Microbiological effects of sublethal levels of antibiotics

Antibiotic resistance is ancient

D’Costa, V. M., King, C. E., Kalan, L., Morar, M., Sung, W. W. L., Schwarz, C., Froese, D., Zazula, G., Calmels, F., Debruyne, R., et al. (2011) · Nature · doi:10.1038/nature10388 · Cited by 2,720

SOS response promotes horizontal dissemination of antibiotic resistance genes

Beaber, J. W., Hochhut, B., & Waldor, M. K. (2004) · Nature · doi:10.1038/nature02241 · Cited by 1,186

Metabolite-enabled eradication of bacterial persisters by aminoglycosides

Allison, K. R., Brynildsen, M. P., & Collins, J. J. (2011) · Nature · doi:10.1038/nature10069 · Cited by 1,025

Bacterial charity work leads to population-wide resistance

Lee, H. H., Molla, M. N., Cantor, C. R., & Collins, J. J. (2010) · Nature · doi:10.1038/nature09354 · Cited by 638

Ready for a world without antibiotics? The Pensières Antibiotic Resistance Call to Action

Carlet, J., Jarlier, V., Harbarth, S., Voss, A., Goossens, H., Pittet, D., & Forum, T. P. O. T. 3. W. H.-A. I. (2012) · Antimicrobial Resistance and Infection Control · doi:10.1186/2047-2994-1-11 · Cited by 350

Small molecules: the missing link in the central dogma

Schreiber, S. L. (2005) · Nature Chemical Biology · doi:10.1038/nchembio0705-64 · Cited by 306

Ecological effects of antibiotics on natural ecosystems: A review

Grenni, P., Ancona, V., & Barra Caracciolo, A. (2018) · Microchemical Journal · doi:10.1016/j.microc.2017.02.006 · Cited by 1,257

Fecal pollution can explain antibiotic resistance gene abundances in anthropogenically impacted environments

Karkman, A., Pärnänen, K., & Larsson, D. G. J. (2019) · Nature Communications · doi:10.1038/s41467-018-07992-3 · Cited by 628

Co-occurrence of antibiotic and metal resistance genes revealed in complete genome collection

Li, L.-G., Xia, Y., & Zhang, T. (2017) · The ISME Journal · doi:10.1038/ismej.2016.155 · Cited by 528

Sub-inhibitory concentrations of heavy metals facilitate the horizontal transfer of plasmid-mediated antibiotic resistance genes in water environment *

Zhang, Y., Gu, A. Z., Cen, T., Li, X., He, M., Li, D., & Chen, J. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.01.032 · Cited by 472

Evolution of high-level resistance during low-level antibiotic exposure

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Antibiotic use in food animals worldwide, with a focus on Africa: Pluses and minuses

Van, T. T. H., Yidana, Z., Smooker, P. M., & Coloe, P. J. (2020) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2019.07.031 · Cited by 451

Resistance Toward Chlorhexidine in Oral Bacteria – Is There Cause for Concern?

Cieplik, F., Jakubovics, N. S., Buchalla, W., Maisch, T., Hellwig, E., & Al-Ahmad, A. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00587 · Cited by 424

Deciphering of microbial community and antibiotic resistance genes in activated sludge reactors under high selective pressure of different antibiotics

Zhao, R., Feng, J., Liu, J., Fu, W., Li, X., & Li, B. (2019) · Water Research · doi:10.1016/j.watres.2018.12.034 · Cited by 383

Antibiotics and common antibacterial biocides stimulate horizontal transfer of resistance at low concentrations

Jutkina, J., Marathe, N. P., Flach, C.-F., & Larsson, D. G. J. (2018) · Science of The Total Environment · doi:10.1016/j.scitotenv.2017.10.312 · Cited by 381

Both silver ions and silver nanoparticles facilitate the horizontal transfer of plasmid-mediated antibiotic resistance genes

Lu, J., Wang, Y., Jin, M., Yuan, Z., Bond, P., & Guo, J. (2020) · Water Research · doi:10.1016/j.watres.2019.115229 · Cited by 380

Stormwater loadings of antibiotic resistance genes in an urban stream

Garner, E., Benitez, R., von Wagoner, E., Sawyer, R., Schaberg, E., Hession, W. C., Krometis, L.-A. H., Badgley, B. D., & Pruden, A. (2017) · Water Research · doi:10.1016/j.watres.2017.06.046 · Cited by 131

How can we define “optimal microbiota?”: a comparative review of structure and functions of microbiota of animals, fish, and plants in agriculture

Ikeda-Ohtsubo, W., Brugman, S., Warden, C. H., Rebel, J. M. J., Folkerts, G., & Pieterse, C. M. J. (2018) · Frontiers in Nutrition · doi:10.3389/fnut.2018.00090 · Cited by 115

Dissecting the effects of antibiotics on horizontal gene transfer: analysis suggests a critical role of selection dynamics

Lopatkin, A. J., Sysoeva, T. A., & You, L. (2016) · BioEssays · doi:10.1002/bies.201600133 · Cited by 83

Microplastics affect nitrogen cycling and antibiotic resistance genes transfer of sediment

Zeng, Q., Xiang, J., Yang, C., Wu, J., Li, Y., Sun, Y., Liu, Q., Shi, S., & Gong, Z. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.140193 · Cited by 73

Biological Mitigation of Antibiotic Resistance Gene Dissemination by Antioxidant-Producing Microorganisms in Activated Sludge Systems

Ren, C.-Y., Wu, E.-L., Hartmann, E. M., & Zhao, H.-P. (2021) · Environmental Science & Technology · doi:10.1021/acs.est.1c04641 · Cited by 73

Antifungal Tolerance and Resistance Emerge at Distinct Drug Concentrations and Rely upon Different Aneuploid Chromosomes

Yang, F., Scopel, E. F. C., Li, H., Sun, L.-L., Kawar, N., Cao, Y.-B., Jiang, Y.-Y., & Berman, J. (2023) · mBio · doi:10.1128/mbio.00227-23 · Cited by 62

Antimicrobial-resistant microorganisms and their genetic determinants in stormwater: a systematic review

Hamilton, K. A., Garner, E., Joshi, S., Ahmed, W., Ashbolt, N., Medema, G., & Pruden, A. (2020) · Current Opinion in Environmental Science & Health · doi:10.1016/j.coesh.2020.02.012 · Cited by 32

Poverty and Community-Acquired Antimicrobial Resistance with Extended-Spectrum β-Lactamase–Producing Organisms, Hyderabad, India

Alsan, M., Kammili, N., Lakshmi, J., Xing, A., Khan, A., Rani, M., Kolli, P., Relman, D. A., & Owens, D. K. (2018) · Emerging Infectious Diseases · doi:10.3201/eid2408.171030 · Cited by 31