Cortico–reticulo–spinal circuit reorganization enables functional recovery after severe spinal cord contusion

Structural and molecular interrogation of intact biological systems

Chung, K., Wallace, J., Kim, S.-Y., Kalyanasundaram, S., Andalman, A. S., Davidson, T. J., Mirzabekov, J. J., Zalocusky, K. A., Mattis, J., Denisin, A. K., et al. (2013) · Nature · doi:10.1038/nature12107 · Cited by 2,008

DREADDs for neuroscientists

Roth, B. L. (2016) · Neuron · doi:10.1016/j.neuron.2016.01.040 · Cited by 1,742

Graded Histological and Locomotor Outcomes after Spinal Cord Contusion Using the NYU Weight-Drop Device versus Transection

Basso, D. M., Beattie, M. S., & Bresnahan, J. C. (1996) · Experimental Neurology · doi:10.1006/exnr.1996.0098 · Cited by 1,470

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

Tervo, D. G. R., Hwang, B., Viswanathan, S., Gaj, T., Lavzin, M., Ritola, K., Lindo, S. E., Michael, S. C., Кулешова, Е. П., Ojala, D. S., et al. (2016) · Neuron · doi:10.1016/j.neuron.2016.09.021 · Cited by 1,220

The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats

Bareyre, F. M., Kerschensteiner, M., Raineteau, O., Mettenleiter, T. C., Weinmann, O., & Schwab, M. E. (2004) · Nature Neuroscience · doi:10.1038/nn1195 · Cited by 1,088

Chemogenetics revealed: DREADD occupancy and activation via converted clozapine

Gomez, J. L., Bonaventura, J., Lesniak, W., Mathews, W. B., Sysa-Shah, P., Rodriguez, L. A., Ellis, R. J., Richie, C. T., Harvey, B. K., Dannals, R. F., et al. (2017) · Science · doi:10.1126/science.aan2475 · Cited by 980

Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury

Lu, P., Wang, Y., Graham, L., McHale, K., Gao, M., Wu, D., Brock, J., Blesch, A., Rosenzweig, E. S., Havton, L. A., et al. (2012) · Cell · doi:10.1016/j.cell.2012.08.020 · Cited by 908

LOCOMOTOR CIRCUITS IN THE MAMMALIAN SPINAL CORD

Kiehn, O. (2006) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112910 · Cited by 868

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

Tomer, R., Ye, L., Hsueh, B., & Deisseroth, K. (2014) · Nature Protocols · doi:10.1038/nprot.2014.123 · Cited by 842

Restoring Voluntary Control of Locomotion after Paralyzing Spinal Cord Injury

van den Brand, R., Heutschi, J., Barraud, Q., DiGiovanna, J., Bartholdi, K., Huerlimann, M., Friedli, L., Vollenweider, I., Moraud, E. M., Duis, S., et al. (2012) · Science · doi:10.1126/science.1217416 · Cited by 767

Plasticity in Cervical Motor Circuits following Spinal Cord Injury and Rehabilitation

Walker, J., & Detloff, M. R. (2021) · Biology · doi:10.3390/biology10100976 · Cited by 29

Boldine modulates glial transcription and functional recovery in a murine model of contusion spinal cord injury

Toro, C. A., Johnson, K., Hansen, J., Siddiq, M. M., Vásquez, W., Zhao, W., Graham, Z., Sáez, J. C., Iyengar, R., & Cardozo, C. P. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1163436 · Cited by 25

Meeting Proceedings for SCI 2020: Launching a Decade of Disruption in Spinal Cord Injury Research

Morse, L. R., Field-Fote, E. C., Contreras-Vidal, J. L., Noble‐Haeusslein, L. J., Rodreick, M., SCI 2020 Working Group, Shields, R. K., Sofroniew, M. V., Wudlick, R., Zanca, J. M., et al. (2020) · Journal of Neurotrauma · doi:10.1089/neu.2020.7174 · Cited by 27

Reduction of prolonged excitatory neuron swelling after spinal cord injury improves locomotor recovery in mice

Li, Q., Sandoval, A., Moth, J., Shang, J., Liew, J. Y., Dunn, T. J., Yang, Z., Su, J., Henwood, M. K., Williams, P. R., et al. (2024) · Science Translational Medicine · doi:10.1126/scitranslmed.adn7095 · Cited by 24

