A day in the life of the spliceosome

Expansion of the eukaryotic proteome by alternative splicing

Nilsen, T. W., & Graveley, B. R. (2010) · Nature · doi:10.1038/nature08909 · Cited by 2,270

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

Fornerod, M. W. J., Ohno, M., Yoshida, M., & Mattaj, I. W. (1997) · Cell · doi:10.1016/s0092-8674(00)80371-2 · Cited by 2,086

Frequent pathway mutations of splicing machinery in myelodysplasia

Yoshida, K., Sanada, M., Shiraishi, Y., Nowak, D., Nagata, Y., Yamamoto, R., Sato, Y., Sato-Otsubo, A., Kon, A., Nagasaki, M., et al. (2011) · Nature · doi:10.1038/nature10496 · Cited by 2,029

Spliceosome Structure and Function

Will, C. L., & Luhrmann, R. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003707 · Cited by 1,829

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

Lorson, C. L., Hahnen, E., Androphy, E. J., & Wirth, B. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.11.6307 · Cited by 1,536

Spliced segments at the 5′ terminus of adenovirus 2 late mRNA

Berget, S. M., Moore, C. L., & Sharp, P. A. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.8.3171 · Cited by 1,483

Understanding alternative splicing: towards a cellular code

Matlin, A. J., Clark, F., & Smith, C. W. J. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1645 · Cited by 1,299

An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA

Chow, L. T., Gelinas, R. E., Broker, T. R., & Roberts, R. J. (1977) · Cell · doi:10.1016/0092-8674(77)90180-5 · Cited by 1,234

Are snRNPs involved in splicing?

Lerner, M. R., Boyle, J. A., Mount, S. M., Wolin, S. L., & STEITZ, J. A. (1980) · Nature · doi:10.1038/283220a0 · Cited by 1,192

Splicing regulation: From a parts list of regulatory elements to an integrated splicing code

Wang, Z., & Burge, C. B. (2008) · RNA · doi:10.1261/rna.876308 · Cited by 1,127

The Role of Noncoding RNA Pseudouridylation in Nuclear Gene Expression Events

Zhao, Y., Dunker, W., Yu, Y., & Karijolich, J. J. (2018) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2018.00008 · Cited by 50

Insights into the role of alternative splicing in plant temperature response

Dikaya, V., Arbi, N. E., Rojas-Murcia, N., Nardeli, S. M., Goretti, D., & Schmid, M. (2021) · Journal of Experimental Botany · doi:10.1093/jxb/erab234 · Cited by 51

Plant Long Noncoding RNAs: New Players in the Field of Post-Transcriptional Regulations

Fonouni‐Farde, C., Ariel, F., & Crespi, M. D. (2021) · Non-Coding RNA · doi:10.3390/ncrna7010012 · Cited by 51

Alternative splicing of human NT5E in cirrhosis and hepatocellular carcinoma produces a negative regulator of ecto-5′-nucleotidase (CD73)

Snider, N. T., Altshuler, P. J., Wan, S., Welling, T. H., Cavalcoli, J. D., & Omary, M. B. (2014) · Molecular Biology of the Cell · doi:10.1091/mbc.e14-06-1167 · Cited by 49

Galectin-3 interacts with components of the nuclear ribonucleoprotein complex

Fritsch, K., Mernberger, M., Nist, A., Stiewe, T., Brehm, A., & Jacob, R. (2016) · BMC Cancer · doi:10.1186/s12885-016-2546-0 · Cited by 49

Multilayered heterogeneity as an intrinsic hallmark of neuroendocrine tumors

Pedraza‐Arévalo, S., Gahete, M. D., Alors‐Pérez, E., Luque, R. M., & Castano, J. P. (2018) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-018-9465-0 · Cited by 51

Significance of alternative splicing in cancer cells

Qi, F., Li, Y., Yang, X. F., Wu, Y., Lin, L., & Liu, X. (2019) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000542 · Cited by 50

Splicing factor BUD31 promotes ovarian cancer progression through sustaining the expression of anti-apoptotic BCL2L12

Wang, Z., Wang, S., Qin, J., Zhang, X., Lü, G., Liu, H., Guo, H., Wu, L., Shender, V. О., Shao, C., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-34042-w · Cited by 48

