A day in the life of the spliceosome

Expansion of the eukaryotic proteome by alternative splicing

Nilsen, T. W., & Graveley, B. R. (2010) · Nature · doi:10.1038/nature08909 · Cited by 2,270

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

Fornerod, M. W. J., Ohno, M., Yoshida, M., & Mattaj, I. W. (1997) · Cell · doi:10.1016/s0092-8674(00)80371-2 · Cited by 2,086

Frequent pathway mutations of splicing machinery in myelodysplasia

Yoshida, K., Sanada, M., Shiraishi, Y., Nowak, D., Nagata, Y., Yamamoto, R., Sato, Y., Sato-Otsubo, A., Kon, A., Nagasaki, M., et al. (2011) · Nature · doi:10.1038/nature10496 · Cited by 2,029

Spliceosome Structure and Function

Will, C. L., & Luhrmann, R. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003707 · Cited by 1,829

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

Lorson, C. L., Hahnen, E., Androphy, E. J., & Wirth, B. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.11.6307 · Cited by 1,536

Spliced segments at the 5′ terminus of adenovirus 2 late mRNA

Berget, S. M., Moore, C. L., & Sharp, P. A. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.8.3171 · Cited by 1,483

Understanding alternative splicing: towards a cellular code

Matlin, A. J., Clark, F., & Smith, C. W. J. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1645 · Cited by 1,299

An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA

Chow, L. T., Gelinas, R. E., Broker, T. R., & Roberts, R. J. (1977) · Cell · doi:10.1016/0092-8674(77)90180-5 · Cited by 1,234

Are snRNPs involved in splicing?

Lerner, M. R., Boyle, J. A., Mount, S. M., Wolin, S. L., & STEITZ, J. A. (1980) · Nature · doi:10.1038/283220a0 · Cited by 1,192

Splicing regulation: From a parts list of regulatory elements to an integrated splicing code

Wang, Z., & Burge, C. B. (2008) · RNA · doi:10.1261/rna.876308 · Cited by 1,127

Combining genetic constraint with predictions of alternative splicing to prioritize deleterious splicing in rare disease studies

Cormier, M. J., Pedersen, B. S., Bayrak‐Toydemir, P., & Quinlan, A. R. (2022) · BMC Bioinformatics · doi:10.1186/s12859-022-05041-x · Cited by 11

Self-empowerment of life through RNA networks, cells and viruses

Villarreal, L. P., & Witzany, G. (2023) · F1000Research · doi:10.12688/f1000research.130300.1 · Cited by 12

Influence of transcriptional variants on metastasis

Poloni, J. D. F., & Bonatto, D. (2018) · RNA Biology · doi:10.1080/15476286.2018.1493328 · Cited by 11

Alternative splicing reprogramming in fungal pathogen Sclerotinia sclerotiorum at different infection stages on Brassica napus

Cheng, X., Zhao, C., Gao, L., Zeng, L., Xu, Y., Liu, F., Huang, J., Liú, L., Liu, S., & Zhang, X. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.1008665 · Cited by 10

RBM25 depletion suppresses the growth of colon cancer cells through regulating alternative splicing of MNK2

Zhi, L., Chen, C., Zhang, G., Huang, T. J., He, W., Zhang, J., Chen, D., Liu, J., Zhao, J., Qi, Y., et al. (2024) · Science China Life Sciences · doi:10.1007/s11427-023-2582-x · Cited by 10

Proteomic analysis of the SMN complex reveals conserved and etiologic connections to the proteostasis network

Matera, A. G., Steiner, R. E., Mills, C. A., McMichael, B. D., Herring, L. E., & Garcia, E. L. (2024) · Frontiers in RNA Research · doi:10.3389/frnar.2024.1448194 · Cited by 10

Aberrant pre-mRNA processing in cancer

Biswas, J., Boussi, L. S., Stein, E. M., & Abdel-Wahab, O. I. (2024) · The Journal of Experimental Medicine · doi:10.1084/jem.20230891 · Cited by 10

