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CLIC4 and CLIC1 bridge plasma membrane and cortical actin network for a successful cytokinesis

Kagıalı, Z. C. Ü., Saner, N., Akdag, M., Şanal, E., Değirmenci, B. S., Mollaoglu, G., & Özlü, N. (2019) · Life Science Alliance · doi:10.26508/lsa.201900558 · Cited by 33 · see citing works

Ezrin gone rogue in cancer progression and metastasis: An enticing therapeutic target

Barik, G. K., Sahay, O., Paul, D., & Santra, M. K. (2022) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2022.188753 · Cited by 34 · see citing works

Cancer Biomarker Detection by Surface Plasmon Resonance Biosensors

Reddy, P. J., Sadhu, S., Ray, S., & Srivastava, S. (2011) · Clinics in Laboratory Medicine · doi:10.1016/j.cll.2011.11.002 · Cited by 33 · see citing works

Inhibition of ezrin causes PKCα-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells

Jeong, J., Choi, J., Kim, W., Dann, P. R., Takyar, F. M., Gefter, J. V., Friedman, P. A., & Wysolmerski, J. J. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.004143 · Cited by 33 · see citing works

Ez-Metastasizing: The Crucial Roles of Ezrin in Metastasis

Buenaventura, R. G. M., Merlino, G. T., & Yu, Y. (2023) · Cells · doi:10.3390/cells12121620 · Cited by 32 · see citing works

miR-96 suppresses renal cell carcinoma invasion via downregulation of Ezrin expression

Yu, N., Fu, S., Liu, Y., Xu, Z., Liu, Y., Hao, J., Wang, B., & Zhang, A. (2015) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-015-0224-8 · Cited by 32 · see citing works

Activated ezrin controls MISP levels to ensure correct NuMA polarization and spindle orientation

Kschonsak, Y. T., & Hoffmann, I. (2018) · Journal of Cell Science · doi:10.1242/jcs.214544 · Cited by 32 · see citing works

MicroRNA regulation of critical retinal pigment epithelial functions

Du, S. W., & Palczewski, K. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.10.008 · Cited by 32 · see citing works

Mechanosensitive Ion Channels

Hope, J. M., Greenlee, J. D., & King, M. R. (2018) · The Cancer Journal · doi:10.1097/ppo.0000000000000312 · Cited by 31 · see citing works

The cell surface mucin podocalyxin regulates collective breast tumor budding

Graves, M. L., Cipollone, J., Austin, P., Bell, E. M., Nielsen, J. S., Gilks, C. B., McNagny, K. M., & Roskelley, C. D. (2016) · Breast Cancer Research · doi:10.1186/s13058-015-0670-4 · Cited by 31 · see citing works

RASSF4 Overexpression Inhibits the Proliferation, Invasion, EMT, and Wnt Signaling Pathway in Osteosarcoma Cells

Zhang, M., Wang, D., Zhu, T., & Yin, R. (2017) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.3727/096504016x14719078133447 · Cited by 31 · see citing works

Genomic Complexity of Osteosarcoma and Its Implication for Preclinical and Clinical Targeted Therapies

Schott, C. R., Shah, A. T., & Sweet-Cordero, A. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-43085-6_1 · Cited by 30 · see citing works

MicroRNAs and osteosarcoma: Potential targets for inhibiting metastasis and increasing chemosensitivity

Soghli, N., Ferns, G. A., Sadeghsoltani, F., Qujeq, D., Yousefi, T., & Vaghari‐Tabari, M. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115094 · Cited by 30 · see citing works

The Ezrin Metastatic Phenotype Is Associated with the Initiation of Protein Translation

Briggs, J., Ren, L., Nguyen, R., Chakrabarti, K. R., Cassavaugh, J. M., Rahim, S., Bulut, G., Zhou, M., Veenstra, T. D., Chen, Q., et al. (2012) · Neoplasia · doi:10.1593/neo.11518 · Cited by 30 · see citing works

Coordinated Regulation of Intracellular Fascin Distribution Governs Tumor Microvesicle Release and Invasive Cell Capacity

Clancy, J. W., Tricarico, C. J., Marous, D. R., & D’Souza‐Schorey, C. (2018) · Molecular and Cellular Biology · doi:10.1128/mcb.00264-18 · Cited by 28 · see citing works

Targeted Therapy in Bone and Soft Tissue Sarcoma in Children and Adolescents

Thompson, P. A., & Chintagumpala, M. (2012) · Current Oncology Reports · doi:10.1007/s11912-012-0223-2 · Cited by 27 · see citing works

MicroRNA-144 inhibits the proliferation, apoptosis, invasion, and migration of osteosarcoma cell line F5M2

Cui, S., & Wang, H. (2015) · Tumor Biology · doi:10.1007/s13277-015-3396-0 · Cited by 27 · see citing works

