Epigenetic Modification Analysis of the Su(var)3-9 SET Gene Family in Soybean

Wang, M., Zhou, W., Zhang, Z., Cao, L., Wang, L., Xie, L., Wu, J., Haoce, X., & Jia, N. (2026) · Biology · doi:10.3390/biology15131085

The RrHY5‐RrNAC2‐RrOSC5 Module Promotes UV‐B‐Induced Sterol Defence in Rosa roxburghii

Xin, D., Wu, X., Wang, L., Wang, J., Ning, Y., An, H., Sun, L., Yang, H., & Fu, Y. (2026) · Plant Cell & Environment · doi:10.1111/pce.70744

GENOME-WIDE EVALUATION OF THE YABBY TRANSCRIPTION FACTOR GENE FAMILY IN THEOBROMA CACAO AND COMPARATIVE ANALYSIS WITH ARABIDOPSIS THALIANA

HAYYAT, Q., AMJAD, M., & ZOHAIB, M. (2026) · Bulletin of Biological and Allied Sciences Research · doi:10.64013/bbasr.v2026i1.133

Genome-Wide Identification and Characterization of 14-3-3 Gene Family in Peanut

Li, L., Peng, J., & Chen, G. (2026) · Genes · doi:10.3390/genes17080901

Romantic love as regulatory co-option of maternal-bonding circuitry: a testable genetic account

Felesina, T., & Bode, A. (2026) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2026.1797790

GRAINS: Enabling High-Performance and Low-Cost Graph-Based Genome Analysis via Storage-Aware Algorithm-Architecture Co-Design

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Genome-Wide Identification and Characterization of the Wnt Gene Family in Donkey (Equus asinus): Phylogenetic Analysis and Expression Profiling

Zhu, Q., Jing, Y., Zheng, Y., Khan, M. Z., Liu, A., Peng, Y., & Wang, C. Z. (2026) · Biology · doi:10.3390/biology15151323

Regulatory activity and evolutionary co-option of cis-regulatory elements underlying bear hibernation

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Longitudinal genome-wide analysis reveals putative non-additive loci in trait development

Porneso, R. P. O., Havdahl, A., Eilertsen, E. M., & Ystrøm, E. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117840

Insights into Genotype-Phenotype Mapping and Evolvability: A Perspective of Neutral EvolutionPreprint

Deng, S. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.7308264

Genome-wide analysis of the S-RLK gene family and functional characterization of OsNRS1 in 9311 and Nipponbare

Chen, C., Jin, J., Shi, S., Li, Y., Dong, Q., Sun, H., Li, J., Kang, G., & Du, C. (2026) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2026.111659

A Gypsy LTR retrotransposon insertion in BrNYC1-A04 causes the stay-green phenotype by inhibiting chlorophyll b degradation in Chinese cabbage (Brassica rapa L. ssp. pekinensis)

Tao, P., Yue, Z., He, W., Feng, Y., Zhang, J., Lei, J., & Li, B. (2026) · Theoretical and Applied Genetics · doi:10.1007/s00122-026-05358-8

Editing cis-regulatory elements to enhance desired traits in plants

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iCUT&Tag-based pan-fruit epigenomic profiling identifies recurrent H3K9 acetylation enrichment during fleshy fruit ripening

Wang, J., Peng, T., Zhang, C., Gao, Y., Wu, H., Wei, C., Guan, X., & Zhang, B. (2026) · Plant Communications · doi:10.1016/j.xplc.2026.102078

Characterization of GmNPF genes prioritizes candidate genes for soybean yield and protein improvement

Wen, X., Wang, L., Zhang, Y., Wang, S., Wang, D., Xu, X., Huang, L., Xue, Y. J., Shor, E., Li, Y., et al. (2026) · Frontiers in Plant Science · doi:10.3389/fpls.2026.1926264

Parent-of-origin effects on allelic expression bias in interspecific poplar hybrids

Liu, X., Hong, S.-D., Cai, W.-X., Wu, Z., Guo, Y., Harding, S. A., Tsai, C., & Xue, L. (2026) · Tree Physiology · doi:10.1093/treephys/tpag128

Modular synthetic cross-kingdom promoters enable coordinated expression in Escherichia coli and Saccharomyces cerevisiae

Son, S., Moon, S. Y., An, N., & Lee, J. Y. (2026) · Nucleic Acids Research · doi:10.1093/nar/gkag868

Plant cis ‐regulatory grammar: Decoding the multidimensional code of transcriptional regulation for programmable crop engineering

Zhang, L., & Li, M. (2026) · Journal of Integrative Plant Biology · doi:10.1111/jipb.70386

Synthetic Orthogonal Promoters and Transcription Factor Platforms in Algae: Rational Design Principles and Applications in Synthetic Biology

Oliveira, V. P., & Winck, F. V. (2026) · SynBio · doi:10.3390/synbio4030017

Genome-Wide Identification and Characterization of the MAG2 Gene Family in Medicago sativa

