Apoptotic cell clearance: basic biology and therapeutic potential

Inflammation and cancer

Coussens, L. M., & Werb, Z. (2002) · Nature · doi:10.1038/nature01322 · Cited by 15,111

Neutrophil Extracellular Traps Kill Bacteria

Brinkmann, V., Reichard, U., Goosmann, C., Fauler, B., Uhlemann, Y., Weiss, D. S., Weinrauch, Y., & Zychlinsky, A. (2004) · Science · doi:10.1126/science.1092385 · Cited by 10,268

Tolerance, Danger, and the Extended Family

Matzinger, P. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.005015 · Cited by 4,848

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

Fadok, V. A., Voelker, D. R., Campbell, P. A., Cohen, J., Bratton, D. L., & Henson, P. M. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.148.7.2207 · Cited by 3,321

Immunogenic Cell Death in Cancer Therapy

Kroemer, G., Galluzzi, L., Kepp, O., & Zitvogel, L. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-100008 · Cited by 3,303

Pyroptosis: host cell death and inflammation

Bergsbaken, T., Fink, S. L., & Cookson, B. T. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2070 · Cited by 3,288

Immunogenic cell death and DAMPs in cancer therapy

Krysko, D. V., Garg, A. D., Kaczmarek, A., Krysko, O., Agostinis, P., & Vandenabeele, P. (2012) · Nature Reviews Cancer · doi:10.1038/nrc3380 · Cited by 3,223

Calreticulin exposure dictates the immunogenicity of cancer cell death

Obeid, M., Tesniere, A., Ghiringhelli, F., Fimia, G. M., Apetoh, L., Perfettini, J.-L., Castedo, M., Mignot, G., Panaretakis, T., Casares, N., et al. (2007) · Nature Medicine · doi:10.1038/nm1523 · Cited by 3,216

Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Apetoh, L., Ghiringhelli, F., Tesniere, A., Obeid, M., Ortiz, C., Criollo, A., Mignot, G., Maiuri, M. C., Ullrich, E., Saulnier, P., et al. (2007) · Nature Medicine · doi:10.1038/nm1622 · Cited by 3,056

DAMPs, PAMPs and alarmins: all we need to know about danger

Bianchi, M. E. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0306164 · Cited by 2,794

Programmed Necrosis and Disease:We interrupt your regular programming to bring you necroinflammation

Kim, E. H., Wong, S., & Martinez, J. (2018) · Cell Death and Differentiation · doi:10.1038/s41418-018-0179-3 · Cited by 181

Human neutrophils in auto-immunity

Thiéblemont, N., Wright, H. L., Edwards, S. W., & Witko‐Sarsat, V. (2016) · Seminars in Immunology · doi:10.1016/j.smim.2016.03.004 · Cited by 179

The matricellular protein CCN1 mediates neutrophil efferocytosis in cutaneous wound healing

Jun, J.-I., Kim, K.-H., & Lau, L. F. (2015) · Nature Communications · doi:10.1038/ncomms8386 · Cited by 173

Macrophages and skeletal health

Michalski, M. N., & McCauley, L. K. (2017) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2017.02.017 · Cited by 171

Formation and Maturation of the Phagosome: A Key Mechanism in Innate Immunity against Intracellular Bacterial Infection

Lee, H.-J., Woo, Y., Hahn, T., Jung, Y. M., & Jung, Y. (2020) · Microorganisms · doi:10.3390/microorganisms8091298 · Cited by 181

CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production

Novais, F. O., Carvalho, A. M., Clark, M. L., Carvalho, L. P., Beiting, D. P., Brodsky, I. E., Carvalho, E. M., & Scott, P. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006196 · Cited by 171

Extracellular vesicles as modulators of wound healing

Cabral, J., Ryan, A. E., Griffin, M. D., & Ritter, T. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.01.018 · Cited by 171

Regulation and Functions of 15-Lipoxygenases in Human Macrophages

Snodgrass, R. G., & Brüne, B. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00719 · Cited by 167

