The DOI matches its Crossref record; 246 of the 248 references it cites were found in a registry or an index.
Adipogenesis and metabolic health
Abstract
Obesity is characterized by increased adipose tissue mass and has been associated with a strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public health issue of major proportion. The expansion of adipose depots can be driven either by the increase in adipocyte size (hypertrophy) or by the formation of new adipocytes from precursor differentiation in the process of adipogenesis (hyperplasia). Notably, adipocyte expansion through adipogenesis can offset the negative metabolic effects of obesity, and the mechanisms and regulators of this adaptive process are now emerging. Over the past several years, we have learned a considerable amount about how adipocyte fate is determined and how adipogenesis is regulated by signalling and systemic factors. We have also gained appreciation that the adipogenic niche can influence tissue adipogenic capability. Approaches aimed at increasing adipogenesis over adipocyte hypertrophy can now be explored as a means to treat metabolic diseases.
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“A key outcome of muscle–adipose crosstalk is the promotion of metabolic flexibility”
From Exercise-Induced Muscle–Fat Crosstalk: Molecular Mediators and Their Pharmacological Modulation for the Maintenance of Metabolic Flexibility in Aging (2025) · cites this paper as [89]
In the citing paper
“The expansion of adipose depots can be driven either by the increase in adipocyte size (hypertrophy), or by the formation of new adipocytes from perivascular preadipocytes and pericytes (hyperplasia).[ 23 ]”
From Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review (2022) · cites this paper as [23]
In the citing paper
“During transient hyperlipidaemia after food intake, adipose tissues are driven to expand.”
From Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review (2022) · cites this paper as [23]
In the citing paper
“Thus, even before obesity becomes obvious, persistent hyperlipidaemia contributes to fat redistribution, for example, subcutaneous adipose inflammation and lipolysis, fuelling visceral adipose tissue (VAT) expansion.[ 23 ]”
From Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review (2022) · cites this paper as [23]
In the citing paper
“Chronic inflammation in extant adipose depots and other tissues also contribute to the pathophysiology of adipose tissue dysfunction, including the gradual impairment of adipogenesis that contributes to IR and metabolic disease.[ 23 ]”
From Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review (2022) · cites this paper as [23]
In the citing paper
“But after a long period of systemic inflammaging, chronic inflammation in adipose depots would lead to the systemic atrophy and wasting observed in cachexia and full‐blown sarcopenia.[ 23 ]”
From Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review (2022) · cites this paper as [23]
In the citing paper
“In fact, AT is remarkably capable of expanding to more than double its original size by hypertrophy (enlargement of the cell size) and/or hyperplasia (increase in cell number) [3].”
From Adipose Tissue: A Novel Target of the Incretin Axis? A Paradigm Shift in Obesity-Linked Insulin Resistance (2024) · cites this paper as [3]
Citations
Cites
Positional cloning of the mouse obese gene and its human homologue
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419
Obesity is associated with macrophage accumulation in adipose tissue
Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041
The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function
Goossens, G. H. (2017) · Obesity Facts · doi:10.1159/000471488 · Cited by 8,481
Increased oxidative stress in obesity and its impact on metabolic syndrome
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508
Mechanisms of fatty acid-induced inhibition of glucose uptake.
