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Angiotensin Inhibition, TGF-β and EMT in Cancer

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Epigenetic regulation of hybrid epithelial-mesenchymal cell states in cancer

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Functional Hierarchy and Cooperation of EMT Master Transcription Factors in Breast Cancer Metastasis

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RNA binding protein RBMS3 is a common EMT effector that modulates triple-negative breast cancer progression via stabilizing PRRX1 mRNA

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The ZEB2‐dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer

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E2A Modulates Stemness, Metastasis, and Therapeutic Resistance of Breast Cancer

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Targeting CSC-related transcription factors by E3 ubiquitin ligases for cancer therapy

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CD95/Fas and metastatic disease: What does not kill you makes you stronger

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Targeting key proteins involved in transcriptional regulation for cancer therapy: Current strategies and future prospective

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Transforming growth factor-β in tumour development

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Patients with mesenchymal tumours and high Fusobacteriales prevalence have worse prognosis in colorectal cancer (CRC)

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c‐Myb promotes growth and metastasis of colorectal cancer through c‐fos‐induced epithelial‐mesenchymal transition

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NR2F2 controls malignant squamous cell carcinoma state by promoting stemness and invasion and repressing differentiation

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Phenotypic Plasticity of Cancer Cells Based on Remodeling of the Actin Cytoskeleton and Adhesive Structures

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Therapeutic potentials of medicinal plants and significance of computational tools in anti-cancer drug discovery

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Dual roles of chromatin remodeling protein BRG1 in angiotensin II-induced endothelial–mesenchymal transition

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Tackle Epithelial-Mesenchymal Transition With Epigenetic Drugs in Cancer

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Canonical TGFβ signaling induces collective invasion in colorectal carcinogenesis through a Snail1- and Zeb1-independent partial EMT

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Multifaceted roles of CCL20 (C-C motif chemokine ligand 20): mechanisms and communication networks in breast cancer progression

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The role of the ZEB1–neuroinflammation axis in CNS disorders

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Breast cancer metastasis to bone: From epithelial to mesenchymal transition to breast osteoblast-like cells

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The epithelial–mesenchymal transition regulators Twist, Slug, and Snail are associated with aggressive tumour features and poor outcome in prostate cancer patients

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Epithelial-to-Mesenchymal Transition-Derived Heterogeneity in Head and Neck Squamous Cell Carcinomas

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Plasticity in cell migration modes across development, physiology, and disease

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Transcriptional and post-transcriptional control of epithelial-mesenchymal plasticity: why so many regulators?

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Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1

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Harnessing function of EMT in hepatocellular carcinoma: From biological view to nanotechnological standpoint

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In vitro Studies of Transendothelial Migration for Biological and Drug Discovery

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The Molecular Mechanism of Epithelial–Mesenchymal Transition for Breast Carcinogenesis

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Mutual regulation of TGFβ-induced oncogenic EMT, cell cycle progression and the DDR

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PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1

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Resveratrol and Its Analogs: Potent Agents to Reverse Epithelial-to-Mesenchymal Transition in Tumors

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The Autophagic Route of E-Cadherin and Cell Adhesion Molecules in Cancer Progression

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The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma

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Born to Run? Diverse Modes of Epithelial Migration

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FSH induces EMT in ovarian cancer via ALKBH5-regulated Snail m6A demethylation

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Chemoresistance in Ovarian Cancer: Prospects for New Drugs

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Cancer progression as a learning process

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Epithelial-Mesenchymal Transition-Related MicroRNAs and Their Target Genes in Colorectal Cancerogenesis

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Intrinsic Balance between ZEB Family Members Is Important for Melanocyte Homeostasis and Melanoma Progression

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Different signaling and functionality of Rac1 and Rac1b in the progression of lung adenocarcinoma

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Exosomal microRNAs in colorectal cancer: Overcoming barriers of the metastatic cascade (Review)

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An Orthotopic Patient-Derived Xenograft (PDX) Model Allows the Analysis of Metastasis-Associated Features in Colorectal Cancer

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ERK inactivation enhances stemness of NSCLC cells via promoting Slug-mediated epithelial-to-mesenchymal transition

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“In medio stat virtus”: Insights into hybrid E/M phenotype attitudes

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ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer

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EMT signaling: potential contribution of CRISPR/Cas gene editing

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Mesenchymal-epithelial transition regulates initiation of pluripotency exit before gastrulation

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Sirtuins’ Deregulation in Bladder Cancer: SIRT7 Is Implicated in Tumor Progression through Epithelial to Mesenchymal Transition Promotion

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Transcriptional activators YAP/TAZ and AXL orchestrate dedifferentiation, cell fate, and metastasis in human osteosarcoma

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Ellagitannins, promising pharmacological agents for the treatment of cancer stem cells

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EGFR is a pivotal player of the E2/ERβ – mediated functional properties, aggressiveness, and stemness in triple‐negative breast cancer cells

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Pleomorphic Adenoma of the Salivary Glands and Epithelial–Mesenchymal Transition