Perturbation of mRNA splicing in liver cancer: insights, opportunities and challenges

Jia, Q., Sun, X., Li, H., Guo, J., Niu, K., Chan, K. M., Bernards, R., Qin, W., & Jin, H. (2024) · Gut · doi:10.1136/gutjnl-2024-333127 · Cited by 10

The potential impact of RNA splicing abnormalities on immune regulation in endometrial cancer

Cao, M., Yan, J., Ding, Y. F., Zhang, Y., Sun, Y., Jiang, G., Zhang, Y., & Li, B. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07458-7 · Cited by 10

Rewriting endogenous human transcripts with dual CRISPR-guided 3′ trans-splicing

Chandrasekaran, S. S., Tau, C., Fu, B. X. H., Nemeth, M., Bartie, L. J., Pawluk, A., Konermann, S., & Hsu, P. D. (2026) · Cell Systems · doi:10.1016/j.cels.2025.101487 · Cited by 11

Turnover and replication analysis by isotope labeling (TRAIL) reveals the influence of tissue context on protein and organelle lifetimes

Hasper, J., Welle, K. A., Hryhorenko, J. R., Ghaemmaghami, S., & Buchwalter, A. L. (2023) · Molecular Systems Biology · doi:10.15252/msb.202211393 · Cited by 10

How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei cell

Nascimento, J. F., Souza, R. O. O., Alencar, M. B., Marsiccobetre, S., Murillo, A. M., Damasceno, F. S., Girard, R. M. B. M., Marchese, L., Luévano‐Martínez, L. A., Achjian, R. W., et al. (2023) · PLoS Pathogens · doi:10.1371/journal.ppat.1011522 · Cited by 10

Oncofetal SNRPE promotes HCC tumorigenesis by regulating the FGFR4 expression through alternative splicing

Wu, Q., Liao, R., Miao, C., Hasnat, M., Li, L., Sun, L., Wang, X., Yuan, Z., Jiang, Z., Zhang, L., et al. (2024) · British Journal of Cancer · doi:10.1038/s41416-024-02689-5 · Cited by 10

A novel G to A transition at initiation codon and exon-intron boundary of PAX9 identified in association with familial isolated oligodontia

Sarkar, T., Bansal, R., & Das, P. K. (2017) · Gene · doi:10.1016/j.gene.2017.08.020 · Cited by 10

Hiding in Plain Sight: Rediscovering the Importance of Noncoding RNA in Human Malignancy

Feeley, K. P., & Edmonds, M. D. (2018) · Cancer Research · doi:10.1158/0008-5472.can-17-2675 · Cited by 10

Characterization of viral RNA splicing using whole-transcriptome datasets from host species

Zhou, C., Liu, S., Song, W., Luo, S., Meng, G., Yang, C., Yang, H., Ma, J., Wang, L., Gao, S., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-21190-7 · Cited by 10

Competing RNA pairings in complex alternative splicing of a 3′ variable region

Pan, H., Shi, Y., Chen, S., Yang, Y., Yue, Y., Zhan, L., Dai, L., Dong, H., Hong, W., Shi, F., et al. (2018) · RNA · doi:10.1261/rna.066225.118 · Cited by 10

Influence of Age on Skeletal Muscle Hypertrophy and Atrophy Signaling: Established Paradigms and Unexpected Links

Lee, E. H., & Neppl, R. L. (2021) · Genes · doi:10.3390/genes12050688 · Cited by 11

A 10S galectin-3–U1 snRNP complex assembles into active spliceosomes

Haudek, K. C., Voss, P. G., Wang, J. L., & Patterson, R. J. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw303 · Cited by 10

Design, Synthesis, and Properties of Phosphoramidate 2′,5′-Linked Branched RNA: Toward the Rational Design of Inhibitors of the RNA Lariat Debranching Enzyme

Tago, N., Katolik, A., Clark, N. E., Montemayor, E., Seio, K., Sekine, M., Hart, P. J., & Damha, M. J. (2015) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.5b01719 · Cited by 10

Nonmammalian Animal Models of Spinal Muscular Atrophy

O’Hern, P., Garcia, E. L., Hao, L. T., Hart, A. C., Matera, A. G., & Beattie, C. E. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803685-3.00014-8 · Cited by 10

Splicing machinery genomics events in acute myeloid leukaemia (AML): in search for therapeutic targets, diagnostic and prognostic biomarkers.

