Cited by 845Eating Disorders and BehaviorsRegulation of Appetite and ObesityNutrition, Health and Food Behavior

The DOI matches its Crossref record; 172 of the 173 references it cites were found in a registry or an index.

New insights into symptoms and neurocircuit function of anorexia nervosa

Open access

Kaye, Walter H., Fudge, Julie L., Paulus, Martin·2009·Nature Reviews Neuroscience

Open this paper in CoChat — free account Open PDF

Abstract

Individuals with anorexia nervosa have a relentless preoccupation with dieting and weight loss that results in severe emaciation and sometimes death. It is controversial whether such symptoms are secondary to psychosocial influences, are a consequence of obsessions and anxiety or reflect a primary disturbance of brain appetitive circuits. New brain imaging technology provides insights into ventral and dorsal neural circuit dysfunction - perhaps related to altered serotonin and dopamine metabolism - that contributes to the puzzling symptoms found in people with eating disorders. For example, altered insula activity could explain interoceptive dysfunction, and altered striatal activity might shed light on altered reward modulation in people with anorexia nervosa.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1038/nrn2682

Cites

172 of 172 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
How do you feel — now? The anterior insula and human awareness
(Bud) Craig, A. D. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2555 · Cited by 6,657 · cited 2×
“…of the entire body 143 and is crucial for the instantiation of the ‘self’ because it provides the link between cognitive and affective processes and the current body state 140–142, It is thought that altered interoceptive awareness might be a precipitating and reinforcing factor in AN 10,146–148 .”
Central nervous system control of food intake
Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451
How do you feel? Interoception: The sense of the physiological condition of the body
Craig, A. D. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn894 · Cited by 6,006
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
Berridge, K. C., & Robinson, T. E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00019-8 · Cited by 4,127
Neural systems supporting interoceptive awareness
Critchley, H. D., Wiens, S., Rotshtein, P., Öhman, A., & Dolan, R. J. (2004) · Nature Neuroscience · doi:10.1038/nn1176 · Cited by 3,406 · cited 2×
“…of the entire body 143 and is crucial for the instantiation of the ‘self’ because it provides the link between cognitive and affective processes and the current body state 140–142, It is thought that altered interoceptive awareness might be a precipitating and reinforcing factor in AN 10,146–148 .”
Contributions of anterior cingulate cortex to behaviour
Devinsky, O., Morrell, M. J., & Vogt, B. A. (1995) · Brain · doi:10.1093/brain/118.1.279 · Cited by 3,377
Separate neural systems value immediate and delayed monetary rewards
McClure, S. M., Laibson, D. I., Loewenstein, G., & Cohen, J. D. (2004) · Science · doi:10.1126/science.1100907 · Cited by 3,089
Anterior Cingulate Conflict Monitoring and Adjustments in Control
Kerns, J. G., Cohen, J. D., MacDonald, A. W., Cho, R. Y., Stenger, V. A., & Carter, C. S. (2004) · Science · doi:10.1126/science.1089910 · Cited by 2,891
Risk and maintenance factors for eating pathology: A meta-analytic review.
Stice, E. M. (2002) · Psychological Bulletin · doi:10.1037/0033-2909.128.5.825 · Cited by 2,710

Flagged first, then by citations

Show all 173 references

1 of the 173 references couldn’t be matched to a known paper.

