The DOI matches its Crossref record; 141 of the 141 references it cites were found in a registry or an index.
Colony-stimulating factors in inflammation and autoimmunity
Abstract
Although they were originally defined as haematopoietic-cell growth factors, colony-stimulating factors (CSFs) have been shown to have additional functions by acting directly on mature myeloid cells. Recent data from animal models indicate that the depletion of CSFs has therapeutic benefit in many inflammatory and/or autoimmune conditions and as a result, early-phase clinical trials targeting granulocyte/macrophage colony-stimulating factor and macrophage colony-stimulating factor have now commenced. The distinct biological features of CSFs offer opportunities for specific targeting, but with some associated risks. Here, I describe these biological features, discuss the probable specific outcomes of targeting CSFs in vivo and highlight outstanding questions that need to be addressed.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“CSF-1R-mediated signaling is critical for microglial development.”
From Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy (2020) · cites this paper as [17]
In the citing paper
“CSF-2 promotes migration of blood-borne monocytes across the blood-brain barrier, which then differentiate into macrophages in the presence of CSF-1 and CSF-2 [16, 17, 26, 52].”
From Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy (2020) · cites this paper as [17]
In the citing paper
“CSF-2 in isolation also promotes their differentiation into a dendritic cell lineage, which maintains a phagocytic phenotype (CD68 immunopositive) [17, 30].”
From Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy (2020) · cites this paper as [17]
In the citing paper
“Although pulmonary GM-CSF treatment has some drawbacks such as inflammatory activity (43) that can render its use in humans problematic by exacerbating inflammatory lung injury, the results of our study are promising.”
From Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections (2013) · cites this paper as [43]
Citations
Cites
Obesity is associated with macrophage accumulation in adipose tissue
Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041
Inflammation and metabolic disorders
Hotamisligil, G. S. (2006) · Nature · doi:10.1038/nature05485 · Cited by 9,199
MANTOVANI, A., SOZZANI, S., LOCATI, M., ALLAVENA, P., & SICA, A. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)02302-5 · Cited by 5,528
Inaba, K., Inaba, M., Romani, N., Aya, H., Deguchi, M., Ikehara, S., Muramatsu, S., & Steinman, R. M. (1992) · The Journal of Experimental Medicine · doi:10.1084/jem.176.6.1693 · Cited by 3,741
Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties
Geissmann, F., Jung, S., & Littman, D. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00174-2 · Cited by 3,504
Tumour-educated macrophages promote tumour progression and metastasis
Pollard, J. W. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1256 · Cited by 3,413
Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis
Condeelis, J. S., & Pollard, J. W. (2006) · Cell · doi:10.1016/j.cell.2006.01.007 · Cited by 2,677
Cytokines in the pathogenesis of rheumatoid arthritis
McInnes, I. B., & Schett, G. A. (2007) · Nature reviews. Immunology · doi:10.1038/nri2094 · Cited by 2,575
Takahashi, T., Kalka, C., Masuda, H., Chen, D., Silver, M., Kearney, M., Magner, M., Isner, J. M., & Asahara, T. (1999) · Nature Medicine · doi:10.1038/7434 · Cited by 2,421
