The selection and function of cell type-specific enhancers
Heinz, Sven, Romanoski, Casey E., Benner, Christopher, Glass, Christopher K.·2015·Nature Reviews Molecular Cell Biology
DOI 10.1038/nrm3949
Cited by (1,001)
Items 101–200 of 1,001
- A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast CancerChi Zhu, Li Li, Zhao Zhang, Mingjun Bi, Hu Wang, Wenyue Su, Karen Hernandez, Pingping Liu, Junqiang Chen, Mingqiu Chen et al. · 2019 · Molecular Cell
- The transcription factor ERG regulates super-enhancers associated with an endothelial-specific gene expression programKalna, Viktoria, Yang, Youwen, Peghaire, Claire R., Frudd, Karen, Hannah, Rebecca, Shah, Aarti V., Osuna Almagro, Lourdes, Boyle, Joseph J., Göttgens, Berthold, Ferrer, Jorge et al. · 2019 · Circulation Research
- Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State TransitionNovo, Clara Lopes, Javierre, Biola-Maria, Cairns, Jonathan, Segonds-Pichon, Anne, Wingett, Steven W., Freire-Pritchett, Paula, Furlan-Magaril, Mayra, Schoenfelder, Stefan, Fraser, Peter, Rugg-Gunn, Peter J. · 2018 · Cell Reports
- Genome-wide identification of the genetic basis of amyotrophic lateral sclerosisSai Zhang, Johnathan Cooper‐Knock, Annika K K Weimer, Minyi Shi, Tobias Moll, Jack N.G. Marshall, Calum Harvey, Helia Ghahremani Nezhad, John Franklin, Cleide Dos Santos Souza et al. · 2022 · Neuron
- Programmable eukaryotic protein synthesis with RNA sensors by harnessing ADARKaiyi Jiang, Jeremy G. Koob, Xi Dawn Chen, Rohan N. Krajeski, Yifan Zhang, Verena Volf, Wenyuan Zhou, Samantha R. Sgrizzi, Lukas Villiger, Jonathan S. Gootenberg et al. · 2022 · Nature Biotechnology
- Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed bindingIan C. McDowell, Alejandro Barrera, Anthony M. D’Ippolito, Christopher M. Vockley, Linda K. Hong, Sarah M. Leichter, Luke C. Bartelt, William H. Majoros, Lingyun Song, Alexias Safi et al. · 2018 · Genome Research
- Transcriptional Regulation by (Super)Enhancers: From Discovery to MechanismsGrosveld, Frank, van Staalduinen, Jente, Stadhouders, Ralph · 2021 · Annual Review of Genomics and Human Genetics
- IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s DiseaseLau, Shun-Fat, Chen, Congping, Fu, Wing-Yu, Qu, Jianan Y., Cheung, Tom H., Fu, Amy K.Y., Ip, Nancy Y. · 2020 · Cell Reports
- Glycogen Synthase Kinase-3α Promotes Fatty Acid Uptake and Lipotoxic CardiomyopathyMichinari Nakamura, Tong Liu, Seema Husain, Peiyong Zhai, Junco S. Warren, Chiao‐Po Hsu, Takahisa Matsuda, Christopher J. Phiel, James Eric Cox, Bin Tian et al. · 2019 · Cell Metabolism
- Roles and regulation of microglia activity in multiple sclerosis: insights from animal modelsFélix Distéfano‐Gagné, Sara Bitarafan, Steve Lacroix, David Gosselin · 2023 · Nature reviews. Neuroscience
- IRF1 Maintains Optimal Constitutive Expression of Antiviral Genes and Regulates the Early Antiviral ResponseDebasis Panda, Erisa Gjinaj, Mahesh Bachu, Erica Squire, Hilary Novatt, Keiko Ozato, Ronald L. Rabin · 2019 · Frontiers in Immunology
- Super-enhancers and the super-enhancer reader BRD4: tumorigenic factors and therapeutic targetsHaihong Qian, Min Zhu, Xinyu Tan, Yixing Zhang, Xiangning Liu, Li Yang · 2023 · Cell Death Discovery