Sorted by citations

Items 401–500 of 845

Pathway-specific GABAergic inhibition contributes to the gain of resilience against anorexia-like behavior of adolescent female mice
Aoki, C. J., & Santiago, A. N. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.990354 · Cited by 20
Sex and exercise interact to alter the expression of anabolic androgenic steroid-induced anxiety-like behaviors in the mouse
Onakomaiya, M. M., Porter, D. M., Oberlander, J. G., & Henderson, L. (2014) · Hormones and Behavior · doi:10.1016/j.yhbeh.2014.04.008 · Cited by 20
Major Depression and Avoidant Personality Traits in Eating Disorders
Daga, G. A., Gramaglia, C. M., Bailer, U. F., S., B., Marzola, E., & Fassino, S. (2011) · Psychotherapy and Psychosomatics · doi:10.1159/000324761 · Cited by 20
Do reward and punishment sensitivity change after treatment for anorexia nervosa?
Harrison, A., Sternheim, L. C., O'Hara, C., Oldershaw, A., & Schmidt, U. H. (2016) · Personality and Individual Differences · doi:10.1016/j.paid.2016.02.051 · Cited by 20
Computer aided sentiment analysis of anorexia nervosa patients’ vocabulary
Spińczyk, D., Nabrdalik, K., & Rojewska, K. (2018) · BioMedical Engineering OnLine · doi:10.1186/s12938-018-0451-2 · Cited by 20
Three daily intraperitoneal injections of sub‐anesthetic ketamine ameliorate activity‐based anorexia vulnerability of adult female mice
Goodwin‐Groen, S., Dong, Y., & Aoki, C. J. (2023) · International Journal of Eating Disorders · doi:10.1002/eat.24036 · Cited by 19
What can Cognitive Neuroscience Teach us about Anorexia Nervosa?
Kidd, A., & STEINGLASS, J. E. (2012) · Current Psychiatry Reports · doi:10.1007/s11920-012-0285-8 · Cited by 19
Eating disorders
Herpertz‐Dahlmann, B., Holtkamp, K., & Konrad, K. (2012) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52002-9.00026-7 · Cited by 19
The Clinical Significance of Posterior Insular Volume in Adolescent Anorexia Nervosa
Zucker, N. L., Kragel, P. A., Wagner, H. R., Keeling, L. A., Mayer, E. A., Wang, J., Kang, M. S., Merwin, R. M., Simmons, W. K., & LaBar, K. S. (2017) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000510 · Cited by 20
Exploration of Shared Genetic Architecture Between Subcortical Brain Volumes and Anorexia Nervosa
PGC-ED, Walton, E., ENIGMA Genetics Working Group, Hibar, D. P., Yılmaz, Z., Jahanshad, N., Cheung, J. T. P., Batury, V.-L., Seitz, J., Bulik, C. M., et al. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1439-4 · Cited by 21
Insensitivity to Losses: A Core Feature in Patients With Anorexia Nervosa?
Verharen, J. P. H., Danner, U. N., Schröder, S. S., Aarts, E., Elburg, A. A. V., & Adan, R. A. H. (2019) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2019.05.001 · Cited by 21
Reduced Environmental Stimulation in Anorexia Nervosa: An Early-Phase Clinical Trial
Khalsa, S. S., Moseman, S. E., Yeh, H., Upshaw, V., Persac, B., Breese, E., Lapidus, R. C., Chappelle, S. D., Paulus, M. P., & Feinstein, J. S. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.567499 · Cited by 21
Self-citation
Dissection of the Genetic Association between Anorexia Nervosa and Obsessive–Compulsive Disorder at the Network and Cellular Levels
Song, W., Wang, W., Yu, S., & Lin, G. N. (2021) · Genes · doi:10.3390/genes12040491 · Cited by 22
Cognitions and Emotions in Eating Disorders
Siep, N., Jansen, A. T. M., Havermans, R. C., & Roefs, A. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_82 · Cited by 19
Associations between neural correlates of visual stimulus processing and set-shifting in ill and recovered women with anorexia nervosa
Sultson, H., van Meer, F., Sanders, N. M., Elburg, A. A. V., Danner, U. N., Hoek, H. W., Adan, R. A. H., & Smeets, P. A. M. (2016) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2016.07.004 · Cited by 19
Self-Deception and the Second Factor: How Desire Causes Delusion in Anorexia Nervosa
Gadsby, S. (2018) · Erkenntnis · doi:10.1007/s10670-018-0039-z · Cited by 19
Ketamine and Zinc: Treatment of Anorexia Nervosa Via Dual NMDA Receptor Modulation
Mitchell, J., Hermens, D. F., Bennett, M. R., Can, A., & Lagopoulos, J. (2023) · CNS Drugs · doi:10.1007/s40263-022-00984-4 · Cited by 18
Recovery from anorexia nervosa includes neural compensation for negative body image