Ezrin T567 phosphorylation regulates migration and invasion of ectopic endometrial stromal cells by changing actin cytoskeleton

Chen, C., Ye, C., Xia, J., Zhou, Y., & Wu, R. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.117681 · Cited by 27 · see citing works

Primary Bone Tumors: Challenges and Opportunities for CAR-T Therapies

Folkert, I. W., Devalaraja, S., Linette, G. P., WEBER, K. L., & Haldar, M. (2019) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3852 · Cited by 26 · see citing works

Novel CTRP8‐RXFP1‐JAK3‐STAT3 axis promotes Cdc42‐dependent actin remodeling for enhanced filopodia formation and motility in human glioblastoma cells

Głogowska, A., Thanasupawat, T., Beiko, J., Pitz, M. W., Hombach‐Klonisch, S., & Klonisch, T. C. (2021) · Molecular Oncology · doi:10.1002/1878-0261.12981 · Cited by 26 · see citing works

Ezrin regulates inflammation by limiting B cell interleukin-10 production

Pore, D., Matsui, K., Parameswaran, N., & Gupta, N. (2015) · Journal of Immunology · doi:10.4049/jimmunol.1502098 · Cited by 24 · see citing works

Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins

Asp, N., Kvalvaag, A. S., Sandvig, K., & Pust, S. (2016) · Oncotarget · doi:10.18632/oncotarget.8327 · Cited by 26 · see citing works

The clinical significance of the Ezrin gene and circulating tumor cells in osteosarcoma

Zhong, G., Feng, S., Shen, R., Wu, Z., Chen, F., & Zhu, X. (2017) · OncoTargets and Therapy · doi:10.2147/ott.s125589 · Cited by 26 · see citing works

Eight proteins play critical roles in RCC with bone metastasis via mitochondrial dysfunction

Wang, J., Zhao, X., Qi, J., Yang, C., Cheng, H., Ren, Y., & Huang, L. (2015) · Clinical & Experimental Metastasis · doi:10.1007/s10585-015-9731-4 · Cited by 26 · see citing works

Targeted Chemotherapy in Bone and Soft-Tissue Sarcoma

Harwood, J. L., Alexander, J. H., Mayerson, J. L., & Scharschmidt, T. J. (2015) · Orthopedic Clinics of North America · doi:10.1016/j.ocl.2015.06.011 · Cited by 25 · see citing works

Targeting Mechanotransduction in Osteosarcoma: A Comparative Oncology Perspective

Luu, A. K., & Viloria‐Petit, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207595 · Cited by 25 · see citing works

Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma

Paige, M. A., Kosturko, G. W., Bulut, G., Miessau, M., Rahim, S., Toretsky, J. A., Brown, M. L., & Üren, A. (2013) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2013.11.003 · Cited by 25 · see citing works

Ezrin mediates both HGF/Met autocrine and non‐autocrine signaling‐induced metastasis in melanoma

Huang, L., Qin, Y., Zuo, Q., Bhatnagar, K., Xiong, J., Merlino, G. T., & Yu, Y. (2017) · International Journal of Cancer · doi:10.1002/ijc.31196 · Cited by 25 · see citing works

Sequential binding of ezrin and moesin to L-selectin regulates monocyte protrusive behaviour during transendothelial migration

Rey-Gallardo, A., Tomlins, H., Joachim, J., Rahman, I., Kitscha, P., Frudd, K., Parsons, M., & Ívetic, A. (2018) · Journal of Cell Science · doi:10.1242/jcs.215541 · Cited by 25 · see citing works

Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia

da Silva, J. C. L., Coelho‐Silva, J. L., Lima, K., Vicari, H. P., Lazarini, M., Costa-Lotufo, L. V., Traina, F., & Machado‐Neto, J. A. (2021) · Cellular Oncology · doi:10.1007/s13402-021-00621-0 · Cited by 24 · see citing works

Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli

Morales, E. A., Arnaiz, C., Krystofiak, E., Žanić, M., & Tyska, M. J. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110692 · Cited by 24 · see citing works

Caveolin-1 promotes pituitary adenoma cells migration and invasion by regulating the interaction between EGR1 and KLF5

Yang, W., Xu, T., Qiu, P., & Xu, G. (2018) · Experimental Cell Research · doi:10.1016/j.yexcr.2018.01.008 · Cited by 23 · see citing works

Sphingosine 1-phosphate-mediated activation of ezrin-radixin-moesin proteins contributes to cytoskeletal remodeling and changes of membrane properties in epithelial otic vesicle progenitors

Cencetti, F., Bernacchioni, C., Bruno, M., Squecco, R., Idrizaj, E., Berbeglia, M., Bruni, P., & Donati, C. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2018.12.007 · Cited by 23 · see citing works

