Regulation of immunity and inflammation by hypoxia in immunological niches

Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients

Locatelli, F., Fishbane, S. N., Block, G. A., & Macdougall, I. C. (2017) · American Journal of Nephrology · doi:10.1159/000455166 · Cited by 4,836

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Tannahill, G. M., Curtis, A. M., Adamik, J., Palsson-McDermott, E. M., McGettrick, A. F., Goel, G., Frezza, C., Bernard, N. J., Kelly, B., Foley, N. H., et al. (2013) · Nature · doi:10.1038/nature11986 · Cited by 4,176

Hypoxia-inducible factors in physiology and medicine

Semenza, G. L. (2012) · Cell · doi:10.1016/j.cell.2012.01.021 · Cited by 3,645

A guide to immunometabolism for immunologists

O'Neill, L. A. J., Kishton, R. J., & Rathmell, J. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2016.70 · Cited by 3,315

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.

Kaelin, W. G., & Ratcliffe, P. J. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.04.009 · Cited by 3,251

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Mills, E. L., Kelly, B., Logan, A., Costa, A. S. H., Varma, M., Bryant, C. E., Tourlomousis, P., Däbritz, J. H. M., Gottlieb, E., Latorre, I., et al. (2016) · Cell · doi:10.1016/j.cell.2016.08.064 · Cited by 2,291

Hypoxia and inflammation

Eltzschig, H. K., & Carmeliet, P. (2011) · New England Journal of Medicine · doi:10.1056/nejmra0910283 · Cited by 2,061

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia

Chandel, N. S., McClintock, D. S., Feliciano, C. E., Wood, T. M., Melendez, J. A., Rodriguez, A. M., & Schumacker, P. T. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001914200 · Cited by 2,000

Role of cellular, molecular and tumor microenvironment in hepatocellular carcinoma: Possible targets and future directions in the regorafenib era

Juengpanich, S., Topatana, W., Lu, C., Staiculescu, D., Li, S., Cao, J., Lin, J., Hu, J., Chen, M., Chen, J., et al. (2020) · International Journal of Cancer · doi:10.1002/ijc.32970 · Cited by 30

The HIF target ATG9A is essential for epithelial barrier function and tight junction biogenesis

Dowdell, A. S., Cartwright, I. M., Goldberg, M. S., Kostelecky, R. E., Ross, T., Welch, N., Glover, L. E., & Colgan, S. P. (2020) · Molecular Biology of the Cell · doi:10.1091/mbc.e20-05-0291 · Cited by 30

Hypoxia and hypoxia-inducible factor signals regulate the development, metabolism, and function of B cells

Zhang, J., Wu, X., Ma, J., Long, K., Sun, J., Li, M., & Ge, L. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.967576 · Cited by 33

Crosstalk between hypoxia-inducible factor-1α and short-chain fatty acids in inflammatory bowel disease: key clues toward unraveling the mystery

Xiao, J., Guo, X., & Wang, Z. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1385907 · Cited by 31

Rod‐Shaped Microgel Scaffolds with Interconnective Pores and Oxygen‐generating Functions Promote Skin Wound Healing and Alleviate Hypertrophic Scar Formation

Kang, Y., Liu, X., Wang, J., Peng, P., Liang, M., Wang, Q., Zheng, W., Li, S., & Gao, C. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202413678 · Cited by 31

Hypoxia in chronic kidney disease: towards a paradigm shift?

Faivre, A., Scholz, C. C., & de Seigneux, S. (2020) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfaa091 · Cited by 29

Hypoxia response and acute lung and kidney injury: possible implications for therapy of COVID-19

Vecchio, L. D., & Locatelli, F. (2020) · Clinical Kidney Journal · doi:10.1093/ckj/sfaa149 · Cited by 32

Kidney Allograft Fibrosis: Diagnostic and Therapeutic Strategies

Saritas, T., & Kramann, R. (2021) · Transplantation · doi:10.1097/tp.0000000000003678 · Cited by 29

HIF-1α Regulates Osteogenesis of Periosteum-Derived Stem Cells Under Hypoxia Conditions via Modulating POSTN Expression

Zhuang, Y., Zhao, Z., Cheng, M., Li, M., Si, J., Lin, K., & Yu, H. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.836285 · Cited by 29