Reaching and Grasping Training Improves Functional Recovery After Chronic Cervical Spinal Cord Injury

Gallegos, C. M., Carey, M., Zheng, Y., He, X., & Cao, Q. L. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00110 · Cited by 24

The Translesional Spinal Network and Its Reorganization after Spinal Cord Injury

Krůpa, P., Siddiqui, A. M., Grahn, P. J., Islam, R., Chen, B. K., Madigan, N. N., Windebank, A. J., & Lavrov, I. A. (2020) · The Neuroscientist · doi:10.1177/1073858420966276 · Cited by 22

Crossing nerve transfer drives sensory input–dependent plasticity for motor recovery after brain injury

Gao, Z., Pang, Z., Lei, G., Chen, Y., Cai, Z., Zhu, S., Lin, W., Qiu, Z., Wang, Y., Shen, Y., et al. (2022) · Science Advances · doi:10.1126/sciadv.abn5899 · Cited by 28

Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury

Aljović, A., Jacobi, A., Marcantoni, M., Kagerer, F., Loy, K., Kendirli, A., Bräutigam, J., Fabbio, L., Steenbergen, V. V., Pleśniar, K., et al. (2023) · EMBO Molecular Medicine · doi:10.15252/emmm.202216111 · Cited by 24

Functional plasticity of glutamatergic neurons of medullary reticular nuclei after spinal cord injury in mice

Lemieux, M., Karimi, N., & Bretzner, F. (2024) · Nature Communications · doi:10.1038/s41467-024-45300-4 · Cited by 26

Systematic Evaluation of Spinal Cord Injury Animal Models in the Field of Biomaterials

Verstappen, K., Aquarius, R., Klymov, A., Wever, K. E., Damveld, L., Leeuwenburgh, S. C. G., Bartels, R., Hooijmans, C. R., & Walboomers, X. F. (2021) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2021.0194 · Cited by 24

Alternative routes for recovery of hand functions after corticospinal tract injury in primates and rodents

Isa, T., Mitsuhashi, M., & Yamaguchi, R. (2019) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000749 · Cited by 22

Preclinical upper limb neurorobotic platform to assess, rehabilitate, and develop therapies

Pasquini, M., James, N. D., Dewany, I., Coen, F.-V., Cho, N., Lai, S., Anil, S., Carpaneto, J., Barraud, Q., Lacour, S. P., et al. (2022) · Science Robotics · doi:10.1126/scirobotics.abk2378 · Cited by 21

Chronic inactivation of the contralesional hindlimb motor cortex after thoracic spinal cord hemisection impedes locomotor recovery in the rat

Brown, A. R., & Martinez, M. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113775 · Cited by 20

Functional Contribution of Mesencephalic Locomotor Region Nuclei to Locomotor Recovery After Spinal Cord Injury

Roussel, M., Lafrance-Zoubga, D., Josset, N., Lemieux, M., & Bretzner, F. (2022) · Cell Reports Medicine · doi:10.1016/j.xcrm.2023.100946 · Cited by 20

PTEN knockout using retrogradely transported AAVs transiently restores locomotor abilities in both acute and chronic spinal cord injury

Stewart, A. N., Kumari, R., Bailey, W. M., Glaser, E. P., Bosse-Joseph, C. C., Park, K. A., Hammers, G. V., Wireman, O. H., & Gensel, J. C. (2023) · Experimental Neurology · doi:10.1016/j.expneurol.2023.114502 · Cited by 20

Rehabilitation enhances epothilone-induced locomotor recovery after spinal cord injury

Griffin, J. M., Hingorani Jai Prakash, S., Bockemühl, T., Benner, J. M., Schaffran, B., Moreno-Manzano, V., Büschges, A., & Bradke, F. (2022) · Brain Communications · doi:10.1093/braincomms/fcad005 · Cited by 19

Diversity of reticulospinal systems in mammals

Perreault, M., & Giorgi, A. U. D. (2019) · Current Opinion in Physiology · doi:10.1016/j.cophys.2019.03.001 · Cited by 21

Brain-Computer Interface, Neuromodulation, and Neurorehabilitation Strategies for Spinal Cord Injury

Cajigas, I., & Vedantam, A. (2021) · Neurosurgery Clinics of North America · doi:10.1016/j.nec.2021.03.012 · Cited by 23