A streptococcal Fic domain-containing protein disrupts blood-brain barrier integrity by activating moesin in endothelial cells

Ma, Z., Peng, J., Yu, D., Park, J. S., Lin, H., Xu, B., Lu, C., Fan, H., & Waldor, M. K. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1007737 · Cited by 23 · see citing works

Clinical implications of Ezrin and CD44 co-expression in breast cancer

Li-fang, M., & Jiang, T. (2013) · Oncology Reports · doi:10.3892/or.2013.2641 · Cited by 22 · see citing works

Establishment of Four New Human Primary Cell Cultures from Chemo‐Naïve Italian Osteosarcoma Patients

Laschi, M., Bernardini, G., Geminiani, M., Ghezzi, L., Amato, L., Braconi, D., Millucci, L., Frediani, B., Spreafico, A., Franchi, A., et al. (2015) · Journal of Cellular Physiology · doi:10.1002/jcp.24996 · Cited by 22 · see citing works

TGFβ and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells

Leiphrakpam, P. D., Brattain, M. G., Black, J. D., & Wang, J. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra117.001299 · Cited by 22 · see citing works

A Novel Invasive-Related Biomarker in Three Subtypes of Nonfunctioning Pituitary Adenomas

Chen, Y., Chuan, H.-L., Yu, S., Li, C., Wu, Z. B., Li, G., & Zhang, Y. (2017) · World Neurosurgery · doi:10.1016/j.wneu.2017.01.010 · Cited by 21 · see citing works

Inactivation of Src-to-Ezrin Pathway: A Possible Mechanism in the Ouabain-Mediated Inhibition of A549 Cell Migration

Shin, H. K., Ryu, B. J., Choi, S., Kim, S. H., & Lee, K. (2015) · BioMed Research International · doi:10.1155/2015/537136 · Cited by 20 · see citing works

Dynamics of cell rounding during detachment

Nyga, A., Plak, K., Kräter, M., Urbanska, M., Kim, K., Guck, J. R., & Baum, B. (2023) · iScience · doi:10.1016/j.isci.2023.106696 · Cited by 19 · see citing works

Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box

Çelik, H., Hong, S.-H., Colón-López, D. D., Han, J. J., Saygıdeğer, Y., Minas, T. Z., Swift, M. R., Paige, M. A., Glasgow, E. F., Toretsky, J. A., et al. (2015) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-15-0511 · Cited by 20 · see citing works

Sphingosine 1-phosphate activation of ERM contributes to vascular calcification

Morris, T., Borland, S. J., Clarke, C. J., Wilson, C., Hannun, Y. A., Ohanian, V., Canfield, A. E., & Ohanian, J. (2017) · Journal of Lipid Research · doi:10.1194/jlr.m079731 · Cited by 19 · see citing works

Discovery of FERM domain protein–protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer’s disease

Du, Y., Bradshaw, W. J., Leisner, T. M., Annor‐Gyamfi, J. K., Qian, K., Bashore, F. M., Sikdar, A., Nwogbo, F. O., Ivanov, A. A., Frye, S. V., et al. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.105382 · Cited by 18 · see citing works

Identification of key genes as predictive biomarkers for osteosarcoma metastasis using translational bioinformatics

Ding, F.-P., Tian, J., Wu, J., Han, D., & Zhao, D. (2021) · Cancer Cell International · doi:10.1186/s12935-021-02308-w · Cited by 18 · see citing works

Cytoskeletal and Cytoskeleton-Associated Proteins: Key Regulators of Cancer Stem Cell Properties

Li, Y., Wang, D., Ge, H., Güngör, C., Gong, X., & Chen, Y. (2022) · Pharmaceuticals · doi:10.3390/ph15111369 · Cited by 17 · see citing works

Discovery of Biomarkers for Osteosarcoma by Proteomics Approaches

Suehara, Y., Kubota, D., Kikuta, K., Kaneko, K., Kawai, A., & Kondo, T. (2012) · Sarcoma · doi:10.1155/2012/425636 · Cited by 16 · see citing works

Pharmacologic Inhibition of Ezrin-Radixin-Moesin Phosphorylation is a Novel Therapeutic Strategy in Rhabdomyosarcoma

Proudfit, A. M., Bhunia, N., Pore, D., Parker, Y., Lindner, D. J., & Gupta, N. (2020) · Sarcoma · doi:10.1155/2020/9010496 · Cited by 16 · see citing works

Rac1, the actin cytoskeleton and microtubules are key players in clathrin-independent endophilin-A3-mediated endocytosis

Tyckaert, F., Zanin, N., Morsomme, P., & Renard, H. (2022) · Journal of Cell Science · doi:10.1242/jcs.259623 · Cited by 18 · see citing works

Caspase Cleavages of the Lymphocyte-oriented Kinase Prevent Ezrin, Radixin, and Moesin Phosphorylation during Apoptosis