Pruis, T. A., Keel, P. K., & Janowsky, J. S. (2012) · International Journal of Eating Disorders · doi:10.1002/eat.22034 · Cited by 18
Beyond the Activity-Based Anorexia Model: Reinforcing Values of Exercise and Feeding Examined in Stressed Adolescent Male and Female Mice
Hurel, I., Redon, B., Scocard, A., Malézieux, M., Marsicano, G., & Chaouloff, F. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00587 · Cited by 18
Basal ganglia volume and shape in anorexia nervosa
Leppänen, J., Cardi, V., Sedgewick, F., Treasure, J. L., & Tchanturia, K. (2019) · Appetite · doi:10.1016/j.appet.2019.104480 · Cited by 19
Anxiety disorders predict fasting to control weight: A longitudinal large cohort study of adolescents
Lloyd, E. C., Haase, A. M., Zerwas, S. C., & Micali, N. (2019) · European Eating Disorders Review · doi:10.1002/erv.2714 · Cited by 18
Increased plasma asprosin levels in patients with drug-naive anorexia nervosa
Hu, Y., Xu, Y., Zheng, Y., Kang, Q., Lou, Z., Liu, Q., Chen, H., Ji, Y., Guo, L., Chen, C., et al. (2020) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-020-00845-3 · Cited by 18
Evaluation of spontaneous regional brain activity in weight-recovered anorexia nervosa
Seidel, M., Geisler, D., Borchardt, V., King, J. A., Bernardoni, F., Jaite, C., Roessner, V., Calhoun, V. D., Walter, M., & Ehrlich, S. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-01081-0 · Cited by 18
Vicarious ratings of self vs. other-directed social touch in women with and recovered from Anorexia Nervosa
Bellard, A., Trotter, P. D., McGlone, F. P., & Cazzato, V. (2022) · Scientific Reports · doi:10.1038/s41598-022-17523-2 · Cited by 18
The 5-HTTLPR Confers Susceptibility to Anorexia Nervosa in Han Chinese: Evidence from a Case-Control and Family-Based Study
Chen, J., Kang, Q., Jiang, W., Fan, J., Zhang, M., Yu, S., & Zhang, C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119378 · Cited by 18
The relationship between exercise addiction, eating disorders, and insecure attachment styles among recreational exercisers
Lev-Arey, D., Sagi, A., & Blatt, A. (2023) · Journal of Eating Disorders · doi:10.1186/s40337-023-00855-3 · Cited by 16
New understandings meet old treatments: putting a contemporary face on established protocols
Byrne, S. M., & Fursland, A. (2024) · Journal of Eating Disorders · doi:10.1186/s40337-024-00983-4 · Cited by 21
Attention networks in adolescent anorexia nervosa
Weinbach, N., Sher, H., Lock, J., & Henik, A. (2017) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-017-1057-0 · Cited by 17
Structural brain changes in severe and enduring anorexia nervosa: A multimodal magnetic resonance imaging study of gray matter volume, cortical thickness, and white matter integrity
Mishima, R., Isobe, M., Noda, T., Tose, K., Kawabata, M., Noma, S., & Murai, T. (2021) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2021.111393 · Cited by 17
Psychopathological and Neurobiological Overlap Between Anorexia Nervosa and Self-Injurious Behavior: A Narrative Review and Conceptual Hypotheses
Oudijn, M. S., Linders, J., Mocking, R. J. T., Lok, A., Elburg, A. A. V., & Denys, D. A. J. P. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.756238 · Cited by 17
Diagnostic Concordance between Research and Clinical-Based Assessments of Psychiatric Comorbidity in Anorexia Nervosa
Longo, P., Toppino, F., Martini, M., Panero, M., Bacco, C. D., Marzola, E., & Daga, G. A. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11247419 · Cited by 17
Comparative validity of the chinese versions of the bulimic inventory test edinburgh and eating attitudes test for DSM‐IV eating disorders among high school dance and nondance students in taiwan
Tseng, M. M., Fang, D., & Lee, M. (2013) · International Journal of Eating Disorders · doi:10.1002/eat.22183 · Cited by 17
Alexithymia in anorexia and bulimia: Ubiquitous and primary trait?
Amianto, F., Bertorello, A., Migliore, F., Daga, G. A., & Fassino, S. (2016) · Cogent Psychology · doi:10.1080/23311908.2016.1185994 · Cited by 17
The absent body in psychiatric diagnosis, treatment, and research
Stinson, C. (2017) · Synthese · doi:10.1007/s11229-017-1507-8 · Cited by 18
A tasting experiment comparing food and nutritional supplement in anorexia nervosa
Marzola, E., Cavallo, F., Pradella, P., Brustolin, A., & Daga, G. A. (2020) · Appetite · doi:10.1016/j.appet.2020.104789 · Cited by 17