Sherr, C. J., Rettenmier, C. W., Sacca, R. E., Roussel, M. F., Look, A. T., & Stanley, E. R. (1985) · Cell · doi:10.1016/s0092-8674(85)80047-7 · Cited by 1,539
Flagged first, then by citations
Cited by
Sorted by citations
Items 701–800 of 1,000
Wang, J., Xiang, Y., Wu, L., Zhang, C., Han, B., Cheng, Y., Tong, Y., Yan, D., & Wang, L. (2024) · European Journal of Clinical Nutrition · doi:10.1038/s41430-024-01486-w · Cited by 26
Cancer stem cells and tumor-associated macrophages: Interactions and therapeutic opportunities
Yuan, H., Qiu, Y., Mei, Z., Liu, J., Wang, L., Zhang, K., Liu, H., & Zhu, F. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.217737 · Cited by 23
Jobe, O., Trinh, H. V., Kim, J., AlSalmi, W., Tovanabutra, S., Ehrenberg, P. K., Peachman, K. K., Gao, G., Thomas, R., Kim, J. H., et al. (2015) · Journal of Leukocyte Biology · doi:10.1189/jlb.2a0815-361r · Cited by 22
The effects of exogenous fatty acids and niacin on human monocyte‐macrophage plasticity
la Paz, S. M., Rodriguez, D., Cardelo, M. P., Naranjo, M. C., Bermúdez, B., Abia, R., Muriana, F. J. G., & López, S. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600824 · Cited by 22
Popović, M., Yaparla, A., Paquin‐Proulx, D., Koubourli, D. V., Webb, R., Firmani, M. A., & Grayfer, L. (2019) · Journal of Leukocyte Biology · doi:10.1002/jlb.1a0919-147r · Cited by 23
Görgülü, N. G., & Doğan, B. (2022) · Journal of Periodontology · doi:10.1002/jper.21-0536 · Cited by 25
Stem Cell Transplantation for Lymphoma Patients with HIV Infection
Michieli, M., Mazzucato, M., Tirelli, U., & Paoli, P. D. (2010) · Cell Transplantation · doi:10.3727/096368910x528076 · Cited by 22
The yin-yang nature of CSF1R-binding cytokines
Zelante, T., & Ricciardi‐Castagnoli, P. (2012) · Nature Immunology · doi:10.1038/ni.2375 · Cited by 22
Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF
Félix, J., Kandiah, E., Munck, S. D., Bloch, Y., van Zundert, G. C. P., Pauwels, K., Dansercoer, A., Novanska, K., Read, R. J., Bonvin, A. M. J. J., et al. (2016) · Nature Communications · doi:10.1038/ncomms13228 · Cited by 22
Colony stimulating factors (CSFs): Complex roles in atherosclerosis
Singhal, A., & Subramanian, M. (2017) · Cytokine · doi:10.1016/j.cyto.2017.10.012 · Cited by 23
Fu, H., Tian, Y., Gao, Y., Li, C., & Liu, X. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.9963 · Cited by 22
Cojohari, O., Mahmud, J., Altman, A. M., Peppenelli, M. A., Miller, M. J., & Chan, G. C. T. (2020) · Viruses · doi:10.3390/v12060652 · Cited by 21
Biomaterials-Based Opportunities to Engineer the Pulmonary Host Immune Response in COVID-19
Jarai, B. M., Stillman, Z. S., Bomb, K., Kloxin, A. M., & Fromen, C. A. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c01287 · Cited by 22
Nair, J. R., Edwards, S. W., & Moots, R. J. (2012) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2012.732062 · Cited by 22
HIV‐1 Nef perturbs the function, structure, and signaling of the Golgi through the Src Kinase Hck
Hiyoshi, M., Takahashi‐Makise, N., Yoshidomi, Y., Chutiwitoonchai, N., Chihara, T., Okada, M., Nakamura, N., Okada, S., & Suzu, S. (2011) · Journal of Cellular Physiology · doi:10.1002/jcp.22825 · Cited by 21
Wu, Z., Hu, T., Chintoan‐Uta, C., Macdonald, J., Stevens, M. P., Sang, H., Hume, D. A., Kaiser, P., & Balic, A. (2021) · Immunology · doi:10.1111/imm.13426 · Cited by 21
M2 macrophages-derived exosomes regulate osteoclast differentiation by the CSF2/TNF-α axis
Zhou, Y., & Hu, G. (2024) · BMC Oral Health · doi:10.1186/s12903-023-03842-x · Cited by 24
Ginhoux, F., Ng, L. G., & Mérad, M. (2010) · Current topics in microbiology and immunology · doi:10.1007/82_2010_115 · Cited by 21