- Molecular and genetic insights into human ovarian aging from single-nuclei multi-omics analysesChen Jin, Xizhe Wang, Jiping Yang, Seung-Soo Kim, Adam D. Hudgins, Amir Gamliel, Mingzhuo Pei, Daniela Contreras, Melody Devos, Qinghua Guo et al. · 2024 · Nature Aging
- Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal CarcinomaYuan Ying Jiang, Yan-Yi Jiang, Anand Mayakonda, Moli Huang, Ling‐Wen Ding, Lin Han, Fenggang Yu, Yanan Lu, Thomas Kwok Seng Loh, Marilynn Chow et al. · 2017 · Cancer Research
- Inhibitors of bromodomain and extra‐terminal proteins for treating multiple human diseasesEwelina Kulikowski, Brooke D. Rakai, Norman C.W. Wong · 2020 · Medicinal Research Reviews
- Regulation and functional roles of chemokines in liver diseasesSheng Cao, Mengfei Liu, Tejasav S. Sehrawat, Vijay H. Shah · 2021 · Nature Reviews Gastroenterology & Hepatology
- Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific EnhancersHisayuki Hashimoto, Zhaoning Wang, Glynnis A. Garry, Venkat S. Malladi, Giovanni A. Botten, Wenduo Ye, Huanyu Zhou, Marco Osterwalder, Diane E. Dickel, Axel Visel et al. · 2019 · Cell stem cell
- Enabling functional genomics with genome engineeringIsaac B. Hilton, Charles A. Gersbach · 2015 · Genome Research
- Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivoSubramanian, Sethuraman, Busch, Clara Jana-Lui, Molawi, Kaaweh, Geirsdottir, Laufey, Maurizio, Julien, Vargas Aguilar, Stephanie, Belahbib, Hassiba, Gimenez, Gregory, Yuda, Ridzky Anis Advent, Burkon, Michaela et al. · 2022 · Nature Immunology
- The Mediator kinase module: an interface between cell signaling and transcriptionOlivia Luyties, Dylan J. Taatjes · 2022 · Trends in Biochemical Sciences
- Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signalingHoma Rahnamoun, Hanbin Lu, Sascha H. C. Duttke, Christopher W. Benner, Christopher K. Glass, Shannon M. Lauberth · 2017 · Nature Communications
- MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiationYu Fen Zhao, Jiajian Zhou, Liangqiang He, Yuying Li, Jie Yuan, Kun Sun, Xiaona Chen, Xichen Bao, Miguel Angel Esteban, Hao Sun et al. · 2019 · Nature Communications
- Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcriptionYumiko Oishi, Shinichiro Hayashi, Takayuki Isagawa, Motohiko Oshima, Atsushi Iwama, Shigeki Shimba, Hitoshi Okamura, Ichiro Manabe · 2017 · Scientific Reports
- Intragenic Enhancers Attenuate Host Gene ExpressionCinghu, Senthilkumar, Yang, Pengyi, Kosak, Justin P., Conway, Amanda E., Kumar, Dhirendra, Oldfield, Andrew J., Adelman, Karen, Jothi, Raja · 2017 · Molecular Cell
- The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cellsMichael Poppe, Sascha Wittig, Liane Jurida, Marek Bartkuhn, Jochen Wilhelm, Helmut Müller, Knut Beuerlein, Nadja Karl, Sabin Bhuju, John Ziebuhr et al. · 2017 · PLoS Pathogens
- A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interfaceLeonardo M. R. Ferreira, Torsten B Meissner, Tarjei Sigurd Mikkelsen, William Mallard, Charles W. O’Donnell, Tamara Tilburgs, Hannah Ananda Bougleux Gomes, Raymond Camahort, Richard I. Sherwood, David Kenneth Gifford et al. · 2016 · Proceedings of the National Academy of Sciences
