The RSK family of kinases: emerging roles in cellular signalling

AKT/PKB signaling: navigating downstream

Manning, B. D., & Cantley, L. C. (2007) · Cell · doi:10.1016/j.cell.2007.06.009 · Cited by 6,115

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

Roberts, P. J., & Der, C. J. (2007) · Oncogene · doi:10.1038/sj.onc.1210422 · Cited by 2,788

ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions

Roux, P. P., & Blenis, J. (2004) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.68.2.320-344.2004 · Cited by 2,540

The selectivity of protein kinase inhibitors: a further update

Bain, J., Plater, L., Elliott, M., Shpiro, N., Hastie, C. J., McLauchlan, H., Klevernic, I. V., Arthur, J. S. C., Alessi, D. R., & Cohen, P. (2007) · Biochemical Journal · doi:10.1042/bj20070797 · Cited by 2,522

Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization

Diehl, J. A., Cheng, M., Roussel, M. F., & Sherr, C. J. (1998) · Genes & Development · doi:10.1101/gad.12.22.3499 · Cited by 2,130

Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms

Bonni, A., Brunet, A., West, A. E., Datta, S. R., Takasu, M. A., & Greenberg, M. E. (1999) · Science · doi:10.1126/science.286.5443.1358 · Cited by 1,908

The renaissance of GSK3

Cohen, P., & Frame, S. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35096075 · Cited by 1,493

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stabilityPreprint

Sears, R. C., Nuckolls, F., Haura, E. B., Taya, Y., Tamai, K., & Nevins, J. R. (2000) · Genes & Development · doi:10.1101/gad.836800 · Cited by 1,411

Gene silencing in mammals by small interfering RNAs

McManus, M. T., & Sharp, P. A. (2002) · Nature Reviews Genetics · doi:10.1038/nrg908 · Cited by 1,400

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

Fingar, D. C., & Blenis, J. (2004) · Oncogene · doi:10.1038/sj.onc.1207542 · Cited by 1,264

Alcohol Intoxication Following Muscle Contraction in Mice Decreases Muscle Protein Synthesis But Not mTOR Signal Transduction

Steiner, J. L., & Lang, C. H. (2015) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12600 · Cited by 30

Targeting RSK2 in human malignancies

Kang, S., & Chen, J. (2010) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2010.531013 · Cited by 31

Gossypin inhibits gastric cancer growth by direct targeting of AURKA and RSK2

Wang, L., Wang, X., Chen, H., Zu, X., Ma, F., Liu, K., Bode, A. M., Dong, Z., & Kim, D. J. (2018) · Phytotherapy Research · doi:10.1002/ptr.6253 · Cited by 30

Substituted indolin-2-ones as p90 ribosomal S6 protein kinase 2 (RSK2) inhibitors: Molecular docking simulation and structure–activity relationship analysis

Zhong, Y., Xue, M., Zhao, X. Z., Yuan, J. L., Liu, X., Huang, J. Y., Zhao, Z., Li, H., & Xu, Y. F. (2013) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2013.01.047 · Cited by 30

Mutation of the 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Substrate-Docking Site in the Developing Brain Causes Microcephaly with Abnormal Brain Morphogenesis Independently of Akt, Leading to Impaired Cognition and Disruptive Behaviors

Cordón-Barris, L., Pascual-Guiral, S., Yang, S., Giménez‐Llort, L., Lope‐Piedrafita, S., Niemeyer, C., Claro, E., Lizcano, J. M., & Bayascas, J. R. (2016) · Molecular and Cellular Biology · doi:10.1128/mcb.00230-16 · Cited by 31

Scaffolding during the cell cycle by A-kinase anchoring proteins

Han, B., Poppinga, W. J., & Schmidt, M. (2015) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-015-1718-0 · Cited by 29

RSK2 activity mediates glioblastoma invasiveness and is a potential target for new therapeutics

Sulzmaier, F. J., Young‐Robbins, S. S., Jiang, P., Geerts, D., Prechtl, A. M., Matter, M. L., Kesari, S., & Ramos, J. W. (2016) · Oncotarget · doi:10.18632/oncotarget.13084 · Cited by 29

Oxytocin: its role in benign prostatic hyperplasia via the ERK pathway

Xu, H., Fu, S., Chen, Y., Chen, Q., Gu, M., Liu, C., Qiao, Z., Zhou, J., & Wang, Z. (2017) · Clinical Science · doi:10.1042/cs20170030 · Cited by 29