Vestibulospinal and Corticospinal Modulation of Lumbosacral Network Excitability in Human Subjects

Sayenko, D. G., Atkinson, D. A., Mink, A. M., Gurley, K. M., Edgerton, V. R., Harkema, S. J., & Gerasimenko, Y. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01746 · Cited by 19

Regulatory T cells in neurological disorders and tissue regeneration: Mechanisms of action and therapeutic potentials

Jie, J., Yao, X., Deng, H., Zhou, Y., Jiang, X., DAI, X. H., Yang, Y., & Yang, P. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-01363 · Cited by 21

Chemogenetic stimulation of proprioceptors remodels lumbar interneuron excitability and promotes motor recovery after SCI

Gao, Z., Yang, Y., Feng, Z., Li, X., Min, C., Zhu, Z., Song, H. K., Hu, Y., Wang, Y., & He, X. (2021) · Molecular Therapy · doi:10.1016/j.ymthe.2021.04.023 · Cited by 17

Lateral Corticospinal Tract and Dorsal Column Damage: Predictive Relationships With Motor and Sensory Scores at Discharge From Acute Rehabilitation After Spinal Cord Injury

Smith, A. C., O’Dell, D. R., Albin, S. R., Berliner, J. C., Dungan, D., Robinson, E., Elliott, J. M., Carballido‐Gamio, J., Stevens‐Lapsley, J. E., & Weber, K. A., II (2021) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2021.07.792 · Cited by 18

Passive Clearing and 3D Lightsheet Imaging of the Intact and Injured Spinal Cord in Mice

McCreedy, D. A., Jalufka, F. L., Platt, M. E., Min, S., Kirchhoff, M. A., Pritchard, A. L., Reid, S. K., Manlapaz, R., Mihaly, E., Butts, J. C., et al. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.684792 · Cited by 19

Spinal maps of motoneuron activity during human locomotion: neuromechanical considerations

Avaltroni, P., Cappellini, G., Labini, F. S., Ivanenko, Y. P., & Lacquaniti, F. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1389436 · Cited by 18

Intraspinal Plasticity Associated With the Development of Autonomic Dysreflexia After Complete Spinal Cord Injury

Michael, F. M., Patel, S. P., & Rabchevsky, A. G. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00505 · Cited by 18

Recovery of Forearm and Fine Digit Function After Chronic Spinal Cord Injury by Simultaneous Blockade of Inhibitory Matrix Chondroitin Sulfate Proteoglycan Production and the Receptor PTPσ

Milton, A. J., Kwok, J. C. F., McClellan, J., Randall, S., Lathia, J. D., Warren, P. M., Silver, D. J., & Silver, J. (2023) · Journal of Neurotrauma · doi:10.1089/neu.2023.0117 · Cited by 19

Derivation of Specific Neural Populations From Pluripotent Cells for Understanding and Treatment of Spinal Cord Injury

White, N., & Sakiyama‐Elbert, S. E. (2018) · Developmental Dynamics · doi:10.1002/dvdy.24680 · Cited by 17

The diversity and plasticity of descending motor pathways rewired after stroke and trauma in rodents

Inoue, T., & Ueno, M. (2025) · Frontiers in Neural Circuits · doi:10.3389/fncir.2025.1566562 · Cited by 21

The Overexpression of Insulin-Like Growth Factor-1 and Neurotrophin-3 Promote Functional Recovery and Alleviate Spasticity After Spinal Cord Injury

Talifu, Z., Qin, C., Xin, Z., Chen, Y., Liu, J., Dangol, S., Ma, X., Gong, H., Pei, Z., Yu, Y. H., et al. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.863793 · Cited by 16

The Promising Role of a Zebrafish Model Employed in Neural Regeneration Following a Spinal Cord Injury

Zeng, C., & Tsai, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241813938 · Cited by 16

Combinatorial therapies for spinal cord injury: strategies to induce regeneration

Salgado, A., Gomes, E., & Silva, N. (2018) · Neural Regeneration Research · doi:10.4103/1673-5374.243705 · Cited by 16

A brainstem bypass for spinal cord injury

Hilton, B. J., & Tetzlaff, W. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0099-z · Cited by 15

Highly Sensitive Microstructure-Based Flexible Pressure Sensor for Quantitative Evaluation of Motor Function Recovery after Spinal Cord Injury