Metabolic reprogramming and macrophage polarization in granuloma formation

Nakamizo, S., & Kabashima, K. (2024) · International Immunology · doi:10.1093/intimm/dxae013 · Cited by 28

Prolonged exposure to hypoxia inhibits the growth of Pacific abalone by modulating innate immunity and oxidative status

Nam, S.-E., Haque, M. N., Lee, J. S., Park, H. S., & Rhee, J. (2020) · Aquatic Toxicology · doi:10.1016/j.aquatox.2020.105596 · Cited by 28

Modulation of inflammation by anti-TNF α mAb-dendrimer nanoparticles loaded in tyramine-modified gellan gum hydrogels in a cartilage-on-a-chip model

Oliveira, I. M., Carvalho, M. R., Fernandes, D. C., Abreu, C. M., Maia, F. R., Pereira, H., Caballero, D., Kundu, S. C., Reis, R. L., & Oliveira, J. M. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb00802a · Cited by 28

Bioinspired nano-painting on orthopedic implants orchestrates periprosthetic anti-infection and osseointegration in a rat model of arthroplasty

Zhang, S., Chai, Q., Man, Z., Tang, C., Li, Z., Zhang, J., Xu, X., Xu, X., Chen, C., Liu, Y., et al. (2022) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.134848 · Cited by 29

Roles of lncRNA LVBU in regulating urea cycle/polyamine synthesis axis to promote colorectal carcinoma progression

Meng, X., Peng, J., Xie, X., Yu, F., Wang, W., Pan, Q., Jin, H., Huang, X., Yu, H., Li, S., et al. (2022) · Oncogene · doi:10.1038/s41388-022-02413-8 · Cited by 28

Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3

Cartwright, I. M., Curtis, V. F., Lanis, J. M., Alexeev, E. E., Welch, N., Goldberg, M. S., Schaefer, R. E. M., Gao, R. Y., Chun, C. L., Fennimore, B. P., et al. (2019) · Mucosal Immunology · doi:10.1038/s41385-019-0237-2 · Cited by 28

Reoxygenation Modulates the Adverse Effects of Hypoxia on Wound Repair

Bai, Q., Gao, Q., Hu, F., Zheng, C., Sun, N., Chen, W., Liu, J., Zhang, Y., Wu, X., & Lu, T. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232415832 · Cited by 29

Inflammation in a ferroptotic environment

Wickert, A., Schwantes, A., Fuhrmann, D. C., & Brüne, B. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1474285 · Cited by 27

Hypoxia Shapes Autophagy in LPS-Activated Dendritic Cells

Monaci, S., Aldinucci, C., Rossi, D., Giuntini, G., Filippi, I., Ulivieri, C., Marotta, G., Sozzani, S., Carraro, F., & Naldini, A. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.573646 · Cited by 27

Integrated Proteotranscriptomics of Human Myometrium in Labor Landscape Reveals the Increased Molecular Associated With Inflammation Under Hypoxia Stress

Chen, L., Wang, L., Luo, Y., Huang, Q., Ji, K., Bao, J., & Liu, H. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.722816 · Cited by 27

Metabolic immunomodulation of macrophage functional plasticity in nonhealing wounds

Anders, C. B., Lawton, T., & Ammons, M. C. B. (2019) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0000000000000550 · Cited by 27

Unlocking antitumor immunity with adenosine receptor blockers

Remley, V. A., Linden, J. M., Bauer, T. W., & Dimastromatteo, J. (2023) · Cancer Drug Resistance · doi:10.20517/cdr.2023.63 · Cited by 27

An overview of biological research on hypoxia-inducible factors (HIFs)

Liu, Z., Wu, Z., Fan, Y., & Fang, Y. (2020) · Endokrynologia Polska · doi:10.5603/ep.a2020.0064 · Cited by 26

High-pressure oxygen rewires glucose metabolism of patient-derived glioblastoma cells and fuels inflammasome response

Arienti, C., Pignatta, S., Zanoni, M., Zamagni, A., Cortesi, M., Sarnelli, A., Romeo, A., Arpa, D., Longobardi, P., Bartolini, D., et al. (2021) · Cancer Letters · doi:10.1016/j.canlet.2021.02.019 · Cited by 27

