Monocytes and macrophages: developmental pathways and tissue homeostasis

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science · doi:10.1126/science.1194637 · Cited by 5,175

Macrophage biology in development, homeostasis and disease

Wynn, T. A., Chawla, A., & Pollard, J. W. (2013) · Nature · doi:10.1038/nature12034 · Cited by 4,684

Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties

Geissmann, F., Jung, S., & Littman, D. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00174-2 · Cited by 3,504

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

Yona, S., Kim, K.-W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., et al. (2013) · Immunity · doi:10.1016/j.immuni.2012.12.001 · Cited by 3,245

Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.4106-4114.2000 · Cited by 2,632

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

Schulz, C., Perdiguero, E. G., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., et al. (2012) · Science · doi:10.1126/science.1219179 · Cited by 2,578

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

Orkin, S. H., & Zon, L. I. (2008) · Cell · doi:10.1016/j.cell.2008.01.025 · Cited by 2,570

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

Hashimoto, D., Chow, A., Noizat, C., Teo, P., Beasley, M. B., Leboeuf, M., Becker, C. D., See, P., Price, J., Lucas, D., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.04.004 · Cited by 2,311

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

Swirski, F. K., Nahrendorf, M., Etzrodt, M., Wildgruber, M., Cortez-Retamozo, V., Panizzi, P., Figueiredo, J.-L., Kohler, R. H., Chudnovskiy, A., Waterman, P., et al. (2009) · Science · doi:10.1126/science.1175202 · Cited by 2,221

Pericytes are required for blood–brain barrier integrity during embryogenesis

Daneman, R., Zhou, L., Kebede, A. A., & Barres, B. A. (2010) · Nature · doi:10.1038/nature09513 · Cited by 2,128

Dual COX-2/TNF-α Inhibitors as Promising Anti-inflammatory and Cancer Chemopreventive Agents: A Review

Tajdari, M., Peyrovinasab, A., Bayanati, M., Rabbani, M. I. M., Abdolghaffari, A. H., & Zarghi, A. (2024) · Iranian journal of pharmaceutical research · doi:10.5812/ijpr-151312 · Cited by 29

Foamy macrophages in atherosclerosis: unraveling the balance between pro- and anti-inflammatory roles in disease progression

Ijaz, A., Yarlagadda, B. R. G., & Orecchioni, M. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1589629 · Cited by 26

Thromboinflammation vs. immunothrombosis: strategies for overcoming anticoagulant resistance in COVID-19 and other hyperinflammatory diseases. Is ROTEM helpful or not?

Almskog, L. M., & Ågren, A. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1599639 · Cited by 24

Norepinephrine promotes triglyceride storage in macrophages via beta2‐adrenergic receptor activation

Petkevicius, K., Bidault, G., Virtue, S., Jenkins, B., van Dierendonck, X. A. M. H., Dugourd, A. J. F., Sáez-Rodríguez, J., Stienstra, R., Koulman, A., & Vidal‐Puig, A. (2021) · The FASEB Journal · doi:10.1096/fj.202001101r · Cited by 21

Histiocytic and Dendritic Cell Neoplasms

Pan, Z., & Xu, M. L. (2019) · Surgical pathology clinics · doi:10.1016/j.path.2019.03.013 · Cited by 21

The Effects of Macrophage Phenotype on Osteogenic Differentiation of MSCs in the Presence of Polyethylene Particles

Gao, Q., Rhee, C., Maruyama, M., Li, Z. A., Shen, H., Zhang, N., Utsunomiya, T., Huang, E. E., Yao, Z., Bunnell, B. A., et al. (2021) · Biomedicines · doi:10.3390/biomedicines9050499 · Cited by 21

Stimulation of Innate and Adaptive Immune Cells with Graphene Oxide and Reduced Graphene Oxide Affect Cancer Progression

Yunus, M. A., Ramli, M. M., Osman, N. H., & Mohamed, R. (2021) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-021-00625-6 · Cited by 21