Boden, G., Chen, X., Ruiz, J., White, J. V., & Rossetti, L. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117252 · Cited by 3,720
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Baker, D. J., Wijshake, T., Tchkonia, T., LeBrasseur, N. K., Childs, B. G., van de Sluis, B., Kirkland, J. L., & van Deursen, J. M. (2011) · Nature · doi:10.1038/nature10600 · Cited by 3,670
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
Tontonoz, P., Hu, E., & Spiegelman, B. M. (1994) · Cell · doi:10.1016/0092-8674(94)90006-x · Cited by 3,564
A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes
Scherer, P. E., Williams, S. P., Fogliano, M., Baldini, G., & Lodish, H. F. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.45.26746 · Cited by 3,238
Self-citationKim, H. J., Park, S. Y., Choi, Y. J., Han, S. J., Lee, K. W., & Kim, D. J. (2013) · Hormone Research in Paediatrics · doi:10.1159/000348848 · Cited by 3,061
Fetal and infant growth and impaired glucose tolerance at age 64
Hales, C. N., Barker, D. J., Clark, P. M., Cox, L. J., Fall, C., Osmond, C., & Winter, P. D. (1991) · BMJ · doi:10.1136/bmj.303.6809.1019 · Cited by 2,708
Cited by
Sorted by citations
Items 401–500 of 999
Qiu, S., Cho, J. S., Kim, J. T., Moon, J. H., Zhou, Y., Lee, S. B., Park, H. J., & Lee, H. J. (2021) · Phytomedicine · doi:10.1016/j.phymed.2021.153715 · Cited by 20
The miR-23–27–24 cluster: an emerging target in NAFLD pathogenesis
Ru, L., Wang, X.-M., & Niu, J.-Q. (2022) · Acta Pharmacologica Sinica · doi:10.1038/s41401-021-00819-w · Cited by 21
Luca, T., Pezzino, S., Puleo, S., & Castorina, S. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05547-3 · Cited by 19
GSK3β Deficiency Expands Obese Adipose Vasculature to Mitigate Metabolic Disorders
Wang, L., Li, J., Tang, P., Zhu, D., Tai, L., Wang, Y., Miyata, T., Woodgett, J. R., & Di, L. (2024) · Circulation Research · doi:10.1161/circresaha.124.325187 · Cited by 21
Lin, Y., Pan, Y., Jiang, T., Chen, Y., Shang, T., Xu, M., Feng, H.-B., Ma, Y., Tan, Y., Wang, H., et al. (2025) · Journal of Biomedical Science · doi:10.1186/s12929-025-01124-y · Cited by 21
Identification of SCARA3 with potential roles in metabolic disorders
Peng, H., Guo, Q., Su, T., Xiao, Y., Li, C., Huang, Y., & Luo, X. (2020) · Aging · doi:10.18632/aging.202228 · Cited by 19
Roflumilast Suppresses Adipogenic Differentiation via AMPK Mediated Pathway
Xu, W., Zhang, J., & Xiao, J. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.662451 · Cited by 19
Al-Baiaty, F. D. R., Ismail, A., Latiff, Z. A., Nawawi, K. N. M., Ali, R. A. R., & Mokhtar, N. M. (2021) · Frontiers in Pediatrics · doi:10.3389/fped.2021.667247 · Cited by 26
Fibrillin-1 regulates white adipose tissue development, homeostasis, and function
Muthu, M. L., Tiedemann, K., Fradette, J., Komarova, S. V., & Reinhardt, D. P. (2022) · Matrix Biology · doi:10.1016/j.matbio.2022.05.002 · Cited by 19
Nakayama, M., Okada, H., Seki, M., Suzuki, Y., Chung, U., Ohba, S., & Hojo, H. (2022) · Regenerative Therapy · doi:10.1016/j.reth.2022.05.001 · Cited by 15
Cho, H.-H., Jang, S.-H., Won, C., Kim, C.-H., Kim, H.-D., Kim, T. H., & Cho, J. (2022) · Molecules · doi:10.3390/molecules27134232 · Cited by 19
Li, D., Xu, Z., Li, Y., Gan, L., Wu, P., Wu, R., Jin, J., Zheng, X., Zhang, K., Ma, H., et al. (2022) · Food & Function · doi:10.1039/d2fo00337f · Cited by 21
The neutral amino acid transporter SLC7A10 in adipose tissue, obesity and insulin resistance
Jersin, R. Å., Jonassen, L. R., & Dankel, S. N. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.974338 · Cited by 19
Zhang, Z., Jiang, Y., Su, L., Ludwig, S. M., Zhang, X., Tang, M., Li, X., Anderton, P. D., Zhan, X., Choi, M., et al. (2022) · Cell Metabolism · doi:10.1016/j.cmet.2022.09.018 · Cited by 18