Role of spontaneous physical activity in prediction of susceptibility to activity based anorexia in male and female rats
Perez‐Leighton, C. E., Grace, M. K., Billington, C. J., & Kotz, C. M. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.06.001 · Cited by 17
Implicit sequence learning in juvenile anorexia nervosa: neural mechanisms and the impact of starvation
Firk, C., Mainz, V., Schulte‐Rüther, M., Fink, G. R., Herpertz‐Dahlmann, B., & Konrad, K. (2015) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12384 · Cited by 16
Hunger and disinhibition but not cognitive restraint are associated with central norepinephrine transporter availability
Bresch, A., Rullmann, M., Luthardt, J., Becker, G., Patt, M., Ding, Y.-S., Hilbert, A., Sabri, O., & Hesse, S. (2017) · Appetite · doi:10.1016/j.appet.2017.06.020 · Cited by 16
Randomized controlled trial of cognitive remediation therapy in adolescent inpatients with anorexia nervosa: Neuropsychological outcomes
Herbrich, L., Bentz, L. K., Correll, C. U., Kappel, V., & van Noort, B. M. (2022) · European Eating Disorders Review · doi:10.1002/erv.2921 · Cited by 16
Sex Differences Precipitating Anorexia Nervosa in Females: The Estrogen Paradox and a Novel Framework for Targeting Sex-Specific Neurocircuits and Behavior
Keating, C. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_99 · Cited by 16
Similarities and differences between eating disorders and obese patients in a virtual environment for normalizing eating patterns
Perpiñá, C., & Roncero, M. (2016) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2016.02.012 · Cited by 16
A factor analysis of the meanings of anorexia nervosa: intrapsychic, relational, and avoidant dimensions and their clinical correlates
Marzola, E., Panepinto, C., Delsedime, N., Amianto, F., Fassino, S., & Daga, G. A. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0894-6 · Cited by 16
Set-shifting in adolescents with weight-restored anorexia nervosa and their unaffected family members
Weinbach, N., Bohon, C., & Lock, J. (2019) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2019.02.022 · Cited by 16
Large-Scale Exploration of Whole-Brain Structural Connectivity in Anorexia Nervosa: Alterations in the Connectivity of Frontal and Subcortical Networks
Lloyd, E. C., Foerde, K., Muratore, A. F., Aw, N., Semanek, D., STEINGLASS, J. E., & Posner, J. E. (2021) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2022.06.002 · Cited by 15
Deficits in response inhibition on varied levels of demand load in anorexia nervosa: an event-related potentials study
Yue, L., Tang, Y., Kang, Q., Wang, Q., Wang, J., & Chen, J. (2018) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-018-0558-2 · Cited by 15
Body image disturbances, fear and associations with the amygdala in anorexia nervosa
Burkert, N. T., Koschutnig, K., Ebner, F., & Freidl, W. (2019) · Wiener klinische Wochenschrift · doi:10.1007/s00508-018-1440-y · Cited by 15
Dopaminergic Activity and Exercise Behavior in Anorexia Nervosa
Gorrell, S., Collins, A. G. E., Grange, D. L., & Yang, T. T. (2020) · OBM Neurobiology · doi:10.21926/obm.neurobiol.2001053 · Cited by 16
Electrodermal Response to Mirror Exposure in Relation to Subjective Emotional Responses, Emotional Competences and Affectivity in Adolescent Girls With Restrictive Anorexia and Healthy Controls
Knejzlíková, T., Světlák, M., Malatincová, T., Román, R., Chládek, J., Najmanová, J., Theiner, P., Linhartová, P., & Kašpárek, T. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.673597 · Cited by 15
The cerebellum gains weight: A systematic review of alterations in cerebellar volume and cerebro-cerebellar functional alterations in individuals with eating disorders
Siciliano, L., Olivito, G., & Leggio, M. G. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104863 · Cited by 15
Animal Models of Eating Disorder Traits
Kas, M. J., & Adan, R. A. H. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_84 · Cited by 15
Escaping the Golden Cage: Animal Models of Eating Disorders in the Post–Diagnostic and Statistical Manual Era
Lutter, M. L., Croghan, A. E., & Cui, H. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.02.006 · Cited by 16
The potential of calibrated fMRI in the understanding of stress in eating disorders