Yang, D., Yang, W. M., Li, L., Zhou, K., Hao, M., Feng, X., Zhang, T., & Liu, Y. (2019) · Sensors · doi:10.3390/s19214673 · Cited by 14

Chemogenetic modulation of sensory afferents induces locomotor changes and plasticity after spinal cord injury

Eisdorfer, J. T., Sobotka-Briner, H., Schramfield, S., Moukarzel, G., Chen, J., Campion, T. J., III, Smit, R. D., Rauscher, B. C., Lemay, M. A., Smith, G. M., et al. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.872634 · Cited by 14

Harnessing spinal circuit reorganization for targeted functional recovery after spinal cord injury

Sun, X., Li, L., Huang, L., Li, Y., Wang, L., & Wei, Q. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.106854 · Cited by 16

Rehabilitation Training after Spinal Cord Injury Affects Brain Structure and Function: From Mechanisms to Methods

He, L., Guo, X.-J., Zhao, C., & Rao, J. (2023) · Biomedicines · doi:10.3390/biomedicines12010041 · Cited by 15

Longitudinal interrogation of sympathetic neural circuits and hemodynamics in preclinical models

Soriano, J. E., Hudelle, R., Squair, J. W., Mahe, L., Amir, S., Gautier, M., Perez-Puchalt, V., Barraud, Q., Phillips, A. A., & Courtine, G. (2022) · Nature Protocols · doi:10.1038/s41596-022-00764-w · Cited by 13

Muscle Activation Patterns During Movement Attempts in Children With Acquired Spinal Cord Injury: Neurophysiological Assessment of Residual Motor Function Below the Level of Lesion

Atkinson, D. A., Méndez, L., Goodrich, N., Aslan, S. C., Ugiliweneza, B., & Behrman, A. L. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.01295 · Cited by 14

Uncovering and leveraging the return of voluntary motor programs after paralysis using a bi-cortical neuroprosthesis

Duguay, M., Bonizzato, M., Delivet-Mongrain, H., Fortier-Lebel, N., & Martinez, M. (2023) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2023.102492 · Cited by 15

AMPA receptors play an important role in the biological consequences of spinal cord injury: Implications for AMPA receptor modulators for therapeutic benefit

Witkin, J. M., Radin, D. P., Rana, S. D., Fuller, D. D., Fusco, A. F., Demers, J. C., Thakre, P. P., Smith, J. L., LIPPA, A. S., & Cerne, R. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116302 · Cited by 13

Hindlimb Somatosensory Information Influences Trunk Sensory and Motor Cortices to Support Trunk Stabilization

Nandakumar, B., Blumenthal, G. H., Pauzin, F. P., & Moxon, K. A. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab150 · Cited by 16

A Single Cell Atlas of Spared Tissue Below a Spinal Cord Injury Reveals Cellular Mechanisms of RepairPreprint

Matson, K. J. E., Russ, D. E., Kathe, C., Maric, D., Hua, I., Krynitsky, J., Pursley, R. H., Sathyamurthy, A., Squair, J. W., Courtine, G., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.28.441862 · Cited by 13

Combined neuromodulatory approaches in the central nervous system for treatment of spinal cord injury

Noga, B. R., & Guest, J. D. (2021) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000999 · Cited by 14

Spinal cord stimulation for spinal cord injury – Where do we stand? A narrative review

Mundra, A., Kalidindi, K. K. V., Chhabra, H. S., & Manghwani, J. (2023) · Journal of Clinical Orthopaedics and Trauma · doi:10.1016/j.jcot.2023.102210 · Cited by 14

A Pragmatic Review on Spinal Cord Stimulation Therapy for Parkinson's Disease Gait Related Disorders: Gaps and Controversies

Hvingelby, V. S., Carra, R. B., Terkelsen, M. H., Hamani, C., Capato, T., Košutzká, Z., Krauss, J. K., Moro, E., Pavese, N., & Cury, R. G. (2024) · Movement Disorders Clinical Practice · doi:10.1002/mdc3.14143 · Cited by 12

Machine learning classifies predictive kinematic features in a mouse model of neurodegeneration

Huang, R., Nikooyan, A. A., Xu, B., Joseph, M. S., Damavandi, H. G., von Trotha, N., Li, L., Bhattarai, A., Zadeh, D., Seo, Y., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-82694-3 · Cited by 13

