IAP proteins: blocking the road to death's door

Cited by (1,000)

Items 501–600 of 1,000

1. Design of Small-Molecule Smac Mimetics as IAP Antagonists
   Shaomeng Wang · 2010 · Current topics in microbiology and immunology
2. Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death
   Arndt Vogel, Inge E.T. van den Berg, Muhsen Al-Dhalimy, John D. Groopman, Ching‐Nan Ou, Olga P. Ryabinina, Mihail S. Iordanov, Milton J. Finegold, Markus Grompe · 2004 · Hepatology
3. Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma
   Gavin J. Gordon, Madhubalan Mani, Gautam Maulik, Lipi Mukhopadhyay, Beow Yong Yeap, Hedy Lee Kindler, Ravi Salgia, David J. Sugarbaker, Raphael Bueno · 2007 · Cancer Chemotherapy and Pharmacology
4. New insights in flat oyster Ostrea edulis resistance against the parasite Bonamia ostreae
   Benjamín Morga, Tristan Renault, Nicole Faury, Isabelle Arzul · 2012 · Fish & Shellfish Immunology
5. Therapeutic Potential and Molecular Mechanism of a Novel, Potent, Nonpeptide, Smac Mimetic SM-164 in Combination with TRAIL for Cancer Treatment
   Jianfeng Lü, Donna McEachern, Haiying Sun, Longchuan Bai, Yuefeng Peng, Su Qiu, Rebecca S. Miller, Jinhui Liao, Yi Han, Meilan Liu et al. · 2011 · Molecular Cancer Therapeutics
6. CC Chemokine Ligand 25 Enhances Resistance to Apoptosis in CD4+ T Cells from Patients with T-Cell Lineage Acute and Chronic Lymphocytic Leukemia by Means of Livin Activation
   Zhang Qiuping, Xiong Jei, Jin Youxin, Ju Wei, Liu Chun, Wang Jin, Qun Wu, Yan Liu, Hu Chunsong, Yang Mingzhen et al. · 2004 · Cancer Research
7. Bcr-Abl-Mediated Protection from Apoptosis Downstream of Mitochondrial Cytochrome c Release
   Paula B. Deming, Zachary T. Schafer, Jessica S. Tashker, Malia B. Potts, Mohanish Deshmukh, Sally A. Kornbluth · 2004 · Molecular and Cellular Biology
8. Sensitization for γ-Irradiation–Induced Apoptosis by Second Mitochondria-Derived Activator of Caspase
   Stavros Giagkousiklidis, Meike Vogler, Mike‐Andrew Westhoff, Hubert Kasperczyk, Klaus‐Michael Debatin, Simone Fulda · 2005 · Cancer Research
9. Peptides Targeting Caspase Inhibitors
   Ingo Tamm, Martin Trepel, Marina Cardó‐Vila, Yan Sun, Kate Welsh, Edelmira Cabezas, Arnold Swatterthwait, Wadih Arap, John C. Reed, Renata Pasqualini · 2003 · Journal of Biological Chemistry
10. NF‐κB‐dependent regulation of brain‐derived neurotrophic factor in hippocampal neurons by X‐linked inhibitor of apoptosis protein
    Kairisalo, Minna, Korhonen, Laura, Sepp, Mari, Pruunsild, Priit, Kukkonen, Jyrki P., Kivinen, Jenny, Timmusk, Tõnis, Blomgren, Klas, Lindholm, Dan · 2009 · European Journal of Neuroscience
11. Inhibitor of apoptosis proteins in hematological malignancies
    Simone Fulda · 2008 · Leukemia
12. The X-Linked Inhibitor of Apoptosis Protein Enhances Survival of Murine Islet Allografts
    Annette Plesner, Peter Liston, Rusung Tan, Robert G. Korneluk, C. Bruce Verchere · 2005 · Diabetes
13. Induction of Apoptosis by Survivin Silencing through siRNA Delivery in a Human Breast Cancer Cell Line
    Hamidreza Montazeri Aliabadi, Breanne K. Landry, Parvin Mahdipoor, Hasan Uludağ · 2011 · Molecular Pharmaceutics
14. Raf and the road to cell survival: a tale of bad spells, ring bearers and detours
    Jakob Troppmair, Ulf Rüdiger Rapp · 2003 · Biochemical Pharmacology
15. Enhanced Sensitivity to Cytochrome c–Induced Apoptosis Mediated by PHAPI in Breast Cancer Cells