Different Spatial and Temporal Roles of Monocytes and Monocyte-Derived Cells in the Pathogenesis of an Imiquimod Induced Lupus Model

Nomura, A., Mizuno, M., Noto, D., Aoyama, A., Kuga, T., Murayama, G., Chiba, A., & Miyake, S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.764557 · Cited by 21

Perspective Review of Myeloid Immune Cell Responses and Poststroke Immunosuppression

Xie, W., Simats, A., Guo, Y., Huang, T., Sun, X., Chen, W., Lin, Y., Wang, X., Lai, Z., Yu, W., et al. (2023) · Stroke · doi:10.1161/strokeaha.122.042075 · Cited by 21

Linking immune responses with fibrosis in allergic eye disease

Dale, S. B., & Saban, D. R. (2015) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0000000000000197 · Cited by 21

Master and commander: epigenetic regulation of macrophages

Netea, M. G., & Joosten, L. A. B. (2016) · Cell Research · doi:10.1038/cr.2016.5 · Cited by 21

Resident macrophages in the healthy and inflamed intestinal muscularis externa

Wehner, S., & Engel, D. R. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1948-4 · Cited by 22

New interplay between interstitial and alveolar macrophages explains pulmonary alveolar proteinosis (PAP) induced by indium tin oxide particles

Huaux, F., Gussem, V. D., Lebrun, A., Yakoub, Y., Palmai‐Pallag, M., Ibouraadaten, S., Uwambayinema, F., & Lison, D. (2018) · Archives of Toxicology · doi:10.1007/s00204-018-2168-1 · Cited by 21

The oligosaccharides 6’-sialyllactose, 2’-fucosyllactose or galactooligosaccharides do not directly modulate human dendritic cell differentiation or maturation

Perdijk, O., van Neerven, R. J. J., van den Brink, E., Savelkoul, H. F. J., & Brugman, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0200356 · Cited by 21

Weathering the Storm: Harnessing the Resolution of Inflammation to Limit COVID-19 Pathogenesis

Silberberg, E., Filep, J. G., & Ariel, A. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.863449 · Cited by 22

Gestational restricted- and over-feeding promote maternal and offspring inflammatory responses that are distinct and dependent on diet in sheep†

Jones, A. K., Hoffman, M. L., Pillai, S. M., McFadden, K. K., Govoni, K. E., Zinn, S. A., & Reed, S. A. (2017) · Biology of Reproduction · doi:10.1093/biolre/iox174 · Cited by 22

Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit

Kayyal, H., Cruciani, F., Chandran, S. K., Edry, E., Schif‐Zuck, S., Koren, T., Yiannakas, A., Rolls, A., Ariel, A., & Rosenblum, K. (2025) · Nature Neuroscience · doi:10.1038/s41593-024-01864-4 · Cited by 20

Neuroinflammation, Blood–Brain Barrier, and HIV Reservoirs in the CNS: An In-Depth Exploration of Latency Mechanisms and Emerging Therapeutic Strategies

Said, N., & Venketaraman, V. (2025) · Viruses · doi:10.3390/v17040572 · Cited by 26

A Csf1r-EGFP Transgene Provides a Novel Marker for Monocyte Subsets in Sheep

Pridans, C., Davis, G. M., Sauter, K. A. D., Lisowski, Z. M., Corripio‐Miyar, Y., Raper, A., Lefèvre, L., Young, R. A., McCulloch, M. E. B., Lillico, S. G., et al. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1502336 · Cited by 21

Neural architecture in lymphoid organs: Hard‐wired antigen presenting cells and neurite networks in antigen entrance areas

Wülfing, C., Schuran, F. A., Urban, J., Oehlmann, J., & Günther, H. S. (2018) · Immunity Inflammation and Disease · doi:10.1002/iid3.223 · Cited by 20

Investigation into the role of macrophages heterogeneity on solid tumour aggregations

Eftimie, R. (2020) · Mathematical Biosciences · doi:10.1016/j.mbs.2020.108325 · Cited by 20