Dlamini, Z., Shoba, B., & Hull, R. (2020) · PubMed Central · Cited by 10

Unraveling the stepwise maturation of the yeast telomerase including a Cse1 and Mtr10 mediated quality control checkpoint

Hirsch, A. G., Becker, D., Lamping, J.-P., & Krebber, H. (2021) · Scientific Reports · doi:10.1038/s41598-021-01599-3 · Cited by 10

Cassava MeRS40 is required for the regulation of plant salt tolerance

Xiao-wen, M. A., Ma, Q., Ma, M., Chen, Y., Gu, J., Yang, L., Hu, Q., Luo, Q., Wen, M., Zhang, P., et al. (2023) · Journal of Integrative Agriculture · doi:10.1016/j.jia.2023.04.003 · Cited by 9

Alternative Splicing, An Overlooked Defense Frontier of Plants with Respect to Bacterial Infection

Xie, J., Zhou, X., Jia, Z., Su, C., Zhang, Y., Fernie, A. R., Zhang, J., Du, Z., & Chen, M. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c04163 · Cited by 10

It is not just about transcription: involvement of brain RNA splicing in substance use disorders

de Carvalho, L. M., & Lasek, A. W. (2024) · Journal of Neural Transmission · doi:10.1007/s00702-024-02740-y · Cited by 9

The regulatory landscape of interacting RNA and protein pools in cellular homeostasis and cancer

Gallardo-Dodd, C. J., & Kutter, C. (2024) · Human Genomics · doi:10.1186/s40246-024-00678-6 · Cited by 9

RNA Through Time: From the Origin of Life to Therapeutic Frontiers in Transcriptomics and Epitranscriptional Medicine

Campos, C. M., Lanz‐Mendoza, H., Cime‐Castillo, J., Peralta-Zaragoza, Ó., & Madrid‐Marina, V. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26114964 · Cited by 10

The splice of life: how alternative splicing shapes regulatory and phenotypic evolution

Hunter, C. E., & Xing, Y. (2026) · The EMBO Journal · doi:10.1038/s44318-025-00666-z · Cited by 9

L’épissage des ARN pré-messagers : quand le splicéosome perd pied

Dujardin, G., Daguenet, É., Bernard, D. G., Flodrops, M., Durand, S., Chauveau, A., Khoury, F. E., Jossic-Corcos, C. L., & Corcos, L. (2016) · médecine/sciences · doi:10.1051/medsci/20163212014 · Cited by 9

Variants in LSM7 impair LSM complexes assembly, neurodevelopment in zebrafish and may be associated with an ultra-rare neurological disease

Derksen, A., Shih, H., Forget, D., Darbelli, L., Tran, L. T., Poitras, C., Guerrero, K., Tharun, S., Alkuraya, F. S., Kurdi, W., et al. (2021) · Human Genetics and Genomics Advances · doi:10.1016/j.xhgg.2021.100034 · Cited by 9

Probing Isoform Switching Events in Various Cancer Types: Lessons From Pan-Cancer Studies

Karakulak, T., Moch, H., von Mering, C., & Kahraman, A. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.726902 · Cited by 10

PacBio Isoform Sequencing and Illumina RNA Sequencing Provide Novel Insights on Responses to Acute Heat Stress in Apostichopus japonicus Coelomocytes

Wang, Y., Yin, Y., Cong, X., Storey, K. B., & Chen, M. (2022) · Frontiers in Marine Science · doi:10.3389/fmars.2021.815109 · Cited by 9

Border cell polarity and collective migration require the spliceosome component Cactin

Miao, G., Guo, L., & Montell, D. J. (2022) · The Journal of Cell Biology · doi:10.1083/jcb.202202146 · Cited by 9

Viruses and Cajal Bodies: A Critical Cellular Target in Virus Infection?