Targeting Central Nervous System Regeneration with Cell Type Specificity

Anderson, M. A. (2021) · Neurosurgery Clinics of North America · doi:10.1016/j.nec.2021.03.011 · Cited by 12

Innovations in Electrical Stimulation Harness Neural Plasticity to Restore Motor Function

Peng, X., Hickman, J. L., Bowles, S. G., Donegan, D., & Welle, C. G. (2018) · Bioelectronics in Medicine · doi:10.2217/bem-2019-0002 · Cited by 13

Mapping the corticoreticular pathway from cortex‐wide anterograde axonal tracing in the mouse

Boyne, P., Awosika, O. O., & Luo, Y. (2021) · Journal of Neuroscience Research · doi:10.1002/jnr.24975 · Cited by 11

Effect of corticospinal and reticulospinal tract damage on spastic muscle tone and mobility: a retrospective observational MRI study

Schading‐Sassenhausen, S., Dietz, V., & Freund, P. (2025) · EBioMedicine · doi:10.1016/j.ebiom.2025.105824 · Cited by 12

A neuronal architecture underlying autonomic dysreflexia

Soriano, J. E., Hudelle, R., Mahe, L., Gautier, M., Teo, A. Y. Y., Skinnider, M. A., Laskaratos, A., Ceto, S., Kathe, C., Hutson, T. H., et al. (2025) · Nature · doi:10.1038/s41586-025-09487-w · Cited by 14

Modular organization of locomotor networks in people with severe spinal cord injury

Sun, S. Y., Giszter, S. F., Harkema, S. J., & Angeli, C. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1041015 · Cited by 10

Do Pharmacological Treatments Act in Collaboration with Rehabilitation in Spinal Cord Injury Treatment? A Review of Preclinical Studies

Tashiro, S., Shibata, S., Nagoshi, N., Zhang, L., Yamada, S., Tsuji, T., Nakamura, M., & Okano, H. (2024) · Cells · doi:10.3390/cells13050412 · Cited by 10

Wireless Epidural Electrical Stimulation in Combination With Serotonin Agonists Improves Intraspinal Metabolism in Spinal Cord Injury Rats

Yao, Q., Guan, J., Ma, L., Cheng, L., Duan, F., Xu, F., Zhao, W., Duan, W., Wu, H., Chen, Z., et al. (2020) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.13344 · Cited by 10

Double viral vector intersectional approaches for pathway-selective manipulation of motor functions and compensatory mechanisms

Isa, T. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113959 · Cited by 9

Collagen I is a critical organizer of scarring and CNS regeneration failurePreprint

Bi, Y., Duan, W., & Silver, J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.07.592424 · Cited by 11

A fresh look at propriospinal interneurons plasticity and intraspinal circuits remodeling after spinal cord injury

Cheng, J., & Guan, N. N. (2023) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2023.04.001 · Cited by 9

Spinal cord injury repair based on drug and cell delivery: From remodeling microenvironment to relay connection formation

Ma, W., & Li, X. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.101556 · Cited by 10

Spinal cord ultrasound stimulation modulates corticospinal excitability in humans

Hou, L., & Lei, Y. (2025) · Brain stimulation · doi:10.1016/j.brs.2025.05.134 · Cited by 10

Advances in Neuromodulation and Digital Brain–Spinal Cord Interfaces for Spinal Cord Injury

Jaszczuk, P., Bratelj, D., Capone, C., Rudnick, M., Pötzel, T., Verma, R. K., & Fiechter, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26136021 · Cited by 11

Characterization of interlimb interaction via transcutaneous spinal stimulation of cervical and lumbar spinal enlargements

Atkinson, D. A., Steele, A. G., Manson, G. A., Sheynin, J., Oh, J., Gerasimenko, Y., & Sayenko, D. G. (2022) · Journal of Neurophysiology · doi:10.1152/jn.00456.2021 · Cited by 9

Exercise therapy guides cortical reorganization after midthoracic spinal contusion to enhance control of lower thoracic muscles, supporting functional recovery

Nandakumar, B., Blumenthal, G. H., Disse, G. D., Desmond, P. C., Ebinu, J. O., Ricard, J., Bethea, J. R., & Moxon, K. A. (2023) · Experimental Neurology · doi:10.1016/j.expneurol.2023.114394 · Cited by 9

Neural Ensemble Dynamics in Trunk and Hindlimb Sensorimotor Cortex Encode for the Control of Postural Stability