Hiyoshi, M., Hashimoto, M., Yukihara, M., Bhuyan, F., & Suzu, S. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.09.141 · Cited by 20
Endocrine and immune system interactions during pregnancy
Brazão, V., Kuehn, C. C., Santos, C. D., da Costa, C. M. B., Júnior, J. C. D. P., & Abrahão, A. A. C. (2014) · Immunobiology · doi:10.1016/j.imbio.2014.09.005 · Cited by 20
Growth hormone secretagogue receptor is important in the development of experimental colitis
Liu, Z.-Z., Wang, W., Li, Q., Tang, M., Li, J., Wu, W.-T., Wan, Y.-H., Wang, Z., Bao, S., & Fei, J. (2015) · Cell & Bioscience · doi:10.1186/s13578-015-0002-5 · Cited by 21
Interleukin-33 stimulates GM-CSF and M-CSF production by human endothelial cells
Montanari, E., Stojković, S., Kaun, C., Lemberger, C. E., de Martin, R., Rauscher, S., Gröger, M., Maurer, G., Neumayer, C., Huk, I., et al. (2016) · Thrombosis and Haemostasis · doi:10.1160/th15-12-0917 · Cited by 21
Wu, C., Yang, H., Huang, J., & Lai, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157960 · Cited by 21
Uitdehaag, J. C. M., Sünnen, C. M., van Doornmalen, A. M., de Rouw, N., Oubrie, A., Azevedo, R., Ziebell, M. R., Nickbarg, E. B., Karstens, W.-J. F., & Ruygrok, S. (2011) · SLAS DISCOVERY · doi:10.1177/1087057111418113 · Cited by 21
Miguel, L. I., Almeida, C. B., Traina, F., Canalli, A. A., Dominical, V. M., Saad, S. T. O., Costa, F. F., & Conran, N. (2011) · Inflammation Research · doi:10.1007/s00011-011-0315-8 · Cited by 21
Potential role of Th17 cells in the pathogenesis of type 2 autoimmune pancreatitis
Loos, M., Lauffer, F., Schlitter, A. M., Kleeff, J. H., Friess, H., Klöppel, G., & Esposito, I. (2015) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-015-1850-4 · Cited by 21
MafB antagonizes phenotypic alteration induced by GM-CSF in microglia
Koshida, R., Oishi, H., Hamada, M., & Takahashi, S. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.05.036 · Cited by 20
Fachi, J. L., de Oliveira, S., Gilfillan, S., Antonova, A. U., Hou, J., Vinolo, M. A. R., & Colonna, M. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2416182121 · Cited by 20
SOCS3 Attenuates GM-CSF/IFN-γ-Mediated Inflammation During Spontaneous Spinal Cord Regeneration
Zhang, X., He, B., Li, H., Wang, Y., Zhou, Y., Wang, W., Song, T., Gu, X., Gu, X., Luo, Y., et al. (2020) · Neuroscience Bulletin · doi:10.1007/s12264-020-00493-8 · Cited by 20
Kounis, N. G., Koniari, I. C., GREGORIO, C. D., Assimakopoulos, S. F., Velissaris, D., Hung, M., Mplani, V., Saba, L., Brinia, A., Kouni, S. N., et al. (2021) · Biomedicines · doi:10.3390/biomedicines9080959 · Cited by 19
Bueno, M. R., Ishikawa, K., Santos, G. D. A., Ando‐Suguimoto, E. S., Shimabukuro, N., Kawamoto, D., & Mayer, M. P. A. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.846192 · Cited by 20
Polarization of macrophages: mechanisms, markers and factors of induction
Fedorov, A. A., Ermak, N. A., Gerashchenko, T. S., Топольницкий, Е. Б., Шефер, Н. А., Родионов, Е. О., & Stakheyeva, M. N. (2022) · Siberian Journal of Oncology · doi:10.21294/1814-4861-2022-21-4-124-136 · Cited by 23
Simón‐Fuentes, M., Herrero, C., Acero-Riaguas, L., Nieto, C., Lasala, F., Labiod, N., Luczkowiak, J., Alonso, B., Delgado, R. B., Colmenares, M., et al. (2023) · Journal of Innate Immunity · doi:10.1159/000530249 · Cited by 21
The Roles and Targeting of Tumor-Associated Macrophages
Li, Y., Wang, R., & Gao, Q. (2023) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2809207 · Cited by 20