Lettin, L., Erbay, B., & Blair, G. E. (2023) · Viruses · doi:10.3390/v15122311 · Cited by 9

Dysregulation of innate immune signaling in animal models of spinal muscular atrophy

Garcia, E. L., Steiner, R. E., Raimer, A. C., Herring, L. E., Matera, A. G., & Spring, A. M. (2024) · BMC Biology · doi:10.1186/s12915-024-01888-z · Cited by 9

RNA structure in alternative splicing regulation: from mechanism to therapy

Bao, N., Wang, Z., Fu, J., Dong, H., & Jin, Y. (2024) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2024119 · Cited by 9

A study of splicing mutations in disorders of sex development

de Calais, F. L., Smith, L., Raponi, M., Maciel‐Guerra, A. T., Guerra‐Júnior, G., de Mello, M. P., & Baralle, D. (2017) · Scientific Reports · doi:10.1038/s41598-017-16296-3 · Cited by 10

Scalable Synthesis of 17S-FD-895 Expands the Structural Understanding of Splice Modulatory Activity

Chan, W. C., Clair, J. J. L., León, B., Trieger, K. A., Slagt, M. Q., Verhaar, M. T., Bachera, D. U., Rispens, M. T., Hofman, R. M., de Boer, V. L., et al. (2020) · Cell Reports Physical Science · doi:10.1016/j.xcrp.2020.100277 · Cited by 9

Induction of cryptic pre-mRNA splice-switching by antisense oligonucleotides

Ham, K. A., Keegan, N., McIntosh, C. S., Aung-Htut, M. T., Zaw, K., Greer, K., Fletcher, S., & Wilton, S. D. (2021) · Scientific Reports · doi:10.1038/s41598-021-94639-x · Cited by 9

Combining Chemical Synthesis and Enzymatic Methylation to Access Short RNAs with Various 5′ Caps

Muthmann, N., Guez, T., Vasseur, J., Jaffrey, S. R., Debart, F., & Rentmeister, A. (2019) · ChemBioChem · doi:10.1002/cbic.201900037 · Cited by 9

The Diverse Requirements of ARS2 in nuclear cap-binding complex-dependent RNA Processing

(2016) · RNA & DISEASE · doi:10.14800/rd.1376 · Cited by 9

Recent advances in methods for live-cell RNA imaging

Pham, T. G., & Wu, J. (2024) · Nanoscale · doi:10.1039/d4nr00129j · Cited by 8

SNRPB2 promotes triple‐negative breast cancer progression by controlling alternative splicing of MDM4 pre‐ mRNA

Yu, S., Si, Y., Yu, J., Jiang, C., Cheng, F., Xu, M., Fan, Z., Liu, F., Liu, C., Wang, Y., et al. (2024) · Cancer Science · doi:10.1111/cas.16356 · Cited by 8

Retinitis pigmentosa-linked mutations impair the snRNA unwinding activity of SNRNP200 and reduce pre-mRNA binding of PRPF8

Zimmann, F., McNicoll, F., Thakur, P. K., Blažíková, M., Kubovčiak, J., Cañás, M. C. H., Nováková, Z., Bařinka, C., Kolář, M., Staněk, D., et al. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05621-z · Cited by 8

The Exserohilum turcicum effector EtEC81 reprograms alternative splicing in maize and activates immunity

Yu, H., Shi, X., Ning, N., Wu, H., Mei, J., Gu, X., Ruan, H., Zhang, M., Li, Z., Ma, S., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115501 · Cited by 8

Artificial intelligence-driven plant bio-genomics research: a new era

Yang, L., Wang, H., Zou, M., Chai, H., & Xia, Z. (2025) · Tropical Plants · doi:10.48130/tp-0025-0008 · Cited by 11

Spliceosome complex and neurodevelopmental disorders

Deutsch, H. M., Song, Y., & Li, D. (2025) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2025.102358 · Cited by 8