Disse, G. D., Nandakumar, B., Pauzin, F. P., Blumenthal, G. H., Kong, Z., Ditterich, J., & Moxon, K. A. (2022) · Cell Reports · doi:10.1016/j.celrep.2023.112347 · Cited by 12

Integrative analysis reveals a four-gene signature for predicting survival and immunotherapy response in colon cancer patients using bulk and single-cell RNA-seq data

Chai, R., Zhao, Y., Su, Z., & Liang, W. H. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1277084 · Cited by 9

Intensity of Intraoperative Spinal Cord Hyperechogenicity as a Novel Potential Predictive Indicator of Neurological Recovery for Degenerative Cervical Myelopathy

Chen, G., Wei, F., Li, J., Shi, L., Zhang, W., Wang, X., Xu, Z., Liu, X., Zou, X., & Liu, S. (2021) · Korean Journal of Radiology · doi:10.3348/kjr.2020.0755 · Cited by 9

Anti-Chondroitin Sulfate Proteoglycan Strategies in Spinal Cord Injury: Temporal and Spatial Considerations Explain the Balance between Neuroplasticity and Neuroprotection

Hryciw, T., Geremia, N. M., Walker, M. A., Xu, X., & Brown, A. M. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2018.5928 · Cited by 9

Effects of transcranial magnetic stimulation on axonal regeneration in the corticospinal tract of female rats with spinal cord injury

Hu, M., Tang, Z., Li, H., Lei, Q., Xu, Q., Su, J., Huang, Y., Chen, S., & Chen, H. (2024) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2024.110267 · Cited by 8

Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats

Zaforas, M., Benayas, E., Madroñero-Mariscal, R., Domínguez-Bajo, A., Fernández‐López, E., Hernández-Martín, Y., González‐Mayorga, A., Alonso‐Calviño, E., Hernandez, E. R., López‐Dolado, E., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.12.031 · Cited by 8

Mapping reticulospinal drive across various muscles of the upper and lower extremities

Eilfort, A. M., Neumann, L., & Filli, L. (2025) · Experimental Physiology · doi:10.1113/ep092763 · Cited by 9

Recent advances in potential mechanisms of epidural spinal cord stimulation for movement disorders

Zhang, T., Jia, Y., Wang, N., Chai, X., He, Q., Cao, T., Mu, Q., Lan, Q., Zhao, J., & Yang, Y. (2025) · Experimental Neurology · doi:10.1016/j.expneurol.2025.115330 · Cited by 8

Genetic control of neuronal activity enhances axonal growth only on permissive substrates

Mesquida-Veny, F., Martínez‐Torres, S., del Rı́o, J. A., & Hervera, A. (2022) · Molecular Medicine · doi:10.1186/s10020-022-00524-2 · Cited by 8

Spinal Cord Stimulation to Enable Leg Motor Control and Walking in People with Spinal Cord Injury

Seáñez, I., Capogrosso, M., Minassian, K., & Wagner, F. B. (2022) · Springer eBooks · doi:10.1007/978-3-031-08995-4_18 · Cited by 8

Exploring propriospinal neuron-mediated neural circuit plasticity using recombinant viruses after spinal cord injury

Deng, L., Ravenscraft, B., & Xu, X. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113962 · Cited by 8

Intraspinal Administration of Netrin-1 Promotes Locomotor Recovery after Complete Spinal Cord Transection

Quintá, H. R. (2021) · Journal of Neurotrauma · doi:10.1089/neu.2020.7571 · Cited by 8

Widening spinal injury research to consider all supraspinal cell types: Why we must and how we can

Blackmore, M. G., Batsel, E., & Tsoulfas, P. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113862 · Cited by 8

A Silver Lining of Neuropathic Pain: Predicting Favorable Functional Outcome in Spinal Cord Injury

Xu, M.-L., Wu, X.-B., Liang, Y., Li, N., Hu, X., Lin, X., Sun, M.-Q., Dai, C., Niu, D., Zhang, Y.-R., et al. (2023) · Journal of Pain Research · doi:10.2147/jpr.s414638 · Cited by 7

Epidural electrical stimulation combined with photobiomodulation restores hindlimb motor function in rats with thoracic spinal cord injury