Characterizing Chemotherapy-Induced Neutropenia and Monocytopenia Through Mathematical Modelling

Cassidy, T., Humphries, A. R., Craig, M., & Mackey, M. C. (2020) · Bulletin of Mathematical Biology · doi:10.1007/s11538-020-00777-0 · Cited by 21

Early monocyte modulation by the non-erythropoietic peptide ARA 290 decelerates AD-like pathology progression

Al‐Onaizi, M., Thériault, P., Lecordier, S., Préfontaine, P., Rivest, S., & ElAli, A. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.07.016 · Cited by 20

A Novel Regulatory Player in the Innate Immune System: Long Non-Coding RNAs

Xie, Y., & Wei, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179535 · Cited by 20

Novel population of human monocyte and osteoclast progenitors from pluripotent stem cells and peripheral blood

Root, S. H., & Aguila, H. L. (2021) · Blood Advances · doi:10.1182/bloodadvances.2021004552 · Cited by 19

Nonclassical Monocytes Are Prone to Migrate Into Tumor in Diffuse Large B-Cell Lymphoma

Gallou, S. L., Lhomme, F., Irish, J. M., Mingam, A., Pangault, C., Monvoisin, C., Ferrant, J., Azzaoui, I., Delphine Rossille, A., Bouabdallah, K. K., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.755623 · Cited by 19

Cutting Edge: Neutrophils License the Maturation of Monocytes into Effective Antifungal Effectors

Espinosa, V., Dutta, O., Heung, L. J., Wang, K., Chang, Y., Soteropoulos, P., Hohl, T. M., Siracusa, M. C., & Rivera, A. (2022) · The Journal of Immunology · doi:10.4049/jimmunol.2200430 · Cited by 22

Immune regulation based on sex differences in ischemic stroke pathology

Niu, P., Li, L., Zhang, Y., Su, Z., Wang, B., Liu, H., Zhang, S., Qiu, S., & Li, Y. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1087815 · Cited by 23

Leukocyte Adhesion Deficiency IV. Monocyte Integrin Activation Deficiency in Cystic Fibrosis

Fan, Z., & Ley, K. F. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201512-2454ed · Cited by 20

NLRP4 is an essential negative regulator of fructose-induced cardiac injury in vitro and in vivo

Lian, Y., Zhao, H., Wang, S.-J., Xu, Q.-L., & Xia, X.-J. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.04.120 · Cited by 20

Non-neoplastic histiocytic and dendritic cell disorders in lymph nodes

Egan, C., & Jaffe, E. S. (2017) · Seminars in Diagnostic Pathology · doi:10.1053/j.semdp.2017.11.002 · Cited by 20

Expression of tenascin C in cardiovascular lesions of Kawasaki disease

Yokouchi, Y., Oharaseki, T., Enomoto, Y., Sato, W., Imanaka‐Yoshida, K., & Takahashi, K. (2018) · Cardiovascular Pathology · doi:10.1016/j.carpath.2018.10.005 · Cited by 20

Proteomic analysis reveals a protective role of specific macrophage subsets in liver repair

Yang, W., Zhao, X., Tao, Y., Wu, Y. R., He, F., & Tang, L. (2019) · Scientific Reports · doi:10.1038/s41598-019-39007-6 · Cited by 21

Human macrophages and innate lymphoid cells: Tissue-resident innate immunity in humanized mice

Alisjahbana, A., Mohammad, I., Gao, Y., Evren, E., Ringqvist, E. E., & Willinger, T. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.113672 · Cited by 22

Distinct signals and immune cells drive liver pathology and glomerulonephritis in ABIN1[D485N] mice

Nanda, S. K., Petrova, T., Marchesi, F., Gierliński, M., Razsolkov, M., Lee, K. L., Wright, S. W., Rao, V. R., Cohen, P., & Arthur, J. S. C. (2019) · Life Science Alliance · doi:10.26508/lsa.201900533 · Cited by 20