Kusakabe, Y., Uchida, K., Hiruma, T., Suzuki, Y., Totsu, T., Suzuki, T., Carey, B. C., Yamada, Y., & Trapnell, B. C. (2014) · Journal of Immunological Methods · doi:10.1016/j.jim.2014.07.009 · Cited by 20
Nascimento, C. R., Freire-de-Lima, C. G., Oliveira, A. D. S., Rumjanek, F. D., & Rumjanek, V. M. (2010) · Immunobiology · doi:10.1016/j.imbio.2010.07.004 · Cited by 20
Li, P., Yuan, S., & Galipeau, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069405 · Cited by 20
Zheng, Q., Li, X., Cheng, X., Cui, T., Zhuo, Y., Ma, W., Zhao, X., Zhao, P., Liu, X., & Feng, W. (2017) · Tumor Biology · doi:10.1177/1010428317692232 · Cited by 20
Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors
Ramachandran, S. A., Jadhavar, P. S., Miglani, S. K., Singh, M. P., Kalane, D. P., Agarwal, A. K., Sathe, B. D., Mukherjee, K., Gupta, A., Haldar, S., et al. (2017) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2017.03.064 · Cited by 20
Granulocyte-macrophage colony-stimulating factor as a mediator of autoimmunity in multiple sclerosis
Kostić, M. S., Živković, N., Cvetanović, A., & Stojanović, I. R. (2018) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2018.07.002 · Cited by 21
Applying Serum Cytokine Levels to Predict Pain Severity in Cancer Patients
Fazzari, J., Sidhu, J., Motkur, S., Inman, M. D., Buckley, N., Clemons, M. J., Vandermeer, L., & Singh, G. (2020) · Journal of Pain Research · doi:10.2147/jpr.s227175 · Cited by 20
The human G protein‐coupled ATP receptor P2Y 11 is a target for anti‐inflammatory strategies
Gruenbacher, G., Gander, H., Dobler, G., Rahm, A., Klaver, D., & Thurnher, M. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15379 · Cited by 20
Hashimoto, M., Nasser, H., Chihara, T., & Suzu, S. (2014) · Cell Death and Disease · doi:10.1038/cddis.2014.233 · Cited by 20
Patterson, B. K., Yogendra, R., Francisco, E. B., Guevara-Coto, J. A., Long, E., Pise, A., Osgood, E. D., Bream, J., Kreimer, M., Jeffers, D., et al. (2025) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2025.2494934 · Cited by 26
Estrogen-induced immune changes within the normal mammary gland
Tower, H., Dall, G., Davey, A. S., Stewart, M. K., Lanteri, P., Ruppert, M., Lambouras, M., Nasir, I., Yeow, S., Darcy, P. K., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-21871-4 · Cited by 20
CIS controls the functional polarization of GM-CSF-derived macrophages
Zhang, S., Rautela, J., Bediaga, N. G., Kolesnik, T. B., You, Y., Nie, J., Dagley, L. F., Bedő, J., Wang, H., Sun, L. J., et al. (2022) · Cellular and Molecular Immunology · doi:10.1038/s41423-022-00957-z · Cited by 20
Macrophages drive KSHV B cell latency
Szymula, A., Samayoa-Reyes, G., Ogolla, S., Liu, B., Li, S., George, A., Sciver, N. V., Rochford, R. A., Simas, J. P., & Kaye, K. M. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112767 · Cited by 19
The exploration of neuroinflammatory mechanism by which CRHR2 deficiency induced anxiety disorder
Deng, S., Guo, A., Huang, Z., Guan, K., Zhu, Y., Chan, C., Gui, J., Song, C., & Li, X. (2023) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110844 · Cited by 21
Mavrilimumab: an evidence based review of its potential in the treatment of rheumatoid arthritis
Franco, M. D., Gerardi, M. C., Conti, F., & Lucchino, B. (2014) · Core evidence · doi:10.2147/ce.s39770 · Cited by 19
Spotlight on mavrilimumab for the treatment of rheumatoid arthritis: evidence to date
Crotti, C., Raimondo, M. G., Becciolini, A., Biggioggero, M., & Favalli, E. G. (2017) · Drug Design Development and Therapy · doi:10.2147/dddt.s104233 · Cited by 19