The Role of the U5 snRNP in Genetic Disorders and Cancer

Wood, K., Eadsforth, M. A., Newman, W. G., & O’Keefe, R. T. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.636620 · Cited by 48

A retrovirus packages nascent host noncoding RNAs from a novel surveillance pathway

Eckwahl, M. J., Sim, S., Smith, D., Telesnitsky, A., & Wolin, S. L. (2015) · Genes & Development · doi:10.1101/gad.258731.115 · Cited by 48

PRP4KA, a Putative Spliceosomal Protein Kinase, Is Important for Alternative Splicing and Development in Arabidopsis thaliana

Kanno, T., Venhuizen, P., Wen, T., Lin, W., Chiou, P., Kalyna, M., Matzke, A. J. M., & Matzke, M. A. (2018) · Genetics · doi:10.1534/genetics.118.301515 · Cited by 47

SMA-Causing Missense Mutations in Survival motor neuron (Smn) Display a Wide Range of Phenotypes When Modeled in Drosophila

Praveen, K., Wen, Y., Gray, K. M., Noto, J. J., Patlolla, A. R., Duyne, G. D. V., & Matera, A. G. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004489 · Cited by 47

Alternative splicing and cancer metastasis: prognostic and therapeutic applications

Marzese, D. M., Manughian-Peter, A. O., Orozco, J. I. J., & Hoon, D. S. �. (2018) · Clinical & Experimental Metastasis · doi:10.1007/s10585-018-9905-y · Cited by 47

RNA Splicing Analysis: From In Vitro Testing to Single-Cell Imaging

Ren, X., Zhang, K., Deng, R., & Li, J. (2019) · Chem · doi:10.1016/j.chempr.2019.05.027 · Cited by 49

Spliceosome Malfunction Causes Neurodevelopmental Disorders with Overlapping Features

Li, D., Wang, Q., Bayat, A., Battig, M. R., Zhou, Y., Bosch, D. G. M., van Haaften, G., Granger, L., Petersen, A. K., Pérez-Jurado, L. A., et al. (2024) · Journal of Clinical Investigation · doi:10.1172/jci171235 · Cited by 46

Integrated Metabolomic and Transcriptomic Analysis of the Flavonoid Accumulation in the Leaves of Cyclocarya paliurus at Different Altitudes

Du, Z., Lin, W., Yu, B., Zhu, J., & Li, J. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2021.794137 · Cited by 46

Understanding the mechanistic basis of non-coding RNA through molecular dynamics simulations

Palermo, G., Casalino, L., Magistrato, A., & McCammon, J. A. (2019) · Journal of Structural Biology · doi:10.1016/j.jsb.2019.03.004 · Cited by 47

Coordinated Regulation of Pre-mRNA Splicing by the SFPS-RRC1 Complex to Promote Photomorphogenesis

Xin, R., Kathare, P. K., & Huq, E. (2019) · The Plant Cell · doi:10.1105/tpc.18.00786 · Cited by 46

Human spliceosomal snRNA sequence variants generate variant spliceosomes

Mabin, J. W., Lewis, P. W., Brow, D. A., & Dvinge, H. (2021) · RNA · doi:10.1261/rna.078768.121 · Cited by 46

Connecting the “dots”: RNP granule network in health and disease

An, H., de Meritens, C. R., & Shelkovnikova, T. A. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2021.119058 · Cited by 48

Identification of transcriptome alterations in the prefrontal cortex, hippocampus, amygdala and hippocampus of suicide victims

Glăvan, D., Gheorman, V., Greșiță, A., Hermann, D. M., Udriștoiu, I., & Popa‐Wagner, A. (2021) · Scientific Reports · doi:10.1038/s41598-021-98210-6 · Cited by 48

METTL3 regulates breast cancer-associated alternative splicing switches

Achour, C., Bhattarai, D. P., Groza, P., Román, Á., & Aguiló, F. (2023) · Oncogene · doi:10.1038/s41388-023-02602-z · Cited by 45

An Inflammatory Checkpoint Generated by IL1RN Splicing Offers Therapeutic Opportunity for KRAS -Mutant Intrahepatic Cholangiocarcinoma