Myeloid and Plasmacytoid Dendritic Cells and Cancer – New Insights

Gulubova, M. V., Ivanova, K. V., Hadzhi, M., Chonov, D., Ignatova, M. M., & Ananiev, J. (2019) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2019.735 · Cited by 20

EP3 signaling in dendritic cells promotes liver repair by inducing IL‐13‐mediated macrophage differentiation in mice

Nakamoto, S., Ito, Y., Nishizawa, N., Goto, T., Kojo, K., Kumamoto, Y., Watanabe, M., Narumiya, S., & Majima, M. (2020) · The FASEB Journal · doi:10.1096/fj.201901955r · Cited by 20

Monocyte Subsets With High Osteoclastogenic Potential and Their Epigenetic Regulation Orchestrated by IRF8

Das, A., Wang, X., Kang, J. M., Coulter, A. M., Shetty, A. C., Bachu, M., Brooks, S. R., Dell’Orso, S., Foster, B. L., Fan, X., et al. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4165 · Cited by 19

The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages

Sato, R., Reuter, T., Hiranuma, R., Shibata, T., Fukui, R., Motoi, Y., Murakami, Y., Tsukamoto, H., Yamazaki, S., Liu, K., et al. (2020) · International Immunology · doi:10.1093/intimm/dxaa055 · Cited by 22

Infiltration of the Hoffa's fat pad with stromal vascular fraction in patients with osteoarthritis of the knee -Results after one year of follow-up-

Labarre, K. W., & Zimmermann, G. (2022) · Bone Reports · doi:10.1016/j.bonr.2022.101168 · Cited by 20

HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice

Perdomo-Celis, F., Medina-Moreno, S., Davis, H., Bryant, J., & Zapata, J. C. (2019) · Pathogens · doi:10.3390/pathogens8010033 · Cited by 20

Deciphering m6A methylation in monocyte-mediated cardiac fibrosis and monocyte-hitchhiked erythrocyte microvesicle biohybrid therapy

Li, J., Li, W., Hu, K., He, Y., Gong, G., Liu, Q., Zhang, Y., Zhou, K., Guo, J., Hua, Y., et al. (2024) · Theranostics · doi:10.7150/thno.95664 · Cited by 19

Neuroprotective liver portal area macrophages attenuate hepatic inflammation

Xu, M., Liu, Z., Pan, Q., Cai, Z., Li, X., Huang, S., Wang, X., Xu, Y., Liu, J., Zhai, Y., et al. (2025) · Nature Immunology · doi:10.1038/s41590-025-02190-y · Cited by 23

Fcmr regulates mononuclear phagocyte control of anti-tumor immunity

Kubli, S. P., Vornholz, L., Duncan, G. S., Zhou, W., Ramachandran, P., Fortin, J., Cox, M. A., Han, S., Nechanitzky, R., Nechanitzky, D., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-10619-w · Cited by 20

A Low-Serum Culture System for Prolonged in Vitro Toxicology Experiments on a Macrophage System

Dalzon, B., Torres, A., Devcic, J., Fenel, D., Sergent, J., & Rabilloud, T. (2021) · Frontiers in Toxicology · doi:10.3389/ftox.2021.780778 · Cited by 20

New insights into macrophage subsets in atherosclerosis

Wang, Y., Wang, Q. A., & Xu, D. (2022) · Journal of Molecular Medicine · doi:10.1007/s00109-022-02224-0 · Cited by 19

Deciphering the Effects of 2D Black Phosphorus on Disrupted Hematopoiesis and Pulmonary Immune Homeostasis Using a Developed Flow Cytometry Method

Wang, Y., Li, M., Wang, S., Ma, J., Liu, Y., Guo, H., Gao, J., Yao, L., He, B., Hu, L., et al. (2022) · Environmental Science & Technology · doi:10.1021/acs.est.2c03675 · Cited by 19

The hypoxic tissue microenvironment as a driver of mucosal inflammatory resolution

Cartwright, I. M., & Colgan, S. P. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1124774 · Cited by 18

Mechanism of inflammatory response and therapeutic effects of stem cells in ischemic stroke: current evidence and future perspectives

