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Animal models of neurodegenerative diseases
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Animal models of adult-onset neurodegenerative diseases have enhanced the understanding of the molecular pathogenesis of Alzheimer's disease, Parkinson's disease, frontotemporal dementia, and amyotrophic lateral sclerosis. Nevertheless, our understanding of these disorders and the development of mechanistically designed therapeutics can still benefit from more rigorous use of the models and from generation of animals that more faithfully recapitulate human disease. Here we review the current state of rodent models for Alzheimer's disease, Parkinson's disease, frontotemporal dementia, and amyotrophic lateral sclerosis. We discuss the limitations and utility of current models, issues regarding translatability, and future directions for developing animal models of these human disorders.
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“It typically requires additional expression of human tau harboring mutations associated with primary tauopathy (94–96) or seeding mutant human APP knock-in mouse brain with human AD brain-derived tau (97) to develop the tau pathology.”
From Modeling late-onset Alzheimer’s disease neuropathology via direct neuronal reprogramming (2024) · cites this paper as [94]
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1 retracted
Winton, M. J., Lee, E. B., Sun, E., Wong, M. M., Leight, S., Zhang, B., Trojanowski, J., & Lee, V. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6637-10.2011 · Cited by 110
RetractedAmyloid oligomers exacerbate tau pathology in a mouse model of tauopathy
Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359
Spillantini, M. G., Schmidt, M. L., Lee, V. M.-Y., Trojanowski, J. Q., Jakes, R., & Goedert, M. (1997) · Nature · doi:10.1038/42166 · Cited by 8,382
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
Neumann, M., Sampathu, D. M., Kwong, L. K., Truax, A. C., Micsenyi, M. C., Chou, T. T., Bruce, J., Schuck, T., Grossman, M., Clark, C. M., et al. (2006) · Science · doi:10.1126/science.1134108 · Cited by 6,576
Prusiner, S. B. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.23.13363 · Cited by 5,373
DeJesus-Hernandez, M., Mackenzie, I. R., Boeve, B. F., Boxer, A. L., Baker, M., Rutherford, N. J., Nicholson, A. M., Finch, N. A., Flynn, H., Adamson, J., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.011 · Cited by 4,936 · cited 1×
“Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.”
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Renton, A. E., Majounie, E., Waite, A., Simón-Sánchez, J., Rollinson, S., Gibbs, J. R., Schymick, J. C., Laaksovirta, H., van Swieten, J. C., Myllykangas, L., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.010 · Cited by 4,409
Meta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease
(EADI), E. A. D. I., Lambert, J.-C., (GERAD), G. A. E. R. I. A. D., Alzheimer's Disease Genetic Consortium (ADGC), (CHARGE), C. F. H. A. A. R. I. G. E., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., et al. (2013) · Nature Genetics · doi:10.1038/ng.2802 · Cited by 4,336
Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation
Gurney, M. E., Pu, H., Chiu, A. Y., Dal Canto, M. C., Polchow, C. Y., Alexander, D. D., Caliendo, J., Hentati, A., Kwon, Y. W., Deng, H.-X., et al. (1994) · Science · doi:10.1126/science.8209258 · Cited by 4,143
Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles
Oddo, S., Caccamo, A., Shepherd, J. D., Murphy, M. P., Golde, T. E., Kayed, R., Metherate, R., Mattson, M. P., Akbari, Y., & LaFerla, F. M. (2003) · Neuron · doi:10.1016/s0896-6273(03)00434-3 · Cited by 4,126
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Börü, Ü. T., Saritas, Z. K., GÖRÜCÜ, F., Bölük, C., Acar, H., Koç, Y., & Demiral, G. Z. (2024) · Brain Research · doi:10.1016/j.brainres.2024.148842 · Cited by 3
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Ceisel, A., Graziano, G., Emmerich, K., Shi, X., Kam, T., Flores‐Bellver, M., Vergara, M. N., Aparicio‐Domingo, S., Brenerman, B. M., Vielle, A., et al. (2026) · Disease Models & Mechanisms · doi:10.1242/dmm.052747 · Cited by 2
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Paramshetti, S., Angolkar, M., Patil, D., Spandana, K. M. A., Hani, U., & Osmani, R. A. M. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-28822-7.00009-x · Cited by 2
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Khan, H. Y., Khan, Y. H., Hassan, M. N., Ahmad, A., Khan, R. H., & Arjmand, F. (2025) · Biophysical Chemistry · doi:10.1016/j.bpc.2025.107493 · Cited by 1
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Jalnapurkar, B., Le, D., Shainin, W., Zarcone, R., Bhatnagar, R., Chin, J., Corbin, C. K., Curt, C., Hodge, B. A., Martinez, F., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.21.568079 · Cited by 1
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Ji, Y., Mandal, P., Liu, J., Hu, W., Colon, B. D., Wan, C., Pan, R. W., Guo, D., Zhang, L., Gu, X., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.06.736894 · Cited by 1
Gong, J. (2020) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-8039
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Alimohammadi, E., Nikzad, A., Khedri, M., Rezaeian, M., Jahromi, A. M., Rezaei, N., & Maleki, R. (2020) · Research Square · doi:10.21203/rs.3.rs-45640/v1
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Uggerud, I. M., Kråkenes, T., Hirai, H., Vedeler, C. A., & Schubert, M. (2022) · Research Square · doi:10.21203/rs.3.rs-1166640/v1
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Uggerud, I. M., Kråkenes, T., Hirai, H., Vedeler, C. A., & Schubert, M. (2022) · Research Square · doi:10.21203/rs.3.rs-1505572/v1
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Metadata
- Authors
- Dawson, T. M., Golde, T. E., & Lagier-Tourenne, C.
- Affiliations
- Johns Hopkins University (US)
- University of Florida (US)
- Corresponding author
- Dawson, Ted M.
- Golde, Todd E.
- Venue
- Nature Neuroscience
- Published
- 2018-09-24
- Volume
- 21
- Issue
- 10
- Pages
- 1370-1379
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- PMC
- PMC6615039
- OpenAlex
- W2891411797
- Cited by
- 576
- References
- 151
- Citations by year
- 2026: 59 · 2025: 73 · 2024: 89 · 2023: 72 · 2022: 88 · 2021: 79 · 2020: 70 · 2019: 41 · 2018: 4
- FWCI
- 6.37
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (R01AG018454, U01AG046139, P50AG047266)
- National Cancer Institute (P01CA166009)
- National Institute of Neurological Disorders and Stroke (R21NS098006, R01NS087227, R01NS082205, P50NS038377)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
- Health Sciences › Medicine › Clinical Neurology › Amyotrophic Lateral Sclerosis Research
- Keywords
- animal models, neurodegenerative diseases, Alzheimer's disease, Parkinson's disease, frontotemporal dementia, amyotrophic lateral sclerosis, rodent models, translatability, disease modeling
- MeSH terms
- Animals, Disease Models, Animal, Humans, Neurodegenerative Diseases
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