Monocytes and macrophages: developmental pathways and tissue homeostasis

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science · doi:10.1126/science.1194637 · Cited by 5,175

Macrophage biology in development, homeostasis and disease

Wynn, T. A., Chawla, A., & Pollard, J. W. (2013) · Nature · doi:10.1038/nature12034 · Cited by 4,684

Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties

Geissmann, F., Jung, S., & Littman, D. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00174-2 · Cited by 3,504

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

Yona, S., Kim, K.-W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., et al. (2013) · Immunity · doi:10.1016/j.immuni.2012.12.001 · Cited by 3,245

Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.4106-4114.2000 · Cited by 2,632

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

Schulz, C., Perdiguero, E. G., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., et al. (2012) · Science · doi:10.1126/science.1219179 · Cited by 2,578

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

Orkin, S. H., & Zon, L. I. (2008) · Cell · doi:10.1016/j.cell.2008.01.025 · Cited by 2,570

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

Hashimoto, D., Chow, A., Noizat, C., Teo, P., Beasley, M. B., Leboeuf, M., Becker, C. D., See, P., Price, J., Lucas, D., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.04.004 · Cited by 2,311

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

Swirski, F. K., Nahrendorf, M., Etzrodt, M., Wildgruber, M., Cortez-Retamozo, V., Panizzi, P., Figueiredo, J.-L., Kohler, R. H., Chudnovskiy, A., Waterman, P., et al. (2009) · Science · doi:10.1126/science.1175202 · Cited by 2,221

Pericytes are required for blood–brain barrier integrity during embryogenesis

Daneman, R., Zhou, L., Kebede, A. A., & Barres, B. A. (2010) · Nature · doi:10.1038/nature09513 · Cited by 2,128

Regulation of Monocyte Adhesion and Type I Interferon Signaling by CD52 in Patients With Systemic Sclerosis

Rudnik, M., Rolski, F., Jordan, S., Mertelj, T., Stellato, M., Distler, O., Błyszczuk, P., & Kania, G. (2021) · Arthritis & Rheumatology · doi:10.1002/art.41737 · Cited by 26

Effect of Multi-Strain Probiotic Supplementation on URTI Symptoms and Cytokine Production by Monocytes after a Marathon Race: A Randomized, Double-Blind, Placebo Study

Tavares-Silva, E., Caris, A. V., dos Santos, S. A., Ravacci, G. R., & dos Santos, R. V. T. (2021) · Nutrients · doi:10.3390/nu13051478 · Cited by 30

Macrophage membrane biomimetic drug delivery system: for inflammation targeted therapy

Zhang, Y., Long, Y., Wan, J., Liu, S., Shi, A., Li, D., Yu, S., Li, X., Wen, J., Deng, J., et al. (2022) · Journal of drug targeting · doi:10.1080/1061186x.2022.2071426 · Cited by 27

Quantitative whole-cell MALDI-TOF MS fingerprints distinguishes human monocyte sub-populations activated by distinct microbial ligands

Portevin, D., Pflüger, V., Otieno, P., Brunisholz, R., Vogel, G., & Daubenberger, C. (2015) · BMC Biotechnology · doi:10.1186/s12896-015-0140-1 · Cited by 26

IL-23 prevents IL-13-dependent tissue repair associated with Ly6C lo monocytes in Entamoeba histolytica -induced liver damage

Noll, J., Helk, E., Fehling, H., Bernin, H., Marggraff, C., Jacobs, T., Huber, S., Pelczar, P., Ernst, T., Ittrich, H., et al. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2016.01.013 · Cited by 27

Dual transcriptome sequencing reveals resistance of TLR4 ligand-activated bone marrow-derived macrophages to inflammation mediated by the BET inhibitor JQ1

Das, A., Chai, J. C., Yang, C., Lee, Y. S., Das, N. D., Jung, K. H., & Chai, Y. G. (2015) · Scientific Reports · doi:10.1038/srep16932 · Cited by 28