Cystic Fibrosis Lung Immunity: The Role of the Macrophage

Bruscia, E. M., & Bonfield, T. L. (2016) · Journal of Innate Immunity · doi:10.1159/000446825 · Cited by 168

Isolation and analysis methods of extracellular vesicles (EVs)

Zhao, Z., Wijerathne, H., Godwin, A. K., & Soper, S. A. (2021) · Extracellular Vesicles and Circulating Nucleic Acids · doi:10.20517/evcna.2021.07 · Cited by 169

Single-Vesicle Assays Using Liposomes and Cell-Derived Vesicles: From Modeling Complex Membrane Processes to Synthetic Biology and Biomedical Applications

Pick, H. M., Alves, A. C., & Vogel, H. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00777 · Cited by 160

Aged marrow macrophages expand platelet-biased hematopoietic stem cells via interleukin-1B

Frisch, B. J., Hoffman, C. M., Latchney, S. E., LaMere, M. W., Myers, J., Ashton, J., Li, A. J., Saunders, J., Palis, J., Perkins, A. S., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.124213 · Cited by 160

Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes

Zakharov, P. N., Hu, H., Wan, X., & Unanue, E. R. (2020) · Journal of Experimental Medicine · doi:10.1084/jem.20192362 · Cited by 149

Macrophage: Key player in the pathogenesis of autoimmune diseases

Yang, S. C., Zhao, M., & Jia, S. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1080310 · Cited by 165

IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation

Satyanarayanan, S. K., Kebir, D. E., Soboh, S., Butenko, S., Sekheri, M., Saadi, J., Peled, N., Assi, S., Othman, A., Schif‐Zuck, S., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-10903-9 · Cited by 165

Keratinocyte death by ferroptosis initiates skin inflammation after UVB exposure

Vats, K., Kruglov, O., Mizes, A., Самович, С. Н., Amoscato, A. A., Tyurin, V. A., Tyurina, Y. Y., Kagan, V. E., & Bunimovich, Y. L. (2021) · Redox Biology · doi:10.1016/j.redox.2021.102143 · Cited by 161

Efferocytosis in the tumor microenvironment

Werfel, T. A., & Cook, R. S. (2018) · Seminars in Immunopathology · doi:10.1007/s00281-018-0698-5 · Cited by 156

Neutrophil and remnant clearance in immunity and inflammation

Singhal, A., & Kumar, S. (2021) · Immunology · doi:10.1111/imm.13423 · Cited by 160

Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool

Mesa, K. R., Rompolas, P., Zito, G., Myung, P. S., Sun, T. Y., Brown, S., Gonzalez, D. G., Blagoev, K. B., Haberman, A. M., & Greco, V. (2015) · Nature · doi:10.1038/nature14306 · Cited by 161

Scalable Production of Extracellular Vesicles and Its Therapeutic Values: A Review

Ng, C. Y., Kee, L. T., Al-Masawa, M. E., Lee, Q. H., Subramaniam, T., Kok, D., Ng, M. H., & Law, J. X. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147986 · Cited by 157

Harnessing anti‐tumor and tumor‐tropism functions of macrophages via nanotechnology for tumor immunotherapy

Zheng, Y., Han, Y., Sun, Q., & Li, Z. (2022) · Exploration · doi:10.1002/exp.20210166 · Cited by 151

Determining the contents and cell origins of apoptotic bodies by flow cytometry

Jiang, L., Paone, S., Caruso, S., Atkin‐Smith, G. K., Phan, T. K., Hulett, M. D., & Poon, I. K. H. (2017) · Scientific Reports · doi:10.1038/s41598-017-14305-z · Cited by 149

Lipids and flaviviruses, present and future perspectives for the control of dengue, Zika, and West Nile viruses