Variety of Non-Coding RNAs in Eukaryotic Genomes

Nazipova, N. N. (2021) · Mathematical Biology and Bioinformatics · doi:10.17537/2021.16.256 · Cited by 8

Unravelling the Initial Triggers of Botrytis cinerea Infection: First Description of Its Surfactome

Escobar-Niño, A., Carrasco-Reinado, R., Bermejo, I. M. M., Cantoral, J. M., & Fernández‐Acero, F. J. (2021) · Journal of Fungi · doi:10.3390/jof7121021 · Cited by 8

CHERP Regulates the Alternative Splicing of pre-mRNAs in the Nucleus

Yamanaka, Y., Ishizuka, T., Fujita, K., Fujiwara, N., Kurata, M., & Masuda, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052555 · Cited by 8

Conserved role for PCBP1 in altered RNA splicing in the hippocampus after chronic alcohol exposure

de Carvalho, L. M., Chen, H., Maienschein‐Cline, M., Glover, E. J., Pandey, S. C., & Lasek, A. W. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02184-y · Cited by 8

The interferon-regulated host factor hnRNPA0 modulates HIV-1 production by interference with LTR activity, mRNA trafficking, and programmed ribosomal frameshifting

Roesmann, F., Sertznig, H., Klaassen, K., Wilhelm, A., Heininger, D., Heß, S., Elsner, C., Marschalek, R., Santiago, M. L., Eßer, S., et al. (2024) · Journal of Virology · doi:10.1128/jvi.00534-24 · Cited by 8

Signature microRNAs of nuclear Sm complex associated with breast cancer tumorigenesis

Zhang, X., Bo, S., & Cui, Y. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26697 · Cited by 8

Splicing regulation in hematopoiesis

Chen, S., & Abdel-Wahab, O. I. (2021) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000661 · Cited by 9

U6 snRNA intron insertion occurred multiple times during fungi evolution

Canzler, S., Stadler, P. F., & Jana Hertel, A. (2016) · RNA Biology · doi:10.1080/15476286.2015.1132139 · Cited by 8

The conserved AU dinucleotide at the 5′ end of nascent U1 snRNA is optimized for the interaction with nuclear cap-binding-complex

Yeh, C.-S., Chang, S., Chen, J.-H., Wang, H.-K., Chou, Y.-C., Wang, C.-H., Huang, S.-H., Larson, A., Pleiss, J. A., Chang, W., et al. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx608 · Cited by 8

ABCA4 c.859-25A>G, a Frequent Palestinian Founder Mutation Affecting the Intron 7 Branchpoint, Is Associated With Early-Onset Stargardt Disease

Corradi, Z., Salameh, M., Khan, M., Héon, E., Mishra, K., Hitti‐Malin, R. J., AlSwaiti, Y., Aslanian, A., Banin, E., Brooks, B. P., et al. (2022) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.63.4.20 · Cited by 8

Inherited Retinal Disease Therapies Targeting Precursor Messenger Ribonucleic Acid

Huang, D., Fletcher, S., Wilton, S. D., Palmer, N. T., McLenachan, S., Mackey, D. A., & Chen, F. K. (2017) · Vision · doi:10.3390/vision1030022 · Cited by 8

The landscape of alternative splicing reveals novel events associated with tumorigenesis and the immune microenvironment in gastric cancer

Lou, S., Zhang, J., Zhai, Z., Yin, X., Wang, Y., Fang, T., & Xue, Y. (2021) · Aging · doi:10.18632/aging.202393 · Cited by 8

Recent Advances in Research on Molecular Mechanisms of Fungal Signaling

Jacob, S., Bühring, S., & Bersching, K. (2022) · Encyclopedia · doi:10.3390/encyclopedia2020055 · Cited by 8

The U1 small nuclear RNA enhances drought tolerance in Arabidopsis

Wang, F., Li, Y., Yuan, J., Li, C., Lin, Y., Gu, J., & Wang, Z. (2024) · PLANT PHYSIOLOGY · doi:10.1093/plphys/kiae389 · Cited by 7