Wierenga, C. E., Lavender, J. M., & Hays, C. C. (2018) · Neurobiology of Stress · doi:10.1016/j.ynstr.2018.08.006 · Cited by 17
Distorted body image in women and men suffering from Anorexia Nervosa – a literature review
Kostecka, B., Kordyńska, K., Murawiec, S., & Kucharska, K. (2019) · Archives of Psychiatry and Psychotherapy · doi:10.12740/app/102833 · Cited by 15
Anorexia nervosa, neuroimaging research, and the contextual salience of food cues: The food approach–avoidance conundrum
Murray, S. B., & Strigo, I. A. (2018) · International Journal of Eating Disorders · doi:10.1002/eat.22883 · Cited by 14
Is Serum BDNF Altered in Acute, Short- and Long-Term Recovered Restrictive Type Anorexia Nervosa?
Steinhäuser, J. L., King, J. A., Tam, F. I., Seidel, M., Biemann, R., Wronski, M., Geisler, D., Roessner, V., & Ehrlich, S. (2021) · Nutrients · doi:10.3390/nu13020432 · Cited by 14
A Narrative Review on the Neurocognitive Profiles in Eating Disorders and Higher Weight Individuals: Insights for Targeted Interventions
Krug, I., Dang, A. B., Lu, E., Ooi, W. L., Portingale, J., & Miles, S. (2024) · Nutrients · doi:10.3390/nu16244418 · Cited by 16
The impact of theory of mind and neurocognition on delusionality in anorexia nervosa
Konstantakopoulos, G., Ioannidi, N., Patrikelis, P., & Gonidakis, F. (2020) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2020.1786504 · Cited by 16
Just like fireworks in my brain – a Swedish interview study on experiences of emotions in female patients with eating disorders
Petersson, S., Gullbing, L., & Perseius, K. (2021) · Journal of Eating Disorders · doi:10.1186/s40337-021-00371-2 · Cited by 14
Decision-Making, Impulsiveness and Temperamental Traits in Eating Disorders.
Ciberti, A., Cavalletti, M., Palagini, L., Mariani, M. G., Dell’Osso, L., Mauri, M., Maglio, A., Mucci, F., Marazziti, D., & Miniati, M. (2020) · PubMed Central · doi:10.36131/cnfioritieditore20200401 · Cited by 14
Associations Between Eating Attitudes, Mental Health, and Sexual Dysfunction during Pregnancy
Gerges, S., Obeïd, S., & Hallit, S. R. (2022) · Journal of Sex & Marital Therapy · doi:10.1080/0092623x.2022.2149937 · Cited by 14
Cognitive flexibility and DSM-5 severity criteria for eating disorders: assessing drive for thinness and duration of illness as alternative severity variables
Mora‐Maltas, B., Lucas, I., Granero, R., Vintró‐Alcaraz, C., Miranda‐Olivos, R., Baenas, I., Sánchez, I., Toro, J. J., Sánchez‐González, J., Krug, I., et al. (2023) · Journal of Eating Disorders · doi:10.1186/s40337-023-00875-z · Cited by 14
Physical activity recommendations for adolescents with anorexia nervosa: An existing protocol based on physical activity risk
Scott, L., & Blyderveen, S. V. (2014) · Mental health and physical activity · doi:10.1016/j.mhpa.2014.09.001 · Cited by 14
Interacting Neural Processes of Feeding, Hyperactivity, Stress, Reward, and the Utility of the Activity-Based Anorexia Model of Anorexia Nervosa
Ross, R., Mandelblat-Cerf, Y., & Verstegen, A. M. J. (2016) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000111 · Cited by 15
Voluntary Wheel Running Exercise Evoked by Food-Restriction Stress Exacerbates Weight Loss of Adolescent Female Rats But Also Promotes Resilience by Enhancing GABAergic Inhibition of Pyramidal Neurons in the Dorsal Hippocampus
Chowdhury, T. G., Wable, G. S., Chen, Y.-W., Tateyama, K., Yu, I., Wang, J., Reyes, A. D., & Aoki, C. J. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy283 · Cited by 14
Targeting Emotion Circuits with Deep Brain Stimulation in Refractory Anorexia Nervosa
Lipsman, N., & Lozano, A. M. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.244 · Cited by 14
Evaluation of Insight, Self-Esteem, and Body Satisfaction in Eating Disorders
Şenay, O., & Yücel, B. (2022) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000001598 · Cited by 13
Is decision-making impairment an endophenotype of anorexia nervosa?
Lodovico, L. D., Versini, A., Lachatre, M., Marcheselli, J., Ramoz, N., & Gorwood, P. A. P. M. (2022) · European Psychiatry · doi:10.1192/j.eurpsy.2022.2327 · Cited by 15
Ketamine ameliorates activity-based anorexia of adolescent female mice through changes in GluN2B-containing NMDA receptors at postsynaptic cytoplasmic locations of pyramidal neurons and interneurons of medial prefrontal cortex