Single-cell analysis of white adipose tissue reveals the tumor-promoting adipocyte subtypes
Liu, S.-Q., Chen, D.-Y., Li, B., Gao, Z., Feng, H.-F., Yu, X., Liu, Z., Wang, Y., Li, W., Sun, S., et al. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04256-7 · Cited by 21
Huang, C., Luo, Y., Zeng, B., Chen, Y., Liu, Y., Chen, W., Liao, X., Liu, Y., Wang, Y., & Wang, X. (2023) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2023.109437 · Cited by 21
Han, S. M., Park, E. S., Park, J., Nahmgoong, H., Choi, Y. H., Oh, J., Yim, K. M., Lee, W. T., Lee, Y. K., Jeon, Y. G., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-44181-3 · Cited by 23
PAQR4 regulates adipocyte function and systemic metabolic health by mediating ceramide levels
Zhu, Q., Chen, S., Funcke, J., Straub, L. G., Lin, Q., Zhao, S., Joung, C., Zhang, Z., Kim, D.-S., Li, N., et al. (2024) · Nature Metabolism · doi:10.1038/s42255-024-01078-9 · Cited by 20
Self-citationWang, X., Zhao, Y., Zhou, D., Tian, Y., Feng, G., & Lu, Z. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-03519-9 · Cited by 19
Annexin A1 binds PDZ and LIM domain 7 to inhibit adipogenesis and prevent obesity
Fang, L., Liu, C., Jiang, Z., Wang, M., Geng, K., Xu, Y., Zhu, Y., Fu, Y., Xue, J., Shan, W., et al. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01930-0 · Cited by 20
Barilla, S., Liang, N., Mileti, E., Ballaire, R., Lhomme, M., Ponnaiah, M., Lemoine, S., Soprani, A., Gautier, J., Amri, E., et al. (2020) · Molecular Metabolism · doi:10.1016/j.molmet.2020.101066 · Cited by 19
Li, N., Chen, K., Dong, H., Yang, J., Yoshizawa, M., Kagami, H., & Li, X. (2021) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2021.9995 · Cited by 21
RETRACTED: HOXA5-miR-574-5p axis promotes adipogenesis and alleviates insulin resistance
Li, Y., Li, J., Yu, H., Liu, Y., Song, H., Tian, X., Liu, D., Yan, C., & Han, Y. (2021) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2021.08.031 · Cited by 18
RetractedMirzaeicheshmeh, E., Zerrweck, C., Centeno-Cruz, F., Baca, P., Martínez-Hernández, A. G., Garcia‐Ortíz, H., Contreras-Cubas, C., Salas-Martínez, M. G., Saldaña‐Alvarez, Y., Mendoza‐Caamal, E., et al. (2021) · Adipocyte · doi:10.1080/21623945.2021.1978157 · Cited by 18
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González-Casanova, J. E., Durán‐Agüero, S., Fuentes, N. C., Gamboa-Arancibia, M. E., Bruna, T., Bermúdez, V., & Rojas-Gómez, D. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222212145 · Cited by 20
Ahmed, H. H., Kotob, S. E., Abdrabou, A., Aglan, H. A., & Elmegeed, G. A. (2021) · Biomedical & Pharmacology Journal · doi:10.13005/bpj/2274 · Cited by 18
Perna, A., Carleo, M. A., Mascolo, S., Guida, A., Contieri, M., Sellitto, C., Hay, E., Blasiis, P. D., Lucariello, A., Guerra, G., et al. (2022) · AIDS · doi:10.1097/qad.0000000000003455 · Cited by 18
Aragón‐Vela, J., Carrillo, J. A.-B., Moreno-Racero, A., & Plaza‐Díaz, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232315413 · Cited by 19
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Ye, J., Gao, C. D., Liang, Y., Hou, Z., Shi, Y., & Wang, Y. (2023) · Cell Regeneration · doi:10.1186/s13619-023-00157-8 · Cited by 19
Wang, B., & Du, . (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2023.2227258 · Cited by 20
Cardiac-to-adipose axis in metabolic homeostasis and diseases: special instructions from the heart
Tang, S., Li, R., Ma, W., Liu, L., Gao, J., Cao, Y., & Gan, L. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01097-1 · Cited by 20
SIRT6’s function in controlling the metabolism of lipids and glucose in diabetic nephropathy
Wang, Y., Liu, T., Cai, Y., Liu, W., & Guo, J. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1244705 · Cited by 19
Fibroblasts in immune-mediated inflammatory diseases: The soil of inflammation
