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Aggression experience and observation drive shared behavioural and neural changes

Iravedra-García, Jorge M., Guthman, Eartha Mae, Tsin, Dexter, Cherepanova, Polina, Cuturela, Lenca, Ocasio-Arce, Edgar J., Pillow, Jonathan W., Falkner, Annegret L.·2026·Nature
DOI 10.1038/s41586-026-11217-9
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  1. Olsson, A., Knapska, E. & Lindström, B. The neural and computational systems of social learning. Nat. Rev. Neurosci. 21, 197–212 (2020). · DOI
  2. Boone, T., Reilly, A. J. & Sashkin, M. Social learning theory. Group Organ. Stud. 2, 384–385 (1977). · DOI
  3. Bandura, A., Ross, D. & Ross, S. A. Vicarious reinforcement and imitative learning. J. Abnorm. Psychol. 67, 601–607 (1963).
  4. Yang, T. et al. Hypothalamic neurons that mirror aggression. Cell 186, 1195–1211 (2023). · DOI
  5. Vinograd, A., Nair, A., Kim, J. H., Linderman, S. W. & Anderson, D. J. Causal evidence of a line attractor encoding an affective state. Nature 634, 910–918 (2024). · DOI
  6. Li, X. et al. Violence exposure across multiple contexts as predictors of reactive and proactive aggression in Chinese preadolescents. Aggress. Behav. 48, 319–330 (2022). · DOI
  7. Wall Myers, T. D. et al. Understanding the link between exposure to violence and aggression in justice-involved adolescents. Dev. Psychopathol. 30, 593–603 (2018). · DOI
  8. Suzuki, H. & Lucas, L. R. Chronic passive exposure to aggression escalates aggressiveness of rat observers. Aggress. Behav. 36, 54–66 (2010). · DOI
  9. Williamson, C. M., Romeo, R. D. & Curley, J. P. Dynamic changes in social dominance and mPOA GnRH expression in male mice following social opportunity. Horm. Behav. 87, 80–88 (2017). · DOI · Paper page
  10. Willmore, L., Cameron, C., Yang, J., Witten, I. B. & Falkner, A. L. Behavioural and dopaminergic signatures of resilience. Nature 611, 124–132 (2022). · DOI
  11. Zhukovskaya, A. et al. Heightened lateral habenula activity during stress produces brainwide and behavioral substrates of susceptibility. Neuron https://doi.org/10.1016/j.neuron.2024.09.009 (2024). · DOI
  12. Rizzolatti, G. & Craighero, L. The mirror-neuron system. Annu. Rev. Neurosci. 27, 169–192 (2004). · DOI · Paper page
  13. Lo, L. et al. Connectional architecture of a mouse hypothalamic circuit node controlling social behavior. Proc. Natl Acad. Sci. USA 116, 7503–7512 (2019). · DOI
  14. Karigo, T. et al. Distinct hypothalamic control of same- and opposite-sex mounting behaviour in mice. Nature 589, 258–263 (2021). · DOI
  15. Golden, S. A. et al. Basal forebrain projections to the lateral habenula modulate aggression reward. Nature 534, 688–692 (2016). · DOI
  16. Kashtelyan, V., Lichtenberg, N. T., Chen, M. L., Cheer, J. F. & Roesch, M. R. Observation of reward delivery to a conspecific modulates dopamine release in ventral striatum. Curr. Biol. 24, 2564–2568 (2014). · DOI
  17. Stagkourakis, S., Spigolon, G., Liu, G. & Anderson, D. J. Experience-dependent plasticity in an innate social behavior is mediated by hypothalamic LTP. Proc. Natl Acad. Sci. USA 117, 25789–25799 (2020). · DOI
  18. Nordman, J. et al. Potentiation of divergent medial amygdala pathways drives experience-dependent aggression escalation. J. Neurosci. https://doi.org/10.1523/JNEUROSCI.0370-20.2020 (2020). · DOI