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TRAIL receptor-induced features of epithelial-to-mesenchymal transition increase tumour phenotypic heterogeneity: potential cell survival mechanisms

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The Role of Calcium Signaling in Regulation of Epithelial-Mesenchymal Transition

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Foretinib induces G2/M cell cycle arrest, apoptosis, and invasion in human glioblastoma cells through c-MET inhibition

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Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition

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CTCF Expression and Dynamic Motif Accessibility Modulates Epithelial–Mesenchymal Gene Expression

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m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial–mesenchymal transition of lung cancer cells

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Short and dysfunctional telomeres sensitize the kidneys to develop fibrosis

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Modulation of E-Cadherin and N-Cadherin by ovarian steroids and embryonic stimuli

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Essential role of aerobic glycolysis in epithelial-to-mesenchymal transition during carcinogenesis

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LINC00261 Is Differentially Expressed in Pancreatic Cancer Subtypes and Regulates a Pro-Epithelial Cell Identity

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An epithelial-to-mesenchymal transition induced extracellular vesicle prognostic signature in non-small cell lung cancer

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Non-canonical functions of SNAIL drive context-specific cancer progression

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Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions

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The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus

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FGF4 Promotes Skin Wound Repair through p38 MAPK and GSK3β-Mediated Stabilization of Slug

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Dynamics of epithelial–mesenchymal plasticity driving cancer drug resistance

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Baicalin alleviates adriamycin-induced focal segmental glomerulosclerosis and proteinuria by inhibiting the Notch1-Snail axis mediated podocyte EMT

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Epithelial-to-mesenchymal transition is a resistance mechanism to sequential MET-TKI treatment of MET-amplified EGFR-TKI resistant non-small cell lung cancer cells

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Defining epithelial-mesenchymal transitions in animal development

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Epithelial-to-Mesenchymal Plasticity in Circulating Tumor Cell Lines Sequentially Derived from a Patient with Colorectal Cancer

Balçık-Erçin, P., Cayrefourcq, L., Soundararajan, R., Mani, S. A., & Alix‐Panabières, C. (2021) · Cancers · doi:10.3390/cancers13215408 · Cited by 26

A stroma-corrected ZEB1 transcriptional signature is inversely associated with antitumor immune activity in breast cancer

Block, C. J., Dyson, G. E., Campeanu, I. J., Watza, D., Ratnam, M., & Wu, G. (2019) · Scientific Reports · doi:10.1038/s41598-019-54282-z · Cited by 25

Silencing of RAD51AP1 suppresses epithelial–mesenchymal transition and metastasis in non‐small cell lung cancer

Wu, Y., Wang, H.-F., Qiao, L., Jin, X., Dong, H., & Wang, Y. (2019) · Thoracic Cancer · doi:10.1111/1759-7714.13124 · Cited by 25

Deregulation of Transcription Factor Networks Driving Cell Plasticity and Metastasis in Pancreatic Cancer

van Roey, R., Brabletz, T., Stemmler, M. P., & Armstark, I. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.753456 · Cited by 26

A specialist-generalist framework for epithelial-mesenchymal plasticity in cancer

Cook, D. P., & Wrana, J. L. (2022) · Trends in cancer · doi:10.1016/j.trecan.2022.01.014 · Cited by 23

Mesenchymal–epithelial transition in lymph node metastases of oral squamous cell carcinoma is accompanied by ZEB1 expression

Horny, K., Sproll, C. K., Peiffer, L., Furtmann, F., Gerhardt, P., Gravemeyer, J., Stoecklein, N. H., Spassova, I., & Becker, J. C. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04102-w · Cited by 25

E-box binding transcription factors in cancer

Pan, Y., van der Watt, P. J., & Kay, S. A. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1223208 · Cited by 24

DLAT activates EMT to promote HCC metastasis by regulating GLUT1-mediated aerobic glycolysis

Yin, Q., Yao, Y., Ni, J., Zhang, Y., Wu, J., Zeng, H., Wu, W., Zhuo, W., Ying, J., & Li, J. (2025) · Molecular Medicine · doi:10.1186/s10020-025-01125-5 · Cited by 26

Xenopus, an emerging model for studying pathologies of the neural crest

Medina-Cuadra, L., & Monsoro-Burq, A. H. (2021) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2021.03.002 · Cited by 24

Heterogeneous Circulating Tumor Cells in Sarcoma: Implication for Clinical Practice

Agnoletto, C., Caruso, C., & Garofalo, C. (2021) · Cancers · doi:10.3390/cancers13092189 · Cited by 27

TGFβ‐induced FOXS1 controls epithelial–mesenchymal transition and predicts a poor prognosis in liver cancer

Bévant, K., Desoteux, M., Angenard, G., Pineau, R., Caruso, S., Louis, C., Papoutsoglou, P., Sulpice, L., Gilot, D., Zucman‐Rossi, J., et al. (2021) · Hepatology Communications · doi:10.1002/hep4.1866 · Cited by 26