Wang, Y., Yuan, T., Lyu, T., Zhang, L., Wang, M., He, Z., Wang, Y., & Li, Z. (2024) · Neural Regeneration Research · doi:10.4103/1673-5374.393104 · Cited by 20

Transcription Factor NRF2 in Shaping Myeloid Cell Differentiation and Function

Pfefferlé, M., & Vallelian, F. (2024) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-62731-6_8 · Cited by 18

Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis

Liu, X., Ren, Z., Tan, C., Nunez-Santana, F., Kelly, M. E., Yan, Y., Sun, H., Abdala‐Valencia, H., Yang, W., Wu, Q., et al. (2024) · Journal of Clinical Investigation · doi:10.1172/jci179527 · Cited by 19

Visualization of bone marrow monocyte mobilization using Cx3cr1gfp/+Flt3L−/− reporter mouse by multiphoton intravital microscopy

Evrard, M., Chong, S. Z., Devi, S., Chew, W. K., Lee, B. T. K., Poidinger, M., Ginhoux, F., Tan, S., & Ng, L. G. (2014) · Journal of Leukocyte Biology · doi:10.1189/jlb.1ta0514-274r · Cited by 19

Цукровий діабет і атеросклероз. Роль процесів запалення у патогенезі (огляд літератури)

SOKOLOVA, L. K., PUSHKAREV, V. V., PUSHKAREV, V. V., Kovzun, О. I., & Tronko, M. D. (2017) · INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine) · doi:10.22141/2224-0721.13.7.2017.115747 · Cited by 19

In Utero Administration of Drugs Targeting Microglia Improves the Neurodevelopmental Outcome Following Cytomegalovirus Infection of the Rat Fetal Brain

Cloarec, R., Bauer, Š., Teissier, N., Schaller, F., Luche, H., Courtens, S., Salmi, M., Pauly, V., Bois, E., Pallesi‐Pocachard, E., et al. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00055 · Cited by 19

Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response

Bösl, K., Giambelluca, M. S., Haug, M., Bugge, M., Espevik, T., Kandasamy, R. K., & Bergstrøm, B. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00618 · Cited by 19

Plasmacytoid dendritic cells: origin matters

Manz, M. G. (2018) · Nature Immunology · doi:10.1038/s41590-018-0143-x · Cited by 19

Protective Role of Surfactant Protein-D Against Lung Injury and Oxidative Stress Induced by Nitrogen Mustard

Sunil, V. R., Vayas, K. N., Cervelli, J. A., Ebramova, E. V., Gow, A. J., Goedken, M. J., Malaviya, R., Laskin, J. D., & Laskin, D. L. (2018) · Toxicological Sciences · doi:10.1093/toxsci/kfy188 · Cited by 19

Phospholipid Arachidonic Acid Remodeling During Phagocytosis in Mouse Peritoneal Macrophages

Gil‐de‐Gómez, L., Monge, P., Rodríguez, J. P., Astudillo, A. M., Balboa, M. A., & Balsinde, J. (2020) · Biomedicines · doi:10.3390/biomedicines8080274 · Cited by 20

Hematopoietic stem and progenitor cells are present in healthy gingiva tissue

Krishnan, S., Wemyss, K., Prise, I. E., McClure, F. A., O’Boyle, C., Bridgeman, H. M., Shaw, T. N., Grainger, J. R., & Konkel, J. E. (2021) · The Journal of Experimental Medicine · doi:10.1084/jem.20200737 · Cited by 21

Transitional premonocytes emerge in the periphery for host defense against bacterial infections

Teh, Y. C., Chooi, M. Y., Liu, D., Kwok, I., Lai, G. C., Yong, L. A. O., Ng, M. S. F., Li, J. L. Y., Tan, Y., Evrard, M., et al. (2022) · Science Advances · doi:10.1126/sciadv.abj4641 · Cited by 20