Effect ofPorphyromonas gingivalisinfection in the placenta and umbilical cord in pregnant mice with low birth weight

Udagawa, S., Katagiri, S., Maekawa, S., Takeuchi, Y., Komazaki, R., Ohtsu, A., Sasaki, N., Shiba, T., Watanabe, K., Ishihara, K., et al. (2018) · Acta Odontologica Scandinavica · doi:10.1080/00016357.2018.1426876 · Cited by 29

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2

Wang, L., Zhang, Y., Liu, K., Chen, H., Yang, R., Ma, X., Kim, H.-G., Bode, A. M., Kim, D. J., & Dong, Z. (2018) · Oncotarget · doi:10.18632/oncotarget.24409 · Cited by 29

New insights into the regulation and function of serine/threonine kinases in T lymphocytes

Matthews, S. A., & Cantrell, D. A. (2009) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00759.x · Cited by 29

Activation of RSK by phosphomimetic substitution in the activation loop is prevented by structural constraints

Somale, D., Nardo, G. D., di Blasio, L., Puliafito, A., Vara-Messler, M., Chiaverina, G., Palmiero, M., Monica, V., Gilardi, G., Primo, L., et al. (2020) · Scientific Reports · doi:10.1038/s41598-019-56937-3 · Cited by 28

Regulation of NHE3 by lysophosphatidic acid is mediated by phosphorylation of NHE3 by RSK2

No, Y. R., He, P., Yoo, B. K., & Yun, C. C. (2015) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00067.2015 · Cited by 28

RSK4 inhibition results in bypass of stress-induced and oncogene-induced senescence

López-Vicente, L., Pons, B., Coch, L., Teixidó, C., Hernández‐Losa, J., Armengol, G., & y Cajal, S. R. (2011) · Carcinogenesis · doi:10.1093/carcin/bgr003 · Cited by 28

SH3P2 is a negative regulator of cell motility whose function is inhibited by ribosomal S6 kinase-mediated phosphorylation

Tanimura, S., Hashizume, J., 黒崎由希子, Sei, K., Gotoh, A., Ohtake, R., Kawano, M., Watanabe, K., & Kohno, M. (2011) · Genes to Cells · doi:10.1111/j.1365-2443.2011.01503.x · Cited by 28

RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation

Yao, K., Lee, S., Peng, C., Lim, D. Y., Yamamoto, H., Ryu, J., Lim, T., Chen, H., Jin, G., Zhao, Z., et al. (2018) · Oncogene · doi:10.1038/s41388-018-0167-6 · Cited by 27

Biology using engineering tools

Birtwistle, M. R., & Kölch, W. (2011) · Cell Cycle · doi:10.4161/cc.10.13.16245 · Cited by 27

Thyroid hormone receptor β1 domains responsible for the antagonism with the ras oncogene: role of corepressors

Garcı́a-Silva, S., Martínez-Iglesias, O. A., Ruiz-Llorente, L., & Aranda, A. (2010) · Oncogene · doi:10.1038/onc.2010.464 · Cited by 27

Gingerenone A Sensitizes the Insulin Receptor and Increases Glucose Uptake by Inhibiting the Activity of p70 S6 Kinase

Chen, J., Sun, J. F., Prinz, R. A., Li, Y., & Xu, X. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201800709 · Cited by 27

Mnk1 and 2 Are Dispensable for T Cell Development and Activation but Important for the Pathogenesis of Experimental Autoimmune Encephalomyelitis

Gorentla, B. K., Krishna, S., Shin, J., Inoue, M., Shinohara, M. L., Grayson, J. M., Fukunaga, R., & Zhong, X.-P. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1200026 · Cited by 27

p90RSK activation contributes to cerebral ischemic damage via phosphorylation of Na+/H+ exchanger isoform 1

Manhas, N., Shi, Y., Taunton, J., & Sun, D. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06868.x · Cited by 27

Localization and retention of p90 ribosomal S6 kinase 1 in the nucleus: implications for its function

Gao, X., Chaturvedi, D., & Patel, T. B. (2011) · Molecular Biology of the Cell · doi:10.1091/mbc.e11-07-0658 · Cited by 26

Expression and phosphorylation of the AS160_v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma

Cheng, J. C., McBrayer, S. K., Coarfa, C., Dalva-Aydemir, S., Gunaratne, P. H., Carpten, J. D., Keats, J. J., Rosen, S. T., & Shanmugam, M. (2013) · Cancer & Metabolism · doi:10.1186/2049-3002-1-14 · Cited by 26

Gating of the Mitochondrial Permeability Transition Pore by Long Chain Fatty Acyl Analogs in Vivo

Samovski, D., Kalderon, B., Yehuda‐Shnaidman, E., & Bar‐Tana, J. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.080416 · Cited by 26

Inhibition of p90 ribosomal S6 kinase attenuates cell migration and proliferation of the human lung adenocarcinoma through phospho-GSK-3β and osteopontin

Abdulrahman, N., Jaballah, M. Y., Poomakkoth, N., Riaz, S., Abdelaziz, S., Issa, A., & Mraiche, F. (2016) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-016-2727-9 · Cited by 26

Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation

Oblinger, J. L., Burns, S. S., Huang, J., Li, P., Ren, Y., Shen, R. Z., Kinghorn, A. D., Welling, D. B., & Chang, L. (2017) · Experimental Neurology · doi:10.1016/j.expneurol.2017.06.015 · Cited by 26

Extracellular Activities of Aminoacyl-tRNA Synthetases: New Mediators for Cell–Cell Communication

Son, S. H., Park, M., & Kim, S. (2013) · Topics in current chemistry · doi:10.1007/128_2013_476 · Cited by 26

Insulin Activates RSK (p90 Ribosomal S6 Kinase) to Trigger a New Negative Feedback Loop That Regulates Insulin Signaling for Glucose Metabolism

Smadja-Lamère, N., Shum, M., Déléris, P., Roux, P. P., Abe, J., & Marette, A. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.474148 · Cited by 29

IFN-γ–inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5

Saleiro, D., Blyth, G. T., Kościuczuk, E. M., Ozark, P. A., Majchrzak-Kita, B., Arslan, A. D., Fischietti, M., Reddy, N. K., Horvath, C. M., Davis, R. J., et al. (2018) · Science Signaling · doi:10.1126/scisignal.aap9921 · Cited by 25

The ribosomal protein S6 kinase alpha-1 (RPS6KA1) induces resistance to venetoclax/azacitidine in acute myeloid leukemia

Weidenauer, K., Schmidt, C., Rohde, C., Pauli, C., Blank, M. F., Heid, D., Waclawiczek, A., Corbacioglu, A., Göllner, S., Lotze, M., et al. (2023) · Leukemia · doi:10.1038/s41375-023-01951-8 · Cited by 26

Recently Identified Biomarkers That Promote Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma

Walk, E. L., & Weed, S. A. (2011) · Cancers · doi:10.3390/cancers3010747 · Cited by 25

De Novo Synthesis and Biological Evaluation of C6″-Substituted C4″-Amide Analogues of SL0101

Mrozowski, R. M., Sandusky, Z. M., Vemula, R., Wu, B., Zhang, Q., Lannigan, D. A., & O'Doherty, G. A. (2014) · Organic Letters · doi:10.1021/ol503012k · Cited by 25

RSK2 signaling in brain habenula contributes to place aversion learningPreprint

Darcq, E., Koebel, P., Boca, C. D., Pannetier, S., Kirstetter, A.-S., Garnier, J., Hanauer, A., Befort, K., & Kieffer, B. L. (2011) · Learning & Memory · doi:10.1101/lm.2221011 · Cited by 25

Bioactive Materials in Vital Pulp Therapy: Promoting Dental Pulp Repair Through Inflammation Modulation

Qiao, L., Zheng, X., Xie, C., Wang, Y., Ye, L., Zhao, J., & Liu, J. (2025) · Biomolecules · doi:10.3390/biom15020258 · Cited by 24

Discovery of potential RSK1 inhibitors for cancer therapy using virtual screening, molecular docking, molecular dynamics simulation, and MM/GBSA calculations

Kalın, S., & Önder, F. C. (2023) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2023.2291830 · Cited by 24

EGFR and PKC are involved in the activation of ERK1/2 and p90 RSK and the subsequent proliferation of SNU-407 colon cancer cells by muscarinic acetylcholine receptors