Li, J., Temizer, R., Chen, Y.-W., & Aoki, C. J. (2024) · Brain Structure and Function · doi:10.1007/s00429-023-02740-w · Cited by 13
Provocation of Symmetry/Ordering Symptoms in Anorexia nervosa: A Functional Neuroimaging Study
Suda, M., Brooks, S. J., Giampietro, V., Uher, R., Mataix‐Cols, D., Brammer, M. J., Williams, S., Treasure, J. L., & Campbell, I. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0097998 · Cited by 13
Altered microstructure of brain white matter in females with anorexia nervosa: a diffusion tensor imaging study
Hu, S., Feng, H., Xu, T., Zhang, H., Zhao, Z., Lai, J., Xu, D., & Xu, Y. (2017) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s144972 · Cited by 14
Neurobiological signature of intimacy in anorexia nervosa
Maier, S. J., Spiegelberg, J., van Zutphen, L., Zeeck, A., van Elst, L. T., Hartmann, A., Holovics, L., Reinert, E., Sandholz, A., Lahmann, C., et al. (2019) · European Eating Disorders Review · doi:10.1002/erv.2663 · Cited by 13
Brain structure alterations associated with weight changes in young females with anorexia nervosa: a case series
Fuglset, T. S., Endestad, T., Landrø, N. I., & Rø, Ø. (2014) · Neurocase · doi:10.1080/13554794.2013.878728 · Cited by 13
Verifying Feighner’s Hypothesis; Anorexia Nervosa Is Not a Psychiatric Disorder
Södersten, P., Brodin, U., Zandian, M., & Bergh, C. E. K. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.02110 · Cited by 13
Activity-Based Anorexia, an Animal Model of Anorexia Nervosa for Investigating Brain Plasticity Underlying the Gain of Resilience
Aoki, C. J. (2020) · Neuromethods · doi:10.1007/978-1-0716-0924-8_15 · Cited by 13
Anorexia Nervosa and Estrogen Receptors
Ramoz, N., Versini, A., & Gorwood, P. A. P. M. (2013) · Vitamins and hormones · doi:10.1016/b978-0-12-410473-0.00006-4 · Cited by 13
Structural and functional brain correlates of altered taste processing in anorexia nervosa: A systematic review
Kot, E., Kucharska, K., Monteleone, A. M., & Monteleone, P. (2019) · European Eating Disorders Review · doi:10.1002/erv.2713 · Cited by 13
The potential application of event‐related potentials to enhance research on reward processes in eating disorders
Forester, G., Schaefer, L. M., Dodd, D. R., & Johnson, J. S. (2022) · International Journal of Eating Disorders · doi:10.1002/eat.23821 · Cited by 12
Mediation models of anxiety and depression between temperament and drive for thinness and body dissatisfaction in anorexia nervosa
Jérolon, A., Perduca, V., Delsedime, N., Daga, G. A., & Marzola, E. (2022) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-022-01397-4 · Cited by 12
GABAergic interneurons’ feedback inhibition of dorsal raphe-projecting pyramidal neurons of the medial prefrontal cortex suppresses feeding of adolescent female mice undergoing activity-based anorexia
Du, M., Santiago, A. N., Akiz, C., & Aoki, C. J. (2022) · Brain Structure and Function · doi:10.1007/s00429-022-02507-9 · Cited by 12
Repeated stress triggers seeking of a starvation-like state in anxiety-prone female mice
Kucukdereli, H., Amsalem, O., Pottala, T., Lim, M., Potgieter, L., Hasbrouck, A., Lutas, A., & Andermann, M. L. (2024) · Neuron · doi:10.1016/j.neuron.2024.03.027 · Cited by 12
An Investigation of the Factor Structure of the Beck Depression Inventory‐II in Anorexia Nervosa
Fuss, S., Trottier, K., & Carter, J. (2014) · European Eating Disorders Review · doi:10.1002/erv.2338 · Cited by 12
Neural Substrates Underlying Interactions between Appetite Stress and Reward
Menzies, J. R. W., Skibicka, K. P., Dickson, S. L., & Leng, G. (2012) · Obesity Facts · doi:10.1159/000338237 · Cited by 12
Nothing Tastes as Good as Skinny Feels: the Neurobiology of Anorexia Nervosa
Kaye, W. H., Wierenga, C. E., Bailer, U. F., Simmons, A. N., & Bischoff‐Grethe, A. (2014) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.120413 · Cited by 12
Self-citation
Evaluating the potential of deep brain stimulation for treatment-resistant anorexia nervosa
Lipsman, N., Woodside, D. B., & Lozano, A. M. (2013) · Handbook of clinical neurology · doi:10.1016/b978-0-444-53497-2.00022-x · Cited by 12
To eat or not to eat: A role for ghrelin and LEAP2 in eating disorders?
Tolle, V., du Montcel, C. T., Mattioni, J., Schéle, E., Viltart, O., & Dickson, S. L. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104045 · Cited by 11