Macrophage Regulation during Vascular Remodeling: Implications for Pulmonary Hypertension Therapy

Pullamsetti, S. S., & Savai, R. (2017) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2017-0033ed · Cited by 26

Phenotypic and functional heterogeneity of human intermediate monocytes based on HLA ‐ DR expression

Connaughton, E. P., Naicker, S. D., Hanley, S. A., Slevin, S. M., Eykelenboom, J. K., Lowndes, N. F., O’Brien, T., Ceredig, R. H., Griffin, M. D., & Dennedy, M. C. (2018) · Immunology and Cell Biology · doi:10.1111/imcb.12032 · Cited by 26

Inhibition of SOX9 Promotes Inflammatory and Immune Responses of Dental Pulp

Luo, H., Wang, C., Liu, M., Yin, B., Peng, A., Huang, D., & Ye, L. (2018) · Journal of Endodontics · doi:10.1016/j.joen.2018.02.004 · Cited by 26

Differentiated macrophages acquire a pro-inflammatory and cell death–resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1

Rijal, D., Ariana, A., Wight, A. E., Kim, K., Alturki, N. A., Aamir, Z., Ametepe, E. S., Korneluk, R. G., Tiedje, C., Menon, M. B., et al. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.003614 · Cited by 26

Tissues: the unexplored frontier of antibody mediated immunity

Webb, N. E., Bernshtein, B., & Alter, G. (2021) · Current Opinion in Virology · doi:10.1016/j.coviro.2021.01.001 · Cited by 24

Immunomodulatory Effects of Gold Nanoparticles: Impacts on Immune Cells and Mechanisms of Action

Koushki, K., Biswal, P., Vijay, G. V., Sadeghi, M., Dehnavi, S., Tra, N. T., Samala, S. K., Taba, M. Y., Vasan, A. B., Han, E., et al. (2025) · Nanomaterials · doi:10.3390/nano15151201 · Cited by 28

Identification of Caspase-6 as a New Regulator of Alternatively Activated Macrophages

Yao, Y., Shi, Q., Chen, B., Wang, Q., Li, X., Li, L., Huang, Y., Ji, J., & Shen, P. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.717868 · Cited by 25

The CD300e molecule in mice is an immune-activating receptor

Isobe, M., Izawa, K., Sugiuchi, M., Sakanishi, T., Kaitani, A., Takamori, A., Maehara, A., Matsukawa, T., Takahashi, M., Yamanishi, Y., et al. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra117.000696 · Cited by 25

Astragaloside IV Attenuated 3,4-Benzopyrene-Induced Abdominal Aortic Aneurysm by Ameliorating Macrophage-Mediated Inflammation

Wang, J., Zhou, Y., Wu, S., Huang, K., Thapa, S., Tao, L., Wang, J., Shen, Y., Wang, J., Xue, Y., et al. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00496 · Cited by 25

Cytomegalovirus host entry and spread

Farrell, H. E., & Stevenson, P. G. (2019) · Journal of General Virology · doi:10.1099/jgv.0.001230 · Cited by 25

Immunoproteasome Inhibition Selectively Kills Human CD14+ Monocytes and as a Result Dampens IL-23 Secretion

Basler, M., Claus, M., Klawitter, M., Goebel, H., & Groettrup, M. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1900182 · Cited by 25

Expression of CD300lf by microglia contributes to resistance to cerebral malaria by impeding the neuroinflammation

Keswani, T., Roland, J., Herbert, F., Delcroix-Genête, D., Roy, H. B., Gaayeb, L., Cazenave, P., & Pied, S. (2019) · Genes and Immunity · doi:10.1038/s41435-019-0085-9 · Cited by 25

Altered Monocyte and Langerhans Cell Innate Immunity in Patients With Recurrent Respiratory Papillomatosis (RRP)

Israr, M., DeVoti, J. A., Lam, F., Abramson, A. L., Steinberg, B. M., & Bonagura, V. R. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00336 · Cited by 25

Targeting inflammatory monocytes by immune-modifying nanoparticles prevents acute kidney allograft rejection