Zhou, Y., Cao, T., Li, Z., Qiao, H., Dang, E., Shao, S., & Wang, G. (2023) · Clinical Immunology · doi:10.1016/j.clim.2023.109849 · Cited by 19
Revisiting the beyond BMI paradigm in excess weight diagnosis and management: A call to action
Aguas‐Ayesa, M., Yárnoz‐Esquíroz, P., Perdomo, C. M., Olazarán, L., Vegas-Aguilar, I. M., García‐Almeida, J. M., Gómez‐Ambrosi, J., & Frühbeck, G. (2024) · European Journal of Clinical Investigation · doi:10.1111/eci.14218 · Cited by 17
Acute Aerobic Exercise Remodels the Adipose Tissue Progenitor Cell Phenotype in Obese Adults
Ludzki, A. C., Krueger, E. M., Baldwin, T. C., Schleh, M. W., Porsche, C. E., Ryan, B. J., Muir, L. A., Singer, K., Lumeng, C. N.-K., & Horowitz, J. F. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00903 · Cited by 17
Novel antiadipogenic effect of menadione in 3T3-L1 cells
Funk, M. I., Conde, M. A., Piwien‐Pilipuk, G., & Uranga, R. M. (2021) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2021.109491 · Cited by 18
Transcriptional and epigenetic control of adipocyte remodeling during obesity
Barilla, S., Treuter, E., & Venteclef, N. (2021) · Obesity · doi:10.1002/oby.23248 · Cited by 20
Kaartinen, M. T., Hang, A., Barry, A., Arora, M., Heinonen, S., Lundbom, J., Hakkarainen, A., Lundholm, N., Rissanen, A., Kaprio, J. A., et al. (2022) · Matrix Biology · doi:10.1016/j.matbio.2022.02.005 · Cited by 19
Lymperopoulos, A., Altsman, V. L., & Stoicovy, R. A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157239 · Cited by 24
Circulating miR-216a as a biomarker of metabolic alterations and obesity in women
Vonhögen, I. G. C., Mohseni, Z., Winkens, B., Xiao, K., Thum, T., Calore, M., Martins, P. A. D. C., Windt, L. J. D., Spaanderman, M. E. A., & Ghossein‐Doha, C. (2020) · Non-coding RNA Research · doi:10.1016/j.ncrna.2020.08.001 · Cited by 17
Donepudi, A. C., Lee, Y., Lee, J., Schuetz, J. D., & Manautou, J. E. (2021) · The FASEB Journal · doi:10.1096/fj.202001299rr · Cited by 17
Neuroimmune regulation of white adipose tissues
Qian, X., Meng, X., Zhang, S., & Zeng, W. (2021) · FEBS Journal · doi:10.1111/febs.16213 · Cited by 17
Molonia, M. S., Quesada‐López, T., Speciale, A., Muscarà, C., Saija, A., Villarroya, F., & Cimino, F. (2021) · Chemistry & Biodiversity · doi:10.1002/cbdv.202100607 · Cited by 17
The role of bone marrow adipocytes in cancer progression: the impact of obesity
Hernandez, M., Shin, S., Muller, C., & Attané, C. (2022) · Cancer and Metastasis Reviews · doi:10.1007/s10555-022-10042-6 · Cited by 17
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Chen, Y.-Q., Li, Q.-W., Liu, Y.-T., Chen, X., Jiang, S., Lin, W.-M., Zhang, Y.-N., Liu, R., Shao, B., Chen, C., et al. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010425 · Cited by 14
Wang, J., Zhang, Z., Yan, L., Chen, J., Wang, F., Wang, L., Liu, J., & Zhang, X. (2023) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202200478 · Cited by 18
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Li, Y., Feng, G., Liu, J., Yang, T., Hou, R., Liu, J., & Wang, X. (2023) · Macromolecular Chemistry and Physics · doi:10.1002/macp.202300257 · Cited by 17
Liu, L., Lin, J., Yin, M., Liu, L., Gao, J., Liu, X., Zhu, J., & Wu, A. (2024) · Scientific Reports · doi:10.1038/s41598-024-57388-1 · Cited by 17
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Wu, Y., Sun, Y., Song, Y., Wang, J., Han, Y., Yang, N., Lin, H. H., Yin, Y., & Han, X. (2024) · Cell Death and Differentiation · doi:10.1038/s41418-024-01309-2 · Cited by 18
Li, X.-F., Zhao, D., & Wang, H. (2024) · BMC Public Health · doi:10.1186/s12889-024-19576-6 · Cited by 20
Zhou, X., Shi, X., Wang, J., Zhang, X., Xu, Y., Liu, Y., Li, X., & Yang, G. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29652 · Cited by 16