Gastrointestinal Microbiota & Symptoms of Depression and Anxiety in Anorexia Nervosa—A Re-Analysis of the MICROBIAN Longitudinal Study
Ketel, J., Bruguera, M. B., Auchter, G., Cuntz, U., Zipfel, S., Enck, P., & Mack, I. (2024) · Nutrients · doi:10.3390/nu16060891 · Cited by 12
The role of gut microbiota in modulating brain structure and psychiatric disorders: A Mendelian randomization study
Ye, Z., Gao, Y., Yuan, J., Chen, F., Xu, P., & Liu, W. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121292 · Cited by 16
Neuropathological investigation of patients with prolonged anorexia nervosa
Kawakami, I., Iritani, S., Riku, Y., Umeda, K., Takase, M., Ikeda, K., Niizato, K., Arai, T., Yoshida, M., Oshima, K., et al. (2022) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13340 · Cited by 11
No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Weinert, T., Bernardoni, F., King, J. A., Steding, J., Boehm, I., Mannigel, M., Ritschel, F., Zepf, F. D., Roessner, V., & Ehrlich, S. (2022) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-022-01414-8 · Cited by 11
Restoring connection in the face of disconnection: an integrative approach to understanding and treating anorexia nervosa
Tantillo, M., Sanftner, J. L., & Hauenstein, E. J. (2013) · Advances in Eating Disorders · doi:10.1080/21662630.2013.742980 · Cited by 12
Neuroscience of Adolescent Anorexia Nervosa: Implications for Family-Based Treatment (FBT)
Mysliwiec, R. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00418 · Cited by 11
Testing of a model for risk factors for eating disorders and higher weight among emerging adults: Baseline evaluation
Fuller‐Tyszkiewicz, M., Rodgers, R. F., Maïano, C., Mellor, D. J., Sicilia, Á., Markey, C. H., Aimé, A., Dion, J., Pietrabissa, G., Coco, G. L., et al. (2022) · Body Image · doi:10.1016/j.bodyim.2022.01.007 · Cited by 13
Predicting the restrictive eating, exercise, and weight monitoring compulsions of anorexia nervosa
Lloyd, E. C., Øverås, M., Rø, Ø., Verplanken, B., & Haase, A. M. (2019) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-019-00674-z · Cited by 11
Correlation of Functional Magnetic Resonance Imaging Response to Visual Food Stimuli With Clinical Measures in Adolescents With Restrictive Eating Disorders
Ziv, A., O’Donnell, J. M., Ofei-Tenkorang, N. A., Meisman, A. R., Nash, J. K., Mitan, L. P., DiFrancesco, M. W., Altaye, M., & Gordon, C. M. (2020) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2020.01.028 · Cited by 11
Insular Cell Integrity Markers Linked to Weight Concern in Anorexia Nervosa—An MR-Spectroscopy Study
Maier, S. J., Nickel, K., Perlov, E., Kukies, A., Zeeck, A., van Elst, L. T., Endres, D., Spieler, D., Holovics, L., Hartmann, A., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9051292 · Cited by 11
Development and validation of the Premorbid Childhood Traits Questionnaire (PCT-Q) in eating disorders
Marzola, E., Fassino, S., Migliaretti, G., Daga, G. A., & Kaye, W. H. (2019) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-019-00748-y · Cited by 10
Self-citation
Attachment status is associated with grey matter recovery in adolescent anorexia nervosa: Findings from a longitudinal study
Lenhart, L., Gander, M., Steiger, R., Dabkowska‐Mika, A., Mangesius, S., Haid-Stecher, N., Fuchs, M., Buchheim, A., Sevecke, K., & Gizewski, E. R. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15614 · Cited by 10
Activity-Based Anorexia Alters Hypothalamic POMC Expression in Male Rats
Pinos, H., Sánchez-Serrano, R., Carrillo, B., Fernández‐García, J. M., García-Úbeda, R., de Paz, A., López-Tolsa, G. E., Vidal, P., Gutiérrez-Ferre, V. E., Pellón, R., et al. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.114055 · Cited by 10
Full of Your Self: How Eating Disorder Symptoms Encode a Relational History
Ferguson, H., & Mendelsohn, S. (2011) · International Journal of Psychoanalytic Self Psychology · doi:10.1080/15551024.2011.582934 · Cited by 10
The use of cognitive remediation therapy on a child adolescent eating disorder unit: Patients and therapist perspectives
Giombini, L., Turton, R., Turco, M., Nesbitt, S., & Lask, B. D. (2016) · Clinical Child Psychology and Psychiatry · doi:10.1177/1359104516657859 · Cited by 11

