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Cited by 360

The DOI matches its Crossref record; 139 of the 139 references it cites were found in a registry or an index.

MicroRNA-mediated regulation of T helper cell differentiation and plasticity

Open access
Baumjohann, Dirk, Ansel, K. Mark·2013·Nature Reviews Immunology

Abstract

CD4+ T helper (TH) cells regulate appropriate cellular and humoral immune responses to a wide range of pathogens and are central to the success of vaccines. However, their dysregulation can cause allergies and autoimmune diseases. The CD4+ T cell population is characterized not only by a range of distinct cell subsets, such as TH1, TH2 and TH17 cells, regulatory T cells and T follicular helper cells — each with specific functions and gene expression programmes — but also by plasticity between the different TH cell subsets. In this Review, we discuss recent advances and emerging ideas about how microRNAs — small endogenously expressed oligonucleotides that modulate gene expression — are involved in the regulatory networks that determine TH cell fate decisions and that regulate their effector functions.

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Metadata

Authors
Baumjohann, D., & Ansel, K. M.
Venue
Nature Reviews Immunology
Published
2013-08-02
Volume
13
Issue
9
Pages
666-678
ISSN
  • 1474-1733 (ISSN-L)
  • 1474-1741
OpenAlex
W1987455407
Cited by
360
References
139
FWCI
2.32
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: MicroRNA-mediated regulation of T helper cell differentiation and plasticity. https://app.cochat.ai/papers/10.1038/nri3494
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Baumjohann, D., & Ansel, K. M. (2013). MicroRNA-mediated regulation of T helper cell differentiation and plasticity. Nature Reviews Immunology. https://doi.org/10.1038/nri3494

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