  19. de Moura Oliveira, V. E., Evrard, F., Faure, M. C. & Bakker, J. Social isolation and aggression training lead to escalated aggression and hypothalamus-pituitary-gonad axis hyperfunction in mice. Neuropsychopharmacology 49, 1266–1275 (2024). · DOI
  20. Yan, R. et al. The multi-stage plasticity in the aggression circuit underlying the winner effect. Cell 187, 6785–6803.e18 (2024). · DOI
  21. Falkner, A. L., Grosenick, L., Davidson, T. J., Deisseroth, K. & Lin, D. Hypothalamic control of male aggression-seeking behavior. Nat. Neurosci. 19, 596–604 (2016). · DOI
  22. Minakuchi, T. et al. Independent inhibitory control mechanisms for aggressive motivation and action. Nat. Neurosci. 27, 702–715 (2024). · DOI
  23. Wong, L. C. et al. Effective modulation of male aggression through lateral septum to medial hypothalamus projection. Curr. Biol. 26, 593–604 (2016). · DOI · Paper page
  24. Barbier, M. et al. Projections from the dorsomedial division of the bed nucleus of the Stria terminalis to hypothalamic nuclei in the mouse. J. Comp. Neurol. https://doi.org/10.1002/cne.24988 (2020). · DOI
  25. Yamamoto, R., Ahmed, N., Ito, T., Gungor, N. Z. & Pare, D. Optogenetic study of anterior BNST and basomedial amygdala projections to the ventromedial hypothalamus. eNeuro 5, ENEURO.0204-18.2018 (2018). · DOI
  26. Hong, W., Kim, D.-W. & Anderson, D. J. Antagonistic control of social versus repetitive self-grooming behaviors by separable amygdala neuronal subsets. Cell 158, 1348–1361 (2014). · DOI · Paper page
  27. Pereira, T. D. et al. SLEAP: A deep learning system for multi-animal pose tracking. Nat. Methods 19, 486–495 (2022). · DOI
  28. Koolhaas, J. M. et al. Coping styles in animals: current status in behavior and stress-physiology. Neurosci. Biobehav. Rev. 23, 925–935 (1999). · DOI · Paper page
  29. Klibaite, U., Berman, G. J., Cande, J., Stern, D. L. & Shaevitz, J. W. An unsupervised method for quantifying the behavior of paired animals. Phys. Biol. 14, 015006 (2017). · DOI
  30. Guthman, E. M., Iravedra-Garcia, J. M., Sirrs, L., Le, A. & Falkner, A. L. Context rescales a social action code in a hormone-sensitive network. Preprint at bioRxiv https://doi.org/10.1101/2025.09.24.678271 (2025). · DOI
  31. Sych, Y., Chernysheva, M., Sumanovski, L. T. & Helmchen, F. High-density multi-fiber photometry for studying large-scale brain circuit dynamics. Nat. Methods 16, 553–560 (2019). · DOI
  32. Kim, C. K. et al. Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain. Nat. Methods 13, 325–328 (2016). · DOI
  33. Yang, B., Karigo, T. & Anderson, D. J. Transformations of neural representations in a social behaviour network. Nature 608, 741–749 (2022). · DOI · Paper page
  34. Sun, F. et al. A genetically encoded fluorescent sensor enables rapid and specific detection of dopamine in flies, fish, and mice. Cell 174, 481–496 (2018). · DOI · Paper page
  35. Williams, A. H. et al. Discovering precise temporal patterns in large-scale neural recordings through robust and interpretable time warping. Neuron 105, 246–259 (2020). · DOI · Paper page
  36. Yamaguchi, T. & Lin, D. Functions of medial hypothalamic and mesolimbic dopamine circuitries in aggression. Curr. Opin. Behav. Sci. 24, 104–112 (2018). · DOI
  37. Adjei, M. P. et al. Familiarity gates socially transmitted aggression via the medial amygdala. J. Neurosci. 45, e1018252025 (2025). · DOI
  38. Dupré la Tour, T., Eickenberg, M., Nunez-Elizalde, A. O. & Gallant, J. L. Feature-space selection with banded ridge regression. Neuroimage 264, 119728 (2022). · DOI