Lai, C., Chadban, S. J., Loh, Y. W., Kwan, T., Wang, C., Singer, J., Niewold, P., Ling, Z. L., Spiteri, A. G., Getts, D. R., et al. (2022) · Kidney International · doi:10.1016/j.kint.2022.06.024 · Cited by 26

Targeting Ligand Independent Tropism of siRNA‐LNP by Small Molecules for Directed Therapy of Liver or Myeloid Immune Cells

Lin, C., Jans, A., Wolters, J. C., Mohamed, M. R., van der Vorst, E. P. C., Trautwein, C., & Bartneck, M. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202202670 · Cited by 25

scTenifoldXct: A semi-supervised method for predicting cell-cell interactions and mapping cellular communication graphs

Yang, Y., Li, G., Zhong, Y., Xu, Q., Lin, Y.-T., Roman-Vicharra, C., Chapkin, R. S., & Cai, J. J. (2023) · Cell Systems · doi:10.1016/j.cels.2023.01.004 · Cited by 26

PM 2.5 Increases Systemic Inflammatory Cells and Associated Disease Risks by Inducing NRF2-Dependent Myeloid-Biased Hematopoiesis in Adult Male Mice

Wang, Y., Jin, X., Li, M., Gao, J., Zhao, X., Ma, J., Shi, C., He, B., Hu, L., Shi, J., et al. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.2c09024 · Cited by 25

Differential MicroRNA Expression Levels in Cutaneous Acute Graft-Versus-Host Disease

Atarod, S., Norden, J., Bibby, L. A., Janin, A., Ratajczak, P., Lendrem, C., Pearce, K. F., Wang, X.-N., O’Reilly, S., van Laar, J. M., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01485 · Cited by 25

Trichuris suis induces human non-classical patrolling monocytes via the mannose receptor and PKC: implications for multiple sclerosis

Kooij, G., Braster, R., Koning, J. J., Laan, L. C., van Vliet, S. J., Los, T., Eveleens, A. M., van der Pol, S. M. A., Förster‐Waldl, E., Boztuǧ, K., et al. (2015) · Acta Neuropathologica Communications · doi:10.1186/s40478-015-0223-1 · Cited by 25

Atorvastatin alleviates renal ischemia-reperfusion injury in rats by promoting M1-M2 transition

Wang, Q., Su, Y., Li, Y., Zhang, Y., Yang, S., Wang, J., & Li, H. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.6074 · Cited by 25

Reverse transendothelial cell migration in inflammation: to help or to hinder?

Burn, T. N., & Alvarez, J. I. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2444-2 · Cited by 28

TIPE2 governs macrophage polarization via negative regulation of mTORC1

Jiang, Y., Li, Q., Zhang, Y., Gao, Y., Jiang, L., & Chen, Z. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.7991 · Cited by 25

Absence of the Non-Signalling Chemerin Receptor CCRL2 Exacerbates Acute Inflammatory Responses In Vivo

Regan-Komito, D., Valaris, S., Kapellos, T. S., Recio, C., Taylor, L., Greaves, D. R., & Iqbal, A. J. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01621 · Cited by 23

Physiology of cardiac development: from genetics to signaling to therapeutic strategies

Sun, C., & Kontaridis, M. I. (2017) · Current Opinion in Physiology · doi:10.1016/j.cophys.2017.09.002 · Cited by 28

IRF5 Is a Key Regulator of Macrophage Response to Lipopolysaccharide in Newborns

Schneider, A., Weier, M., Herderschee, J., Perreau, M., Calandra, T., Roger, T., & Giannoni, É. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01597 · Cited by 27

Comparing the Metabolic Capabilities of Bacteria in the Mycobacterium tuberculosis Complex

Fieweger, R. A., Wilburn, K. M., & VanderVen, B. C. (2019) · Microorganisms · doi:10.3390/microorganisms7060177 · Cited by 28

Mechanisms Underlying the Selection and Function of Macrophage-Specific EnhancersPreprint