- Targeting Super-Enhancers for Disease Treatment and Diagnosis.Ha Youn Shin · 2018 · Europe PMC (PubMed Central)
- Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene ExpressionIan K. Quigley, Chris R. Kintner · 2017 · PLoS Genetics
- Microglia: Phagocytosing to Clear, Sculpt, and EliminateSoyon Youngae Hong, Beth Stevens · 2016 · Developmental Cell
- An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cellsDominik Aschenbrenner, Mathilde Foglierini, David Jarrossay, Dan Hu, Howard L. Weiner, Vijay Kumar Kuchroo, Antonio Lanzavecchia, Samuele Notarbartolo, Federica Sallusto · 2018 · Nature Immunology
- Transcriptional Regulation of InflammasomesMaxence Cornut, Emilie Bourdonnay, Thomas Henry · 2020 · International Journal of Molecular Sciences
- Chromatin Regulation of Neuronal Maturation and PlasticityDavid A. Gallegos, Urann Chan, Liangfu Chen, Anne E. West · 2018 · Trends in Neurosciences
- Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cellsNicholas T Hogan, Michael Bernard Whalen, Lindsey K. Stolze, Nizar K Hadeli, Michael T. Y. Lam, James R. Springstead, Christopher K. Glass, Casey E. Romanoski · 2017 · eLife
- Progress and challenges in bioinformatics approaches for enhancer identificationDimitrios Kleftogiannis, Panos Kalnis, Vladimir B. Bajić · 2015 · Briefings in Bioinformatics
- Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancersGilson J. Sanchez, Phillip A. Richmond, Eric N. Bunker, Samuel S Karman, Joseph G. Azofeifa, Aaron T. Garnett, Quanbin Xu, Graycen E. Wheeler, Cathryn M Toomey, Qinghong Zhang et al. · 2017 · Nucleic Acids Research
- Accurate Promoter and Enhancer Identification in 127 ENCODE and Roadmap Epigenomics Cell Types and Tissues by GenoSTANZacher, Benedikt, Michel, Margaux, Schwalb, Björn, Cramer, Patrick, Tresch, Achim, Gagneur, Julien · 2017 · PLOS ONE
- LINE-1 transcription activates long-range gene expressionXiufeng Li, Luyao Bie, Yang Wang, Yaqiang Hong, Ziqiang Zhou, Yi‐Ming Fan, Xiaohan Yan, Yibing Tao, Chunyi Huang, Yongyan Zhang et al. · 2024 · Nature Genetics
- Challenges and opportunities in stroke geneticsRainer Malik, Martin Dichgans · 2018 · Cardiovascular Research
- An expanded registry of candidate cis-regulatory elementsJill E. Moore, Henry Pratt, Kaili Fan, Nishigandha N. Phalke, Jonathan Fisher, Shaimae I. Elhajjajy, Gregory Andrews, Mingshi Gao, Nicole Shedd, Yu Fu et al. · 2026 · Nature
- The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 CellsShigeru Iwata, Yohei Mikami, Hong‐Wei Sun, Stephen R. Brooks, Dragana Lj. Jankovic, Kiyoshi Hirahara, Atsushi Onodera, Han‐Yu Shih, Takeshi Kawabe, Kan Jiang et al. · 2017 · Immunity
- INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanomaBingying Zhou, Li Wang, Shu Zhang, Brian D. Bennett, Fan He, Yan Zhang, Chengliang Xiong, Leng Han, Lixia Diao, Pishun Li et al. · 2016 · Genes & Development
- Perivascular mesenchymal cells control adipose-tissue macrophage accrual in obesityBo Shan, Mengle Shao, Qianbin Zhang, Chelsea Hepler, Vivian A. Paschoal, Spencer D. Barnes, Lavanya Vishvanath, Yu An, Lin Jia, Venkat S. Malladi et al. · 2020 · Nature Metabolism
- Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1AC. Hoàng, Michael A. Hale, A. Azevedo-Pouly, H. Elsässer, Tye G. Deering, Spencer G. Willet, Fong C. Pan, M. Magnuson, C. Wright, Galvin H. Swift et al. · 2016 · Molecular and Cellular Biology
- McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genesDina Hafez, Aslıhan Karabacak Calviello, Sabrina Krueger, Yih-Chii Hwang, Li‐San Wang, Robert P. Zinzen, Uwe Ohler · 2017 · Genome biology
- Genomic regulation of transcription and RNA processing by the multitasking Integrator complexSarah A. Welsh, Alessandro Gardini · 2022 · Nature Reviews Molecular Cell Biology
- Molecular principles underlying aggressive cancersRuth Nussinov, Bengi Ruken Yavuz, Hyunbum Jang · 2025 · Signal Transduction and Targeted Therapy
- Super-enhancer hijacking LINC01977 promotes malignancy of early-stage lung adenocarcinoma addicted to the canonical TGF-β/SMAD3 pathwayTe Zhang, Wenjie Xia, Xuming Song, Qixing Mao, Xing Huang, Bing Chen, Yingkuan Liang, Hui Wang, Yuzhong Chen, Xinnian Yu et al. · 2022 · Journal of Hematology & Oncology
- From thymus to tissues and tumors: A review of T-cell biologyLaura B. Chopp, Christopher Redmond, John J. O’Shea, Daniella M. Schwartz · 2022 · Journal of Allergy and Clinical Immunology
- Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiationDan Liang, Angela L. Elwell, Nil Aygün, Oleh Krupa, Justin M. Wolter, Felix A. Kyere, Michael J. Lafferty, Kerry E. Cheek, Kenan P. Courtney, Marianna Yusupova et al. · 2021 · Nature Neuroscience
- Super-enhancer RNA m6A promotes local chromatin accessibility and oncogene transcription in pancreatic ductal adenocarcinomaRui Li, Hongzhe Zhao, Xudong Huang, Jialiang Zhang, Ruihong Bai, Lisha Zhuang, Shujuan Wen, Shaojia Wu, Quanbo Zhou, Mei Li et al. · 2023 · Nature Genetics
- Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulationWang, Chengcheng, Zhang, Taiping, Liao, Quan, Dai, Menghua, Guo, Junchao, Yang, Xinyu, Tan, Wen, Lin, Dongxin, Wu, Chen, Zhao, Yupei · 2021 · Protein & Cell
- OCT4 Acts as an Integrator of Pluripotency and Signal-Induced DifferentiationZoltán Simándi, Attila Horváth, Lyndsey C. Wright, Ixchelt Cuaranta‐Monroy, Isabella De Luca, Katalin Károlyi, Sascha Sauer, Jean‐François Deleuze, Lorraine J. Gudas, Shaun M. Cowley et al. · 2016 · Molecular Cell
- An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiationRoberto Avellino, Marije Havermans, Claudia A. J. Erpelinck-Verschueren, Mathijs Arnoud Sanders, Remco Michiel Hoogenboezem, Harmen J.G. van de Werken, Elwin J. C. Rombouts, Kirsten van Lom, Paulina M. H. van Strien, Claudia Gebhard et al. · 2016 · Blood
- Enhancers with tissue-specific activity are enriched in intronic regionsBeatrice Borsari, Pablo Villegas-Mirón, Sílvia Pérez-Lluch, Isabel Turpín, Hafid Laayouni, Alba Segarra‐Casas, Jaume Bertranpetit, Roderic Guigó, Sandra Acosta · 2021 · Genome Research
- Invited Review: Epigenetics in neurodevelopmentRyan D. Salinas, Daniel R. Connolly, Hongjun Song · 2020 · Neuropathology and Applied Neurobiology
- A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell typesYoav Ben‐Simon, Marcus J. Hooper, Sujatha Narayan, Tanya L. Daigle, Deepanjali Dwivedi, Sharon W. Way, Aaron Oster, David A. Stafford, John K. Mich, Michael J. Taormina et al. · 2025 · Cell