Martín-Acebes, M. A., Vázquez-Calvo, Á., & Sáiz, J. (2016) · Progress in Lipid Research · doi:10.1016/j.plipres.2016.09.005 · Cited by 150

Role of Macrophages in Wound HealingPreprint

Willenborg, S., Injarabian, L., & Eming, S. A. (2022) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a041216 · Cited by 150

Macrophage‐Mediated Tumor Cell Phagocytosis: Opportunity for Nanomedicine Intervention

Zhou, X., Liu, X., & Huang, L. (2020) · Advanced Functional Materials · doi:10.1002/adfm.202006220 · Cited by 147

Modulating the immune system through nanotechnology

Dacoba, T. G., Ana, O., Torres, D., Crecente‐Campo, J., & Alonso, M. J. (2017) · Seminars in Immunology · doi:10.1016/j.smim.2017.09.007 · Cited by 150

Immunity in Molluscs: Recognition and Effector Mechanisms, with a Focus on Bivalvia

Gerdol, M., Marta Gómez-chiarri, G., Castillo, M. G., Figueras, A. J., Fiorito, G., Moreira, R., Novoa, B., Pallavicini, A., Ponte, G., Roumbedakis, K., et al. (2018) · Springer eBooks · doi:10.1007/978-3-319-76768-0_11 · Cited by 147

Co-localized delivery of nanomedicine and nanovaccine augments the postoperative cancer immunotherapy by amplifying T-cell responses

Liu, X., Feng, Z., Wang, C., Su, Q., Song, H., Zhang, C., Huang, P., Liang, X., Dong, A., Kong, D., et al. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119649 · Cited by 148

PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines

Yoon, Y.-S., Kim, S.-Y., Kim, M.-J., Lim, J.-H., Cho, M.-S., & Kang, J. L. (2015) · Mucosal Immunology · doi:10.1038/mi.2014.130 · Cited by 145

A quantized mechanism for activation of pannexin channels

Chiu, Y., Jin, X., Medina, C. B., Leonhardt, S. A., Kiessling, V., Bennett, B. C., Shu, S., Tamm, L. K., Yeager, M. J., Ravichandran, K. S., et al. (2017) · Nature Communications · doi:10.1038/ncomms14324 · Cited by 144

Therapeutic angiogenesis using stem cell-derived extracellular vesicles: an emerging approach for treatment of ischemic diseases

Bian, X., Ma, K., Zhang, C., & Fu, X. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1276-z · Cited by 145

Integrin signaling in atherosclerosis

Finney, A. C., Stokes, K. Y., Pattillo, C. B., & Orr, A. W. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2490-4 · Cited by 142

Molecular Communication of a Dying Neuron in Stroke

Puig, B., Brenna, S., & Magnus, T. U. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092834 · Cited by 146

Mathematical Modelling of Molecular Pathways Enabling Tumour Cell Invasion and Migration

Cohen, D., Martignetti, L., Robine, S., Barillot, E., Zinovyev, A. Y., & Calzone, L. (2015) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1004571 · Cited by 141

Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1

Sugimoto, M. A., Ribeiro, A. L. C., Costa, B. R. C., Vago, J. P., Lima, K. M., Carneiro, F. S., Ortiz, M. M. O., Negreiros-Lima, G. L., Carmo, A. A. F., Rocha, R. M., et al. (2017) · Blood · doi:10.1182/blood-2016-09-742825 · Cited by 143

Rheumatoid arthritis–celiac disease relationship: Joints get that gut feeling

Lerner, A., & Matthias, T. (2015) · Autoimmunity Reviews · doi:10.1016/j.autrev.2015.07.007 · Cited by 139

The induction and consequences of Influenza A virus-induced cell death

Atkin‐Smith, G. K., Duan, M., Chen, W., & Poon, I. K. H. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-1035-6 · Cited by 141

Programmed cell death pathways in hearing loss: A review of apoptosis, autophagy and programmed necrosis