Link, V. M., Gosselin, D., & Glass, C. K. (2015) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2015.80.027367 · Cited by 25

RARα supports the development of Langerhans cells and langerin-expressing conventional dendritic cells

Hashimoto-Hill, S., Friesen, L., Park, S., Im, S., Kaplan, M. H., & Kim, C. H. (2018) · Nature Communications · doi:10.1038/s41467-018-06341-8 · Cited by 24

Biomimetic Systems Involving Macrophages and Their Potential for Targeted Drug Delivery

Savchenko, I. V., Zlotnikov, I. D., & Kudryashova, E. V. (2023) · Biomimetics · doi:10.3390/biomimetics8070543 · Cited by 25

The contribution of the monocyte-macrophage lineage to immunotherapy outcomes

Adams, R. C., MacDonald, K. P. A., & Hill, G. R. (2024) · Blood · doi:10.1182/blood.2024025680 · Cited by 26

IFN-γ in tissue-immune homeostasis and antitumor immunity

Kwon, B. (2017) · Cellular and Molecular Immunology · doi:10.1038/cmi.2017.95 · Cited by 24

Methods to Study Monocyte and Macrophage Trafficking in Atherosclerosis Progression and Resolution

Weinstock, A., & Fisher, E. A. A. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9130-3_12 · Cited by 24

Macrophages in Atheromatous Plaque Developmental Stages

von Ehr, A., Bode, C., & Hilgendorf, I. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.865367 · Cited by 24

THP-1 cell line model for tuberculosis: A platform for in vitro macrophage manipulation

Shah, P. T., Tufail, M., Wu, C., & Xing, L. (2022) · Tuberculosis · doi:10.1016/j.tube.2022.102243 · Cited by 24

A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling

Zhu, L., Tang, Y., Li, X., Kerk, S. A., Lyssiotis, C. A., Feng, W., Sun, X., Hespe, G. E., Wang, Z., Stemmler, M. P., et al. (2023) · The EMBO Journal · doi:10.15252/embj.2022111148 · Cited by 25

Indigenous microbiota and Leishmaniasis

Lopes, M. E., Carneiro, M. B. H., dos Santos, L. M., & Vieira, L. Q. (2015) · Parasite Immunology · doi:10.1111/pim.12279 · Cited by 26

S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1βor Lipocalin-2

Syed, S. N., Jung, M., Weigert, A., & Brüne, B. (2017) · Mediators of Inflammation · doi:10.1155/2017/7510496 · Cited by 24

Role of the immune response in initiating central nervous system regeneration in vertebrates: learning from the fish

Bosak, V., Murata, K., Bludau, O., & Brand, M. (2018) · The International Journal of Developmental Biology · doi:10.1387/ijdb.180033vb · Cited by 24

MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages

An, J., Naruse, T. K., Hinohara, K., Soejima, Y., Sawabe, M., Nakagawa, Y., Kuwahara, K., & Kimura, A. (2019) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2019.05.015 · Cited by 23

Mutual epithelium‐macrophage dependency in liver carcinogenesis mediated by ST18

Ravà, M., D’Andrea, A., Doni, M., Kress, T. R., Ostuni, R., Bianchi, V., Morelli, M. J., Collino, A., Ghisletti, S., Nicoli, P., et al. (2016) · Hepatology · doi:10.1002/hep.28942 · Cited by 24

Do Vascular Smooth Muscle Cells Differentiate to Macrophages in Atherosclerotic Lesions?