Immuno-metabolism and adipose tissue: The key role of hematopoietic stem cells

Cousin, B., Casteilla, L., Laharrague, P. F., Luche, É., Lorsignol, A., Cuminetti, V., & Paupert, J. (2015) · Biochimie · doi:10.1016/j.biochi.2015.06.012 · Cited by 19

Anti-inflammatory properties of Liposome-encapsulated clodronate or Anti-Ly6G can be modulated by peripheral or central inflammatory markers in carrageenan-induced inflammation model

Mert, T., Sahin, M. A., Şahın, E., & Yaman, S. (2019) · Inflammopharmacology · doi:10.1007/s10787-019-00563-y · Cited by 19

Cell fusion as a driver of metastasis: re-evaluating an old hypothesis in the age of cancer heterogeneity

López‐Collazo, E., & Hurtado‐Navarro, L. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1524781 · Cited by 21

Exosomes and MicroRNAs: key modulators of macrophage polarization in sepsis pathophysiology

Saadh, M. J., Saeed, T. N., Alfarttoosi, K. H., Sanghvi, G. V., Roopashree, R., Thakur, V., Lakshmi, L., Kubaev, A., Taher, W. M., Alwan, M., et al. (2025) · European journal of medical research · doi:10.1186/s40001-025-02561-z · Cited by 19

Deconstructing Immune Microenvironments of Lymphoid Tissues for Reverse Engineering

Witzel, I., Nasser, R. A., Garcia‐Sabaté, A., Sapudom, J., Ma, C., Chen, W., & Teo, J. C. M. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201801126 · Cited by 17

Peripheral Biomarkers of Inflammation in Depression: Evidence from Animal Models and Clinical Studies

Brás, J. P., Pinto, S. F. T., Almeida, M. I., Prata, J., von Doellinger, O., Coelho, R. C., Barbosa, M. A., & Santos, S. G. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9554-7_28 · Cited by 19

HDAC6 Mediates Poly (I:C)-Induced TBK1 and Akt Phosphorylation in Macrophages

Wang, Y., Wang, K., & Fu, J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01776 · Cited by 18

Leishmania donovani Metacyclic Promastigotes Impair Phagosome Properties in Inflammatory Monocytes

Matte, C., Duque, G. A., & Descoteaux, A. (2021) · Infection and Immunity · doi:10.1128/iai.00009-21 · Cited by 17

Mechanisms of Progression and Heterogeneity in Multiple Nodules of Lung Adenocarcinoma

He, Y., Liu, X., Wang, H., Wu, L., Jiang, M., Guo, H., Zhu, J., Wu, S., Sun, H., Chen, S., et al. (2021) · Small Methods · doi:10.1002/smtd.202100082 · Cited by 18

Classical Dichotomy of Macrophages and Alternative Activation Models Proposed with Technological Progress

Wei, Y., Wang, M., Ma, Y., Que, Z., & Yao, D. (2021) · BioMed Research International · doi:10.1155/2021/9910596 · Cited by 22

Characterization of Zymosan-Modulated Neutrophils With Neuroregenerative Properties

Jerome, A. D., Atkinson, J., Moffatt, A. M., Sepeda, J. A., Segal, B. M., & Sas, A. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.912193 · Cited by 18

Identifying Hyperreflective Foci in Diabetic Retinopathy via VEGF-Induced Local Self-Renewal of CX3CR1+ Vitreous Resident Macrophages

Yamaguchi, M., Nakao, S., Wada, I., Matoba, T., Arima, M., Kaizu, Y., Shirane, M., Ishikawa, K., Nakama, T., Murakami, Y., et al. (2022) · Diabetes · doi:10.2337/db21-0247 · Cited by 19

Innovative immune mechanisms and antioxidative therapies of intervertebral disc degeneration

Wei, B., Zhao, Y., Li, W., Zhang, S., Yan, M., Hu, Z., & Gao, B. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.1023877 · Cited by 18

Regulatory mechanism of macrophage polarization based on Hippo pathway

Liu, Y., An, Y., Li, G., & Wang, S. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1279591 · Cited by 20