Guo, X.-J., He, L., Chang, J.-Q., Su, W.-N., Feng, T., Gao, Y., Wu, Y., Zhao, C., & Rao, J. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.115112 · Cited by 7

Combining therapeutic strategies with rehabilitation improves motor recovery in animal models of spinal cord injury: A systematic review and meta-analysis

Zhang, L., Yamada, S., Nagoshi, N., Shinozaki, M., Tsuji, T., Nakamura, M., Okano, H., & Tashiro, S. (2025) · Annals of Physical and Rehabilitation Medicine · doi:10.1016/j.rehab.2024.101911 · Cited by 7

Spinal cord regeneration: A brief overview of the present scenario and a sneak peek into the future

Srivastava, E., Singh, A., & Kumar, A. (2021) · Biotechnology Journal · doi:10.1002/biot.202100167 · Cited by 8

An integrated long-acting implant of clinical safe cells, drug and biomaterials effectively promotes spinal cord repair and restores motor functions

Li, L., Mu, J., Chen, J., Huang, T., Zhang, Y., Cai, Y., Zhang, T., Kong, X., Sun, J., Jiang, X., et al. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.09.010 · Cited by 7

Introducing a biomimetic coating for graphene neuroelectronics: toward in-vivo applications

Bourrier, A., Szarpak, A., Veliev, F., Renato, O.-H., Shkorbatova, P. Y., Bonizzato, M., Rey, E., Barraud, Q., Briançon‐Marjollet, A., Auzély‐Velty, R., et al. (2019) · Biomedical Physics & Engineering Express · doi:10.1088/2057-1976/ab42d6 · Cited by 7

Anatomical Plasticity of Rostrally Terminating Axons as a Possible Bridging Substrate across a Spinal Injury

Doperalski, A. E., Montgomery, L. R., Mondello, S. E., & Howland, D. R. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2018.6193 · Cited by 7

Effects of a contusive spinal cord injury on cortically-evoked spinal spiking activity in rats

Borrell, J. A., Krizsan‐Agbas, D., Nudo, R. J., & Frost, S. B. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abc1b5 · Cited by 6

Restoration of Direct Corticospinal Communication Across Sites of Spinal InjuryPreprint

Jayaprakash, N., Nowak, D. J., Eastwood, E., Krueger, N., Wang, Z., & Blackmore, M. G. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/546374 · Cited by 7

Reclaiming Hand Functions for Chronic Spinal Cord Injury with Epidural Brain-Computer InterfacePreprint

Liu, D., Shan, Y., Chen, L., Li, W., Yao, X., Yao, R., Zheng, J., Liang, F., Zhu, W., Xu, H., et al. (2024) · medRxiv · doi:10.1101/2024.09.05.24313041 · Cited by 10

Functional synaptic connectivity of engrafted spinal cord neurons with hindlimb motor circuitry in the injured spinal cord

Tucker, A., Baltazar, A., Eisdorfer, J. T., Thackray, J. K., Vo, K., Thomas, H., Tandon, A., Moses, J., Singletary, B., Gillespie, T., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-65395-7 · Cited by 6

Perilesional neuromodulation replaces lost sensorimotor function in persons with spinal cord injury

Calvert, J. S., Parker, S. R., Govindarajan, L. N., Darie, R., Shaaya, E. A., Solinsky, R. J., Valle, L. M. D., Miranda, P., Jang, J., Tiwari, E., et al. (2026) · Nature Biomedical Engineering · doi:10.1038/s41551-026-01627-5 · Cited by 6

A narrative review of motor control dual pathways: the corticospinal and reticulospinal tracts in synergy and differentiation

Xing, Y., Liu, J., Wu, L., Zhang, K., & Yang, S. L. (2026) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2026.1768036 · Cited by 6

Evidence for reticulospinal plasticity underlying motor recovery in Brown-Séquard-plus Syndrome: a case report

Eilfort, A. M., Rasenack, M., Zörner, B., Curt, A. E. P., & Filli, L. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1335795 · Cited by 6

Trunk Neuromuscular Impairment Following Spinal Cord Injury: Insights into Bidirectional and Nonlinear Corticomuscular Coupling

Shan, M., Wang, Z., Gao, Y., Xie, H., Niu, W., & Zhang, M. (2025) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2025.3587074 · Cited by 7

Highlights from the 30th Annual Meeting of the Society for the Neural Control of Movement