Wu, J., Ye, J., Kong, W., Zhang, S., & Zheng, Y. (2020) · Cell Proliferation · doi:10.1111/cpr.12915 · Cited by 137

Unpacking extracellular vesicles: RNA cargo loading and function

Dellar, E. R., Hill, C., Melling, G. E., Carter, D. R. F., & Baena-López, L. A. (2022) · Journal of Extracellular Biology · doi:10.1002/jex2.40 · Cited by 145

Regulation of Csf1r and Bcl6 in Macrophages Mediates the Stage-Specific Effects of MicroRNA-155 on Atherosclerosis

Wei, Y., Zhu, M., Corbalán-Campos, J., Heyll, K., Weber, C., & Schober, A. (2015) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.304723 · Cited by 135

Characterisation of adipocyte‐derived extracellular vesicles released pre‐ and post‐adipogenesis

Connolly, K. D., Guschina, I. A., Yeung, V., Clayton, A., Draman, M. S., von Ruhland, C., Ludgate, M. E., James, P. E., & Rees, A. (2015) · Journal of Extracellular Vesicles · doi:10.3402/jev.v4.29159 · Cited by 134

Immunogenic versus tolerogenic phagocytosis during anticancer therapy: mechanisms and clinical translation

Garg, A. D., Romano, E., Rufo, N., & Agostinis, P. (2016) · Cell Death and Differentiation · doi:10.1038/cdd.2016.5 · Cited by 133

Myeloid Slc2a1 -Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1

Freemerman, A. J., Zhao, L., Pingili, A. K., Teng, B., Cozzo, A. J., Fuller, A. M., Johnson, A., Milner, J. J., Lim, M. F., Galanko, J. A., et al. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1800002 · Cited by 132

Targeting the Oncogene KRAS Mutant Pancreatic Cancer by Synergistic Blocking of Lysosomal Acidification and Rapid Drug Release

Kong, C., Li, Y., Liu, Z., Ye, J., Wang, Z., Zhang, L., Kong, W., Liu, H., Liu, C., Pang, H., et al. (2019) · ACS Nano · doi:10.1021/acsnano.8b08246 · Cited by 127

New Advances in Targeting the Resolution of Inflammation: Implications for Specialized Pro-Resolving Mediator GPCR Drug Discovery

Park, J., Langmead, C. J., & Riddy, D. (2020) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.9b00075 · Cited by 137

The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung

Fujimori, T., Grabiec, A. M., Kaur, M., Bell, T. J., Fujino, N., Cook, P. C., Svedberg, F. R., MacDonald, A. S., Maciewicz, R. A., Singh, D., et al. (2015) · Mucosal Immunology · doi:10.1038/mi.2014.129 · Cited by 132

Programmed Cell Death and Inflammation: Winter Is Coming

Kolb, J. P., Oguin, T. H., Oberst, A., & Martinez, J. (2017) · Trends in Immunology · doi:10.1016/j.it.2017.06.009 · Cited by 136

Mechanisms of Regulated Cell Death: Current Perspectives

Santagostino, S. F., Assenmacher, C., Tarrant, J. C., Adedeji, A. O., & Radaelli, E. (2021) · Veterinary Pathology · doi:10.1177/03009858211005537 · Cited by 137

Macrophage Apoptosis and Necrotic Core Development in Atherosclerosis: A Rapidly Advancing Field with Clinical Relevance to Imaging and Therapy

González, L., & Trigatti, B. L. (2016) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2016.12.010 · Cited by 136

Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation

Marwick, J. A., Mills, R., Kay, O., Michail, K., Stephen, J., Rossi, A. G., Dransfield, I., & Hirani, N. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0710-y · Cited by 136

Macrophages reprogram after ischemic stroke and promote efferocytosis and inflammation resolution in the mouse brain

Zhang, W., Zhao, J., Wang, R., Jiang, M., Ye, Q., Smith, A. D., Chen, J., & Shi, Y. (2019) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13256 · Cited by 132

