CoChat
Sign Up
Cited by 521

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Tobacco smoking and somatic mutations in human bronchial epithelium

Yoshida, Kenichi, Gowers, Kate H. C., Lee-Six, Henry, Chandrasekharan, Deepak P., Coorens, Tim, Maughan, Elizabeth F., Beal, Kathryn, Menzies, Andrew, Millar, Fraser R., Anderson, Elizabeth, Clarke, Sarah E., Pennycuick, Adam, Thakrar, Ricky M., Butler, Colin R., Kakiuchi, Nobuyuki, Hirano, Tomonori, Hynds, Robert E., Stratton, Michael R., Martincorena, Iñigo, Janes, Sam M., Campbell, Peter J.·2020·Nature
DOI 10.1038/s41586-020-1961-1PMC PMC7021511
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1038/s41586-020-1961-1

Cites

12 of 12 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 12 references

Research works printed but not linked: 39

  1. Alberg, A. J., Brock, M. V., Ford, J. G., Samet, J. M. & Spivack, S. D. Epidemiology of lung cancer. Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 143, e1S–e29S (2013). · DOI
  2. Peto, R. et al. Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of national statistics with two case-control studies. Br. Med. J. 321, 323–329 (2000). · DOI
  3. International Agency for Research on Cancer. Tobacco Smoke and Involuntary Smoking. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Vol. 83 (IARC and World Health Organization, 2004).
  4. Hecht, S. S. Progress and challenges in selected areas of tobacco carcinogenesis. Chem. Res. Toxicol. 21, 160–171 (2008). · DOI
  5. Pfeifer, G. P. et al. Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers. Oncogene 21, 7435–7451 (2002). · DOI
  6. Pleasance, E. D. et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature 463, 184–190 (2010). · DOI
  7. George, J. et al. Comprehensive genomic profiles of small cell lung cancer. Nature 524, 47–53 (2015). · DOI
  8. Tomasetti, C., Marchionni, L., Nowak, M. A., Parmigiani, G. & Vogelstein, B. Only three driver gene mutations are required for the development of lung and colorectal cancers. Proc. Natl Acad. Sci. USA 112, 118–123 (2015). · DOI
  9. Martincorena, I. et al. Universal patterns of selection in cancer and somatic tissues. Cell 171, 1029–1041.e21 (2017). · DOI · Paper page
  10. Campbell, J. D. et al. Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas. Nat. Genet. 48, 607–616 (2016). · DOI · Paper page
  11. Garfinkel, L. & Stellman, S. D. Smoking and lung cancer in women: findings in a prospective study. Cancer Res. 48, 6951–6955 (1988).
  12. Armitage, P. Response to Richard Doll: the age distribution of cancer. J. Roy. Stat. Soc. A 134, 155–156 (1971).
  13. Doll, R. & Peto, R. Cigarette smoking and bronchial carcinoma: dose and time relationships among regular smokers and lifelong non-smokers. J. Epidemiol. Community Health 32, 303–313 (1978). · DOI
  14. Kucab, J. E. et al. A compendium of mutational signatures of environmental agents. Cell 177, 821–836 (2019). · DOI · Paper page
  15. Petljak, M. et al. Characterizing mutational signatures in human cancer cell lines reveals episodic APOBEC mutagenesis. Cell 176, 1282–1294 (2019). · DOI
  16. Haradhvala, N. J. et al. Mutational strand asymmetries in cancer genomes reveal mechanisms of DNA damage and repair. Cell 164, 538–549 (2016). · DOI
  17. Letouzé, E. et al. Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis. Nat. Commun. 8, 1315 (2017). · DOI
  18. Alexandrov, L. et al. The repertoire of mutational signatures in human cancer. Nature https://doi.org/10.1038/s41586-020-1943-3 (2020). · DOI · Paper page
  19. Martincorena, I. et al. Somatic mutant clones colonize the human esophagus with age. Science 362, 911–917 (2018). · DOI · Paper page
  20. Brunner, S. F. et al. Somatic mutations and clonal dynamics in healthy and cirrhotic human liver. Nature 574, 538–542 (2019). · DOI · Paper page
  21. Teixeira, V. H. et al. Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors. eLife 2, e00966 (2013). · DOI
  22. Hegab, A. E. et al. Novel stem/progenitor cell population from murine tracheal submucosal gland ducts with multipotent regenerative potential. Stem Cells 29, 1283–1293 (2011). · DOI
  23. Tata, A. et al. Myoepithelial cells of submucosal glands can function as reserve stem cells to regenerate airways after injury. Cell Stem Cell 22, 668–683 (2018). · DOI
  24. Lynch, T. J. et al. Submucosal gland myoepithelial cells are reserve stem cells that can regenerate mouse tracheal epithelium. Cell Stem Cell 22, 653–667 (2018). · DOI
  25. Gowers, K. H. C. et al. Optimized isolation and expansion of human airway epithelial basal cells from endobronchial biopsy samples. J. Tissue Eng. Regen. Med. 12, e313–e317 (2018). · DOI
  26. Butler, C. R. et al. Rapid expansion of human epithelial stem cells suitable for airway tissue engineering. Am. J. Respir. Crit. Care Med. 194, 156–168 (2016). · DOI
  27. Teixeira, V. H. et al. Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions. Nat. Med. 25, 517–525 (2019). · DOI
  28. Jones, D. et al. cgpCaVEManWrapper: simple execution of CaVEMan in order to detect somatic single nucleotide variants in NGS data. Curr. Protoc. Bioinformatics 56, 15.10.1–15.10.18 (2016). · DOI
  29. Gerstung, M., Papaemmanuil, E. & Campbell, P. J. Subclonal variant calling with multiple samples and prior knowledge. Bioinformatics 30, 1198–1204 (2014). · DOI
  30. Yang, H. & Wang, K. Genomic variant annotation and prioritization with ANNOVAR and wANNOVAR. Nat. Protoc. 10, 1556–1566 (2015). · DOI
  31. Raine, K. M. et al. cgpPindel: identifying somatically acquired insertion and deletion events from paired end sequencing. Curr. Protoc. Bioinformatics 52, 15.7.1–15.7.12 (2015). · DOI
  32. Campbell, P. J. et al. Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nat. Genet. 40, 722–729 (2008). · DOI
  33. Raine, K. M. et al. ascatNgs: identifying somatically acquired copy-number alterations from whole-genome sequencing data. Curr. Protoc. Bioinformatics 56, 15.9.1–15.9.17 (2016). · DOI
  34. Van Loo, P. et al. Allele-specific copy number analysis of tumors. Proc. Natl Acad. Sci. USA 107, 16910–16915 (2010). · DOI
  35. Buels, R. et al. JBrowse: a dynamic web platform for genome visualization and analysis. Genome Biol. 17, 66 (2016). · DOI
  36. Baca, S. C. et al. Punctuated evolution of prostate cancer genomes. Cell 153, 666–677 (2013). · DOI
  37. Stephens, P. J. et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144, 27–40 (2011). · DOI · Paper page
  38. Li, Y. et al. Patterns of somatic structural variation in human cancer genomes. Nature https://doi.org/10.1038/s41586-019-1913-9 (2020). · DOI · Paper page
  39. Farmery, J. H. R. et al. Telomerecat: a ploidy-agnostic method for estimating telomere length from whole genome sequencing data. Sci. Rep. 8, 1300 (2018). · DOI

Cited by

See all 521

Metadata

Authors
Yoshida, K., Gowers, K. H. C., Lee-Six, H., Chandrasekharan, D. P., Coorens, T., Maughan, E. F., Beal, K., Menzies, A., Millar, F. R., Anderson, E., Clarke, S. E., Pennycuick, A., Thakrar, R. M., Butler, C. R., Kakiuchi, N., Hirano, T., Hynds, R. E., Stratton, M. R., Martincorena, I., Janes, S. M., & Campbell, P. J.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
2020-01-29
Volume
578
Issue
7794
Pages
266-272
ISSN
  • 0028-0836
  • 1476-4687
DOI
10.1038/s41586-020-1961-1
PMC
PMC7021511
Cited by
521
References
12
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Tobacco smoking and somatic mutations in human bronchial epithelium. https://app.cochat.ai/papers/10.1038/s41586-020-1961-1
The paper
Yoshida, K., Gowers, K. H. C., Lee-Six, H., Chandrasekharan, D. P., Coorens, T., Maughan, E. F., Beal, K., Menzies, A., Millar, F. R., Anderson, E., Clarke, S. E., Pennycuick, A., Thakrar, R. M., Butler, C. R., Kakiuchi, N., Hirano, T., Hynds, R. E., Stratton, M. R., Martincorena, I., . . . Campbell, P. J. (2020). Tobacco smoking and somatic mutations in human bronchial epithelium. Nature. https://doi.org/10.1038/s41586-020-1961-1