Świrski, F. K., & Nahrendorf, M. (2014) · Circulation Research · doi:10.1161/circresaha.114.304925 · Cited by 26

Disparate macrophage responses are linked to infection outcome of Hantan virus in humans or rodents

Ma, H., Yang, Y., Nie, T., Yan, R., Si, Y., Wei, J., Li, M., Liu, H., Ye, W., Zhang, H., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-44687-4 · Cited by 22

Spatiotemporal Analysis of Mesenchymal Stem Cells Fate Determination by Inflammatory Niche Following Soft Tissue Injury at a Single‐Cell Level

Chen, K., Tan, Z., Wang, H., Wang, W., Yang, J., Zhang, Y., Lu, X., Cheng, Q., Chai, L., Peng, C., et al. (2024) · Advanced Science · doi:10.1002/advs.202310282 · Cited by 26

Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson’s disease model mice

Song, W., Zhou, Z.-M., Zhang, L., Shu, H.-F., Xia, J.-R., Qin, X., Hua, R., & Zhang, Y. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07333-5 · Cited by 25

Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation

Jhunjhunwala, S., Álvarez, D., Aresta-Dasilva, S., Tang, K., Tang, B. C., Greiner, D. L., Newburger, P. E., von Andrian, U. H., Langer, R., & Anderson, D. G. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.1hi0615-248rr · Cited by 23

Upregulation of miR-196b-5p attenuates BCG uptake via targeting SOCS3 and activating STAT3 in macrophages from patients with long-term cigarette smoking-related active pulmonary tuberculosis

Yuan, Y., Lin, D., Feng, L., Huang, M., Yan, H., Li, Y., Chen, Y., Lin, B., Ma, Y., Ye, Z., et al. (2018) · Journal of Translational Medicine · doi:10.1186/s12967-018-1654-9 · Cited by 23

Pro-inflammatory agents released by pathogens, dying host cells, and neutrophils act synergistically to destroy host tissues: a working hypothesis

Ginsburg, I., Korem, M., Koren, E., & Varani, J. (2019) · Journal of Inflammation Research · doi:10.2147/jir.s190007 · Cited by 24

Macrophage Targeting pH Responsive Polymersomes for Glucocorticoid Therapy

Gouveia, V. M., Rizzello, L., Nunes, C., Poma, A., Ruiz‐Pérez, L., Oliveira, A., Reis, S., & Battaglia, G. (2019) · Pharmaceutics · doi:10.3390/pharmaceutics11110614 · Cited by 23

Classic and new mediators for in vitro modelling of human macrophages

Luque-Martin, R., Mander, P. K., Leenen, P. J. M., & de Winther, M. P. J. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.1ru0620-018r · Cited by 24

Signal Pathways Involved in the Interaction Between Tumor-Associated Macrophages/TAMs and Glioblastoma Cells

Liu, X., Liu, Y., Qi, Y., Huang, Y., Hu, F., Dong, F., Shu, K., & Lei, T. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.822085 · Cited by 27

Dynamic immune recovery process after liver transplantation revealed by single-cell multi-omics analysis

Wang, R., Peng, X., Yuan, Y., Shi, B., Liu, Y., Ni, H., Guo, W., Yang, Q., Liu, P., Wang, J., et al. (2024) · The Innovation · doi:10.1016/j.xinn.2024.100599 · Cited by 23

Fate PPAR-titioning: PPAR-γ 'instructs' alveolar macrophage development

Ginhoux, F. (2014) · Nature Immunology · doi:10.1038/ni.3011 · Cited by 23

Regulation of monocyte induced cell migration by the RNA binding protein, FXR1

Tonquèze, O. L., Kollu, S., Lee, S., Al-Salah, M., Truesdell, S. S., & Vasudevan, S. (2016) · Cell Cycle · doi:10.1080/15384101.2016.1189040 · Cited by 21

Role of monocytes and endothelial cells in heparin-induced thrombocytopenia

Madeeva, D. V., Cines, D. B., Poncz, M., & Rauova, L. (2016) · Thrombosis and Haemostasis · doi:10.1160/th16-02-0162 · Cited by 23

Dendritic cell analysis in primary immunodeficiency

Bigley, V., Barge, D., & Collin, M. (2016) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0000000000000322 · Cited by 23

Phenotype and Tissue Residency of Lymphocytes in the Murine Oral Mucosa

Park, J., Chung, H., Choi, Y., & Park, J.-H. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00250 · Cited by 23