Cancer treatment by magneto-mechanical effect of particles, a review

Naud, C., Thébault, C. J., Carrière, M., Hou, Y., Morel, R., Berger, F. R., Diény, B., & Joisten, H. (2020) · Nanoscale Advances · doi:10.1039/d0na00187b · Cited by 129

Clinical Tracking of Cell Transfer and Cell Transplantation: Trials and Tribulations

Bulte, J. W. M., & Daldrup-Link, H. E. (2018) · Radiology · doi:10.1148/radiol.2018180449 · Cited by 129

Monogenic lupus: Dissecting heterogeneity

Omarjee, O., Picard, C., Frachette, C., Moreews, M., Rieux‐Laucat, F., Soulas-Sprauel, P., Viel, S., Lega, J., Bader‐Meunier, B., Walzer, T., et al. (2019) · Autoimmunity Reviews · doi:10.1016/j.autrev.2019.102361 · Cited by 135

A long-awaited merger of the pathways mediating host defence and programmed cell death

Blander, J. M. (2014) · Nature reviews. Immunology · doi:10.1038/nri3720 · Cited by 127

Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo

Lee, C. S., Penberthy, K. K., Wheeler, K. M., Juncadella, I. J., Vandenabeele, P., Lysiak, J. J., & Ravichandran, K. S. (2016) · Immunity · doi:10.1016/j.immuni.2016.02.005 · Cited by 131

Regulation of C-reactive protein conformation in inflammation

Yao, Z., Zhang, Y., & Wu, H. (2019) · Inflammation Research · doi:10.1007/s00011-019-01269-1 · Cited by 128

Proceedings of the 35th European Peptide Symposium

Bonnet, D. (2018) · doi:10.17952/35eps · Cited by 124

Facile synthesis of highly uniform selenium nanoparticles using glucose as the reductant and surface decorator to induce cancer cell apoptosis

Nie, T., Wu, H., Wong, K., & Chen, T. (2016) · Journal of Materials Chemistry B · doi:10.1039/c5tb02710a · Cited by 127

The Role of Efferocytosis in Autoimmune Diseases

Abdolmaleki, F., Farahani, N., Hayat, S. M. G., Pirro, M., Bianconi, V., Barreto, G. E., & Sahebkar, A. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01645 · Cited by 129

Immune Response of Amebiasis and Immune Evasion by Entamoeba histolytica

Nakada‐Tsukui, K., & Nozaki, T. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00175 · Cited by 127

Physiology and pathology of T-cell aging

Minato, N., Hattori, M., & Hamazaki, Y. (2020) · International Immunology · doi:10.1093/intimm/dxaa006 · Cited by 124

Regulated cell death: discovery, features and implications for neurodegenerative diseases

Cui, J., Zhao, S., Li, Y., Zhang, D., Wang, B., Xie, J., & Wang, J. (2021) · Cell Communication and Signaling · doi:10.1186/s12964-021-00799-8 · Cited by 130

Tumor-associated macrophages are shaped by intratumoral high potassium via Kir2.1

Chen, S., Cui, W., Chi, Z., Xiao, Q., Hu, T., Ye, Q., Zhu, K., Yu, W., Wang, Z., Yu, C., et al. (2022) · Cell Metabolism · doi:10.1016/j.cmet.2022.08.016 · Cited by 123

Pathogen response-like recruitment and activation of neutrophils by sterile immunogenic dying cells drives neutrophil-mediated residual cell killing

Garg, A. D., Vandenberk, L., Fang, S., Fasche, T., Van Eygen, S., Maes, J., Van Woensel, M., Koks, C., Vanthillo, N., Graf, N., et al. (2017) · Cell Death & Differentiation · doi:10.1038/cdd.2017.15 · Cited by 120

IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis

Theurich, S., Tsaousidou, E., Hanßen, R., Lempradl, A. M., Mauer, J., Timper, K., Schilbach, K., Folz‐Donahue, K., Heilinger, C., Sexl, V., et al. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.05.018 · Cited by 127