Zhang, M., Huang, Y., Pan, J., Sang, C., Lin, Y., Dong, L., Shen, X., Wu, Y. C., Song, G., Ji, S., et al. (2023) · Cancer Discovery · doi:10.1158/2159-8290.cd-23-0282 · Cited by 47

Splicing controls the ubiquitin response during DNA double-strand break repair

Pederiva, C., Böhm, S., Julner, A., & Farnebo, M. (2016) · Cell Death and Differentiation · doi:10.1038/cdd.2016.58 · Cited by 45

Transcriptional and Post-Transcriptional Mechanisms of the Development of Neocortical Lamination

Popovitchenko, T., & Rašin, M. (2017) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2017.00102 · Cited by 45

Functional Interaction between U1snRNP and Sam68 Insures Proper 3′ End Pre-mRNA Processing during Germ Cell Differentiation

Naro, C., Pellegrini, L., Jolly, A., Farini, D., Cesari, E., Bielli, P., de la Grange, P., & Sette, C. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.02.058 · Cited by 47

Alternative Splicing of ALS Genes: Misregulation and Potential Therapies

Perrone, B., Cognata, V. L., Sprovieri, T., Ungaro, C., Conforti, F. L., Andò, S., & Cavallaro, S. (2019) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-019-00717-0 · Cited by 45

Novel FMRP interaction networks linked to cellular stress

Taha, M. S., Haghighi, F., Stefanski, A., Nakhaei‐Rad, S., Jasemi, N. S. K., Kabbani, M. A. A., Görg, B., Fujii, M., Lang, P. A., Häussinger, D., et al. (2020) · FEBS Journal · doi:10.1111/febs.15443 · Cited by 51

SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2

Yu, A. Q., Wang, J., Jiang, S. T., Yuan, L. Q., Ma, H. Y., Hu, Y., Han, X. M., Tan, L. M., & Wang, Z. X. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.710479 · Cited by 45

Transcriptome-wide identification and study of cancer-specific splicing events across multiple tumors

Tsai, Y., Dominguez, D., Gomez, S. M., & Wang, Z. (2015) · Oncotarget · doi:10.18632/oncotarget.3145 · Cited by 48

Functional and genetic analysis of choroid plexus development in zebrafish

Henson, H. E., Parupalli, C., Ju, B., & Taylor, M. R. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00364 · Cited by 46

Splicing dysregulation in cancer: from mechanistic understanding to a new class of therapeutic targets

Wang, Y., Bao, Y., Zhang, S., & Wang, Z. (2020) · Science China Life Sciences · doi:10.1007/s11427-019-1605-0 · Cited by 44

Splicing mutations in inherited retinal diseases

Weisschuh, N., Buena‐Atienza, E., & Wissinger, B. (2020) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100874 · Cited by 46

At the Intersection of Major and Minor Spliceosomes: Crosstalk Mechanisms and Their Impact on Gene Expression

Akinyi, M. V., & Frilander, M. J. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.700744 · Cited by 44

Noncoding RNAs in Cardiac Hypertrophy and Heart Failure

Lu, P., Ding, F., Xiang, Y. K., Hao, L., & Zhao, M. (2022) · Cells · doi:10.3390/cells11050777 · Cited by 44

Characterizing excited conformational states of RNA by NMR spectroscopy

Zhao, B., & Zhang, Q. (2015) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2015.02.011 · Cited by 43

Human DBR1 modulates the recycling of snRNPs to affect alternative RNA splicing and contributes to the suppression of cancer development

Han, B., Park, H. K., Ching, T. H., Panneerselvam, J., Wang, H., Shen, Y., Zhang, J., Li, L., Che, R., Garmire, L. X., et al. (2017) · Oncogene · doi:10.1038/onc.2017.150 · Cited by 44

Dysregulation of cotranscriptional alternative splicing underlies CHARGE syndrome

Bélanger, C., Bérubé‐Simard, F., Leduc, E., Bernas, G., Campeau, P. M., Lalani, S. R., Martin, D. M., Bielas, S. L., Moccia, A., Srivastava, A., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1715378115 · Cited by 43

Development of an in vitro pre-mRNA splicing assay using plant nuclear extract

Albaqami, M., & Reddy, A. S. N. (2018) · Plant Methods · doi:10.1186/s13007-017-0271-6 · Cited by 43