Proteoglycans Determine the Dynamic Landscape of EMT and Cancer Cell Stemness

Karagiorgou, Z., Fountas, P. N., Manou, D., Knutsen, E., & Theocharis, A. D. (2022) · Cancers · doi:10.3390/cancers14215328 · Cited by 24

Vimentin epigenetic deregulation in Bladder Cancer associates with acquisition of invasive and metastatic phenotype through epithelial-to-mesenchymal transition

Monteiro‐Reis, S., Miranda‐Gonçalves, V., Guimarães‐Teixeira, C., Martins‐Lima, C., Lobo, J., Montezuma, D., Dias, P. C., Neyret‐Kahn, H., Bernard‐Pierrot, I., Henrique, R., et al. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.77181 · Cited by 24

A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling

Zhu, L., Tang, Y., Li, X., Kerk, S. A., Lyssiotis, C. A., Feng, W., Sun, X., Hespe, G. E., Wang, Z., Stemmler, M. P., et al. (2023) · The EMBO Journal · doi:10.15252/embj.2022111148 · Cited by 25

Upregulation of LINC00501 by H3K27 acetylation facilitates gastric cancer metastasis through activating epithelial‐mesenchymal transition and angiogenesis

Dou, R., Han, L., Yang, C., Fang, Y., Zheng, J., Liang, C., Song, J., Chen, W., Huang, G., Zhong, P., et al. (2023) · Clinical and Translational Medicine · doi:10.1002/ctm2.1432 · Cited by 24

miR-204/COX5A axis contributes to invasion and chemotherapy resistance in estrogen receptor-positive breast cancers

Zeng, J., Li, G., Xia, Y., Wang, F., Wang, Y., Xu, S., Zhou, Y., Liu, X., Xie, X., & Zhang, J. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.07.027 · Cited by 24

Epithelial–Mesenchymal Transition in the Resistance to Somatostatin Receptor Ligands in Acromegaly

Gil, J., Jordà, M., Soldevila, B., & Puig‐Domingo, M. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.646210 · Cited by 23

Dual role of Snail1 as transcriptional repressor and activator

de Herreros, A. G. (2023) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2023.189037 · Cited by 23

Melatonin and Its Role in the Epithelial-to-Mesenchymal Transition (EMT) in Cancer

Martínez‐Campa, C., Garcia, V. A., Alonso‐González, C., González, A., & Cos, S. (2024) · Cancers · doi:10.3390/cancers16050956 · Cited by 24

ZNF451 stabilizes TWIST2 through SUMOylation and promotes epithelial-mesenchymal transition.

Wang, Z., Gu, S., Yu, Y., Feng, Y.-L., Xiao, M., & Feng, X. (2021) · PubMed Central · Cited by 22

Single-cell resolution of MET- and EMT-like programs in osteoblasts during zebrafish fin regeneration

Tang, W., Watson, C. J., Olmstead, T., Allan, C. H., & Kwon, R. Y. (2022) · iScience · doi:10.1016/j.isci.2022.103784 · Cited by 27

Epithelial-to-Mesenchymal Transition-Related Markers in Prostate Cancer: From Bench to Bedside

Gogola, S., Rejzer, M., Bahmad, H. F., Abou-Kheir, W. G., Omarzai, Y., & Poppiti, R. (2023) · Cancers · doi:10.3390/cancers15082309 · Cited by 22

Mesenchymal–epithelial transition and AXL inhibitor TP-0903 sensitise triple-negative breast cancer cells to the antimalarial compound, artesunate

Terragno, M., Vetrova, A., Semenov, O., Sayan, E., Kriajevska, M. V., & Tulchinsky, E. M. (2024) · Scientific Reports · doi:10.1038/s41598-023-50710-3 · Cited by 22

EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET

Goossens, S., Vandamme, N., Vlierberghe, P. V., & Berx, G. (2017) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2017.06.006 · Cited by 292

Understanding the Complex Milieu of Epithelial-Mesenchymal Transition in Cancer Metastasis: New Insight Into the Roles of Transcription Factors

Imodoye, S. O., Adedokun, K. A., Muhammed, A. O., Bello, I. O., Muhibi, M. A., Oduola, T., & Oyenike, M. A. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.762817 · Cited by 50

Epithelial–mesenchymal transition and its transcription factors

Debnath, P., Huirem, R. S., Dutta, P., & Palchaudhuri, S. (2021) · Bioscience Reports · doi:10.1042/bsr20211754 · Cited by 307

Epithelial mesenchymal transition Transcription Factor (TF): The structure, function and microRNA feedback loop

Alidadiani, N., Ghaderi, S., Dilaver, N., Bakhshamin, S., & Bayat, M. (2018) · Gene · doi:10.1016/j.gene.2018.06.049 · Cited by 39

Role of E2Fs and mitotic regulators controlled by E2Fs in the epithelial to mesenchymal transition

Jusino, S., & Saavedra, H. I. (2019) · Experimental Biology and Medicine · doi:10.1177/1535370219881360 · Cited by 21