- Is a super-enhancer greater than the sum of its parts?Dukler, Noah, Gulko, Brad, Huang, Yi-Fei, Siepel, Adam · 2017 · Nature Genetics
- Nuclei isolation of multiple brain cell types for omics interrogationAlexi Nott, Johannes C. M. Schlachetzki, Bethany R. Fixsen, Christopher K. Glass · 2021 · Nature Protocols
- Transcriptional control by enhancers and enhancer RNAsMichael W. Lewis, Li Shen, Hector L. Franco · 2019 · Transcription
- Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophagesGregory J. Fonseca, Jenhan Tao, Emma M. Westin, Sascha H. C. Duttke, Nathanael J. Spann, Tobias Strid, Zeyang Shen, Joshua D. Stender, Mashito Sakai, Verena M. Link et al. · 2019 · Nature Communications
- Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cellsIoannis Sarropoulos, Mari Sepp, Robert Frömel, Kevin Leiss, Nils Trost, Evgeny V. Leushkin, Konstantin Okonechnikov, Piyush K. Joshi, Peter Giere, Lena M. Kutscher et al. · 2021 · Science
- New genetic and epigenetic insights into the chemokine system: the latest discoveries aiding progression toward precision medicineHanli Xu, Shuye Lin, Ziyun Zhou, Duoduo Li, Xiting Zhang, Muhan Yu, Ruoyi Zhao, Yiheng Wang, Junru Qian, Xinyi Li et al. · 2023 · Cellular and Molecular Immunology
- Human microglia maturation is underpinned by specific gene regulatory networksHan, Claudia Z., Li, Rick Z., Hansen, Emily, Trescott, Samantha, Fixsen, Bethany R., Nguyen, Celina T., Mora, Cristina M., Spann, Nathanael J., Bennett, Hunter R., Poirion, Olivier et al. · 2023 · Immunity
- Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and FunctionNathan T Lawlor, Eladio J. Márquez, Peter Orchard, Narisu Narisu, Muhammad S. Shamim, Asa Thibodeau, Arushi Varshney, Romy Kursawe, Michael R. Erdos, Matt Kanke et al. · 2019 · Cell Reports
- Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programsJanssens, Derek H., Wu, Steven J., Sarthy, Jay F., Meers, Michael P., Myers, Carrie H., Olson, James M., Ahmad, Kami, Henikoff, Steven · 2018 · Epigenetics & Chromatin
- Pregnancy, preeclampsia and maternal aging: From epidemiology to functional genomicsEliza C. Miller, Ashley Wilczek, Natalie Ann Bello, Sarah E. Tom, Ronald J. Wapner, Yousin Suh · 2021 · Ageing Research Reviews
- LDB1-mediated enhancer looping can be established independent of mediator and cohesinIvan V. Krivega, Ann Dean · 2017 · Nucleic Acids Research
- STARR‐seq and UMI‐STARR‐seq: Assessing Enhancer Activities for Genome‐Wide‐, High‐, and Low‐Complexity Candidate LibrariesChristoph Neumayr, Michaela Pagani, Alexander Stark, Cosmas D. Arnold · 2019 · Current Protocols in Molecular Biology
- Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulationJing Wang, Yue Zhao, Xiaofan Zhou, Scott W. Hiebert, Qi Liu, Yu Shyr · 2018 · BMC Genomics
- Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamicsMatthew D. Krause, Ru‐Ting Huang, David Wu, Tzu‐Pin Shentu, Devin L. Harrison, Michael Bernard Whalen, Lindsey K. Stolze, Anna Di Rienzo, Ivan P. G. Moskowitz, Mete Civelek et al. · 2018 · Proceedings of the National Academy of Sciences
- Physiological inputs regulate species-specific anatomy during embryogenesis and regenerationKelly G. Sullivan, Maya Emmons‐Bell, Michael G. Levin · 2016 · Communicative & Integrative Biology
- Topoisomerases and the regulation of neural functionPeter J. McKinnon · 2016 · Nature reviews. Neuroscience
- Epigenomes in Cardiovascular DiseaseManuel Rosa‐Garrido, Douglas J. Chapski, Thomas M. Vondriska · 2018 · Circulation Research
- Targeted Enhancer Activation by a Subunit of the Integrator ComplexElisa Barbieri, Marco Trizzino, Sarah A. Welsh, Tori A. Owens, Bruno Calabretta, Martin P Carroll, Kavitha Sarma, Alessandro Gardini · 2018 · Molecular Cell
- Deep learning of the splicing (epi)genetic code reveals a novel candidate mechanism linking histone modifications to ESC fate decisionYungang Xu, Yongcui Wang, Jiesi Luo, Weiling Zhao, Xiaobo Zhou · 2017 · Nucleic Acids Research
- The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signalingAn‐Chieh Feng, Brandon J. Thomas, Prabhat Kumar Purbey, Filipe Menegatti de Melo, Xin Liu, Allison E. Daly, Fei Sun, Jerry Hung-Hao Lo, Lijing Cheng, Michael Carey et al. · 2024 · Immunity
- ATAC-STARR-seq reveals transcription factor–bound activators and silencers within chromatin-accessible regions of the human genomeTyler J. Hansen, Emily C. Hodges · 2022 · Genome Research
- Epigenetic and metabolic programming of innate immunity in sepsisVidula Vachharajani, Charles E. McCall · 2019 · Innate Immunity
- Integrative machine learning framework for the identification of cell-specific enhancers from the human genomeShaherin Basith, Md Mehedi Hasan, Gwang Lee, Leyi Wei, Balachandran Manavalan · 2021 · Briefings in Bioinformatics
- RETRACTED: Genomic Decoding of Neuronal Depolarization by Stimulus-Specific NPAS4 HeterodimersG. Stefano Brigidi, Michael G.B. Hayes, Nathaniel P. Delos Santos, Andrea L. Hartzell, Lorane Texari, Pei-Ann Lin, Anna Bartlett, Joseph R. Ecker, Christopher W. Benner, Sven Heinz et al. · 2019 · Cell · Retracted
- Epigenetic Regulation of Kupffer Cell Function in Health and DiseaseBennett, Hunter, Troutman, Ty D., Sakai, Mashito, Glass, Christopher K. · 2021 · Frontiers in Immunology
- Glucocorticoid receptor action in metabolic and neuronal functionMichael J. Garabedian, Charles Andrew Harris, Freddy D. Jeanneteau · 2017 · F1000Research
- A shared Runx1-bound Zbtb16 enhancer directs innate and innate-like lymphoid lineage developmentAiping Mao, Isabel E. Ishizuka, Darshan N. Kasal, Malay Mandal, Albert S Bendelac · 2017 · Nature Communications
- Interplay of BAF and MLL4 promotes cell type-specific enhancer activationYoung-Kwon Park, Ji‐Eun Lee, Zhijiang Yan, Kaitlin E. McKernan, Tommy O’Haren, Weidong Wang, Weiqun Peng, Kai Ge · 2021 · Nature Communications
- Irx3 is required for postnatal maturation of the mouse ventricular conduction systemKyoung-Han Kim, Anna Rosen, Samer M. I. Hussein, Vijitha Puviindran, Adam S. Korogyi, Carmelina Chiarello, András Nagy, Chi‐chung Hui, Peter H. Backx · 2016 · Scientific Reports
- Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseasesRenate M. Hoogeveen, Matthias Nahrendorf, Niels Peter Riksen, Mihai Gheorghe Netea, Menno P.J. de Winther, Esther Lutgens, Børge Grønne Nordestgaard, Michel Neidhart, Erik S.G. Stroes, Alberico Luigi Catapano et al. · 2017 · European Heart Journal
- The interdependence of gene-regulatory elements and the 3D genomeMarit Willemijn Vermunt, Di Zhang, Gerd A. Blobel · 2018 · The Journal of Cell Biology
- Spirits in the Material World: Enhancer RNAs in Transcriptional RegulationTim Y. Hou, W. Lee Kraus · 2020 · Trends in Biochemical Sciences
- Applying CRISPR–Cas9 tools to identify and characterize transcriptional enhancersRui Lopes, Gözde Korkmaz, Reuven Agami · 2016 · Nature Reviews Molecular Cell Biology
- Dynamic assembly and activation of estrogen receptor α enhancers through coregulator switchingShino Murakami, Anusha Nagari, W. Lee Kraus · 2017 · Genes & Development
- Pancreatic Cancer Heterogeneity Can Be Explained Beyond the GenomeNatalia Anahi Juiz, Juan Iovanna, Nelson Dusetti · 2019 · Frontiers in Oncology
- Signal Integration of IFN-I and IFN-II With TLR4 Involves Sequential Recruitment of STAT1-Complexes and NFκB to Enhance Pro-inflammatory TranscriptionAnna Piaszyk-Borychowska, Lajos Széles, Attila Csermely, Hsin-Chien Chiang, Joanna Wesoły, Chien‐Kuo Lee, László Nagy, Hans A.R. Bluyssen · 2019 · Frontiers in Immunology
- Chromatin accessibility landscape of articular knee cartilage reveals aberrant enhancer regulation in osteoarthritisYe Liu, Jen-Chien Chang, Chung-Chau Hon, Naoshi Fukui, Nobuho Tanaka, Zhenya Zhang, Ming Ta Michael Lee, Aki Minoda · 2018 · Scientific Reports
- Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagyYoung Suk Yu, Hijai R. Shin, Dongha Kim, Seon Ah Baek, Seon Ah Choi, Hyejin Ahn, Amen Shamim, Ik Soo Kim, Ik Soo Kim, Kyeong Kyu Kim et al. · 2020 · Nature Communications
- A dynamic interplay of enhancer elements regulates Klf4 expression in naïve pluripotencyLiangqi Xie, Sharon E. Torigoe, Jifang Xiao, Daniel H. Mai, Li Li, Fred P. Davis, Peng Dong, Hervé Marie-Nelly, Jonathan B. Grimm, Luke D. Lavis et al. · 2017 · Genes & Development
- MAnorm2 for quantitatively comparing groups of ChIP-seq samplesShiqi Tu, Mushan Li, Fengxiang Tan, Haojie Chen, Jian Xu, David J. Waxman, Yijing Zhang, Zhen Shao · 2020 · Genome Research
- ARID1A facilitates KRAS signaling-regulated enhancer activity in an AP1-dependent manner in colorectal cancer cellsSen, Madhobi, Wang, Xin, Hamdan, Feda H., Rapp, Jacobe, Eggert, Jessica, Kosinsky, Robyn Laura, Wegwitz, Florian, Kutschat, Ana Patricia, Younesi, Fereshteh S., Gaedcke, Jochen et al. · 2019 · Clinical Epigenetics
- A Chromatin Basis for Cell Lineage and Disease Risk in the Human PancreasH. Efsun Arda, Jennifer Tsai, Yenny Rosli, Paul G. Giresi, Rita Bottino, William James Greenleaf, Howard Y. Chang, Seung K. Kim · 2018 · Cell Systems
- Colocalization analyses of genomic elements: approaches, recommendations and challengesChakravarthi Kanduri, Christoph Bock, Sveinung Gundersen, Eivind J. Hovig, Geir Kjetil Sandve · 2018 · Bioinformatics
- Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinasesCian J. Lynch, Raquel Bernad, Ana Martínez‐Val, Marta N. Shahbazi, Sandrina Nóbrega Pereira, Isabel Calvo, Carmen Blanco‐Aparicio, Carolina Tarantino, Elena Garreta, Laia Richart et al. · 2020 · Nature Cell Biology