RNA 3′end tailing safeguards cells against products of pervasive transcription termination

Wu, G., Rouvière, J. O., Schmid, M., & Jensen, T. H. (2024) · Nature Communications · doi:10.1038/s41467-024-54834-6 · Cited by 7

Pathogenic Variants in RNU2‐2 , a Non‐coding Spliceosomal RNA , Cause a Distinctive Developmental and Epileptic Encephalopathy

Chiu, A. T. G., Bennett, M. F., Thiyagarajah, H., Schneider, A., Macdonald, S. M. W., Witkowski, T., Fuerte, E. P. A., Allan, T. J., Lieffering, N., Robinson, B., et al. (2025) · Annals of Neurology · doi:10.1002/ana.78071 · Cited by 7

Small nuclear RNA genes in Mendelian disorders

Antonarakis, S. E. (2025) · Nature Genetics · doi:10.1038/s41588-025-02440-7 · Cited by 7

The mutation in splicing factor genes correlates with unfavorable prognosis, genomic instability, anti-tumor immunosuppression and increased immunotherapy response in pan-cancer

Luo, J., Chen, C., Liu, Z., & Wang, X. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1045130 · Cited by 7

Mechanism of assembly of snRNP cores assisted by ICln and the SMN complex in fission yeast

Hu, Y., Hou, Y., Zhou, S., Wang, Y., Shen, C., Li, M., Su, D., & Zhang, R. (2023) · iScience · doi:10.1016/j.isci.2023.107604 · Cited by 7

PRMT5 regulates the polysaccharide content by controlling the splicing of thaumatin-like protein in Ganoderma lucidum

Liu, R., Yang, Z., Yang, T., Wang, Z., Chen, X., Zhu, J. K., Ren, A., Shi, L., Yu, H., & Zhao, M. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.02906-23 · Cited by 7

snRNAs from Radical Prostatectomy Specimens Have the Potential to Serve as Prognostic Factors for Clinical Recurrence after Biochemical Recurrence in Patients with High-Risk Prostate Cancer

Mikami, H., Noguchi, S., Akatsuka, J., Hasegawa, H., Obayashi, K., Takeda, H., Endo, Y., Toyama, Y., Takei, H., Kimura, G., et al. (2024) · Cancers · doi:10.3390/cancers16091757 · Cited by 7

The Arabidopsis splicing factor PORCUPINE / S m E 1 orchestrates temperature‐dependent root development via auxin homeostasis maintenance

Arbi, N. E., Nardeli, S. M., Šimura, J., Ljung, K., & Schmid, M. (2024) · New Phytologist · doi:10.1111/nph.20153 · Cited by 7

Synthesis of an RBM39 Degrader That Downregulates CEP192 and Induces Disorganized Spindle Structures

Lyu, X., Wang, X., Lin, D., Lu, Y., Wang, C., Yan, Z., Wang, Z., Cheng, Y., Cheng, J., Ren, X., et al. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c00534 · Cited by 7

A unique mechanism of snRNP core assembly

Wang, Y., Chen, X., Kong, X., Chen, Y., Xiang, Z., Xiang, Y., Hu, Y., Hou, Y., Zhou, S., Shen, C., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-58461-7 · Cited by 7

Enhancing RNA base editing on mammalian transcripts with small nuclear RNAs

Smargon, A. A., Pant, D., Gomberg, T. A., Fagre, C. R., Glynne, S., Nguyen, J., Naritomi, J. T., Gilbert, W. V., & Yeo, G. W.-M. (2025) · Nature Chemical Biology · doi:10.1038/s41589-025-02026-8 · Cited by 7

Repression of ABA-responsive alternative splicing by an Arabidopsis SR protein relieves ABA inhibition of early plant growth

Laloum, T., Martín, G., Lewinski, M., Yanez, R. J. R., Köster, T., Paixão, T., Staiger, D., & Duque, P. (2026) · The Plant Cell · doi:10.1093/plcell/koag127 · Cited by 7

Non-Canonical Functions of Splicing Factors in RNA Metabolism

Xiao, H., Lin, Y., Gao, X., & Wang, X. (2020) · Critical Reviews in Plant Sciences · doi:10.1080/07352689.2020.1857602 · Cited by 7

Molecular characterization of colorectal cancer

Liang, Q., Du, X., Mao, L., & Wang, G. (2021) · Saudi Journal of Gastroenterology · doi:10.4103/sjg.sjg_530_20 · Cited by 7

Genomics and splicing events of type II endometrial cancers in the black population: racial disparity, socioeconomic and geographical differences.

