NF‐κB‐dependent regulation of brain‐derived neurotrophic factor in hippocampal neurons by X‐linked inhibitor of apoptosis protein

Trk Receptors: Roles in Neuronal Signal Transduction

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Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non‐NMDA glutamate receptors.

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From Synapse to Nucleus: Calcium-Dependent Gene Transcription in the Control of Synapse Development and Function

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IAPs, RINGs and ubiquitylation

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Roles for NF-κB in nerve cell survival, plasticity, and disease

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BDNF-induced TrkB activation down-regulates the K+–Cl− cotransporter KCC2 and impairs neuronal Cl− extrusion

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Cerebral Interleukin-6 is Neuroprotective during Permanent Focal Cerebral Ischemia in the Rat

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XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1–TAK1 in the BMP signaling pathway

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XIAP: Apoptotic brake and promising therapeutic target

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Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF

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Discovery of Embelin as a Cell-Permeable, Small-Molecular Weight Inhibitor of XIAP through Structure-Based Computational Screening of a Traditional Herbal Medicine Three-Dimensional Structure Database

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Endoplasmic Reticulum Stress Inhibition Protects against Excitotoxic Neuronal Injury in the Rat Brain

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XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization

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Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6.

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Interleukin-6 and Interleukin-1 receptor antagonist in cerebrospinal fluid from patients with recent tonic–clonic seizures

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X-linked Inhibitor of Apoptosis Protein Functions as a Cofactor in Transforming Growth Factor-β Signaling

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X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia–ischemia

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IAPs are essential for GDNF-mediated neuroprotective effects in injured motor neurons in vivo

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Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemia

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BHLHB2 Controls Bdnf Promoter 4 Activity and Neuronal Excitability

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Nuclear factor‐κB regulates seizure threshold and gene transcription following convulsant stimulation

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X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-κB activation

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Hippocalcin protects against caspase-12-induced and age-dependent neuronal degeneration

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X chromosome‐linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia‐ischemia through up‐regulation of mitochondrial antioxidants

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Cardiotrophin-1 induces interleukin-6 synthesis in human monocytes

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IκB-Mediated Inhibition of Virus-Induced Beta Interferon Transcription

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p75 Neurotrophin receptor mediates neurotrophin activation of NF‐kappa B and induction of iNOS expression in P19 neurons

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X-linked inhibitor of apoptosis protein regulates human interleukin-6 in umbilical vein endothelial cells via stimulation of the nuclear factor-kappaB and MAP kinase signaling pathways.

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Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

Lima Giacobbo, B., Doorduin, J., Klein, H. C., Dierckx, R. A. J. O., Bromberg, E., & de Vries, E. F. J. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1283-6 · Cited by 750 · see citing works

Brain-Derived Neurotrophic Factor in Alzheimer’s Disease and Its Pharmaceutical Potential

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Inflammatory cytokine-associated depression

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Brain-Derived Neurotrophic Factor Serum Levels and Genotype: Association with Depression during Interferon-α Treatment

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Brothers in Arms: ProBDNF/BDNF and sAPPα/Aβ-Signaling and Their Common Interplay with ADAM10, TrkB, p75NTR, Sortilin, and sorLA in the Progression of Alzheimer’s Disease

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Reciprocal Regulation of Very Low Density Lipoprotein Receptors (VLDLRs) in Neurons by Brain-derived Neurotrophic Factor (BDNF) and Reelin

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Anti-Neuroinflammatory, Protective Effects of the Synthetic Microneurotrophin BNN-20 in the Advanced Dopaminergic Neurodegeneration of “Weaver” Mice

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Faculty Opinions recommendation of Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP).

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Inhibitor of apoptosis protein XIAP and malignant tumor

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Disturbed XIAP and XAF1 Expression Balance Is an Independent Prognostic Factor in Gastric Adenocarcinomas

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Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP)

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Research Progress of the Inhibitor-of-protein XIAP

Wang, J. (2003) · Journal of Hebei University