CXCR4 promotes B cell viability by the cooperation of nuclear factor (erythroid-derived 2)-like 2 and hypoxia-inducible factor-1α under hypoxic conditions

Jang, J., Thuy, P. X., Lee, J., & Moon, E. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-03615-w · Cited by 25

Targeting Hypoxic Tumor Plasticity for Recapturing Photodynamic‐Immunotherapy Sensitivity via Fluorinated Polysensitizers

Zhang, L., Tang, L., Yu, C., Xiao, H., & Liu, C. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202310450 · Cited by 28

HIF2α is a direct regulator of neutrophil motility

Sormendi, S., Deygas, M., Sinha, A. N., Krüger, A., Kourtzelis, I., Lay, G. L., Bernard, M., Sáez, P. J., Gerlach, M., Franke, K., et al. (2021) · Blood · doi:10.1182/blood.2020007505 · Cited by 24

The physiological basis with uterine myometrium contractions from electro-mechanical/hormonal myofibril function to the term and preterm labor

Zangeneh, F. Z., & Hantoushzadeh, S. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e22259 · Cited by 28

Oxygen‐Releasing Hydrogels for Tissue Regeneration

Jiang, S., Zheng, Y., Xia, H., Liu, Z., Rao, S., Wang, Y., Sun, H., Lu, X., & Xie, C. (2024) · Advanced NanoBiomed Research · doi:10.1002/anbr.202300133 · Cited by 27

Single-cell RNA sequencing of baseline PBMCs predicts ICI efficacy and irAE severity in patients with NSCLC

Kim, G. D., Shin, S.-I., Sun, P., Lee, J. E., Chung, C., Kang, Y. E., Kang, D. H., & Park, J. (2025) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2025-011636 · Cited by 27

A Review of HIF-1α-Mediated Integration of Metabolic Reprogramming, Mitochondrial Function, and PI3K/Akt–MAPK–Nrf2–NF-κB Signaling

Ashraf, A., & Bruce, E. D. (2026) · Antioxidants · doi:10.3390/antiox15030378 · Cited by 29

Mechanisms controlling bacterial infection in myeloid cells under hypoxic conditions

Hayek, I., Schatz, V., Bogdan, C., Jantsch, J., & Lührmann, A. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03684-8 · Cited by 25

HIV-Infected Individuals on ART With Impaired Immune Recovery Have Altered Plasma Metabolite Profiles

Nyström, S. N., Govender, M., Yap, S. H., Kamarulzaman, A., Rajasuriar, R., & Larsson, M. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofab288 · Cited by 25

An emerging research: the role of hepatocellular carcinoma-derived exosomal circRNAs in the immune microenvironment

Xu, H.-Z., Lin, X., Xu, Y., Xue, H., Lin, S., & Xu, T. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1227150 · Cited by 27

Pregnancy as a susceptible state for thrombotic microangiopathies

Frimat, M., Gnemmi, V., Stichelbout, M., Provôt, F., & Fakhouri, F. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1343060 · Cited by 24

Thermosensitive Hydrogel with Programmable, Self‐Regulated HIF‐1α Stabilizer Release for Myocardial Infarction Treatment

Deng, K., Hua, Y., Gao, Y., Zheng, H., Jiang, Y., Wang, Y., Gao, C., Ren, T., & Zhu, Y. (2024) · Advanced Science · doi:10.1002/advs.202408013 · Cited by 25

Effects and Mechanisms of Five Psoralea Prenylflavonoids on Aging-Related Diseases

Zhou, Y., Zhu, L., Yuan, Y., Ling, S., & Xu, J. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/2128513 · Cited by 24

Graphene quantum dots alleviate ROS-mediated gastric damage

Choudhary, P., Biswas, S., Kandoth, N., Tayde, D., Chatterjee, A., Chattopadhyay, S., Das, A., Swarnakar, S., & Pramanik, S. K. (2022) · iScience · doi:10.1016/j.isci.2022.104062 · Cited by 24

BNIP3 mediates the different adaptive responses of fibroblast-like synovial cells to hypoxia in patients with osteoarthritis and rheumatoid arthritis

Deng, R., Wang, Y., Bu, Y., & Wu, H. (2022) · Molecular Medicine · doi:10.1186/s10020-022-00490-9 · Cited by 24