The potential of circulating cell-free RNA as a cancer biomarker: challenges and opportunities

Zaporozhchenko, I. A., Ponomaryova, A. A., RYKOVA, E. Y., & Laktionov, P. P. (2018) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2018.1425143 · Cited by 123

The Role of Macrophages in the Infarcted Myocardium: Orchestrators of ECM Remodeling

O’Rourke, S. A., Dunne, A., & Monaghan, M. G. (2019) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2019.00101 · Cited by 124

Variation in human cancer cell external phosphatidylserine is regulated by flippase activity and intracellular calcium

Vallabhapurapu, S., Blanco, V., Sulaiman, M. K., Vallabhapurapu, S. L., Chu, Z., Franco, R. S., & Qi, X. (2015) · Oncotarget · doi:10.18632/oncotarget.6045 · Cited by 119

Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide

Reber, L. L., Gillis, C. M., Starkl, P. M., Jönsson, F., Sibilano, R., Marichal, T., Gaudenzio, N., Berard, M., Rogalla, S., Contag, C. H., et al. (2017) · The Journal of Experimental Medicine · doi:10.1084/jem.20161238 · Cited by 125

Recent Progress in Metal-Based Nanoparticles Mediated Photodynamic Therapy

Sun, J., Kormakov, S., Liu, Y., Huang, Y., Wu, D., & Yang, Z. (2018) · Molecules · doi:10.3390/molecules23071704 · Cited by 118

PFKFB3-Driven Macrophage Glycolytic Metabolism Is a Crucial Component of Innate Antiviral Defense

Jiang, H., Shi, H., Sun, M., Wang, Y., Meng, Q., Guo, P., Cao, Y., Chen, J., Gao, X., Li, E., et al. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1600474 · Cited by 117

Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry

Jiang, L., Tixeira, R., Caruso, S., Atkin‐Smith, G. K., Baxter, A. A., Paone, S., Hulett, M. D., & Poon, I. K. H. (2016) · Nature Protocols · doi:10.1038/nprot.2016.028 · Cited by 115

Calreticulin—Multifunctional Chaperone in Immunogenic Cell Death: Potential Significance as a Prognostic Biomarker in Ovarian Cancer Patients

Kiełbik, M., Szulc-Kiełbik, I., & Klink, M. (2021) · Cells · doi:10.3390/cells10010130 · Cited by 117

Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis

Hergott, C. A., Roche, A. M., Tamashiro, E., Clarke, T. B., Bailey, A., Laughlin, A. L., Bushman, F. D., & Weiser, J. N. (2016) · Blood · doi:10.1182/blood-2015-10-675173 · Cited by 115

The effect of ageing on the resolution of inflammation

Sendama, W. (2019) · Ageing Research Reviews · doi:10.1016/j.arr.2019.101000 · Cited by 111

Knocking ’em Dead: Pore-Forming Proteins in Immune Defense

Liu, X., & Lieberman, J. (2020) · Annual Review of Immunology · doi:10.1146/annurev-immunol-111319-023800 · Cited by 114

The STAT3–IL-10–IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury

Campana, L., Starkey Lewis, P. J., Pellicoro, A., Aucott, R. L., Man, J., O’Duibhir, E., Mok, S. E., Ferreira-Gonzalez, S., Livingstone, E., Greenhalgh, S. N., et al. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1701247 · Cited by 107

Mechanisms of Immune Tolerance in Leukemia and Lymphoma

Curran, E. K., Godfrey, J. K., & Kline, J. P. (2017) · Trends in Immunology · doi:10.1016/j.it.2017.04.004 · Cited by 108

The role of secreted factors in stem cells-mediated immune regulation

Lin, L., & Du, L. (2017) · Cellular Immunology · doi:10.1016/j.cellimm.2017.07.010 · Cited by 107