Park, Y., & Cho, N. J. (2012) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-012-1410-z · Cited by 24

ERK and RSK regulate distinct steps of a cellular program that induces transition from multicellular epithelium to single cell phenotype

Čáslavský, J., Klímová, Z., & Vomastek, T. (2013) · Cellular Signalling · doi:10.1016/j.cellsig.2013.08.024 · Cited by 24

Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity

Xifró, X., Anglada‐Huguet, M., Rué, L., Saavedra, A., Pérez‐Navarro, E., & Alberch, J. (2011) · Molecular Neurodegeneration · doi:10.1186/1750-1326-6-74 · Cited by 24

p90RSKs mediate the activation of ribosomal RNA synthesis by the hypertrophic agonist phenylephrine in adult cardiomyocytes

Zhang, Z., Liu, R., Townsend, P. A., & Proud, C. G. (2013) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2013.03.006 · Cited by 25

Antitumor effects of BI-D1870 on human oral squamous cell carcinoma

Chiu, C., Bai, L., Kapuriya, N. P., Peng, S., Wu, C.-Y., Sargeant, A. M., Chen, M. Y., & Weng, J. (2013) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-013-2349-9 · Cited by 24

Arf6 promotes cell proliferation via the PLD‐mTORC1 and p38MAPK pathways

Knizhnik, A. V., Kovaleva, O. V., Komelkov, A. V., Trukhanova, L. S., Александровна, Р. В., Zborovskaya, I. B., & Tchevkina, E. M. (2011) · Journal of Cellular Biochemistry · doi:10.1002/jcb.23362 · Cited by 25

Mechanistic target of rapamycin complex 1 is an essential mediator of metabolic and mitogenic effects of fibroblast growth factor 19 in hepatoma cells

Wan, Z. Y., Tian, J. S., Tan, H. W. S., Chow, A. L., Sim, A. Y. L., Ban, K. H.-K., & Long, Y. C. (2016) · Hepatology · doi:10.1002/hep.28639 · Cited by 25

RSK activation via ERK modulates human colon cancer cells response to PTHrP

Calvo, N., Carriere, P., Martín, M. J., & Gentili, C. (2017) · Journal of Molecular Endocrinology · doi:10.1530/jme-16-0216 · Cited by 24

Single-cell quantification of the concentrations and dissociation constants of endogenous proteins

Komatsubara, A. T., Goto, Y., Kondo, Y., Matsuda, M., & Aoki, K. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.007685 · Cited by 24

Aberrant expression of RSK1 characterizes high‐grade gliomas with immune infiltration

Hajj, G. N. M., da Silva, F. F., de Bellis, B., Lupinacci, F. C. S., Bellato, H. M., Cruz, J. R., Segundo, C. N. C., Faquini, I. V., Torres, L. C., Sanematsu, P., et al. (2019) · Molecular Oncology · doi:10.1002/1878-0261.12595 · Cited by 24

In vitro activity of dietary flavonol congeners against human cancer cell lines

Tsimplouli, C., Demetzos, C., Hadzopoulou‐Cladaras, M., Pantazis, P., & DIMAS, K. S. (2011) · European Journal of Nutrition · doi:10.1007/s00394-011-0204-5 · Cited by 24

Current activities of the Yersinia effector protein YopM

Höfling, S., Grabowski, B., Norkowski, S., Schmidt, M. A., & Rüter, C. (2015) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2015.03.009 · Cited by 24

Prominent roles of ribosomal S6 kinase 4 (RSK4) in cancer

Xu, J., Jia, Q., Zhang, Y., Yuan, Y., Xu, T., Yu, K., Chai, J., Wang, K., Chen, L., Xiao, T. L., et al. (2021) · Pathology - Research and Practice · doi:10.1016/j.prp.2021.153374 · Cited by 23

RSK1 promotes mammalian axon regeneration by inducing the synthesis of regeneration-related proteins

Mao, S., Chen, Y., Feng, W., Zhou, S., Jiang, C., Zhang, J., Liu, X., Qian, T., Liu, K., Wang, Y., et al. (2022) · PLoS Biology · doi:10.1371/journal.pbio.3001653 · Cited by 23

Kinase analysis in alcoholic hepatitis identifies p90RSK as a potential mediator of liver fibrogenesis

