The DOI matches its Crossref record; 158 of the 158 references it cites were found in a registry or an index.
IAP proteins: blocking the road to death's door
Abstract
The 'inhibitor of apoptosis' (IAP) gene family, which was discovered less than a decade ago, encodes a group of structurally related proteins that, in addition to their ability to suppress apoptotic cell death, are involved in an increasing number of seemingly unrelated cellular functions. Here, we review the functional and structural properties of this fascinating group of proteins, and of several recently identified IAP-binding factors that regulate IAP function.
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“Cytosolic SMAC precipitates apoptosis by associating with members of the inhibitor of apoptosis (IAP) protein family, including X-linked inhibitor of apoptosis (XIAP) [162, 163, 181].”
From Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018. (2018) · cites this paper as [181]
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Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation · doi:10.1038/s41418-017-0012-4 · Cited by 6,680
Self-citationSmad-dependent and Smad-independent pathways in TGF-β family signalling
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The integrated stress response
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Metadata
- Authors
- Salvesen, G. S., & Duckett, C. S.
- Affiliations
- Sanford Burnham Prebys Medical Discovery Institute (US)
- University of Michigan (US)
- Corresponding author
- Duckett, Colin S.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2002-06
- Volume
- 3
- Issue
- 6
- Pages
- 401-410
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W1492587973
- Semantic Scholar
- 37eaa4d6440b014eff358aeee58f3772e77e8934
- Cited by
- 1,756
- References
- 157
- Citations by year
- 2026: 12 · 2025: 8 · 2024: 20 · 2023: 25 · 2022: 26 · 2021: 32 · 2020: 46 · 2019: 48 · 2018: 42 · 2017: 43 · 2016: 43 · 2015: 59 · 2014: 63 · 2013: 90 · 2012: 81
- FWCI
- 9.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Molecular Cell Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cell death mechanisms and regulation
- Health Sciences › Medicine › Oncology › Cancer-related Molecular Pathways
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ubiquitin and proteasome pathways
- Keywords
- inhibitor of apoptosis proteins, apoptosis, cell death regulation, protein structure
- MeSH terms
- Animals, Binding Sites, Gene Expression Regulation, Humans, Proteins, Cysteine Proteinase Inhibitors, Apoptosis, Insect Proteins, Inhibitor of Apoptosis Proteins
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