Francies, F. Z., Marima, R. M., Hull, R., Molefi, T., & Dlamini, Z. (2020) · PubMed Central · Cited by 7

Characterization of the aberrant splicing of MAP3K7 induced by cancer-associated SF3B1 mutation

Li, Z., Zhao, B., Shi, Y., Liang, Y., Qian, R., & Wan, Y. (2021) · The Journal of Biochemistry · doi:10.1093/jb/mvab023 · Cited by 8

Intron Retained Bioluminescence Reporter for Real-Time Imaging of Pre-mRNA Splicing in Living Subjects

Zheng, H., Chen, S., Wang, X., Xie, J., Tian, J., & Wang, F. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.9b02935 · Cited by 7

Translation of gastric disease progression at gene level expression

Morales-Guerrero, S. E., Rivas-Ortiz, C. I., de León-Rosales, S. P., Gamboa‐Domínguez, A., Rangel‐Escareño, C., Uscanga-Domínguez, L. F., Aguilar‐Gutiérrez, G. R., Kershenobich, D., Castillo-Rojas, G., & López‐Vidal, Y. (2019) · Journal of Cancer · doi:10.7150/jca.29038 · Cited by 7

Erratum: A day in the life of the spliceosome

Matera, A. G., & Wang, Z. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3778 · Cited by 7

Defining the roles of the Integrator, NEXT, and nuclear exosome complexes in Drosophila oogenesis

Lee, Y., Biasini, A., Tipping, C., Hong, S. H., & Zamore, P. D. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116329 · Cited by 6

Cytosolic CRISPR RNAs for efficient application of RNA-targeting CRISPR-Cas systems

Cheng, E. C. K., Lam, J., & Kwon, S. C. (2025) · EMBO Reports · doi:10.1038/s44319-025-00399-4 · Cited by 6

Blood-based epigenetic biomarkers in rheumatoid arthritis: current knowledge and future perspectives

Mołoń, A., Kubis, H., Żurawska, J., & Cieśla, M. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1753808 · Cited by 7

RNA processing and protein expression of HLA ‐B*07: 44N

Balas, A., García‐Sánchez, F., & Vicario, J. L. (2017) · HLA · doi:10.1111/tan.12983 · Cited by 6

Splicing machinery is profoundly altered in systemic lupus erythematosus and antiphospholipid syndrome and directly linked to key clinical features

López-Pedrera, C., Patiño-Trives, A. M., Cerdó, T., Castro, R. O., Sanchez-Pareja, I., Ibáñez‐Costa, A., Muñoz-Barrera, L., Ábalos‐Aguilera, M. C., Ruiz, D., Azpilcueta, P. S., et al. (2023) · Journal of Autoimmunity · doi:10.1016/j.jaut.2022.102990 · Cited by 6

Targeting dysregulated splicing factors in cancer: lessons learned from RBM10 deficiency

Wang, Y., & Wang, Z. (2023) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjad063 · Cited by 6

Cooperation and Competition of RNA Secondary Structure and RNA–Protein Interactions in the Regulation of Alternative Splicing

Vorobeva, M. A., Skvortsov, D. A., & Pervouchine, D. D. (2024) · Acta Naturae · doi:10.32607/actanaturae.26826 · Cited by 6

Alternative Splicing Landscape of Head and Neck Squamous Cell Carcinoma

Wu, K., Sun, Q., Liu, D., Lu, J., Wen, D., Xi-Yan, Z. A. N. G., & Gao, L. (2024) · Technology in Cancer Research & Treatment · doi:10.1177/15330338241272051 · Cited by 6