A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection

Fontana, M. F., Baccarella, A., Craft, J. F., Boyle, M. J., McIntyre, T. I., Wood, M. D., Thorn, K. S., Anidi, C. M., Bayat, A., Chung, M. R., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162132 · Cited by 18

The Role of Phagocytes and NETs in Dermatophytosis

Yoshikawa, F. S. Y., & de Almeida, S. R. (2016) · Mycopathologia · doi:10.1007/s11046-016-0069-5 · Cited by 18

Tumor Associated Macrophages as Therapeutic Targets for Breast Cancer

Lao, L., Fan, S., & Song, E. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-6020-5_16 · Cited by 19

Expansion of a Population of Large Monocytes (Atypical Monocytes) in Peripheral Blood of Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Diseases

Yang, J., Qiao, M., Li, Y., Hu, G., Song, C., Xue, L., Bai, H., Yang, J., & Yang, X. (2018) · Mediators of Inflammation · doi:10.1155/2018/9031452 · Cited by 20

Crosstalk Between Cardiac Cells and Macrophages Postmyocardial Infarction: Insights from In Vitro Studies

Hitscherich, P. G., & Lee, E. J. (2020) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2020.0198 · Cited by 19

Yellow fever virus vaccination: an emblematic model to elucidate robust human immune responses

Bovay, A., Marraco, S. A. F., & Speiser, D. E. (2021) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2021.1891752 · Cited by 19

Single-Cell Transcriptomics Reveals the Cellular Heterogeneity of Cardiovascular Diseases

Fu, M., & Song, J. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.643519 · Cited by 18

Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem Cells

Mostina, M., Sun, J., Sim, S. L., Ahmed, I. A., Souza‐Fonesca‐Guimaraes, F., Wolvetang, E. J., Brown, J., Kumari, S., Khosrotehrani, K., & Shafiee, A. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202502108 · Cited by 17

Cholesterol sensing and metabolic adaptation in tissue immunity

Dang, E. V., & Reboldi, A. (2024) · Trends in Immunology · doi:10.1016/j.it.2024.09.013 · Cited by 17

Nanoparticles with reprogramming of mitochondrial respiratory chain complex and epigenetic modifications functions for osteoporosis treatment

Liu, Y., Xin, L., Wang, S., Tan, J., Zhu, X., Chen, X., Song, J., Chen, T., & Zhai, Q. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123468 · Cited by 18

Fate mapping of peripherally-derived macrophages after traumatic brain injury in mice reveals a long-lasting population with a distinct transcriptomic signature

Paladini, M. S., Yang, B. A., Torkenczy, K. A., Frias, E. S., Feng, X., Krukowski, K., Sit, R. V., Morri, M., Lam, W., Pedoia, V., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63952-8 · Cited by 22

Mind the Map: Technology Shapes the Myeloid Cell Space

Günther, P. S., & Schultze, J. L. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02287 · Cited by 17

Role of NR4A family members in myeloid cells and leukemia

Boulet, S., Le Corre, L., Odagiu, L., & Labrecque, N. (2022) · Current Research in Immunology · doi:10.1016/j.crimmu.2022.02.001 · Cited by 17

Identification of clinical heterogeneity and construction of a novel subtype predictive model in patients with ankylosing spondylitis: An unsupervised machine learning study

Sun, X., Zhou, C., Zhu, J., Wu, S., Liang, T., Jiang, J., Chen, J., Chen, T., Huang, S. S., Chen, L., et al. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.109879 · Cited by 17

Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption

Zhu, L., Tang, Y., Li, X.-Y., Kerk, S. A., Lyssiotis, C. A., Sun, X., Wang, Z., Cho, J., Ma, J., & Weiss, S. J. (2023) · The Journal of Cell Biology · doi:10.1083/jcb.202206121 · Cited by 18

The Pivotal Role of Macrophages in the Pathogenesis of Pancreatic Diseases

Ryu, S., & Lee, E. K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115765 · Cited by 19