The Role of Local Inflammation and Hypoxia in the Formation of Hypertrophic Scars—A New Model in the Duroc Pig

Nischwitz, S. P., Fink, J., Schellnegger, M., Luze, H., Bubalo, V., Tetyczka, C., Roblegg, E., Holeček, C., Zacharias, M., Kamolz, L., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010316 · Cited by 24

Innate Immune System in the Pathogenesis of Non-Alcoholic Fatty Liver Disease

Ma, D. W., Ha, J., Yoon, K., Kang, I., Choi, T. G., & Kim, S. S. (2023) · Nutrients · doi:10.3390/nu15092068 · Cited by 26

Microbial‐Enabled Photosynthetic Oxygenation for Disease Treatment

Yang, Z., Li, P., Feng, W., & Chen, Y. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202305866 · Cited by 26

Interplay between Hypoxia and Extracellular Vesicles in Cancer and Inflammation

Venturella, M., Criscuoli, M., Carraro, F., Naldini, A., & Zocco, D. (2021) · Biology · doi:10.3390/biology10070606 · Cited by 24

Tuneable hydrogel patterns in pillarless microfluidic devices

Olaizola‐Rodrigo, C., Palma-Florez, S., Ranđelović, T., Bayona, C., Ashrafi, M., Samitier, J., Lagunas, A., Mir, M., Doblaré, M., Ochoa, I., et al. (2024) · Lab on a Chip · doi:10.1039/d3lc01082a · Cited by 24

Not just sugar: metabolic control of neutrophil development and effector functions

Ettel, P., & Weichhart, T. (2024) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiae057 · Cited by 26

Emodin in-situ delivery with Pluronic F-127 hydrogel for myocardial infarction treatment: Enhancing efficacy and reducing hepatotoxicity

Yao, Y. Q., Shao, F., Peng, X., Wang, H., Wang, K., & Zhu, K. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122963 · Cited by 23

Inflammasome Regulation: Therapeutic Potential for Inflammatory Bowel Disease

Xu, Q., Zhou, X., Strober, W., & Mao, L. (2021) · Molecules · doi:10.3390/molecules26061725 · Cited by 25

STAT3 governs the HIF-1α response in IL-15 primed human NK cells

Coulibaly, A., Velásquez, S. Y., Kassner, N., Schulte, J., Barbarossa, M. V., & Lindner, H. A. (2021) · Scientific Reports · doi:10.1038/s41598-021-84916-0 · Cited by 24

Gain-of-function Tibetan PHD2D4E;C127S variant suppresses monocyte function: A lesson in inflammatory response to inspired hypoxia

Bhattacharya, S., Shrimali, N. M., Mohammad, G., Koul, P. A., Prchal, J. T., & Guchhait, P. (2021) · EBioMedicine · doi:10.1016/j.ebiom.2021.103418 · Cited by 22

HIF1α-Dependent Induction of TFRC by a Combination of Intestinal Inflammation and Systemic Iron Deficiency in Inflammatory Bowel Disease

Fagundes, R. R., Bourgonje, A. R., Hu, S., Barbieri, R., Jansen, B. H., Sinnema, N., Blokzijl, T., Taylor, C. T., Weersma, R. K., Faber, K. N., et al. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.889091 · Cited by 23

Revisiting the “starved gut” hypothesis in inflammatory bowel disease

Colgan, S. P., Wang, R. X., Hall, C. H. T., Bhagavatula, G., & Lee, J. S. (2023) · Immunometabolism · doi:10.1097/in9.0000000000000016 · Cited by 23

Intersecting Pathways: The Role of Metabolic Dysregulation, Gastrointestinal Microbiome, and Inflammation in Acute Ischemic Stroke Pathogenesis and Outcomes

Nuszkiewicz, J., Kukulska-Pawluczuk, B., Piec, K., Jarek, D. J., Motolko, K., Szewczyk‐Golec, K., & Woźniak, A. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13144258 · Cited by 24

Novel insights into plasma biomarker candidates in patients with chronic mountain sickness based on proteomics

Zhang, P., Li, Z., Yang, F., Ji, L., Yang, Y., Liu, C., Liu, H., Ma, J., Liu, J., Dang, Z., et al. (2021) · Bioscience Reports · doi:10.1042/bsr20202219 · Cited by 22