SE ‐ lncRNAs in Cancer: Classification, Subcellular Localisation, Function and Corresponding TFs

Bao, Y., Teng, S., Zhai, H., Zhang, Y., Xu, Y., Li, C., Chen, Z., Ren, F., & Wang, Y. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70296 · Cited by 6

The role of Arabidopsis Splicing Factor 30 in floral transition and the implications of its alternative splicing

Zhang, D., Li, M., Aslam, M. M., Huang, M., Chen, M., Liu, Y., & Zhang, J. (2025) · PLANT PHYSIOLOGY · doi:10.1093/plphys/kiaf335 · Cited by 6

Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs

Lian, X., Zhao, M., Ji, X., He, Y., & Zhang, L. (2020) · Aging Clinical and Experimental Research · doi:10.1007/s40520-020-01509-z · Cited by 6

Alternative RNA splicing in cancer: what about adult T-cell leukemia?

Tram, J., Mesnard, J.-M., & Péloponèse, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.959382 · Cited by 6

Design, Synthesis, and Characterization of a Novel 2′–5′-Linked Amikacin-Binding Aptamer: An Experimental and MD Simulation Study

Mathivanan, J., Bai, Z., Chen, A. A., & Sheng, J. (2022) · ACS Chemical Biology · doi:10.1021/acschembio.2c00653 · Cited by 6

Regulation of alternative splicing by retrograde and light signals converges to control chloroplast proteins

Martín, G. (2023) · Frontiers in Plant Science · doi:10.3389/fpls.2023.1097127 · Cited by 6

RNA epitranscriptomics dysregulation: A major determinant for significantly increased risk of ASD pathogenesis

Béopoulos, A., Géa, M., Fasano, A., & Iris, F. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1101422 · Cited by 6

Mutation of Arabidopsis SME1 and Sm core assembly improves oxidative stress resilience

Willems, P., Ruyskensvelde, V. V., Maruta, T., Pottie, R., Fernández-Fernández, Á. D., Pauwels, J., Hannah, M. A., Gevaert, K., Breusegem, F. V., & Kelen, K. V. D. (2023) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2023.02.025 · Cited by 6

Transcriptomic Changes in Response to Form of Selenium on the Interferon-Tau Signaling Mechanism in the Caruncular Tissue of Beef Heifers at Maternal Recognition of Pregnancy

Carr, S. N., Crites, B., Shinde, H., & Bridges, P. J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417327 · Cited by 6

Toward RNA Repair of Diamond Blackfan Anemia Hematopoietic Stem Cells

d’Allard, D., & Liu, J. M. (2016) · Human Gene Therapy · doi:10.1089/hum.2016.081 · Cited by 6

Examining the intersection between splicing, nuclear export and small RNA pathways

Nabih, A., Sobotka, J. A., Wu, M. Z., Wedeles, C. J., & Claycomb, J. M. (2017) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2017.05.027 · Cited by 6

Identification and characterization of small molecule inhibitors of pre-mRNA splicing that block spliceosome assembly at novel stages

Sidarovich, A. (2016) · doi:10.53846/goediss-5520

Transcriptome-wide splicing network reveals specialized regulatory functions of the core spliceosome

Rogalska, M. E., Mancini, E., Bonnal, S., Gohr, A., Dunyak, B. M., Arecco, N., Smith, P. G., Vaillancourt, F. H., & Valcárcel, J. (2024) · Science · doi:10.1126/science.adn8105 · Cited by 106

RNA Splicing and Genes

Sharp, P. A. (1988) · JAMA · doi:10.1001/jama.1988.03410200091032 · Cited by 21

Spliceosomes

Chen, W., & Moore, M. J. (2015) · Current Biology · doi:10.1016/j.cub.2014.11.059 · Cited by 75

The nuts and bolts of the endogenous spliceosome

Sperling, R. (2016) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1377 · Cited by 40