The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis

Pei, X., Zheng, D., She, S., Ma, J., Guo, C., Mo, X., Zhang, Y., Song, Q., Zhang, Y., Ma, D., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-05255-7 · Cited by 22

Modulation of innate and adaptive immune responses by arabinoxylans

Fadel, A., Plunkett, A., Li, W., Gyamfi, V. E. T., Nyaranga, R. R., Fadel, F., Dakak, S., Ranneh, Y., Salmon, Y., & Ashworth, J. (2017) · Journal of Food Biochemistry · doi:10.1111/jfbc.12473 · Cited by 23

Monocyte NOTCH2 expression predicts IFN-β immunogenicity in multiple sclerosis patients

Adriani, M., Nytrová, P., Mbogning, C., Hässler, S., Medek, K., Jensen, P. E., Creeke, P. I., Warnke, C., Ingenhoven, K., Hemmer, B., et al. (2018) · JCI Insight · doi:10.1172/jci.insight.99274 · Cited by 23

Multivalent nanosystems: targeting monocytes/macrophages

Poupot, R., Goursat, C., & Fruchon, S. (2018) · International Journal of Nanomedicine · doi:10.2147/ijn.s146192 · Cited by 23

Sleep enhances numbers and function of monocytes and improves bacterial infection outcome in mice

Hahn, J. K., Günter, M., Schuhmacher, J., Bieber, K., Pöschel, S., Schütz, M., Engelhardt, B., Oster, H., Sina, C., Lange, T., et al. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2020.01.001 · Cited by 23

p110δ PI3K as a therapeutic target of solid tumours

Xenou, L., & Papakonstanti, E. A. (2020) · Clinical Science · doi:10.1042/cs20190772 · Cited by 23

Apoptosis of hematopoietic progenitor-derived adipose tissue–resident macrophages contributes to insulin resistance after myocardial infarction

Vasamsetti, S. B., Coppin, E., Zhang, X., Florentin, J., Koul, S. M., Götberg, M., Clugston, A. S., Thoma, F. W., Sembrat, J., Bullock, G. C., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aaw0638 · Cited by 23

The Assembly of EDC4 and Dcp1a into Processing Bodies Is Critical for the Translational Regulation of IL-6

Seto, E., Yoshida-Sugitani, R., Kobayashi, T., & Toyama‐Sorimachi, N. (2015) · PLoS ONE · doi:10.1371/journal.pone.0123223 · Cited by 23

Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis

Alturki, N. A., McComb, S., Ariana, A., Rijal, D., Korneluk, R. G., Sun, S., Alnemri, E. S., & Sad, S. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0672-0 · Cited by 25

Characteristics of activation of monocyte-derived macrophages versus microglia after mouse experimental intracerebral hemorrhage

Ye, F., Yang, J., Holste, K. G., Koduri, S., Hua, Y., Keep, R. F., Garton, H. J. L., & Xi, G. (2023) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x231173187 · Cited by 23

Elevated glycolytic metabolism of monocytes limits the generation of HIF1A-driven migratory dendritic cells in tuberculosis

Maio, M., Barros, J., Joly, M., Vahlas, Z., Franco, J. L. M., Genoula, M., Monard, S., Vecchione, M. B., Fuentes, F., Polo, V. G., et al. (2023) · eLife · doi:10.7554/elife.89319 · Cited by 27

Intersection of Immunology and Metabolism in Myocardial Disease

Thorp, E. B., & Karlstaedt, A. (2024) · Circulation Research · doi:10.1161/circresaha.124.323660 · Cited by 27

Classical monocyte ontogeny dictates their functions and fates as tissue macrophages

Trzebanski, S., Kim, J.-S., Larossi, N., Raanan, A., Kancheva, D., Bastos, J., Haddad, M., Solomon, A., Sivan, E., Aizik, D., et al. (2024) · Immunity · doi:10.1016/j.immuni.2024.06.011 · Cited by 23

Dendritic Cells: Origin, Classification, Development, Biological Functions, and Therapeutic Potential