Meningeal lymphatic vessel crosstalk with central nervous system immune cells in aging and neurodegenerative diseases

Gao, M., Wang, X., Su, S., Feng, W., Lai, Y., Huang, K., Cao, D., & Wang, Q. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-01595 · Cited by 18

Depletion of CD11c+ cells in the CD11c.DTR model drives expansion of unique CD64+ Ly6C+ monocytes that are poised to release TNF‐α

Sivakumaran, S., Henderson, S. R., Ward, S., Sousa, P. S. E., Manzo, T., Zhang, L., Conlan, T., Means, T. K., D’Aveni, M., Hermine, O., et al. (2015) · European Journal of Immunology · doi:10.1002/eji.201545789 · Cited by 16

Alterations in Monocyte Phenotypes and Functions after a Hip Fracture in Elderly Individuals: A 6-Month Longitudinal Study

Baëhl, S., Garneau, H., Lorrain, D., Viens, I., Svotelis, A., Lord, J. M., Cabana, F., Larbi, A., Dupuis, G., & Fülöp, T. (2016) · Gerontology · doi:10.1159/000443142 · Cited by 19

Reprogramming of histone methylation controls the differentiation of monocytes into macrophages

Zheng, Q., Wang, H., Wang, Z., Liu, J., Zhang, Q., Zhang, L., Lu, Y., You, H., & Jin, G. (2017) · FEBS Journal · doi:10.1111/febs.14060 · Cited by 17

Association of Increased F4/80high Macrophages With Suppression of Serum‐Transfer Arthritis in Mice With Reduced FLIP in Myeloid Cells

Huang, Q., Birkett, R., Doyle, R., Haines, G. K., Perlman, H., Shi, B., Homan, P., Xing, L., & Pope, R. M. (2017) · Arthritis & Rheumatology · doi:10.1002/art.40151 · Cited by 17

Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672

Yang, M. G., Xiao, Z., Cherney, R. J., Tebben, A. J., Batt, D. G., Brown, G. D., Chen, J., Cvijic, M. E., Dabros, M., Duncia, J. V., et al. (2019) · ACS Medicinal Chemistry Letters · doi:10.1021/acsmedchemlett.8b00439 · Cited by 17

Neuroimmune interactions in Alzheimer's disease—New frontier with old challenges?

Prokop, S., Lee, V. M. ‐., & Trojanowski, J. Q. (2019) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2019.10.002 · Cited by 17

Angiotensin II Type 2 Receptor Modulates Synovial Macrophage Polarization by Inhibiting GRK2 Membrane Translocation in a Rat Model of Collagen-Induced Arthritis

Wang, X., Tu, J., Ji, J., Zhang, Q., Liu, Q., Körner, H., Wu, J., Wu, H., & Wei, W. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.2000561 · Cited by 17

IL-27 Negatively Regulates Tip-DC Development during Infection

Liu, G., Abas, O. M., Fu, Y., Chen, Y., Strickland, A. B., Sun, D., & Shi, M. (2021) · mBio · doi:10.1128/mbio.03385-20 · Cited by 18

The origins and homeostasis of monocytes and tissue‐resident macrophages in physiological situation

Zhao, Y., Zou, W., Du, J., & Zhao, Y. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26461 · Cited by 190

Tissue-Resident Macrophage Ontogeny and Homeostasis

Ginhoux, F., & Guilliams, M. (2016) · Immunity · doi:10.1016/j.immuni.2016.02.024 · Cited by 1,884

The Mononuclear Phagocyte System: The Relationship between Monocytes and Macrophages

Hume, D. A., Irvine, K. M., & Pridans, C. (2018) · Trends in Immunology · doi:10.1016/j.it.2018.11.007 · Cited by 270

Physiological roles of macrophages

Gordon, S., & Martínez‐Pomares, L. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1945-7 · Cited by 242

Origin, development, and homeostasis of tissue‐resident macrophages

Haldar, M., & MURPHY, K. M. M. (2014) · Immunological Reviews · doi:10.1111/imr.12215 · Cited by 125