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CSF-1 receptor signalling is governed by pre-requisite EHD1 mediated receptor display on the macrophage cell surface
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EHD1 is required for the basal surface expression of the RTK CSF1 receptor in wild-type and EHD1-null bone marrow-derived macrophages.
“Recently, using wild-type and EHD1-null bone marrow-derived macrophages, we found that EHD1 is required for the basal surface expression of the RTK colony-stimulating factor 1 (CSF1) receptor (41).”
From EHD1 and RUSC2 Control Basal Epidermal Growth Factor Receptor Cell Surface Expression and Recycling (2020) · cites this paper as [41]
EHD1 plays a key role in the surface expression of CSF1R on primary macrophages.
“Consistent with a broader role of EHD1 in RTK trafficking, we have recently found that EHD1 also plays a key role in the surface expression of the CSF1R, an RTK, on primary macrophages (41).”
From EHD1 and RUSC2 Control Basal Epidermal Growth Factor Receptor Cell Surface Expression and Recycling (2020) · cites this paper as [41]
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Cites
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EHD1 and RUSC2 Control Basal Epidermal Growth Factor Receptor Cell Surface Expression and Recycling
Tom, E. C., Mushtaq, I., Mohapatra, B. C., Luan, H., Bhat, A. M., Zutshi, N., Chakraborty, S., Islam, N., Arya, P., Bielecki, T. A., et al. (2020) · Molecular and Cellular Biology · doi:10.1128/mcb.00434-19 · Cited by 13
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Metadata
- Authors
- Cypher, L. R., Bielecki, T. A., Huang, L., An, W., Iseka, F., Tom, E., Storck, M. D., Hoppe, A. D., Band, V., & Band, H.
- Venue
- Cellular Signalling
- Publisher
- Elsevier BV
- Published
- 2016-09
- Volume
- 28
- Issue
- 9
- Pages
- 1325-1335
- ISSN
- 0898-6568
- PMC
- PMC5045265
- Cited by
- 16
- References
- 7
- Language
- en
- Update notices
- erratum (2016-12-01)
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (am, 287 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Funders
- NIH (CA105489, CA87986, CA99163, CA116552, CA96844, CA144027)
- Department of Defense (W81XWH-07-1-0351, W81XWH-11-1-0171)
- NE DHHS LB-506 (2014-01)
- LB606 (18123-Y3)
- NIGMS of the NIH (P30 GM1063)
- NCI Cancer Center Support (P30CA036727)
- Pamela Buffett Cancer Center
- Nebraska Research Initiative
- NCI Cancer Biology Training Grant (T32CA009476)
- UNMC
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