The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Membrane budding and scission by the ESCRT machinery: it's all in the neck
Open accessAbstract
The endosomal sorting complexes required for transport (ESCRTs) catalyse one of the most unusual membrane remodelling events in cell biology. ESCRT-I and ESCRT-II direct membrane budding away from the cytosol by stabilizing bud necks without coating the buds and without being consumed in the buds. ESCRT-III cleaves the bud necks from their cytosolic faces. ESCRT-III-mediated membrane neck cleavage is crucial for many processes, including the biogenesis of multivesicular bodies, viral budding, cytokinesis and, probably, autophagy. Recent studies of ultrastructures induced by ESCRT-III overexpression in cells and the in vitro reconstitution of the budding and scission reactions have led to breakthroughs in understanding these remarkable membrane reactions.
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Citations
Cites
Autophagy fights disease through cellular self-digestion
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Molecular mechanism of multivesicular body biogenesis by ESCRT complexes
Wollert, T., & Hurley, J. H. (2010) · Nature · doi:10.1038/nature08849 · Cited by 804
Self-citationBiogenesis and Function of Multivesicular Bodies
Piper, R. C., & Katzmann, D. J. (2007) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.23.090506.123319 · Cited by 771
Parallels Between Cytokinesis and Retroviral Budding: A Role for the ESCRT Machinery
Carlton, J. G., & Martin-Serrano, J. (2007) · Science · doi:10.1126/science.1143422 · Cited by 764
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis
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Plasma membrane deformation by circular arrays of ESCRT-III protein filaments
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Self-citationTeo, H., Gill, D. J., Sun, J., Perisic, O., Veprintsev, D. B., Vallis, Y., Emr, S. D., & Williams, R. L. (2006) · Cell · doi:10.1016/j.cell.2006.01.047 · Cited by 242
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Structural Basis for Endosomal Targeting by the Bro1 Domain
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Self-citation
Cited by
Regulation of immune responses by extracellular vesicles
Robbins, P. D., & Morelli, A. E. (2014) · Nature Reviews Immunology · doi:10.1038/nri3622 · Cited by 2,260
Syndecan–syntenin–ALIX regulates the biogenesis of exosomes
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“In this regard, it is not surprising that certain proteins involved in EV formation also participate in cytokinesis [40].”
Exosomes: key players in cancer and potential therapeutic strategy
Dai, J., Su, Y., Zhong, S., Cong, L., Liu, B., Yang, J., Tao, Y., He, Z., Chen, C., & Jiang, Y. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00261-0 · Cited by 1,186
Exosomes and Ectosomes in Intercellular Communication
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Metadata
- Authors
- Hurley, J. H., & Hanson, P. I.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2010-06-30
- Volume
- 11
- Issue
- 8
- Pages
- 556-566
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W1980798766
- Cited by
- 755
- References
- 13
- FWCI
- 4.04
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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