Morales‐Ibanez, O., Affò, S., Rodrigo‐Torres, D., Blaya, D., Millán, C., Coll, M., Perea, L., Òdena, G., Knorpp, T., Templin, M. F., et al. (2015) · Gut · doi:10.1136/gutjnl-2014-307979 · Cited by 23

Protein Phosphorylation as a Key Mechanism of mTORC1/2 Signaling Pathways

Tchevkina, E. M., & Komelkov, A. V. (2012) · InTech eBooks · doi:10.5772/48274 · Cited by 26

RSK4 knockdown promotes proliferation, migration and metastasis of human breast adenocarcinoma cells

Zhu, J. Y., Li, Q., Liu, J., Wei, W., Yang, H., & Tang, W. D. (2015) · Oncology Reports · doi:10.3892/or.2015.4291 · Cited by 23

The mechanism and function of mitogen-activated protein kinase activation by ARF1

Zhou, F., Dong, C., Davis, J., Wu, W. H., Surrao, K., & Wu, G. (2015) · Cellular Signalling · doi:10.1016/j.cellsig.2015.06.007 · Cited by 23

Synaptically driven phosphorylation of ribosomal protein S6 is differentially regulated at active synapses versus dendrites and cell bodies by MAPK and PI3K/mTOR signaling pathwaysPreprint

Pirbhoy, P. S., Farris, S., & Steward, O. (2017) · Learning & Memory · doi:10.1101/lm.044974.117 · Cited by 23

Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration

Czaplińska, D., Turczyk, L., Grudowska, A., Mieszkowska, M., Lipińska, A. D., Składanowski, A. C., Zaczek, A. J., Romańska, H., & Sądej, R. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.06.022 · Cited by 22

Deletion of cyclooxygenase-2 inhibits K-ras-induced lung carcinogenesis

Pan, Y., Jiang, Y., Tan, L., Ravoori, M. K., Gagea, M., Kundra, V., Fischer, S. M., & Yang, P. (2015) · Oncotarget · doi:10.18632/oncotarget.5558 · Cited by 22

Cellular stress induces non-canonical activation of the receptor tyrosine kinase EphA2 through the p38-MK2-RSK signaling pathway

Zhou, Y., Oki, R., Tanaka, A., Song, L., Takashima, A., Hamada, N., Yokoyama, S., Yano, S., & Sakurai, H. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.104699 · Cited by 22

RSK3: A regulator of pathological cardiac remodeling

Martinez, E. C., Passariello, C. L., Li, J., Matheson, C. J., Dodge‐Kafka, K. L., Reigan, P., & Kapiloff, M. S. (2015) · IUBMB Life · doi:10.1002/iub.1383 · Cited by 22

Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation

Shiryaev, A., Dumitriu, G., & Moens, U. L. (2011) · Journal of Molecular Signaling · doi:10.1186/1750-2187-6-4 · Cited by 22

Aconitase Regulation of Erythropoiesis Correlates with a Novel Licensing Function in Erythropoietin-Induced ERK Signaling

Talbot, A.-L., Bullock, G. C., Delehanty, L. L., Sattler, M., Zhao, Z. J., & Goldfarb, A. N. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023850 · Cited by 23

Involvement of ERK–RSK cascade in phenylephrine-induced phosphorylation of GATA4

Li, T., Liu, Z., Hu, X., Ma, K., & Zhou, C. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2011.12.009 · Cited by 23

Downregulation of RSK2 influences the biological activities of human osteosarcoma cells through inactivating AKT/mTOR signaling pathways

Qiu, Q., Jiang, J., Lin, L., Cheng, S., Xin, D., Jiang, W., Shen, J., & Hu, Z. (2016) · International Journal of Oncology · doi:10.3892/ijo.2016.3481 · Cited by 22

Discovery of a novel dual-target inhibitor against RSK1 and MSK2 to suppress growth of human colon cancer

Jin, G., Yan, M., Liu, K., Yao, K., Chen, H., Zhang, C., Yi, Y., Reddy, K., Gorja, D. R., Laster, K. V., et al. (2020) · Oncogene · doi:10.1038/s41388-020-01467-w · Cited by 22

TGFβ enforces activation of eukaryotic elongation factor‐2 (eEF2) via inactivation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy

Das, F., Ghosh‐Choudhury, N., Kasinath, B. S., & Choudhury, G. G. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.09.010 · Cited by 22