Russo, M., Ozeri-Engelhard, N., Hupfeld, K. E., Nettekoven, C., Thibault, S., Sedaghat-Nejad, E., Buchwald, D., Xing, D., Zobeiri, O. A., Kilteni, K., et al. (2021) · Journal of Neurophysiology · doi:10.1152/jn.00334.2021 · Cited by 6

Neuroregeneration Improved by Sodium-D,L-Beta-Hydroxybutyrate in Primary Neuronal Cultures

Ari, C., D’Agostino, D. P., & Cha, B. J. (2024) · Pharmaceuticals · doi:10.3390/ph17091160 · Cited by 6

Estimating upper-extremity function from kinematics in stroke patients following goal-oriented computer-based training

Ballester, B. R., Antenucci, F., Maier, M., Coolen, A. C. C., & Verschure, P. F. M. J. (2021) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-021-00971-8 · Cited by 6

3D imaging of supraspinal inputs to the thoracic and lumbar spinal cord mapped by retrograde tracing and light‐sheet microscopy

Lu, T., Shinozaki, M., Nagoshi, N., Nakamura, M., & Okano, H. (2022) · Journal of Neurochemistry · doi:10.1111/jnc.15653 · Cited by 6

Formation of a novel supraspinal-spinal connectome that relearns the same motor task after complete paralysis

Urban, L. S., Thornton, M. A., Dixie, K. L. I., Dale, E. A., Zhong, H., Phelps, P. E., Burdick, J. W., & Edgerton, V. R. (2021) · Journal of Neurophysiology · doi:10.1152/jn.00422.2020 · Cited by 6

Changes in synaptic inputs to dI3 INs and MNs after complete transection in adult mice

Goltash, S., Stevens, S. J., Topcu, E., & Bui, T. V. (2023) · Frontiers in Neural Circuits · doi:10.3389/fncir.2023.1176310 · Cited by 5

Electrical stimulation of the cuneiform nucleus enhances the effects of rehabilitative training on locomotor recovery after incomplete spinal cord injury

Scheuber, M. I., Guidolin, C., Martins, S. R., Sartori, A. M., Hofer, A., & Schwab, M. E. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1352742 · Cited by 5

Potential Roles of Specific Subclasses of Premotor Interneurons in Spinal Cord Function Recovery after Traumatic Spinal Cord Injury in Adults

Dominguez, A. L., & Clotman, F. (2024) · Cells · doi:10.3390/cells13080652 · Cited by 5

Magnetic Stimulation of Gigantocellular Reticular Nucleus with Iron Oxide Nanoparticles Combined Treadmill Training Enhanced Locomotor Recovery by Reorganizing Cortico-Reticulo-Spinal Circuit

Li, J., Zhou, T., Wang, P., Yin, R., Zhang, S., Cao, Y., Zong, L., Xiao, M., Zhang, Y., Liu, W., et al. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s464498 · Cited by 5

DBS in the restoration of motor functional recovery following spinal cord injury

Li, W., Qu, W., Li, Y., Wang, S., Liu, D., Deng, L., & Wang, Y. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1442281 · Cited by 5

Corticolumbar dynamics during recovery after spinal cord injury

Anil, S. (2020) · Infoscience (Ecole Polytechnique Fédérale de Lausanne) · doi:10.5075/epfl-thesis-9816

Use-dependent reorganization of spared and severed descending pathways after contusion SCI in rats

NGUYEN, A. (2014) · IRIS

Cortico-reticulo-spinal circuits mediate functional recovery after spinal cord contusion

Asboth, L. (2017) · Infoscience (Ecole Polytechnique Fédérale de Lausanne) · doi:10.5075/epfl-thesis-7983

Brain-controlled modulation of spinal circuits improves recovery from spinal cord injury

Bonizzato, M., Pidpruzhnykova, G., DiGiovanna, J., Shkorbatova, P., Pavlova, N., Micera, S., & Courtine, G. (2018) · Nature Communications · doi:10.1038/s41467-018-05282-6 · Cited by 149

Restoring Voluntary Control of Locomotion after Paralyzing Spinal Cord Injury

van den Brand, R., Heutschi, J., Barraud, Q., DiGiovanna, J., Bartholdi, K., Huerlimann, M., Friedli, L., Vollenweider, I., Moraud, E. M., Duis, S., et al. (2012) · Science · doi:10.1126/science.1217416 · Cited by 767