Triptolide enhances lipolysis of adipocytes by enhancing ATGL transcription via upregulation of p53
Wang, X., Xu, M., Peng, Y., Qimuge, N., Xu, Y., Wang, X., Yang, G., Shi, X., & Li, X. (2020) · Phytotherapy Research · doi:10.1002/ptr.6779 · Cited by 17
Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation
Jin, Y., Ji, Y., Song, Y., Choe, S. S., Jeon, Y. G., Na, H., Nam, T. W., Kim, H. J., Nahmgoong, H., Kim, S. M., et al. (2020) · Diabetes · doi:10.2337/db19-1239 · Cited by 15
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De Fano, M., Malara, M., Vermigli, C., & Murdolo, G. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25168650 · Cited by 17
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Ling, M., Lai, X., Quan, L., Li, F., Lang, L., Fu, Y., Feng, S., Yi, X., Zhu, C., Gao, P., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147524 · Cited by 16
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Abudujilile, D., Wang, W., Aimaier, A., Chang, L., Dong, Y., Wang, Y., Fan, X., Ma, Y., Wang, Y., Ziyayiding, D., et al. (2022) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-022-03743-6 · Cited by 17
Pan, J., Yin, J., Gan, L., & Xue, J. (2022) · Obesity Reviews · doi:10.1111/obr.13521 · Cited by 21
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Goel, A., Yamini, Y., Gusain, C., Sharma, B., Purohit, R., Das, P., & Padwad, Y. S. (2023) · Chemistry - An Asian Journal · doi:10.1002/asia.202300179 · Cited by 16
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Xiong, S., Yu, S., Wang, K., Xiong, X., Xia, M., Zeng, G., & Huang, Q. (2023) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202200763 · Cited by 17
Saad, B. (2023) · Biomedicines · doi:10.3390/biomedicines11082204 · Cited by 16
The role of Sirtuin 2 in liver - An extensive and complex biological process
Li, S., & Guo, L. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122431 · Cited by 18
Liu, X.-R., Yang, J., Yan, Y., Li, Q.-F., & Huang, R.-L. (2024) · Theranostics · doi:10.7150/thno.93919 · Cited by 13
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Xining, Z., & Luo, S. (2024) · Cell Transplantation · doi:10.1177/09636897241264976 · Cited by 18
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Igata, M., Islam, M. A., Tada, A., Takagi, M., Kober, A. K. M. H., Albarracín, L., Aso, H., Ikeda‐Ohtsubo, W., Miyazawa, K., Yoda, K., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01180 · Cited by 16
Fasting-mediated metabolic and toxicity reprogramming impacts circulating microRNA levels in humans
Ravanidis, S., Grundler, F., de Toledo, F. W., Dimitriou, E., Tekos, F., Skaperda, Z., Kouretas, D., & Doxakis, E. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112187 · Cited by 17
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Hatzmann, F. M., Großmann, S., Waldegger, P., Wiegers, G. J., Mandl, M., Rauchenwald, T., Pierer, G., & Zwerschke, W. (2022) · Adipocyte · doi:10.1080/21623945.2022.2129060 · Cited by 16
Behan-Bush, R. M., Liszewski, J. N., Schrodt, M. V., Vats, B., Li, X., Lehmler, H., Klingelhutz, A. J., & Ankrum, J. A. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.2c07281 · Cited by 18
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Santopaolo, M., Gu, Y., Spinetti, G., & Madeddu, P. R. (2020) · Clinical Science · doi:10.1042/cs20200220 · Cited by 16
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Dutta, A. B., Lank, D. S., Przanowska, R. K., Przanowski, P., Wang, L., Nguyen, B., Walavalkar, N. M., Duarte, F. M., & Guertin, M. J. (2023) · Genome Research · doi:10.1101/gr.277559.122 · Cited by 16
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Chao, Y., Gao, L., Wang, X., Cai, Y., Shu, Y., Zou, X., Qin, Y., Hu, C., Dai, Y.-L., Zhu, M., et al. (2022) · Metabolism · doi:10.1016/j.metabol.2022.155295 · Cited by 15