Phosphoproteomic Analysis of the Highly-Metastatic Hepatocellular Carcinoma Cell Line, MHCC97-H

Tian, M., Cheng, H., Wang, Z., Su, N., Liu, Z., Sun, C., Zhen, B., Hong, X., Xue, Y., & Xu, P. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16024209 · Cited by 42

TDP-43 in nuclear condensates: where, how, and why

Lang, R., Hodgson, R. E., & Shelkovnikova, T. A. (2024) · Biochemical Society Transactions · doi:10.1042/bst20231447 · Cited by 42

A Quantitative Phosphoproteome Analysis of cGMP-Dependent Cellular Responses in Arabidopsis thaliana

Marondedze, C., Groen, A. J., Thomas, L. A., Lilley, K. S., & Gehring, C. (2015) · Molecular Plant · doi:10.1016/j.molp.2015.11.007 · Cited by 42

Aberrant RNA splicing and mutations in spliceosome complex in acute myeloid leukemia

Zhou, J., & Chng, W. J. (2017) · Stem Cell Investigation · doi:10.21037/sci.2017.01.06 · Cited by 43

TDP-43 regulates site-specific 2′-O-methylation of U1 and U2 snRNAs via controlling the Cajal body localization of a subset of C/D scaRNAs

Izumikawa, K., Nobe, Y., Ishikawa, H., Yamauchi, Y., Taoka, M., Sato, K., Nakayama, H., Simpson, R. J., Isobe, T., & Takahashi, N. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz086 · Cited by 42

Computing the Role of Alternative Splicing in Cancer

Liu, Z., & Rabadán, R. (2021) · Trends in cancer · doi:10.1016/j.trecan.2020.12.015 · Cited by 43

Biology of the mRNA Splicing Machinery and Its Dysregulation in Cancer Providing Therapeutic Opportunities

Blijlevens, M., Li, J., & van Beusechem, V. W. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22105110 · Cited by 43

What’s Wrong in a Jump? Prediction and Validation of Splice Site Variants

Riolo, G., Cantara, S., & Ricci, C. (2021) · Methods and Protocols · doi:10.3390/mps4030062 · Cited by 45

CRISPR/Cas9-mediated genome editing induces exon skipping by complete or stochastic altering splicing in the migratory locust

Chen, D., Tang, J., Li, B., Hou, L., Wang, X., & Kang, L. (2018) · BMC Biotechnology · doi:10.1186/s12896-018-0465-7 · Cited by 41

Spliceosome factors target timeless (tim) mRNA to control clock protein accumulation and circadian behavior in Drosophila

Shakhmantsir, I., Nayak, S., Grant, G. R., & Sehgal, A. (2018) · eLife · doi:10.7554/elife.39821 · Cited by 41

Epigenetic Alternations of MicroRNAs and DNA Methylation Contribute to Liver Metastasis of Colorectal Cancer

Liu, J., Li, H., Sun, L. L., Shen, S., Zhou, Q., Yuan, Y., & Xing, C. (2019) · Digestive Diseases and Sciences · doi:10.1007/s10620-018-5424-6 · Cited by 42

Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2

Kempf, J., Knelles, K., Hersbach, B. A., Petřík, D., Riedemann, T., Bednarova, V., Janjic, A., Simon‐Ebert, T., Enard, W., Smialowski, P., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109409 · Cited by 41

Developmental Analysis of Spliceosomal snRNA Isoform Expression

Lu, Z., & Matera, A. G. (2014) · G3 Genes Genomes Genetics · doi:10.1534/g3.114.015735 · Cited by 40

Host RNA Packaging by Retroviruses: A Newly Synthesized Story

Eckwahl, M. J., Telesnitsky, A., & Wolin, S. L. (2016) · mBio · doi:10.1128/mbio.02025-15 · Cited by 42

Analysis of the Roles of the Arabidopsis nMAT2 and PMH2 Proteins Provided with New Insights into the Regulation of Group II Intron Splicing in Land-Plant Mitochondria

Zmudjak, M., Shevtsov, S., Sultan, L. D., Keren, I., & Ostersetzer‐Biran, O. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18112428 · Cited by 40