Single‐Cell RNA‐Sequencing‐Aided Covalent Organic Frameworks‐Based Microneedle Design Targeting Phototherapy Resistant Tumor Cell

Zhang, B., Zhang, L., Wang, W., Yang, E., Song, A., Xiong, D., Yang, Q., Li, H., Deng, H., & Sun, Z. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202313890 · Cited by 22

Anti-Inflammatory Effects of Algae-Derived Biomolecules in Gut Health: A Review

Brizzi, A., Rispoli, R. M., Autore, G., & Marzocco, S. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26030885 · Cited by 23

A Straightforward Hypoxic Cell Culture Method Suitable for Standard Incubators

Matthiesen, S., Jahnke, R., & Knittler, M. R. (2021) · Methods and Protocols · doi:10.3390/mps4020025 · Cited by 24

A reduced level of the long non-coding RNA SNHG8 activates the NF-kappaB pathway by releasing functional HIF-1alpha in a hypoxic inflammatory microenvironment

Wang, C., Yang, Q., Han, Y., Liu, H., Wang, Y., Huang, Y., Zheng, Y., & Li, W. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-02897-x · Cited by 22

p53 lysine-lactylated modification contributes to lipopolysaccharide-induced proinflammatory activation in BV2 cell under hypoxic conditions

Fei, X., Chen, L., Gao, J., Jiang, X., Sun, W., Cheng, X., Zhao, T., Zhao, M., & Zhu, L. (2024) · Neurochemistry International · doi:10.1016/j.neuint.2024.105794 · Cited by 22

Mitochondria in hypoxic pulmonary hypertension, roles and the potential targets

Geng, Y., Hu, Y., Zhang, F., Tuo, Y., Ge, R., & Bai, Z. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1239643 · Cited by 26

Renal Organic Anion Transporters 1 and 3 In Vitro: Gone but Not Forgotten

Caetano-Pinto, P., & Stahl, S. H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242015419 · Cited by 23

Identification of Hypoxia‐ALCAMhigh Macrophage‐ Exhausted T Cell Axis in Tumor Microenvironment Remodeling for Immunotherapy Resistance

Xun, Z., Zhou, H., Shen, M., Liu, Y., Sun, C., Du, Y., Jiang, Z., Yang, L., Zhang, Q. H., Lin, C., et al. (2024) · Advanced Science · doi:10.1002/advs.202309885 · Cited by 27

Natural polysaccharides combined with mussel-inspired adhesion for multifunctional hydrogels in wound hemostasis and healing: A review

Chen, S., Xia, J., Hou, Z., Wu, P. Y., Yang, Y., Cui, L., Zheng, X., Sun, S., & Yang, L. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.136965 · Cited by 22

Oxygenation of the Transplanted Kidney

Rosenberger, C., & Eckardt, K. (2019) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2019.10.005 · Cited by 21

Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses

Strowitzki, M. J., Kimmer, G., Wehrmann, J., Ritter, A. S., Radhakrishnan, P., Opitz, V. M., Tuffs, C., Biller, M., Kugler, J., Keppler, U., et al. (2021) · JCI Insight · doi:10.1172/jci.insight.139191 · Cited by 24

Mycobacterium tuberculosis Load in Host Cells and the Antibacterial Activity of Alveolar Macrophages Are Linked and Differentially Regulated in Various Lung Lesions of Patients with Pulmonary Tuberculosis

Ufimtseva, E., Eremeeva, N. I., Umpeleva, T. V., Vakhrusheva, D. V., & Skornyakov, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073452 · Cited by 21

Myeloid hypoxia-inducible factor HIF1A provides cardio-protection during ischemia and reperfusion via induction of netrin-1

Heck‐Swain, K., Li, J., Ruan, W., Yuan, X., Wang, Y., Koeppen, M., & Eltzschig, H. K. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.970415 · Cited by 21

The journey from erythropoietin to 2019 Nobel Prize: Focus on hypoxia-inducible factors in the kidney

Pan, S., Chiang, W., & Chen, Y. (2020) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2020.06.006 · Cited by 24

Unprecedented Theranostic LaB6 Nanocubes‐Mediated NIR‐IIb Photodynamic Therapy to Conquer Hypoxia‐Induced Chemoresistance