Xu, C., Zhou, T., Huang, Y., Yang, Y., Liu, J., Lü, Y., Li, Q., Liu, X., & Zhang, B. (2026) · Genes · doi:10.3390/genes17091111

From reference-genome prediction to causal generalization: sequence-to-function models for plant regulatory genomics

Zhan, M., & Wu, R. (2026) · Frontiers in Plant Science · doi:10.3389/fpls.2026.1968878

Comparative Genomics and Heterologous Complementation Reveal Sequence and Structural Divergence of Selected Transcription Factors From Spathaspora passalidarum

Albuini, F. M., de Castro, A. G., Ribeiro, L. E., Gazolla, L. C. D. O. F., Rosa, C. A., Mendes, T. A. D. O., & Fietto, L. G. (2026) · Yeast · doi:10.1002/yea.70046

Chromatin Accessibility Reveals Adaptive Regulatory Variation in a Keystone Freshwater Fish

Taube, K., Noreikienė, K., López, M. E., Gross, R., & Vasemägi, A. (2026) · Molecular Ecology · doi:10.1111/mec.70550

Reconstructing sequence-grammar trajectories enables interpretable and tunable cis-regulatory element designPreprint

Ma, M., Bu, W., Liu, G., Liu, Y., Liu, S., Zhao, Z., Yao, S., Hua, Q., Zhang, Y., Zhong, C., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-10913378/v1

Genome-Wide Identification and Expression Profiling of the GATA Gene Family Reveals Candidate Genes Associated with GA3-Induced Shoot Elongation in Citrus grandis ‘Wanbai’

Ma, C., Xu, Y., Han, J., kong, Y., Yang, L., Feng, D., Fu, H., Hussain, S. B., Chen, P., & Guo, L. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27198542

Engineering Wheat for Compound Climate Extremes: Molecular Trade-Offs, Stress Memory, and Precision Genome Editing for Yield-Stable Resilience

Song, X., Hong, X., Wu, H., Su, P., & Sun, M. (2026) · Plants · doi:10.3390/plants15192936

Genome-Wide Identification and Expression Analysis of Kinase Proteins in Land Plants and Their Expression in Gossypium hirsutum Under Salt Stress

Nazar, A., Hussain, A., Ali, M. A., Shoukat, A., Ali, N., & Zaib-un-Nisa (2026) · Molecular Biotechnology · doi:10.1007/s12033-026-01613-x

Genome-Wide Identification of the Caffeoyl Coenzyme A 3-O-Methyltransferase Family Genes and Their Role in the Lodging Resistance of Wheat (Triticum aestivum L.)

Li, C., Sun, S., Wang, J., Wang, J., & Cui, H. (2026) · Plants · doi:10.3390/plants15192996

Cis-regulation and natural selection in the evolution of human DNA methylationPreprint

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Genome-Wide Evolution of Lineage-Specific Chromatin Accessibility Links Regulatory Changes to Cichlid Phenotypic Diversity

Mehta, T. K., Man, A., Etherington, G., Smith, A. M., Indermaur, A., Salzburger, W., Joyce, D. A., Palma, F. D., & Haerty, W. (2026) · Genome Biology and Evolution · doi:10.1093/gbe/evag247

The adaptive architecture of tRNA dependencies across physiological tumor environmentsPreprint

Chen, S., Charbonneau, T., Yousefi, K., Zirak, B., Lee, S., Joshi, T., Pawluk, A., Ramani, V., & Goodarzi, H. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.08.757597

Coherence, transformation, and breakdown in living systems: part II — predictions and implications for systemic health

Nicolaides, A. (2026) · Frontiers in Systems Biology · doi:10.3389/fsysb.2026.1910994

A relational architecture of the human genomePreprint

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Genome-wide identification of the BCAT gene family in Zygophyllum brachypterum and functional characterization of ZbBCAT2 in salt stress response

Miao, D., Ning, Q., Yang, Y., Cui, Z., Fiaz, I., Huang, W., & Jiao, P. (2026) · Frontiers in Plant Science · doi:10.3389/fpls.2026.1978750

KAS-Seq Maps Transcriptional Dynamics and Active Enhancers by Examining Single-Stranded DNA Landscapes

Wu, T., Lyu, R., & He, C. (2026) · Methods in molecular biology · doi:10.1007/978-1-0716-5627-3_7

Transcription factor-based genetic engineering in plants for development and stress tolerance

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CRISPR-based functional screening of noncoding regulatory elements

Roh, H., & Liau, B. B. (2026) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2026.102804

Identifying non-coding variant effects at scale via machine learning models of cis-regulatory reporter assays

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Genómica evolutiva de la regulación transcripcional en las principales familias multigénicas del sistema quimiosensorial de Drosophila

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Comparative genomics of gene regulation—conservation and divergence of cis-regulatory information

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Methods to Detect and Associate Divergence in Cis-Regulatory Elements to Phenotypic Divergence

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Transforming our understanding of species-specific gene regulation

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Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans

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