ITD‐ and FL‐induced FLT3 signal transduction leads to increased C/EBPβ‐LIP expression and LIP/LAP ratio by different signalling modules

Haas, S. C., Huber, R., Gutsch, R., Kandemir, J. D., Cappello, C., Krauter, J., Duyster, J., Ganser, A., & Brand, K. (2009) · British Journal of Haematology · doi:10.1111/j.1365-2141.2009.08012.x · Cited by 22

Mitogen‐ and stress‐activated protein kinase 1 modulates photic entrainment of the suprachiasmatic circadian clock

Cao, R., Butcher, G. Q., Karelina, K., Arthur, J. S. C., & Obrietan, K. H. (2012) · European Journal of Neuroscience · doi:10.1111/ejn.12028 · Cited by 22

Major Physiological Signaling Pathways in the Regulation of Cell Proliferation and Survival

Tang, H., & Xue, G. (2017) · Handbook of experimental pharmacology · doi:10.1007/164_2017_4 · Cited by 22

RSK1 and RSK2 serine/threonine kinases regulate different transcription programs in cancer

Yang, W. S., Caliva, M. J., Khadka, V. S., Tiirikainen, M., Matter, M. L., Deng, Y., & Ramos, J. W. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1015665 · Cited by 21

Deciphering the complete human-monkeypox virus interactome: Identifying immune responses and potential drug targets

Kataria, R., Kaur, S., & Kaundal, R. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1116988 · Cited by 21

Glycogen Synthase Kinase 3 Regulates Cell Death and Survival Signaling in Tumor Cells under Redox Stress

Venè, R., Cardinali, B., Arena, G., Ferrari, N., Benelli, R., Minghelli, S., Poggi, A. D., Noonan, D. M., Albini, A., & Tosetti, F. (2014) · Neoplasia · doi:10.1016/j.neo.2014.07.012 · Cited by 21

CCAAT-enhancer-binding protein beta activation of MMP-1 gene expression in SW1353 Cells: Independent roles of extracellular signal-regulated and p90/ribosomal S6 kinases

Petrella, B. L., Armstrong, D. A., & Vincenti, M. P. (2011) · Journal of Cellular Physiology · doi:10.1002/jcp.22693 · Cited by 21

Aberrantly activated anti‐apoptotic signalling mechanisms in chronic lymphocytic leukaemia cells: clues to the identification of novel therapeutic targets

Wickremasinghe, R. G., Prentice, A. G., & Steele, A. J. (2011) · British Journal of Haematology · doi:10.1111/j.1365-2141.2011.08676.x · Cited by 21

Frequent epigenetic inactivation of RSK4 by promoter methylation in cancerous and non-cancerous tissues of breast cancer

Li, Q., Jiang, Y., Wei, W., Ji, Y., Gao, H., & Liu, J. (2013) · Medical Oncology · doi:10.1007/s12032-013-0793-3 · Cited by 21

MAPKs in development: insights from Dictyostelium signaling pathways

Hadwiger, J. A., & Nguyen, H. (2011) · BioMolecular Concepts · doi:10.1515/bmc.2011.004 · Cited by 24

Transfer-RNA-mediated enhancement of ribosomal proteins S6 kinases signaling for cell proliferation

Kwon, N. H., Lee, M. R., Kong, J., Park, S. K., Hwang, B. J., Kim, B. G., Lee, E.-S., Moon, H., & Kim, S. (2017) · RNA Biology · doi:10.1080/15476286.2017.1356563 · Cited by 21

Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1

Kolsi, L. E., Leal, A. S., Yli‐Kauhaluoma, J. T., Liby, K. T., & Moreira, V. M. (2018) · Scientific Reports · doi:10.1038/s41598-018-34131-1 · Cited by 21

Bioorthogonal Engineering of Bacterial Effectors for Spatial–Temporal Modulation of Cell Signaling

Zhao, J., Liu, Y., Lin, F., Wang, W., Yang, S., Ge, Y., & Chen, P. R. (2018) · ACS Central Science · doi:10.1021/acscentsci.8b00751 · Cited by 21

PTEN Blocking Stimulates Corticospinal and Raphespinal Axonal Regeneration and Promotes Functional Recovery After Spinal Cord Injury

Bhowmick, S., & Muneer, P. M. A. (2020) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlaa147 · Cited by 21

A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host

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