Authors: Kaye, W. H., Fudge, J. L., & Paulus, M.
Affiliations: University of California San Diego (US)
University of Rochester Medicine (US)
Corresponding author: Kaye, Walter H.
ORCID: Kaye, Walter H.
Fudge, Julie L.
Paulus, Martin
Venue: Nature Reviews Neuroscience
Publisher: Springer Science and Business Media LLC
Published: 2009-07-15
Volume: 10
Issue: 8
Pages: 573-584
ISSN: 1471-003X (ISSN-L)
1471-0048
DOI: 10.1038/nrn2682
PMC: PMC13038070
OpenAlex: W2067637201
Cited by: 843
References: 173
Citations by year: 2026: 38 · 2025: 37 · 2024: 38 · 2023: 38 · 2022: 45 · 2021: 47 · 2020: 49 · 2019: 58 · 2018: 43 · 2017: 59 · 2016: 57 · 2015: 52 · 2014: 58 · 2013: 77 · 2012: 45
FWCI: 6.52
Type: journal article
Language: en
Open access: green
pmc.ncbi.nlm.nih.gov
Licence: www.springer.com/tdm (tdm)
Locations: Nature reviews. Neuroscience (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Louis and Harold Price Foundation
Wellcome Trust (066122)
U.S. Public Health Service (018307, 001894, 020687, 016663, 046001, 063291, 042984)
National Institute of Mental Health (R01MH063291)
Topics: Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
Keywords: anorexia nervosa, eating disorders, neurocircuitry, neurotransmitter systems, serotonin, dopamine, reward processing, interoception, insula, striatum, appetite regulation, neuroimaging
MeSH terms: Animals, Anorexia Nervosa, Brain, Brain Mapping, Diagnostic Imaging, Dopamine, Humans, Neural Pathways, Serotonin

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

New insights into symptoms and neurocircuit function of anorexia nervosa

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks