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Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β

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Conformational equilibria and intrinsic affinities define integrin activation

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An αv‐RGD Integrin Inhibitor Toolbox: Drug Discovery Insight, Challenges and Opportunities

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Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus

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Energy landscape differences among integrins establish the framework for understanding activation

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Distinct recognition of complement iC3b by integrins α X β 2 and α M β 2

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Prodomain–growth factor swapping in the structure of pro-TGF-β1

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Matters of context guide future research in TGFβ superfamily signaling

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Integrin Alpha v Beta 6 (αvβ6) and Its Implications in Cancer Treatment

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New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins

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Alpha-v–containing integrins are host receptors for the Plasmodium falciparum sporozoite surface protein, TRAP

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Leukocyte integrin α L β 2 headpiece structures: The αI domain, the pocket for the internal ligand, and concerted movements of its loops

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Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability

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Molecular Modeling Insights into the Structure and Behavior of Integrins: A Review

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Ammonium trichloro [1,2-ethanediolato-O,O′]-tellurate cures experimental visceral leishmaniasis by redox modulation of Leishmania donovani trypanothione reductase and inhibiting host integrin linked PI3K/Akt pathway

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From a Helix to a Small Cycle: Metadynamics‐Inspired αvβ6 Integrin Selective Ligands

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Atypical interactions of integrin α V β 8 with pro-TGF-β1

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Discovery of (S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic αvβ6 Integrin Inhibitor for the Inhaled Treatment of Idiopathic Pulmonary Fibrosis

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Insights into Protein–Ligand Interactions in Integrin Complexes: Advances in Structure Determinations

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Low-affinity integrin states have faster ligand-binding kinetics than the high-affinity state

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An engineered AAV targeting integrin alpha V beta 6 presents improved myotropism across species

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General structural features that regulate integrin affinity revealed by atypical αVβ8

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Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease

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Polymerizing laminins in development, health, and disease

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Cross-Talk between the TGF-β and Cell Adhesion Signaling Pathways in Cancer

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Integrin Engagement by the Helical RGD Motif of the Helicobacter pylori CagL Protein Is Regulated by pH-induced Displacement of a Neighboring Helix

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Peptides, proteins and nanotechnology: a promising synergy for breast cancer targeting and treatment

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Exploring the role of ITGB6: fibrosis, cancer, and other diseases

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Exploring Integrin α5β1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights From Comprehensive Multicenter Preclinical Studies

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Specificity of TGF-β1 signal designated by LRRC33 and integrin αVβ8

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Autonomous conformational regulation of β 3 integrin and the conformation-dependent property of HPA-1a alloantibodies

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TGFβ: Signaling Blockade for Cancer Immunotherapy

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Molecular View on the i RGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles

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Adhesion of Several Cell Lines to Helicobacter pylori CagL Is Mediated by Integrin αVβ6 via an RGDLXXL Motif

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Characterisation of a novel, high affinity and selective αvβ6 integrin RGD-mimetic radioligand

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New Therapeutic Targets for Hepatic Fibrosis in the Integrin Family, α8β1 and α11β1, Induced Specifically on Activated Stellate Cells

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Active Search for Computer‐aided Drug Design

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Design, Synthesis, and Targeted Delivery of Fluorescent 1,2,4-Triazole–Peptide Conjugates to Pediatric Brain Tumor Cells

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N -Methylation of iso DGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent

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The β8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development

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Extracellular citrullination inhibits the function of matrix associated TGF-β

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Investigating the Interaction of Cyclic RGD Peptidomimetics with αVβ6 Integrin by Biochemical and Molecular Docking Studies

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Fibrillin microfibril structure identifies long-range effects of inherited pathogenic mutations affecting a key regulatory latent TGFβ-binding site

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Cryo-Electron Microscopy Structure of the αIIbβ3-Abciximab Complex

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