Leroy, C., Belkina, N. V., Long, T., Deruy, E., Dissous, C., Shaw, S., & Tulasne, D. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.721365 · Cited by 16 · see citing works

Disorazoles Block Group A Streptococcal Invasion into Epithelial Cells Via Interference with the Host Factor Ezrin

Rox, K., Rohde, M., Chhatwal, G. S., & Müller, R. (2017) · Cell chemical biology · doi:10.1016/j.chembiol.2016.12.011 · Cited by 15 · see citing works

Osteosarcoma through the Lens of Bone Development, Signaling, and MicroenvironmentPreprint

Young, E. P., Marinoff, A. E., López-Fuentes, E., & Sweet-Cordero, A. (2024) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a041635 · Cited by 14 · see citing works

The clinical significance of changes in ezrin expression in osteosarcoma of children and young adults

Lugowska, I. A., Mierzejewska, E., Lenarcik, M., Klepacka, T., Koch, I., Michalak, E., & Szamotulska, K. (2016) · Tumor Biology · doi:10.1007/s13277-016-5091-1 · Cited by 14 · see citing works

miR‐205‐3p promotes proliferation and reduces apoptosis of breast cancer MCF‐7 cells and is associated with poor prognosis of breast cancer patients

Qiu, C., Huang, F., Zhang, Q. H., Chen, W., & Zhang, H. (2019) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.22966 · Cited by 14 · see citing works

Osteosarcoma-Specific Genes as a Diagnostic Tool and Clinical Predictor of Tumor Progression

Sittiju, P., Chaiyawat, P., Pruksakorn, D., Klangjorhor, J., Wongrin, W., Phinyo, P., Kamolphiwong, R., Phanphaisarn, A., Teeyakasem, P., Kongtawelert, P., et al. (2022) · Biology · doi:10.3390/biology11050698 · Cited by 14 · see citing works

Aggressive nonfunctioning pituitary neuroendocrine tumors

Portovedo, S., Neto, L. V., Soares, P., de Carvalho, D. P., Takiya, C. M., & Miranda‐Alves, L. (2022) · Brain Tumor Pathology · doi:10.1007/s10014-022-00441-6 · Cited by 14 · see citing works

Assessment of signaling pathway inhibitors and identification of predictive biomarkers in malignant pleural mesothelioma

Tranchant, R., Quetel, L., Montagne, F., Wolf, J. D., Meiller, C., de Koning, L., Pimpec‐Barthes, F. L., Zucman‐Rossi, J., Jaurand, M., & Jean, D. (2018) · Lung Cancer · doi:10.1016/j.lungcan.2018.10.015 · Cited by 14 · see citing works

Ezrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma

Penchev, V. R., Chang, Y.-T., Begum, A., Ewachiw, T. E., Gocke, C. B., Li, J. H., McMillan, R. H., Wang, Q., Anders, R. A., Marchionni, L., et al. (2019) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-18-0367 · Cited by 14 · see citing works

Abstract 4505: Development of small molecules to target ezrin as anti-metastatic agents

Bulut, G., Hong, S.-H., Chen, K., Rahim, S., Kosturko, G. W., Beauchamp, E. M., Glasgow, E. F., Toretsky, J. A., Khanna, C., & Üren, A. (2011) · Cancer Research · doi:10.1158/1538-7445.am2011-4505

Abstract 4874: Small molecule inhibitor of ezrin inhibits metastasis in a transgenic mouse model of osteosarcoma

Murdoch, J. T., Hong, S.-H., Bulut, G., Kosturko, G. W., Drebing, L. E., Toretsky, J. A., & Üren, A. (2012) · Cancer Research · doi:10.1158/1538-7445.am2012-4874

Abstract 1550: Small molecule inhibitors of ezrin as anti-metastatic agents in osteosarcoma

Bulut, G., Chen, K., Glasgow, E. F., Hong, S.-H., Lee, H., Kosturko, G. W., Toretsky, J. A., Daar, I. O., Khanna, C., & Üren, A. (2010) · Cancer Research · doi:10.1158/1538-7445.am10-1550

Abstract 2446: Ezrin inhibition up-regulates stress response gene expression and blocks osteosarcoma metastasis

Çelik, H., Bulut, G., Han, J. J., Graham, G. T., Minas, T. Z., Conn, E. J., Hong, S.-H., Pauly, G. T., Hayran, M., Li, X., et al. (2016) · Cancer Research · doi:10.1158/1538-7445.am2016-2446

Abstract 3987: Evaluation of anti–malarial compounds as inhibitors of ezrin in osteosarcoma cells

Çelik, H., Kallarakal, A. T., Colón-López, D. D., Toretsky, J. A., Bosch, J., & Üren, A. (2014) · Cancer Research · doi:10.1158/1538-7445.am2014-3987