Ruben, J. M., García-Romo, G. S., Breman, E., van der Kooij, S. W., Redeker, A., Arens, R., & van Kooten, C. (2017) · Kidney International · doi:10.1016/j.kint.2017.08.006 · Cited by 19
Martins, E. S., César-Neto, J. B., Albuquerque‐Souza, E., Rebeis, E. S., Holzhausen, M., Pannuti, C. M., Mayer, M. P. A., & Saraiva, L. M. (2019) · Cytokine · doi:10.1016/j.cyto.2018.12.019 · Cited by 20
Khan, W. A. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.68834 · Cited by 19
Tateyama, H., Murase, Y., Higuchi, H., Inasaka, Y., Kaneoka, H., Iijima, S., & Nishijima, K. (2019) · Immunology · doi:10.1111/imm.13121 · Cited by 19
Lin, Y., Jin, L., Tong, W. M., Leung, Y. Y., Gu, M., & Yang, Y. (2021) · Journal of Periodontal Research · doi:10.1111/jre.12864 · Cited by 19
Regulation of B cell functions by S-nitrosoglutathione in the EAE model
Kim, J., Islam, S. M. T., Qiao, F., Singh, A. K., Khan, M., Won, J., & Singh, I. (2021) · Redox Biology · doi:10.1016/j.redox.2021.102053 · Cited by 19
Gerber, J. P., Russ, J., Chandrasekar, V., Offermann, N., Lee, H., Spear, S., Guzzi, N., Maida, S., Pattabiraman, S., Zhang, R., et al. (2021) · Nature Cell Biology · doi:10.1038/s41556-021-00774-y · Cited by 21
Jannasch, M., Gaetzner, S., Groeber, F., Weigel, T., Walles, H., Schmitz, T., & Hansmann, J. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.03.029 · Cited by 19
Macrophage Signaling Pathways: A Novel Target in Renal Disease
Ma, F. Y., Ikezumi, Y., & Nikolic‐Paterson, D. J. (2010) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2010.03.008 · Cited by 19
Malbon, A. J., Michalopoulou, E., Meli, M. L., Barker, E., Tasker, S., Baptiste, K. E., & Kipar, A. (2020) · Pathogens · doi:10.3390/pathogens9110893 · Cited by 20
Xiong, L., Cao, J., Yang, X., Chen, S., Wu, M., Wang, C., Xu, H., Chen, Y., Zhang, R., Hu, X., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.965273 · Cited by 18
Simón‐Fuentes, M., Ríos, I., Herrero, C., Lasala, F., Labiod, N., Luczkowiak, J., Roy‐Vallejo, E., de Córdoba‐Oñate, S. F., Delgado‐Wicke, P., Bustos, M., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.172862 · Cited by 18
Coschi, C. H., & Juergens, R. A. (2023) · Current Oncology · doi:10.3390/curroncol31010001 · Cited by 23
Macrophage re-programming by JAK inhibitors relies on MAFB
López-Navarro, B., Simón‐Fuentes, M., Ríos, I., Schiaffino, M. T., Sánchez, A., Torres‐Torresano, M., Nieto‐Valle, A., Castrejón, I., & Puig‐Kröger, A. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05196-1 · Cited by 20
Sun, J., Peterson, E., Chen, X., & Wang, J. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114092 · Cited by 26
Repeat element-driven activation of proto-oncogenes in human malignancies
Lamprecht, B., Bonifer, C., & Mathas, S. (2010) · Cell Cycle · doi:10.4161/cc.9.21.13682 · Cited by 18
Inhibitory mechanism of Korean Red Ginseng on GM-CSF expression in UVB-irradiated keratinocytes
Chung, I., Lee, J., Park, Y. S., Lim, Y., Chang, D. H., Park, J., & Hwang, J. S. (2015) · Journal of Ginseng Research · doi:10.1016/j.jgr.2015.03.001 · Cited by 18
Chalouhi, N., Theofanis, T. N., Starke, R. M., Zanaty, M., Jabbour, P. M., Dooley, S. A., & Hasan, D. M. (2014) · DNA and Cell Biology · doi:10.1089/dna.2014.2618 · Cited by 18
Imaging of Tumor-Associated Macrophages in a Transgenic Mouse Model of Orthotopic Ovarian Cancer
He, H., Chiu, A. C., Kanada, M., Schaar, B. T., Krishnan, V., Contag, C. H., & Dorigo, O. (2017) · Molecular Imaging and Biology · doi:10.1007/s11307-017-1061-2 · Cited by 18
Mathematical Analysis of Cytokine-Induced Differentiation of Granulocyte-Monocyte Progenitor Cells