    Zachary T. Schafer, Amanda B. Parrish, Kevin M. Wright, Seth S. Margolis, Jeffrey R. Marks, Mohanish Deshmukh, Sally A. Kornbluth · 2006 · Cancer Research
16. Inhibition of Bcl-2 improves effect of LCL161, a SMAC mimetic, in hepatocellular carcinoma cells
    Kuen‐Feng Chen, Jing‐Ping Lin, Chung‐Wai Shiau, Wei‐Tien Tai, Chun‐Yu Liu, Hui-Chuan Yu, Pei‐Jer Chen, Ann‐Lii Cheng · 2012 · Biochemical Pharmacology
17. Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent
    Tomohisa Horibe, Masayuki Kohno, Mari Haramoto, Koji Ohara, Koji Kawakami · 2011 · Journal of Translational Medicine
18. Insulin-Like Growth Factor I: The Yin and Yang of Muscle Atrophy
    Maria F. Chacon Heszele, Stephen Russ Price · 2004 · Endocrinology
19. XAF1 Expression Is Significantly Reduced in Human Melanoma
    Kin Cheung Ng, Eric I. Campos, Magdalena Martinka, Gang Li · 2004 · Journal of Investigative Dermatology
20. Inhibitor of apoptosis proteins as targets for anticancer therapy
    Simone Fulda · 2007 · Expert Review of Anticancer Therapy
21. Survivin nuclear labeling index: a superior biomarker in superficial urothelial carcinoma of human urinary bladder
    Yin Wu, Ni Chen, Yutao Zhang, Hao Zeng, Xueqin Chen, Yongtao He, Xiaojie Wang, Qiao Zhou · 2006 · Modern Pathology
22. A Mechanistic Study of Tumor-Targeted Corrole Toxicity
    Jae Youn Hwang, Jay Lubow, David Chu, Jun Ma, Hasmik Agadjanian, Jessica D. Sims, Harry B. Gray, Zeev Gross, Daniel L. Farkas, Lali K. Medina‐Kauwe · 2011 · Molecular Pharmaceutics
23. Role of Apaf‐1, a key regulator of apoptosis, in melanoma progression and chemoresistance
    Mara Campioni, Daniele Santini, Giuseppe Tonini, Raffaele Murace, Emanuele Dragonetti, Enrico Pierluigi Spugnini, Alfonso Baldi · 2005 · Experimental Dermatology
24. Cell Arrest and Cell Death in Mammalian Preimplantation Development: Lessons from the Bovine Model
    Sandra Leidenfrost, Marc Boelhauve, Myriam Reichenbach, Tuna Güngör, Horst-Dieter Reichenbach, Fred Sinowatz, Eckhard Wolf, Felix A. Habermann · 2011 · PLoS ONE
25. Impact of Curcumin, Raspberry Extract, and Neem Leaf Extract on Rel Protein-Regulated Cell Death/Radiosensitization in Pancreatic Cancer Cells
    Jamunarani Veeraraghavan, Mohan Natarajan, Pallavi Lagisetty, Vibhudutta Awasthi, Terence S. Herman, Natarajan Aravindan · 2011 · Pancreas
26. Specific non-genetic IAP-based protein erasers (SNIPERs) as a potential therapeutic strategy
    Zonghui Ma, Ji Hoon Yu, Yifan Yu, Dailin Liang · 2021 · European Journal of Medicinal Chemistry
27. Application of XIAP Antisense to Cancer and Other Proliferative Disorders: Development of AEG35156/ GEM®640
    Eric Charles LaCasse, Ekambar R. Kandimalla, Peter D Winocour, TIM SULLIVAN, Sudhir Agrawal, John W. Gillard, Jon P. Durkin · 2005 · Annals of the New York Academy of Sciences
28. Cyclic GMP/protein kinase G type‐Iα (PKG‐Iα) signaling pathway promotes CREB phosphorylation and maintains higher c‐IAP1, livin, survivin, and Mcl‐1 expression and the inhibition of PKG‐Iα kinase activity synergizes with cisplatin in non‐small cell lung cancer cells
    Janica C. Wong, Madhavi Bathina, Ronald R. Fiscus · 2012 · Journal of Cellular Biochemistry
29. Radiation-Induced Survivin Nuclear Accumulation is Linked to DNA Damage Repair
    Gianni Capalbo, Klaus Dittmann, Christian Weiß, Sebastian Reichert, Eva Hausmann, Claus Michael Rödel, Franz Rödel · 2010 · International Journal of Radiation Oncology*Biology*Physics
30. The molecular mechanisms underlying the therapeutic resistance of cancer stem cells
    Jun-Kyum Kim, Hee-Young Jeon, Hyunggee Kim · 2014 · Archives of Pharmacal Research
31. Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy
    Nethia Mohana‐Kumaran, David S. Hill, John D. Allen, Nikolas K. Haass · 2014 · Pigment Cell & Melanoma Research
32. Protective effect of acetyl‐ l ‐carnitine on the apoptotic pathway of peripheral neuropathy
    Lorenzo Di Cesare Mannelli, Carla Ghelardini, Menotti Calvani, R. Nicolai, Luigi Mosconi, Elisa Vivoli, Alessandra Pacini, Alessandro Bartolini · 2007 · European Journal of Neuroscience
33. Baculovirus Caspase Inhibitors P49 and P35 Block Virus-Induced Apoptosis Downstream of Effector Caspase DrICE Activation in Drosophila melanogaster Cells
    Erica Lannan, Rianna Vandergaast, Paul D. Friesen · 2007 · Journal of Virology
34. Exploiting death receptor signaling pathways for tumor therapy
    Simone Fulda, Klaus‐Michael Debatin · 2004 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
35. Significant impact of survivin on myeloma cell growth
    Mathilde Romagnoli, Valérie Trichet, David Chiron, M Clément, Philippe Moreau, Régis Bataille, Sophie Barillé‐Nion · 2007 · Leukemia
36. Targeting CDK9 by wogonin and related natural flavones potentiates the anti‐cancer efficacy of the Bcl‐2 family inhibitor ABT‐263
    Gernot Polier, Marco Giaisi, Rebecca Köhler, Wolfgang W. Müller, Christoph Lutz, Eike C. Buss, Peter H. Krammer, Min Li‐Weber · 2014 · International Journal of Cancer
37. Survivin Status Affects Prognosis and Chemosensitivity in Epithelial Ovarian Cancer
    Lifeng Chen, Li‐Zhi Liang, Xiaojian Yan, Naihua Liu, Li-Hua Gong, Shi-Shi Pan, Feng Lin, Qian Zhang, Hongqin Zhao, Feiyun Zheng · 2013 · International Journal of Gynecological Cancer
38. Human Cytomegalovirus Stimulates Monocyte-to-Macrophage Differentiation via the Temporal Regulation of Caspase 3
    Gary C. T. Chan, Maciej T. Nogalski, Andrew D. Yurochko · 2012 · Journal of Virology
39. Prolonged Classical NF‐κB Activation Prevents Autophagy upon E. coli Stimulation In Vitro: A Potential Resolving Mechanism of Inflammation
    Silke Schlottmann, Franziska Buback, Bettina Stahl, Rainer Meierhenrich, Paul Walther, Michael Georgieff, Uwe Senftleben · 2008 · Mediators of Inflammation
40. Antagonist of cIAP1/2 and XIAP enhances anti-tumor immunity when combined with radiation and PD-1 blockade in a syngeneic model of head and neck cancer
    Roy Xiao, Clint Tanner Allen, Linda B. Tran, Priya Patel, So Jin Park, Zhong Chen, Carter Van Waes, Nicole Cherie Schmitt · 2018 · OncoImmunology
41. Apocytochrome c Blocks Caspase-9 Activation and Bax-induced Apoptosis
    Ángel G. Martín, Howard O. Fearnhead · 2002 · Journal of Biological Chemistry
42. Survivin is Highly Expressed and Promotes Cell Survival in Malignant Peritoneal Mesothelioma
    Nadia Zaffaroni, Aurora Costa, Marzia Pennati, Cinzia De Marco, Emanuela Affini, Maria Madeo, Roberta Erdas, Antonello Domenico Cabras, Shigeki Kusamura M. D, Dario Baratti et al. · 2007 · Analytical Cellular Pathology
43. Co-delivery of doxorubicin and plasmid by a novel FGFR-mediated cationic liposome
    Wenjing Xiao, Xiang Chen, Yang Li, Yong-Qiu Mao, Yuquan Wei, Lijuan Chen · 2010 · International Journal of Pharmaceutics
