The DOI matches its Crossref record; 174 of the 174 references it cites were found in a registry or an index.
Non-redundant functions of EMT transcription factors
Abstract
Epithelial-mesenchymal transition (EMT) is a crucial embryonic programme that is executed by various EMT transcription factors (EMT-TFs) and is aberrantly activated in cancer and other diseases. However, the causal role of EMT and EMT-TFs in different disease processes, especially cancer and metastasis, continues to be debated. In this Review, we identify and describe specific, non-redundant functions of the different EMT-TFs and discuss the reasons that may underlie disputes about EMT in cancer.
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“Previously, ZEB1 was shown to play a critical role in epithelial-mesenchymal transition in neural crest migration and glioblastoma83,84”
From Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer’s disease-specific cis-regulatory elements (2023) · cites this paper as [84]
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Additional file 1 of EMP3 as a prognostic biomarker correlates with EMT in GBM
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Additional file 3 of EMP3 as a prognostic biomarker correlates with EMT in GBM
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Additional file 2 of EMP3 as a prognostic biomarker correlates with EMT in GBM
Li, L., Xia, S., Zhao, Z., Deng, L., Wang, H., Yang, D., Hu, Y., Ji, J., Huang, D., & Xin, T. (2024) · Figshare · doi:10.6084/m9.figshare.26668509
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Metadata
- Authors
- Stemmler, M. P., Eccles, R. L., Brabletz, S., & Brabletz, T.
- Affiliations
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Corresponding author
- Brabletz, Thomas
- Venue
- Nature Cell Biology
- Published
- 2019-01
- Volume
- 21
- Issue
- 1
- Pages
- 102-112
- ISSN
- 1465-7392 (ISSN-L)
- 1476-4679
- OpenAlex
- W2898606030
- Cited by
- 524
- References
- 174
- Citations by year
- 2026: 31 · 2025: 46 · 2024: 79 · 2023: 69 · 2022: 79 · 2021: 107 · 2020: 79 · 2019: 34
- FWCI
- 5.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Cell Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Cancer Cells and Metastasis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › TGF-β signaling in diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- epithelial-mesenchymal transition, EMT transcription factors, non-redundant function, cancer, metastasis, embryonic development, transcriptional regulation
- MeSH terms
- Animals, Humans, Models, Genetic, Neoplasms, Transcription Factors, Gene Expression Regulation, Neoplastic, Gene Expression Profiling, Embryonic Development, Epithelial-Mesenchymal Transition
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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