Apoptosis and its Role in Parkinson’s Disease

Erekat, N. S. (2018) · Codon Publications eBooks · doi:10.15586/codonpublications.parkinsonsdisease.2018.ch4 · Cited by 109

Extracellular Vesicles Derived From Apoptotic Cells: An Essential Link Between Death and Regeneration

Li, M., Liao, L., & Tian, W. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.573511 · Cited by 111

Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis

Millet, A., Martin, K., Bonnefoy, F., Saas, P., Mocek, J., Alkan, M., Terrier, B., Kerstein-Staehle, A., Tamassia, N., Satyanarayanan, S. K., et al. (2015) · Journal of Clinical Investigation · doi:10.1172/jci78182 · Cited by 108

Crosstalk between macrophages and cardiac cells after myocardial infarction

Jian, Y., Zhou, X. J., Shan, W., Chen, C., Ge, W., Cui, J., Yi, W., & Sun, Y. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01105-4 · Cited by 114

The role of pannexin1 in the induction and resolution of inflammation

Adamson, S. E., & Leitinger, N. (2014) · FEBS Letters · doi:10.1016/j.febslet.2014.03.009 · Cited by 103

The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer Therapy

Paolino, M., & Penninger, J. M. (2016) · Cancers · doi:10.3390/cancers8100097 · Cited by 107

Covalent Organic Framework Material Bearing Phloroglucinol Building Units as a Potent Anticancer Agent

Bhanja, P., Mishra, S., Manna, K., Mallick, A., Saha, K. D., & Bhaumik, A. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b07343 · Cited by 104

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Bao, L., Dou, G., Tian, R., Lv, Y., Ding, F., Liu, S., Zhao, R., Zhao, L., Zhou, J., Weng, L., et al. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.08.008 · Cited by 105

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Albright, J. M., Dunn, R. C., Shults, J. A., Boe, D. M., Afshar, M., & Kovacs, E. J. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6691 · Cited by 107

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Ley, K. F., Pramod, A. B., Croft, M., Ravichandran, K. S., & Ting, J. P. ‐. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00204 · Cited by 101

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Jondle, C. N., Gupta, K., Mishra, B. B., & Sharma, J. (2018) · PLoS Pathogens · doi:10.1371/journal.ppat.1007338 · Cited by 102

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Saddam, M., Paul, S. K., Habib, M. A., Fahim, M. A., Mimi, A. A., Islam, S., Paul, B., & Helal, M. M. U. (2024) · Egyptian Journal of Medical Human Genetics · doi:10.1186/s43042-024-00485-7 · Cited by 110

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Chauhan, D., Bartok, E., Gaidt, M. M., Bock, F. J., Herrmann, J. E., Seeger, J. M., Brož, P., Beckmann, R., Kashkar, H., Tait, S. W. G., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.10.087 · Cited by 103

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Belizário, J. E., Cordeiro, L., & Enns, S. C. (2015) · Mediators of Inflammation · doi:10.1155/2015/128076 · Cited by 106

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Bagalkot, V., Badgeley, M. A., Kampfrath, T., Deiuliis, J. A., Rajagopalan, S., & Maiseyeu, A. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.09.027 · Cited by 99

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Winkler, J. W., Orr, S. K., Dalli, J., Cheng, C.-Y. C., Sanger, J. M., Chiang, N., Petasis, N. A., & Serhan, C. N. (2016) · Scientific Reports · doi:10.1038/srep18972 · Cited by 100

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Preta, G. (2014) · International Journal of Cancer Studies & Research · doi:10.19070/2167-9118-140005e

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Yoon, K. W. (2017) · TANG [HUMANITAS MEDICINE] · doi:10.5667/tang.2016.0028

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Marek, C. J., & Erwig, L. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-381-7_11 · Cited by 1

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Michlewska, S., McColl, A., Rossi, A. G., Megson, I. L., & Dransfield, I. (2007) · Autoimmunity · doi:10.1080/08916930701357208 · Cited by 42