Jin, F., Xie, L., Zhang, H., Fan, X., Tian, J., Liu, W., Xiao, Y., & Fan, X. (2025) · MedComm · doi:10.1002/mco2.70455 · Cited by 29

An Aeromonas variant that produces aerolysin promotes susceptibility to ulcerative colitis

Jiang, Z., Wang, Y., Gong, J., Chen, X., Hang, D., Chen, C., Hong, X., Zhang, J., Qiu, K., Liao, Y., et al. (2025) · Science · doi:10.1126/science.adz4712 · Cited by 22

Microglia across evolution: from conserved origins to functional divergence

Shimizu, T., & Prinz, M. (2025) · Cellular and Molecular Immunology · doi:10.1038/s41423-025-01368-6 · Cited by 28

2015 Russell Ross Memorial Lecture in Vascular Biology

Ley, K. F. (2016) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.115.306009 · Cited by 22

Antiinflammatory Activity of a Novel Folic Acid Targeted Conjugate of the mTOR Inhibitor Everolimus

Lu, Y. J., Parker, N. L., Kleindl, P. J., Cross, V. A., Wollak, K. N., Westrick, E. M., Stinnette, T. W., Gehrke, M. A., Wang, K., Santhapuram, H. K. R., et al. (2015) · Molecular Medicine · doi:10.2119/molmed.2015.00040 · Cited by 22

Self-Renewal of Macrophages: Tumor-Released Factors and Signaling Pathways

Filiberti, S., Russo, M., Lonardi, S., Bugatti, M., Vermi, W., Tournier, C., & Giurisato, E. (2022) · Biomedicines · doi:10.3390/biomedicines10112709 · Cited by 25

Potential therapeutic targets of macrophages in inhibiting immune damage and fibrotic processes in musculoskeletal diseases

Zhu, J., Fan, J., Xia, Y., Wang, H., Li, Y., Feng, Z., & Fu, C. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1219487 · Cited by 26

The Role and Therapeutic Implications of Inflammation in the Pathogenesis of Brain Arteriovenous Malformations

Ricciardelli, A., Robledo, A., Fish, J. E., Kan, P. T. M., Harris, T. H., & Wythe, J. D. (2023) · Biomedicines · doi:10.3390/biomedicines11112876 · Cited by 24

Single-cell transcriptomics of bronchoalveolar lavage during PRRSV infection with different virulence

Lim, B., Kim, S.-C., Kim, H.-J., Kim, J.-H., Seo, Y.-J., Lim, C., Park, Y., Sheet, S., Kim, D., Lim, D.-H., et al. (2025) · Nature Communications · doi:10.1038/s41467-024-54676-2 · Cited by 23

Immune Suppression by Myeloid Cells in HIV Infection: New Targets for Immunotherapy

Mehraj, V., Jenabian, M.-A., Vyboh, K., & Routy, J. (2014) · The Open AIDS Journal · doi:10.2174/1874613601408010066 · Cited by 22

On the Functional Overlap between Complement and Anti-Microbial Peptides

Zimmer, J., Hobkirk, J., Mohamed, F., Browning, M. J., & Stover, C. M. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00689 · Cited by 22

CD11chi Dendritic Cells Regulate Ly-6Chi Monocyte Differentiation to Preserve Immune-privileged CNS in Lethal Neuroinflammation

Kim, J. H., Choi, J., Kim, S. B., Uyangaa, E., Patil, A. M., Han, Y. W., Park, S., Lee, J. H., Kim, K., & Eo, S. K. (2015) · Scientific Reports · doi:10.1038/srep17548 · Cited by 22

Inflammation et régénération musculaire

Dufresne, S. S., Frenette, J., & Dumont, N. A. (2016) · médecine/sciences · doi:10.1051/medsci/20163206022 · Cited by 25

Host Response to Implanted Materials and Devices: An Overview

Scarritt, M. E., Londoño, R., & Badylak, S. F. (2016) · Springer eBooks · doi:10.1007/978-3-319-45433-7_1 · Cited by 21

