Web-based weight loss in primary care: a randomized controlled trial
Open accessAbstract
Evidence is lacking regarding effective and sustainable weight loss approaches for use in the primary care setting. We conducted a 12-week randomized controlled trial to evaluate the short-term efficacy of a web-based weight loss intervention among 101 primary care patients with obesity and hypertension. Patients had access to a comprehensive website that used a moderate-intensity weight loss approach designed specifically for web-based implementation. Patients also participated in four (two in-person and two telephonic) counseling sessions with a health coach. Intent-to-treat analysis showed greater weight loss at 3 months (-2.56 kg; 95% CI -3.60, -1.53) among intervention participants (-2.28 +/- 3.21 kg), relative to usual care (0.28 +/- 1.87 kg). Similar findings were observed among intervention completers (-3.05 kg; 95% CI -4.24, -1.85). High rates of participant retention (84%) and website utilization were observed, with the greatest weight loss found among those with a high frequency of website logins (quartile 4 vs. 1: -4.16 kg; 95% CI -1.47, -6.84). The intervention's approach promoted moderate weight loss at 12 weeks, though greater weight loss was observed among those with higher levels of website utilization. Efficacious web-based weight loss interventions can be successfully offered in the primary care setting.
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Bennett 2010 stated that research staff collecting evaluation data were blinded to randomization status.
“Bennett 2010 stated that research staff collecting evaluation data were blinded to randomization status.”
From Interactive computer-based interventions for weight loss or weight maintenance in overweight or obese people (2012) · cites this paper as Bennett 2010
After 10 to 14 weeks of treatment, the five individual trials with weight loss measurements at three months showed that participants in the computer-based intervention groups lost more weight than participants in the minimal intervention control groups (MD -2.5 kg, 95% CI -3.4 to -1.6, P < 0.00001; 430 participants; five trials).
“After 10 to 14 weeks of treatment, the five individual trials with weight loss measurements at three months (Bennett 2010; Morgan 2009; Morgan 2011; Schroder 2010; Threlfall 1984) showed that participants in the computer-based intervention groups lost more weight than participants in the minimal intervention control groups (mean difference (MD) −2.5 kg (95% confidence interval (CI) −3.4 to −1.6),”
From Interactive computer-based interventions for weight loss or weight maintenance in overweight or obese people (2012) · cites this paper as Bennett 2010
One trial (Bennett 2010) did not describe the method of randomization, but did state that assignments were enclosed in nontransparent envelopes, and the review judged that allocation was adequately concealed.
“One trial (Bennett 2010) did not describe the method of randomization, but did state that assignments were enclosed in nontransparent envelopes, and we therefore judged that allocation was adequately concealed.”
From Interactive computer-based interventions for weight loss or weight maintenance in overweight or obese people (2012) · cites this paper as Bennett 2010
Several trials (Bennett 2010; Hunter 2008; Morgan 2009; Morgan 2011; Wylie-Rosett 2001) tested for and demonstrated statistically significant positive associations between amount of computer use and amount of weight loss in the intervention group.
“Several trials (Bennett 2010; Hunter 2008; Morgan 2009; Morgan 2011; Wylie-Rosett 2001) tested for and demonstrated statistically significant positive associations between amount of computer use, measured in a variety of ways, and amount of weight loss in the intervention group.”
From Interactive computer-based interventions for weight loss or weight maintenance in overweight or obese people (2012) · cites this paper as Bennett 2010
In the one study reporting percent weight loss at three months (Bennett 2010), participants in the computer intervention lost 3% more body weight (or approximately 2.5 kg) compared to participants in the control group (MD -3.0%, 95% CI -4.1 to -1.9, P < 0.00001; 101 participants, one trial).
“In the one study reporting percent weight loss at three months (Bennett 2010), participants in the computer intervention lost 3% more body weight (or approximately 2.5 kg) compared to participants in the control group (MD −3.0% (95% CI −4.1 to −1.9); P < 0.00001; 101 participants, one trial, Analysis 1.4).”
From Interactive computer-based interventions for weight loss or weight maintenance in overweight or obese people (2012) · cites this paper as Bennett 2010
Of the 15 studies that mention adapting the design of the intervention to increase adherence, 8 studies do so without any theoretical basis or reference.
“Of the 15 studies that mention adapting the design of the intervention to increase adherence, 8 studies do so without any theoretical basis or reference [64-71]”
From Persuasive System Design Does Matter: a Systematic Review of Adherence to Web-based Interventions (2012) · cites this paper as [67]
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- Authors
- Bennett, G. G., Herring, S. J., Puleo, E., Stein, E. K., Emmons, K. M., & Gillman, M. W.
- Affiliations
- Harvard University (US)
- Harvard Pilgrim Health Care (US)
- University of Massachusetts Amherst (US)
- Dana-Farber Cancer Institute (US)
- Corresponding author
- Bennett, Gary G.
- Venue
- Obesity
- Publisher
- Wiley
- Published
- 2010-02
- Volume
- 18
- Issue
- 2
- Pages
- 308-313
- ISSN
- 1930-7381 (ISSN-L)
- 1930-739X
- PMC
- PMC3710670
- OpenAlex
- W1991807359
- Cited by
- 202
- References
- 32
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 8 · 2023: 6 · 2022: 10 · 2021: 11 · 2020: 10 · 2019: 9 · 2018: 19 · 2017: 16 · 2016: 7 · 2015: 19 · 2014: 31 · 2013: 17 · 2012: 15
- FWCI
- 20.52
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Obesity (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5k05ca124415-05)
- U.S. Public Health Service (#5 T32 HP11001-19)
- National Cancer Institute (K22CA126992, K05-CA124415, 1K05CA124415-01A1)
- Topics
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Health Professions › Pharmacy › Obesity and Health Practices
- Keywords
- hypertension, primary care, health coaching, website utilization, participant retention, weight loss efficacy, digital health
- MeSH terms
- Counseling, Female, Goals, Health Promotion, Humans, Hypertension, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Obesity, Patient Compliance, Primary Health Care, Self Care, Time Factors, Weight Loss, Health Behavior, Treatment Outcome, Internet
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