44. Apoptosis resistance inChlamydia-infected cells: a fate worse than death?
    Manu Sharma, Thomas Rudel · 2008 · FEMS Immunology & Medical Microbiology
45. Overcoming Intrinsic Resistance of Cancer Cells to CAR T-Cell Killing
    Jean Lemoine, Marco Ruella, Roch Houot · 2021 · Clinical Cancer Research
46. Proteasome inhibitor MG132 sensitizes HPV‐positive human cervical cancer cells to rhTRAIL‐induced apoptosis
    Brigitte M.T. Hougardy, John H. Maduro, Ate G.J. van der Zee, Derk Jan A. de Groot, Fiona A.J. van den Heuvel, Elisabeth G.E. de Vries, Steven de Jong · 2005 · International Journal of Cancer
47. Rapid induction of the intrinsic apoptotic pathway by L ‐glutamine starvation
    Julie C. Paquette, Paul J. Guérin, Eric R. Gauthier · 2004 · Journal of Cellular Physiology
48. Silencing of the Baculovirus Op- iap3 Gene by RNA Interference Reveals that It Is Required for Prevention of Apoptosis during Orgyia pseudotsugata M Nucleopolyhedrovirus Infection of Ld652Y Cells
    John C. Means, Israel Muro, Rollie J. Clem · 2003 · Journal of Virology
49. COMMD1 expression is controlled by critical residues that determine XIAP binding
    Maine, Gabriel N., Mao, Xicheng, Muller, Patricia A., Komarck, Christine M., Klomp, Leo W. J., Burstein, Ezra · 2009 · Biochemical Journal
50. Molecularly Targeted Radiosensitization of Human Prostate Cancer by Modulating Inhibitor of Apoptosis
    Yao Dai, Meilan Liu, Wenhua Tang, Jeffrey T. DeSano, Ezra Burstein, Mary A. Davis, Kenneth J. Pienta, Theodore Steven Lawrence, Liang Xu · 2008 · Clinical Cancer Research
51. Isoform-specific silencing of the Livin gene by RNA interference defines Livin β as key mediator of apoptosis inhibition in HeLa cells
    Irena Crnković‐Mertens, Julia Semzow, Felix Hoppe‐Seyler, Karin Butz · 2005 · Journal of Molecular Medicine
52. TGFβ-induced focal complex formation in epithelial cells is mediated by activated ERK and JNK MAP kinases and is independent of Smad4
    Yukiko Imamichi, Oliver Waidmann, Ramona Hein, Pinelopi Eleftheriou, Klaudia Giehl, André Menke · 2005 · Biological Chemistry
53. A screen for drugs that protect against the cytotoxicity of polyglutamine-expanded androgen receptor
    Federica Piccioni · 2003 · Human Molecular Genetics
54. Life and death of lymphocytes: a role in immunesenescence
    Sudhir Gupta, Houfen Su, Ruifen Bi, Sudhanshu Agrawal, Sastry V. S. Gollapudi · 2005 · Immunity & Ageing
55. Cyclin-dependent kinase inhibitor 3 is overexpressed in hepatocellular carcinoma and promotes tumor cell proliferation
    Chunyang Xing, Haiyang Xie, Lin Zhou, Wuhua Zhou, Wu Zhang, Songming Ding, Bajin Wei, Xiaobo Yu, Rong Su, Shusen Zheng · 2012 · Biochemical and Biophysical Research Communications
56. Nanoparticle-Mediated Delivery of SiRNA for Effective Lung Cancer Therapy
    Young‐Dong Kim, Tae‐Eun Park, Bijay Singh, Sushila Maharjan, Yun‐Jaie Choi, Pill‐Hoon Choung, Rohidas B. Arote, Chong‐Su Cho · 2015 · Nanomedicine
57. Inhibition of Apoptosis in Cryptosporidium parvum -Infected Intestinal Epithelial Cells Is Dependent on Survivin
    Jin Liu, Shinichiro Enomoto, Cheryl A. Lancto, Mitchell S. Abrahamsen, Mark S. Rutherford · 2008 · Infection and Immunity
58. HIV-Specific CD8+ T Cells Exhibit Markedly Reduced Levels of Bcl-2 and Bcl-xL
    Constantinos Petrovas, Yvonne M. Mueller, Ioannis D. Dimitriou, Paul M. Bojczuk, Karam Mounzer, James Witek, John D. Altman, Peter D. Katsikis · 2004 · The Journal of Immunology
59. Sensitization of pancreatic carcinoma cells for γ-irradiation-induced apoptosis by XIAP inhibition
    Stavros Giagkousiklidis, Sri HariKrishna Vellanki, Klaus‐Michael Debatin, Simone Fulda · 2007 · Oncogene
60. Akt-dependent Expression of NAIP-1 Protects Neurons against Amyloid-β Toxicity
    Sylvain Lesné, C. Gabriel, Deirdre A. Nelson, Eileen White, Eric T. MacKenzie, Denis Vivien, Alain Buisson · 2005 · Journal of Biological Chemistry
61. Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase
    Eric L. Marderstein, Brian T. Bucher, Zhong Guo, Xuesheng Feng, Kaye M. Reid, David A. Geller · 2003 · Surgery
62. Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradation
    Wen‐Hsien Liu, Huey-Wen Hsiao, Wen‐I Tsou, Ming‐Zong Lai · 2007 · The EMBO Journal
63. Differential regulation of survivin expression and apoptosis by vitamin D3 compounds in two isogenic MCF-7 breast cancer cell sublines
    Fengzhi Li, Xiang Ling, Huayi Huang, Lisa E. Brattain, Pasha Apontes, Jianguo Wu, Lise Binderup, Michael G. Brattain · 2004 · Oncogene
64. Translocation of the inhibitor of apoptosis protein c-IAP1 from the nucleus to the Golgi in hematopoietic cells undergoing differentiation: a nuclear export signal-mediated event
    Stéphanie Plenchette, Séverine Cathelin, Cédric Rébé, Sophie Launay, Sylvain Ladoire, Olivier Sordet, Tibor Ponnelle, Najet Debili, Thi-Hai Phan, Rose Ann Padua et al. · 2004 · Blood
65. Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2–MALT1 in MALT lymphoma
    Zilin Nie, Ming‐Qing Du, Linda M. McAllister‐Lucas, Peter C. Lucas, Nathanael G. Bailey, Cory M. Hogaboam, Megan S. Lim, Kojo S.J. Elenitoba‐Johnson · 2015 · Nature Communications
66. Tumor suppressor XAF1 induces apoptosis, inhibits angiogenesis and inhibits tumor growth in hepatocellular carcinoma
    Li Zhu, Dong Mei Shi, Qiang Dai, Xiao Jiao Cheng, Wei Yao, Ping-Hu Sun, Yan Fei Ding, Min Min Qiao, Yun Wu, Shi Hu Jiang et al. · 2014 · Oncotarget
67. Verteporfin inhibits cell proliferation and induces apoptosis in different subtypes of breast cancer cell lines without light activation
    Changran Wei, Xiangqi Li · 2020 · BMC Cancer
68. Drosophila Omi, a mitochondrial‐localized IAP antagonist and proapoptotic serine protease
    Madhavi Challa-Malladi, Srinivas Malladi, Brett J. Pellock, Douglas Dresnek, Shankar Varadarajan, Yuhui Whitney Yin, Kristin White, Shawn B. Bratton · 2007 · The EMBO Journal
69. Regulation of cell survival and death during Flavivirus infections
    Sounak Ghosh Roy · 2014 · World Journal of Biological Chemistry
70. Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase
    Anne Hamacher‐Brady, Seungmo Choe, Jacomina Krijnse Locker, Nathan Ryan Brady · 2014 · Cell Death and Differentiation
71. X Chromosome-linked Inhibitor of Apoptosis Regulates Cell Death Induction by Proapoptotic Receptor Agonists
    Eugene E. Varfolomeev, Bruno Alicke, J. Michael Elliott, Kerry Zobel, Kristina A. West, Harvey Wong, Justin M. Scheer, Avi Ashkenazi, Stephen E. Gould, Wayne J. Fairbrother et al. · 2009 · Journal of Biological Chemistry
72. The GRIMs: a new interface between cell death regulation and interferon/retinoid induced growth suppression
    Dhananjaya V. Kalvakolanu · 2004 · Cytokine & Growth Factor Reviews
73. Effective response of doxorubicin-sensitive and -resistant breast cancer cells to combinational siRNA therapy
    Hamidreza Montazeri Aliabadi, Robert A. Maranchuk, Cezary Kucharski, Parvin Mahdipoor, Judith C. Hugh, Hasan Uludağ · 2013 · Journal of Controlled Release
74. Survivin Expression in Endometrial Carcinoma:
    Judit Pallarés, José‐Luis Martínez‐Guitarte, Xavier Dolcet, David Llobet‐Navàs, Montserrat Rué, Jos� M. Palacios, Jaime Prat, Xavier Matías‐Guiu · 2005 · International Journal of Gynecological Pathology
75. Translational Regulation of X-Linked Inhibitor of Apoptosis Protein by Interleukin-6
    Yoko Yamagiwa, Carla Beth Marienfeld, Fanyin Meng, Martin Holčı́k, Tushar C. Patel · 2004 · Cancer Research
76. Toward system-level understanding of baculovirus–host cell interactions: from molecular fundamental studies to large-scale proteomics approaches
    Francisca Monteiro, Nuno Carinhas, Manuel J.T. Carrondo, Vicente Bernal, Paula M. Alves · 2012 · Frontiers in Microbiology
77. Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER)
    Nobumichi Ohoka, Osamu Ujikawa, Kenichiro Shimokawa, Tomoya Sameshima, Norihito Shibata, Takayuki Hattori, Hiroshi Nara, Nobuo Cho, Mikihiko Naito · 2018 · Chemical and Pharmaceutical Bulletin
78. ARTS and Siah Collaborate in a Pathway for XIAP Degradation
    Jason B. Garrison, Ricardo G. Correa, Motti Gerlic, Kenneth W. Yip, Andreas H. Krieg, Craig M. Tamble, Ranxin Shi, Kate Welsh, Srinivas Duggineni, Ziwei Huang et al. · 2010 · Molecular Cell
79. HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells
    Keiko Sekine, Yanyan Hao, Yasuyuki Suzuki, Ryōsuke Takahashi, Takashi Tsuruo, Mikihiko Naito · 2005 · Biochemical and Biophysical Research Communications
80. Increased expression of Apaf-1 and procaspase-3 and the functionality of intrinsic apoptosis apparatus in non-small cell lung carcinoma
    Evzen Krepela, Jan Procházka, Xuan Liu, Pavel Fiala, Zdeněk Kinkor · 2004 · Biological Chemistry
81. Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists
    Simone Fulda · 2013 · Oncogene
82. Inhibitor of apoptosis proteins as therapeutic targets in multiple myeloma
    Vijay G. Ramakrishnan, Utkarsh Painuly, Teresa K. Kimlinger, Janine Haug, S. Vincent Rajkumar, Shaji Kunnathu Kumar · 2014 · Leukemia
83. Contribution of caspase-8 to apoptosis of axotomized rat retinal ganglion cells in vivo
    Jochen Hans Weishaupt, Ricarda Diem, Pawel Kermer, Stanisław Krajewski, John C. Reed, Mathias Bähr · 2003 · Neurobiology of Disease
84. Targeting off-target effects: endoplasmic reticulum stress and autophagy as effective strategies to enhance temozolomide treatment
    Yichun He, Jing Su, Beiwu Lan, Yufei Gao, Jingxia Zhao · 2019 · OncoTargets and Therapy
85. Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway
    Yu Li, Hongyan Ding, Leihong Liu, Yuxiang Song, Xiliang Du, Shibin Feng, Xichun Wang, Xiaobing Li, Zhe Wang, Xinwei Li et al. · 2020 · Frontiers in Cell and Developmental Biology
86. Cell Survival and Cell Death at the Intersection of Autophagy and Apoptosis: Implications for Current and Future Cancer Therapeutics
    Nicole Bata, Nicholas D. P. Cosford · 2021 · ACS Pharmacology & Translational Science
87. Potent, Orally Bioavailable Diazabicyclic Small-Molecule Mimetics of Second Mitochondria-Derived Activator of Caspases
    Yuefeng Peng, Haiying Sun, Zaneta Nikolovska‐Coleska, Su Qiu, Chao‐Yie Yang, Jianfeng Lü, Qian Cai, Yi Han, Sanmao Kang, Dajun Yang et al. · 2008 · Journal of Medicinal Chemistry
88. Wnt3 gene expression promotes tumor progression in non-small cell lung cancer
    Nariyasu Nakashima, Dage Liu, Chenglong Huang, Masaki Ueno, Xia Zhang, Hiroyasu Yokomise · 2011 · Lung Cancer
89. Caspase activation and apoptosis in response to proteasome inhibitors
    Clare J. Henderson, Emanuela Aleo, Alessandra Fontanini, Roberta Maestro, Gabriela Paroni, Claudio Brancolini · 2005 · Cell Death and Differentiation
90. On the TRAIL of a new therapy for leukemia
    Scott H. Kaufmann, David P. Steensma · 2005 · Leukemia
91. Apoptosis regulation by autophagy gene 5
    Shída Yousefi, Hans‐Uwe Simon · 2007 · Critical Reviews in Oncology/Hematology
92. Rapamycin-mediated mTOR inhibition attenuates survivin and sensitizes glioblastoma cells to radiation therapy
    Arunkumar Anandharaj, Senthilkumar Cinghu, Woo‐Yoon Park · 2011 · Acta Biochimica et Biophysica Sinica
93. Lessons learned from cancer may help in the treatment of pulmonary hypertension
    Serge Adnot · 2005 · Journal of Clinical Investigation
94. A Novel Ubiquitin Fusion System Bypasses the Mitochondria and Generates Biologically Active Smac/DIABLO
    Allison M. Hunter, Dan Kottachchi, Jennifer Lewis, Colin S. Duckett, Robert G. Korneluk, Peter Liston · 2003 · Journal of Biological Chemistry
95. The anti-apoptotic livin gene is an important determinant for the apoptotic resistance of non-small cell lung cancer cells
    Irena Crnković‐Mertens, Thomas Muley, Michael A. Meister, Bettina Hartenstein, Julia Semzow, Karin Butz, Felix Hoppe‐Seyler · 2006 · Lung Cancer
96. Apoptosis as an instrument in cardiovascular development
    Robert Eugen Poelmann, Adriana C. Gittenberger–de Groot · 2005 · Birth Defects Research Part C Embryo Today Reviews
97. Anti‐proliferative and apoptosis inducing effect of nimbolide by altering molecules involved in apoptosis and IGF signalling via PI3K/Akt in prostate cancer (PC‐3) cell line
    Raja Singh Paulraj, Ramachandran Arunkumar, Velayutham Sivakamasundari, Govindaraj Sharmila, Elumalai Perumal, Elayapillai Suganthapriya, A. Brindha Mercy, Kalimuthu Senthilkumar, Jegadeesan Arunakaran · 2013 · Cell Biochemistry and Function
98. Survivin expression and serum levels in pancreatic cancer
    He Dong, Dongmeng Qian, Yaqiu Wang, Lingsheng Meng, Dong Chen, Xiangyu Ji, Wei Feng · 2015 · World Journal of Surgical Oncology
99. The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo
    Natalia Edison, Dotan Zuri, Inbal Maniv, Bavat Bornstein, Tali Lev, Yossi Gottfried, Stav Kemeny, M Garcia-Fernandez, Juliana Kagan, Sarit Larisch · 2011 · Cell Death and Differentiation
100. MiR-330-Mediated Regulation of SH3GL2 Expression Enhances Malignant Behaviors of Glioblastoma Stem Cells by Activating ERK and PI3K/AKT Signaling Pathways
     Yilong Yao, Yixue Xue, Jun Ma, Chao Shang, Ping Wang, Libo Liu, Wenjing Liu, Zhen Li, Shengtao Qu, Zhiqing Li et al. · 2014 · PLoS ONE