Weston, B. R., Li, L., & Tyson, J. J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02048 · Cited by 18
The Current Status of Granulocyte-Colony Stimulating Factor to Treat Acute-on-Chronic Liver Failure
Engelmann, C., Martino, V. D., Kerbert, A. J. C., Weil, D., Aehling, N., Herber, A., Thévenot, T., & Berg, T. (2021) · Seminars in Liver Disease · doi:10.1055/s-0041-1723034 · Cited by 18
The influence of M-CSF on fracture healing in a mouse model
Starlinger, J., Sarahrudi, K., Kecht, M., Koerbler, F., Pietschmann, P., & Aharinejad, S. (2021) · Scientific Reports · doi:10.1038/s41598-021-01673-w · Cited by 18
STAT3-Activated GM-CSFRα Translocates to the Nucleus and Protects CLL Cells from Apoptosis
Li, P., Harris, D., Liu, Z., Rozovski, U., Ferrajoli, A., Wang, Y., Bueso-Ramos, C., Hazan‐Halevy, I., Grgurević, S., Wierda, W. G., et al. (2014) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-13-0652-t · Cited by 18
Zhang, L., Pavicic, P. G., Datta, S., Song, Q., Xu, X., Wei, W., Su, F., Rayman, P. A., Zhao, C., & Hamilton, T. A. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01390 · Cited by 19
Janke, M., Peine, C., Nass, A., Morawietz, L., Hamann, A., & Scheffold, A. (2010) · European Journal of Immunology · doi:10.1002/eji.200939487 · Cited by 18
Gene expression profiling in anti-CD11d mAb-treated spinal cord-injured rats
Gris, P., Tighe, A., Thawer, S. G., Hemphill, A. F., Oatway, M. A., Weaver, L. C., Dekaban, G. A., & Brown, A. M. (2009) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2009.02.002 · Cited by 18
St‐Onge, M., Dumas, A., Michaud, A., Laflamme, C., Dussault, A., & Pouliot, M. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004902 · Cited by 18
Ehlers, G., Tödtmann, A. M., Holsten, L., Willers, M., Heckmann, J., Schöning, J., Richter, M., Heinemann, A. S., Pirr, S. M., Heinz, A., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-57357-w · Cited by 20
Exercise Delays Brain Ageing Through Muscle‐Brain Crosstalk
Pourteymour, S., Majhi, R. K., Norheim, F., & Drevon, C. A. (2025) · Cell Proliferation · doi:10.1111/cpr.70026 · Cited by 21
Korniotis, S., Saichi, M., Trichot, C., Hoffmann, C., Amblard, E., Viguier, A., Grondin, S., Noël, F., Mattoo, H., & Soumelis, V. (2022) · Journal of Cell Science · doi:10.1242/jcs.260298 · Cited by 17
The Vaginal Immunoproteome for the Prediction of Spontaneous Preterm Birth
Shaffer, Z., Romero, R. J., Tarca, A. L., Galaz, J., Arenas‐Hernandez, M., Gudicha, D. W., Chaiworapongsa, T., Jung, E., Suksai, M., Gotsch, F., et al. (2022) · eLife · doi:10.7554/elife.90943 · Cited by 19
Hassan, R., Suzu, S., Hiyoshi, M., Takahashi‐Makise, N., Ueno, T., Agatsuma, T., Akari, H., Komano, J. A., Takebe, Y., Motoyoshi, K., et al. (2009) · Journal of Cellular Physiology · doi:10.1002/jcp.21878 · Cited by 17
GM-CSF alters dendritic cells in autoimmune diseases
Li, B., Ye, Q.-L., Xu, W., Li, J., Ye, D., & Xu, Y. (2013) · Autoimmunity · doi:10.3109/08916934.2013.803533 · Cited by 16
GM-CSF and the role of myeloid regulatory cells in the pathogenesis and treatment of Crohn’s disease
Däbritz, J. (2015) · Molecular and Cellular Pediatrics · doi:10.1186/s40348-015-0024-4 · Cited by 17
Eylenstein, R., Weinfurtner, D., Härtle, S., Strohner, R., Böttcher, J., Augustin, M. A., Ostendorp, R., & Steidl, S. (2015) · mAbs · doi:10.1080/19420862.2015.1099774 · Cited by 17
Sei, J. J., Waters, R. A., Kenney, M., Barlow, J., & Golde, W. T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0152192 · Cited by 17
Berkovich, R., Bakshi, R., Amezcua, L., Axtell, R. C., Cen, S., Tauhid, S., Neema, M., & Steinman, L. (2016) · Therapeutic Advances in Neurological Disorders · doi:10.1177/1756285616670060 · Cited by 17