Bonilla-Carvajal, K., Stashenko, E. E., & Moreno‐Castellanos, N. (2022) · Current Issues in Molecular Biology · doi:10.3390/cimb44110389 · Cited by 15
Conti, G., Calderan, L., Sierra, L. A. Q., Conti, A., Ossanna, R., Boschi, F., Marzola, P., Ferrarini, F., Governa, M., Lievens, P., et al. (2022) · Tissue and Cell · doi:10.1016/j.tice.2022.101990 · Cited by 15
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Flori, L., Piragine, E., Calderone, V., & Testai, L. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122491 · Cited by 15
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Lyu, Z., Chan, Y.-T., Lu, Y., Lam, T. F., Wu, X., Wu, J., Xu, L., Yang, W., Zhang, C., Zhong, L. L. D., et al. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.06.018 · Cited by 15
Cucoreanu, C., Țigu, A. B., Nistor, M., Moldovan, R.-C., Pralea, I.-E., Iacobescu, M., Iuga, C. A., Szabó, R., Dindelegan, G., & Ciuce, C. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46070441 · Cited by 15
Sánchez‐Trasviña, C., Lorenzo-Anota, H. Y., Escobar-Fernández, A. M., Lezama-Aguilar, D., Morales-Martínez, A., Vélez-Barceló, A., Benavides, J., Lozano, O., Rito‐Palomares, M., & Mayolo‐Deloisa, K. (2024) · ACS Omega · doi:10.1021/acsomega.4c07203 · Cited by 15
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Liu, M.-C., Logan, H., & Newman, J. J. (2020) · Molecular Biology Reports · doi:10.1007/s11033-020-05884-8 · Cited by 15
Abdalla, B. A., Chen, X., Li, K., Chen, J., Yi, Z., Zhang, X., Li, Z., & Nie, Q. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118858 · Cited by 15
Leachman, J. R., Cincinelli, C., Ahmed, N., Dalmasso, C., Xu, M., Gatineau, E., Nikolajczyk, B. S., Yiannikouris, F. B., Hinds, T. D., & Loria, A. S. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120718 · Cited by 15
Li, J., Wang, X., Meng, X., Zhou, X., Huang, H., Feng, Y., Fu, Y., Liu, X., & Yu, B. (2023) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2023.110364 · Cited by 15
Khamis, A., Boutry, R., Canouil, M., Mathew, S., Lobbens, S., Crouch, H. K., Andrew, T., Abderrahmani, A., Tamanini, F., & Froguel, P. (2020) · Clinical Epigenetics · doi:10.1186/s13148-020-00858-w · Cited by 16
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Forst, T. M., Block, C. E. M. D., Prato, S. D., Frías, J. P., Lautenbach, A., Ludvik, B. H., Marinez, M., Mathieu, C., Müller, T. D., & Schnell, O. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16247 · Cited by 15
Xu, J., Jia, S., Ren, Y., Zhang, Y., Zhang, J., Tang, C., Kan, J., Liu, J., & Wang, Y. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.106769 · Cited by 14
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Metadata
- Authors
- Ghaben, A. L., & Scherer, P. E.
- Affiliations
- The University of Texas Southwestern Medical Center (US)
- Corresponding author
- Scherer, Philipp E.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2019-01-04
- Volume
- 20
- Issue
- 4
- Pages
- 242-258
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W2908320623
- Semantic Scholar
- 4fcd08092b207de7bf166354cd3000e12504500a
- Cited by
- 1,395
- References
- 248
- Citations by year
- 2026: 128 · 2025: 209 · 2024: 212 · 2023: 218 · 2022: 219 · 2021: 207 · 2020: 140 · 2019: 61
- FWCI
- 18.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nature Reviews Molecular Cell Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Peroxisome Proliferator-Activated Receptors
- Keywords
- adipogenesis, obesity, metabolic health, adipocyte hypertrophy, adipocyte hyperplasia, adipose tissue expansion, white adipose tissue, metabolic disorders, cancer risk
- MeSH terms
- Animals, Cell Differentiation, Health, Humans, Obesity, Signal Transduction, Adipocytes, Adipogenesis
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