  39. Roth, B. L. DREADDs for neuroscientists. Neuron 89, 683–694 (2016). · DOI · Paper page
  40. Berkowitz, L. Aggression: Its Causes, Consequences, and Control (McGraw-Hill, 1993).
  41. Hamid, A. A. et al. Mesolimbic dopamine signals the value of work. Nat. Neurosci. 19, 117–126 (2016). · DOI
  42. Warren, B. L. et al. Neurobiological sequelae of witnessing stressful events in adult mice. Biol. Psychiatry 73, 7–14 (2013). · DOI · Paper page
  43. Nakatake, Y. et al. The effects of emotional stress are not identical to those of physical stress in mouse model of social defeat stress. Neurosci. Res. 158, 56–63 (2020). · DOI
  44. Sial, O. K., Warren, B. L., Alcantara, L. F., Parise, E. M. & Bolaños-Guzmán, C. A. Vicarious social defeat stress: bridging the gap between physical and emotional stress. J. Neurosci. Methods 258, 94–103 (2016). · DOI
  45. Tomasello, M. Emulation learning and cultural learning. Behav. Brain Sci. 21, 703–704 (1998). · DOI
  46. Mondoloni, S. et al. Serotonin release in the habenula during emotional contagion promotes resilience. Science 385, 1081–1086 (2024). · DOI
  47. Vong, L. et al. Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons. Neuron 71, 142–154 (2011). · DOI
  48. Lee, H. et al. Scalable control of mounting and attack by Esr1+ neurons in the ventromedial hypothalamus. Nature 509, 627–632 (2014). · DOI · Paper page
  49. Friard, O. & Gamba, M. BORIS: a free, versatile open-source event-logging software for video/audio coding and live observations. Methods Ecol. Evol. 7, 1325–1330 (2016). · DOI
  50. Bohnslav, J. P. et al. DeepEthogram, a machine learning pipeline for supervised behavior classification from raw pixels. eLife 10, e63377 (2021). · DOI
  51. Sun, J. J. et al. The multi-agent behavior dataset: mouse dyadic social interactions. Adv. Neural Inf. Process. Syst. 2021, 1–15 (2021).
  52. Woo, S., Park, J., Lee, J.-Y. & Kweon, I. S. CBAM: convolutional block attention module. In Computer Vision—ECCV 2018 3–19 (Springer, 2018). · DOI · Paper page
  53. Fang, Y.-Y., Yamaguchi, T., Song, S. C., Tritsch, N. X. & Lin, D. A hypothalamic midbrain pathway essential for driving maternal behaviors. Neuron 98, 192–207 (2018). · DOI
  54. Guthman, E. M. et al. Two-color multifiber photometry recordings of the social behavior network in mice. J. Vis. Exp. 229, e70049 (2026). · DOI
  55. Zhang, Z.-M., Chen, S. & Liang, Y.-Z. Baseline correction using adaptive iteratively reweighted penalized least squares. Analyst 135, 1138–1146 (2010). · DOI
  56. Lundberg, S. & Lee, S.-I. A unified approach to interpreting model predictions. Preprint at https://doi.org/10.48550/arXiv.1705.07874 (2017). · DOI · Paper page
  57. Kobak, D. et al. Demixed principal component analysis of neural population data. eLife 5, e10989 (2016). · DOI
  58. Semedo, J. D., Zandvakili, A., Machens, C. K., Yu, B. M. & Kohn, A. Cortical areas interact through a communication subspace. Neuron 102, 249–259 (2019). · DOI
  59. Pisano, T. J. et al. Homologous organization of cerebellar pathways to sensory, motor, and associative forebrain. Cell Rep. 36, 109721 (2021). · DOI
  60. Chon, U., Vanselow, D. J., Cheng, K. C. & Kim, Y. Enhanced and unified anatomical labeling for a common mouse brain atlas. Nat. Commun. 10, 5067 (2019). · DOI

Metadata

Authors
Iravedra-García, J. M., Guthman, E. M., Tsin, D., Cherepanova, P., Cuturela, L., Ocasio-Arce, E. J., Pillow, J. W., & Falkner, A. L.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
2026-11-04
ISSN
  • 0028-0836
  • 1476-4687
DOI
10.1038/s41586-026-11217-9
Cited by
0
References
5
Language
en
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CoChat. (2026). Citation check: Aggression experience and observation drive shared behavioural and neural changes. https://app.cochat.ai/papers/10.1038/s41586-026-11217-9
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Iravedra-García, J. M., Guthman, E. M., Tsin, D., Cherepanova, P., Cuturela, L., Ocasio-Arce, E. J., Pillow, J. W., & Falkner, A. L. (2026). Aggression experience and observation drive shared behavioural and neural changes. Nature. https://doi.org/10.1038/s41586-026-11217-9