CaCO3-Encapsulated Au Nanoparticles Modulate Macrophages toward M1-like Phenotype
Yang, S., Zhang, Y., Lü, S., Yang, L., Yu, S., & Yang, H. (2021) · ACS Applied Bio Materials · doi:10.1021/acsabm.0c01608 · Cited by 17
Guo, J., Zhang, B., Xiong, Y., Kang, T., Han, Y., Xu, Y., Zhao, W., Yü, P., Zhang, L., Song, C., et al. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.114580 · Cited by 17
Hanaoka, R., Ueno, Y., Tanaka, S., Nagai, K., Onitake, T., Yoshioka, K., & Chayama, K. (2011) · Scandinavian Journal of Immunology · doi:10.1111/j.1365-3083.2011.02601.x · Cited by 18
van de Laar, L., van den Bosch, A., Wierenga, A. T. J., Janssen, H. L. A., Coffer, P. J., & Woltman, A. M. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1003977 · Cited by 16
Function of hematopoiesis and bone marrow niche in inflammation and non-hematopoietic diseases
Wang, Y., Deng, Z., Li, Y.-Y., Bai, K., Ma, J., Liu, Y., & Chen, Q. (2025) · Life Medicine · doi:10.1093/lifemedi/lnaf015 · Cited by 19
Vikberg, S., Lindau, R. H., Solders, M., Raffetseder, J., Budhwar, S., Ernerudh, J., Tiblad, E., & Kaipe, H. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1129261 · Cited by 16
Li, C., Lin, W.-C., Moonmanee, T., Chan, J. P., & Wang, C. (2024) · Animals · doi:10.3390/ani14071079 · Cited by 16
Hamada, K., Yoshihara, C., Ito, T., Tani, K., Tagawa, M., Sakuragawa, N., Itoh, H., & Koyama, Y. (2012) · The Journal of Gene Medicine · doi:10.1002/jgm.1647 · Cited by 16
Ecker, J., Liebisch, G., Grandl, M., & Schmitz, G. (2010) · Immunobiology · doi:10.1016/j.imbio.2010.05.016 · Cited by 16
Novel monoclonal antibodies for therapy of multiple sclerosis
Knier, B., Hemmer, B., & Korn, T. (2014) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2014.887676 · Cited by 16
Cypher, L. R., Bielecki, T. A., Huang, L., An, W., Iseka, F., Tom, E., Storck, M. D., Hoppe, A. D., Band, V., & Band, H. (2016) · Cellular Signalling · doi:10.1016/j.cellsig.2016.05.013 · Cited by 16
Shen, Z. T., & Sigalov, A. B. (2016) · Scientific Reports · doi:10.1038/srep28672 · Cited by 16
Karagianni, A. E., Kurian, D., Cillán‐García, E., Eaton, S. L., Wishart, T. M., & Pirie, R. S. (2022) · Scientific Reports · doi:10.1038/s41598-021-04137-3 · Cited by 16
Metadata
- Authors
- Hamilton, J. A.
- Affiliations
- The Royal Melbourne Hospital (AU)
- Corresponding author
- Hamilton, John A.
- ORCID
- Hamilton, John A.
- Venue
- Nature reviews. Immunology
- Published
- 2008-07
- Volume
- 8
- Issue
- 7
- Pages
- 533-544
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2063680739
- Cited by
- 1,305
- References
- 141
- Citations by year
- 2026: 33 · 2025: 45 · 2024: 49 · 2023: 57 · 2022: 81 · 2021: 83 · 2020: 75 · 2019: 63 · 2018: 82 · 2017: 94 · 2016: 85 · 2015: 92 · 2014: 94 · 2013: 71 · 2012: 89
- FWCI
- 6.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Immunology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Cytokine Signaling Pathways and Interactions
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Keywords
- colony-stimulating factors, inflammation, autoimmunity, granulocyte colony-stimulating factor, macrophage colony-stimulating factor, myeloid cells, hematopoietic growth factors
- MeSH terms
- Animals, Arthritis, Colony-Stimulating Factors, Encephalomyelitis, Autoimmune, Experimental, Humans, Inflammation, Lung Diseases, Neoplasms, Nephritis, Autoimmunity, Receptors, Colony-Stimulating Factor, Atherosclerosis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