Morphology, Aggregation Properties, Cytocompatibility, and Anti-Inflammatory Potential of Citrate-Stabilized AuNPs Prepared by Modular Ultrasonic Spray Pyrolysis

Rudolf, R., Majerič, P., Tomić, S., Shariq, M., Ferčec, U., Budič, B., Friedrich, B. G., Vučević, D., & Čolić, M. J. (2017) · Journal of Nanomaterials · doi:10.1155/2017/9365012 · Cited by 22

The Role of (Modified) Lipoproteins in Vascular Function: A Duet Between Monocytes and the Endothelium

Schnitzler, J. G., Dallinga‐Thie, G. M., & Kroon, J. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867325666180316121015 · Cited by 23

Effect of Orally Administered Atractylodes macrocephala Koidz Water Extract on Macrophage and T Cell Inflammatory Response in Mice

Kwak, T.-K., Jang, H.-S., Lee, M., Jung, Y. S., Kim, D., Kim, Y., Kim, J., & Kang, H. G. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/4041873 · Cited by 22

Influence of Immunological Maturity on Respiratory Syncytial Virus-Induced Morbidity in Young Children

Verhoeven, D. E. (2018) · Viral Immunology · doi:10.1089/vim.2018.0121 · Cited by 23

Regulation of Monocyte-Macrophage Responses in Cirrhosis—Role of Innate Immune Programming and Checkpoint Receptors

Riva, A., & Mehta, G. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00167 · Cited by 23

Changes in the Molecular and Functional Phenotype of Bovine Monocytes during Theileria parva Infection

Bastos, R. G., Sears, K. P., Dinkel, K. D., Knowles, D. P., & Fry, L. M. (2019) · Infection and Immunity · doi:10.1128/iai.00703-19 · Cited by 22

Immunomodulation for maxillofacial reconstructive surgery

Kim, S. (2020) · Maxillofacial Plastic and Reconstructive Surgery · doi:10.1186/s40902-020-00249-4 · Cited by 22

B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity

McKee, S. J., Tuong, Z. K., Kobayashi, T., Doff, B. L., Soon, M. S. F., Nissen, M. D., Lam, P. Y., Keane, C., Vari, F., Moi, D., et al. (2017) · OncoImmunology · doi:10.1080/2162402x.2017.1393599 · Cited by 22

Systems immunology allows a new view on human dendritic cells

Schultze, J. L., & Aschenbrenner, A. C. (2018) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2018.02.017 · Cited by 25

Understanding the Cellular Origin of the Mononuclear Phagocyte System Sheds Light on the Myeloid Postulate of Immune Paralysis in Sepsis

Poulin, L. F., Lasseaux, C., & Chamaillard, M. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00823 · Cited by 23

SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2Preprint

Chen, S., Yang, L., Nilsson-Payant, B. E., Han, Y., Jaffré, F., Zhu, J., Wang, P., Zhang, T., Redmond, D., Houghton, S., et al. (2020) · doi:10.21203/rs.3.rs-94634/v1 · Cited by 22

The origins and homeostasis of monocytes and tissue‐resident macrophages in physiological situation

Zhao, Y., Zou, W., Du, J., & Zhao, Y. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26461 · Cited by 190

Tissue-Resident Macrophage Ontogeny and Homeostasis

Ginhoux, F., & Guilliams, M. (2016) · Immunity · doi:10.1016/j.immuni.2016.02.024 · Cited by 1,884

The Mononuclear Phagocyte System: The Relationship between Monocytes and Macrophages

Hume, D. A., Irvine, K. M., & Pridans, C. (2018) · Trends in Immunology · doi:10.1016/j.it.2018.11.007 · Cited by 270

Physiological roles of macrophages

Gordon, S., & Martínez‐Pomares, L. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1945-7 · Cited by 242

Origin, development, and homeostasis of tissue‐resident macrophages

Haldar, M., & MURPHY, K. M. M. (2014) · Immunological Reviews · doi:10.1111/imr.12215 · Cited by 125