Kuthala, N., Vankayala, R., Chiang, C., & Hwang, K. C. (2020) · Advanced Functional Materials · doi:10.1002/adfm.202002940 · Cited by 21

Oxygen‐Immunomodulated Nanocatalysts Enhance Anti‐Infection by Trained Immunity

Ruan, Z., Shi, T., Guo, Z., Zhu, Y., Wang, W., Ma, Y., Ding, C., Zhang, Y., Wang, X., Chen, Y., et al. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202509454 · Cited by 20

A comparative analysis of immune privilege in pregnancy and cancer in the context of checkpoint blockade immunotherapy

Flint, T. R., Jones, J. O., Ferrer, M., Colucci, F., & Janowitz, T. (2018) · Seminars in Oncology · doi:10.1053/j.seminoncol.2018.03.005 · Cited by 19

Hypoxia Induces Autophagy in Human Dendritic Cells: Involvement of Class III PI3K/Vps34

Monaci, S., Coppola, F., Rossi, D., Giuntini, G., Filippi, I., Marotta, G., Sozzani, S., Carraro, F., & Naldini, A. (2022) · Cells · doi:10.3390/cells11101695 · Cited by 19

How to tame your genes: mechanisms of inflammatory gene repression by glucocorticoids

Strickland, B. A., Ansari, S. A., Dantoft, W., & Uhlenhaut, N. H. (2022) · FEBS Letters · doi:10.1002/1873-3468.14409 · Cited by 22

Design of Nanoparticles in Cancer Therapy Based on Tumor Microenvironment Properties

Firouzabadi, B. M., Gigliobianco, M. R., Joseph, J. M., Censi, R., & Martino, P. D. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14122708 · Cited by 21

From acute SARS-CoV-2 infection to pulmonary hypertension

Egom, E. E. A., Shiwani, H. A., & Nouthé, B. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.1023758 · Cited by 20

Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress

Ehrenreich, H., Gassmann, M., Poustka, L., Burtscher, M., Hammermann, P., Sirén, A., Nave, K., & Miskowiak, K. W. (2023) · Neuroprotection/Neuroprotection (Chichester, England. Print) · doi:10.1002/nep3.15 · Cited by 19

Neutrophils as sources of dinucleotide polyphosphates and metabolism by epithelial ENPP1 to influence barrier function via adenosine signaling

Curtis, V. F., Cartwright, I. M., Lee, J. S., Wang, R. X., Kao, D. J., Lanis, J. M., Burney, K. M., Welch, N., Hall, C. H. T., Goldberg, M. S., et al. (2018) · Molecular Biology of the Cell · doi:10.1091/mbc.e18-06-0377 · Cited by 20

In vivo validation of a miniaturized electrochemical oxygen sensor for measuring intestinal oxygen tension

Gray, M., Marland, J. R. K., Dunare, C. C., Blair, E. O., Meehan, J., Tsiamis, A., Kunkler, I. H., Murray, A. F., Argyle, D. J., Dyson, A., et al. (2019) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00050.2019 · Cited by 20

The immunometabolic topography of cellular organization and bacterial control in tuberculosis granulomas

McCaffrey, E., Delmastro, A. C., Fitzhugh, I., Ranek, J. S., Douglas, S., Peters, J. M., Fullaway, C. C., Bosse, M. M., Liu, C. C., Gillen, C., et al. (2026) · Nature Immunology · doi:10.1038/s41590-026-02431-8 · Cited by 37

Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning

Spanoudaki, V. C., Doloff, J. C., Huang, W. X., Norcross, S., Farah, S., Langer, R., & Anderson, D. G. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1815909116 · Cited by 19

Alternative adenosine Receptor activation: The netrin-Adora2b link

Yuan, X., Mills, T., Doursout, M., Evans, S. E., Melo, M. F. V., & Eltzschig, H. K. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.944994 · Cited by 21

The hypoxic tissue microenvironment as a driver of mucosal inflammatory resolution

Cartwright, I. M., & Colgan, S. P. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1124774 · Cited by 18

Metabolism along the life journey of T cells

Peng, M., & Li, M. O. (2023) · Life Metabolism · doi:10.1093/lifemeta/load002 · Cited by 20

RNA binding protein DDX5 restricts RORγt + T reg suppressor function to promote intestine inflammation

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