The DOI matches its Crossref record; 129 of the 129 references it cites were found in a registry or an index.
Regulation of MHC class II gene expression by the class II transactivator
Open accessAbstract
MHC class II molecules are pivotal for the adaptive immune system, because they guide the development and activation of CD4+ T helper cells. Fulfilling these functions requires that the genes encoding MHC class II molecules are transcribed according to a strict cell-type-specific and quantitatively modulated pattern. This complex gene-expression profile is controlled almost exclusively by a single master regulatory factor, which is known as the class II transactivator. As we discuss here, differential activation of the three independent promoters that drive expression of the gene encoding the class II transactivator ultimately determines the exquisitely regulated pattern of MHC class II gene expression.
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Cited by
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The ins and outs of MHC class II-mediated antigen processing and presentation
Roche, P. A., & Furuta, K. (2015) · Nature reviews. Immunology · doi:10.1038/nri3818 · Cited by 1,207
Heme oxygenase–1 and carbon monoxide suppress autoimmune neuroinflammation
Chora, Â. A., Fontoura, P., Cunha, A., Pais, T. F., Cardoso, S., Ho, P. P., Lee, L. Y., Sobel, R. A., Steinman, L., & Soares, M. P. (2007) · Journal of Clinical Investigation · doi:10.1172/jci28844 · Cited by 306
Kitamura, N., Yokoyama, H., Yashiro, T., Nakano, N., Nishiyama, M., Kanada, S., Fukai, T., Hara, M., Ikeda, S., Ogawa, H., et al. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.10.019 · Cited by 55
The Immunomodulatory Effects of Statins on Macrophages
Sheridan, A., Wheeler-Jones, C. P. D., & Gage, M. C. (2022) · Immuno · doi:10.3390/immuno2020021 · Cited by 48
Metadata
- Authors
- Reith, W., LeibundGut-Landmann, S., & Waldburger, J.-M.
- Venue
- Nature Reviews Immunology
- Published
- 2005-10
- Volume
- 5
- Issue
- 10
- Pages
- 793-806
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2015848550
- Cited by
- 462
- References
- 129
- FWCI
- 0.92
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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