Molecular basis of titin exon exclusion by RBM20 and the novel titin splice regulator PTB4

Dauksaite, V., & Gotthardt, M. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky165 · Cited by 40

Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2

Hamann, F., Schmitt, A., Favretto, F., Hofele, R. V., Neumann, P., Xiang, S., Urlaub, H., Zweckstetter, M., & Ficner, R. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1907960117 · Cited by 40

Splicing machinery is impaired in rheumatoid arthritis, associated with disease activity and modulated by anti-TNF therapy

Ibáñez‐Costa, A., Pérez‐Sánchez, C., Patiño-Trives, A. M., Luque-Tévar, M., Font, P., de la Rosa, I. A., Román-Rodríguez, C., Ábalos‐Aguilera, M. C., Conde, C., Gonzalez, A., et al. (2021) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2021-220308 · Cited by 40

Specific genomic cues regulate Cajal body assembly

Sawyer, I. A., Hager, G. L., & Dundr, M. (2016) · RNA Biology · doi:10.1080/15476286.2016.1243648 · Cited by 39

Alternative splicing diversifies the transcriptome and proteome of the rice blast fungus during host infection

Jeon, J., Kim, K., Choi, J., Cheong, K., Ko, J., Choi, G., Lee, H., Lee, G.-W., Park, S., Kim, S., et al. (2022) · RNA Biology · doi:10.1080/15476286.2022.2043040 · Cited by 38

Large-scale evaluation of the ability of RNA-binding proteins to activate exon inclusion

Schmok, J. C., Jain, M., Street, L. A., Tankka, A. T., Schafer, D. M., Her, H.-L., Elmsaouri, S., Gosztyla, M. L., Boyle, E. A., Jagannatha, P., et al. (2024) · Nature Biotechnology · doi:10.1038/s41587-023-02014-0 · Cited by 38

Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation

Prusty, A. B., Meduri, R., Prusty, B. K., Vanselow, J. T., Schlösser, A., & Fischer, U. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201611108 · Cited by 38

Characterization of cryptic splicing in germline PTEN intronic variants in Cowden syndrome

Chen, H. J., Romigh, T., Sesock, K., & Eng, C. (2017) · Human Mutation · doi:10.1002/humu.23288 · Cited by 38

Proper splicing contributes to visual function in the aging Drosophila eye

Stegeman, R., Hall, H., Escobedo, S. E., Chang, H. C., & Weake, V. M. (2018) · Aging Cell · doi:10.1111/acel.12817 · Cited by 38

Serine/Arginine-rich protein family of splicing regulators: New approaches to study splice isoform functions

Morton, M. J. L., Al‐Tamimi, N., Butt, H., Reddy, A. S. N., & Mahfouz, M. M. (2019) · Plant Science · doi:10.1016/j.plantsci.2019.02.017 · Cited by 39

Circular exonic RNAs: When RNA structure meets topology

Pervouchine, D. D. (2019) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2019.05.002 · Cited by 38

Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing

Li, J., Liu, F., Lv, Y., Sun, K., Zhao, Y., Reilly, J., Zhang, Y., Tu, J., Yu, S., Liu, X., et al. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab003 · Cited by 38

SMN - A chaperone for nuclear RNP social occasions?

Raimer, A. C., Gray, K. M., & Matera, A. G. (2016) · RNA Biology · doi:10.1080/15476286.2016.1236168 · Cited by 37

RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNA

Moldovan, J. B., Wang, Y., Shuman, S., Mills, R. E., & Moran, J. V. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1805404116 · Cited by 38

Influenza Virus RNA-Dependent RNA Polymerase and the Host Transcriptional Apparatus

Krischuns, T., Lukarska, M., Naffakh, N., & Cusack, S. (2021) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-072820-100645 · Cited by 40

RBM10 Loss Promotes EGFR -Driven Lung Cancer and Confers Sensitivity to Spliceosome Inhibition

Bao, Y., Zhang, S., Zhang, X., Pan, Y., Yan, Y., Wang, N., Ren, Y., Zuo, J., Zong, W., Wang, Z., et al. (2023) · Cancer Research · doi:10.1158/0008-5472.can-22-1549 · Cited by 37

Structural basis for the recognition of spliceosomal SmN/B/B’ proteins by the RBM5 OCRE domain in splicing regulation

Mourão, A., Bonnal, S., Soni, K., Warner, L., Bordonné, R., Valcárcel, J., & Sattler, M. (2016) · eLife · doi:10.7554/elife.14707 · Cited by 37

Disruption of the Caenorhabditis elegans Integrator complex triggers a non-conventional transcriptional mechanism beyond snRNA genes

Gómez‐Orte, E., Sáenz‐Narciso, B., Zheleva, A., Ezcurra, B., de Toro, M., López, R., Gastaca, I., Nilsen, H. L., Sacristán, M. P., Schnabel, R., et al. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1007981 · Cited by 37

Comprehensive Characterization of RNA Processing Factors in Gastric Cancer Identifies a Prognostic Signature for Predicting Clinical Outcomes and Therapeutic Responses

Lou, S., Meng, F., Yin, X., Zhang, Y., Han, B., & Xue, Y. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.719628 · Cited by 37

RNA Splicing of FLC Modulates the Transition to Flowering

Qi, H.-D., Lin, Y., Ren, Q.-P., Wang, Y., Xiong, F., & Wang, X. (2019) · Frontiers in Plant Science · doi:10.3389/fpls.2019.01625 · Cited by 36

Alternative splicing and its regulatory role in woody plants

Chen, M., Zhang, K., Zhang, M., Das, D., Fang, Y.-M., Dai, L., Zhang, J., & Zhu, F. (2020) · Tree Physiology · doi:10.1093/treephys/tpaa076 · Cited by 36

LncRNA CBR3-AS1 potentiates Wnt/β-catenin signaling to regulate lung adenocarcinoma cells proliferation, migration and invasion

Hou, M., Wu, N., & Yao, L. (2021) · Cancer Cell International · doi:10.1186/s12935-020-01685-y · Cited by 36

Presynaptic protein synthesis and brain plasticity: From physiology to neuropathology

Perrone‐Capano, C., Volpicelli, F., Penna, E., Chun, J. T., & Crispino, M. (2021) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2021.102051 · Cited by 37

Plant snRNP Biogenesis: A Perspective from the Nucleolus and Cajal Bodies

Ohtani, M. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2017.02184 · Cited by 36

Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study

Gahete, M. D., del Río-Moreno, M., Camargo, A., Alcala-Diaz, J. F., Alors‐Pérez, E., Delgado‐Lista, J., Reyes, Ó., Ventura, S., Pérez‐Martínez, P., Castano, J. P., et al. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.10.056 · Cited by 38

The splicing modulator sulfonamide indisulam reduces AR-V7 in prostate cancer cells

Melnyk, J. E., Steri, V., Nguyen, H. G., Hann, B. C., Feng, F. Y.-C., & Shokat, K. M. (2020) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2020.115712 · Cited by 35

Light regulates nuclear detainment of intron-retained transcripts through COP1-spliceosome to modulate photomorphogenesis

Zhou, H., Zeng, H., Yan, T., Chen, S., Fu, Y., Qin, G., Zhao, X., Heng, Y., Li, J., Lin, F., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-49571-9 · Cited by 35

Splicing Regulation: A Molecular Device to Enhance Cancer Cell Adaptation

Pagliarini, V., Naro, C., & Sette, C. (2015) · BioMed Research International · doi:10.1155/2015/543067 · Cited by 36

Extracellular genomic biomarkers of osteoarthritis

Budd, E., Nalesso, G., & Mobasheri, A. (2017) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2018.1415757 · Cited by 35

The multiple lives of DEAD-box RNA helicase DP103/DDX20/Gemin3

Curmi, F., & Cauchi, R. J. (2018) · Biochemical Society Transactions · doi:10.1042/bst20180016 · Cited by 35

Quantifying splice-site usage: a simple yet powerful approach to analyze splicing

Dent, C., Singh, S., Mukherjee, S., Mishra, S., Sarwade, R. D., Shamaya, N., Loo, K. P., Harrison, P. F., Sureshkumar, S., Powell, D., et al. (2021) · NAR Genomics and Bioinformatics · doi:10.1093/nargab/lqab041 · Cited by 34

A Challenging Pie to Splice: Drugging the Spliceosome

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