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Anticancer Activity of Erianin: Cancer-Specific Target Prediction Based on Network Pharmacology

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Aminopeptidase N‐Responsive Conjugates with Tunable Charge‐Reversal Properties for Highly Efficient Tumor Accumulation and Penetration

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PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C

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Hypoxic microenvironment induced spatial transcriptome changes in pancreatic cancer

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Multi-Omics Analysis of Fatty Acid Metabolism in Thyroid Carcinoma

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miR-194-5p down-regulates tumor cell PD-L1 expression and promotes anti-tumor immunity in pancreatic cancer

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NF-κB and TET2 promote macrophage reprogramming in hypoxia that overrides the immunosuppressive effects of the tumor microenvironment

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E3 ubiquitin ligase DTX2 fosters ferroptosis resistance via suppressing NCOA4-mediated ferritinophagy in non-small cell lung cancer

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Transcriptional Repression of Ferritin Light Chain Increases Ferroptosis Sensitivity in Lung Adenocarcinoma

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SQLE, A Key Enzyme in Cholesterol Metabolism, Correlates With Tumor Immune Infiltration and Immunotherapy Outcome of Pancreatic Adenocarcinoma

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Comprehensive Integrative Analysis Reveals the Association of KLF4 with Macrophage Infiltration and Polarization in Lung Cancer Microenvironment

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Identification of ACSL4 as a biomarker and contributor of ferroptosis in clear cell renal cell carcinoma

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MXD3 as an onco-immunological biomarker encompassing the tumor microenvironment, disease staging, prognoses, and therapeutic responses in multiple cancer types

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TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer

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Combination Effect of Novel Bimetallic Ag-Ni Nanoparticles with Fluconazole against Candida albicans

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p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP

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TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-3

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Colorectal cancer tumor cell-derived exosomal miR-203a-3p promotes CRC metastasis by targeting PTEN-induced macrophage polarization

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IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling

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A multi-omic dissection of super-enhancer driven oncogenic gene expression programs in ovarian cancer

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Zinc transporter SLC39A13/ZIP13 facilitates the metastasis of human ovarian cancer cells via activating Src/FAK signaling pathway

Cheng, X., Wang, J., Liu, C., Jiang, T., Yang, N., Liu, D., Zhao, H., & Xu, Z. (2021) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-021-01999-3 · Cited by 39 · see citing works

Spatial Mapping and Immunomodulatory Role of the OX40/OX40L Pathway in Human Non–Small Cell Lung Cancer

Porciuncula, A., Morgado, M., Gupta, R., Syrigos, K., Meehan, R., Zacharek, S. J., Frederick, J. P., & Schalper, K. A. (2021) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-21-0987 · Cited by 39 · see citing works

Hepcidin Downregulation Correlates With Disease Aggressiveness And Immune Infiltration in Liver Cancers

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Pan-cancer analysis combined with experiments predicts CTHRC1 as a therapeutic target for human cancers

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Estrogen Receptor 1 Inhibition of Wnt/β-Catenin Signaling Contributes to Sex Differences in Hepatocarcinogenesis

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SBSN drives bladder cancer metastasis via EGFR/SRC/STAT3 signalling

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Non-coding RNAs targeting notch signaling pathway in cancer: From proliferation to cancer therapy resistance

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MacroH2A impedes metastatic growth by enforcing a discrete dormancy program in disseminated cancer cells

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TRAIL promotes the polarization of human macrophages toward a proinflammatory M1 phenotype and is associated with increased survival in cancer patients with high tumor macrophage content

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A 13-Gene Metabolic Prognostic Signature Is Associated With Clinical and Immune Features in Stomach Adenocarcinoma

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CFIm-mediated alternative polyadenylation remodels cellular signaling and miRNA biogenesis

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Analysis of estrogen-regulated enhancer RNAs identifies a functional motif required for enhancer assembly and gene expression

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Integrative Analysis of MUC4 to Prognosis and Immune Infiltration in Pan-Cancer: Friend or Foe?

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Elevated MMP10/13 mediated barrier disruption and NF-κB activation aggravate colitis and colon tumorigenesis in both individual or full miR-148/152 family knockout mice

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MiR-93-5p regulates tumorigenesis and tumor immunity by targeting PD-L1/CCND1 in breast cancer

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Deep learning-based prediction of molecular cancer biomarkers from tissue slides: A new tool for precision oncology

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SEMA3C Supports Pancreatic Cancer Progression by Regulating the Autophagy Process and Tumor Immune Microenvironment

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High expression of S100A2 predicts poor prognosis in patients with endometrial carcinoma

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cSurvival: a web resource for biomarker interactions in cancer outcomes and in cell lines

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Transmembrane protein TMEM119 facilitates the stemness of breast cancer cells by activating Wnt/β-catenin pathway

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Evaluation of Ferroptosis-related Gene AKR1C1 as a Novel Biomarker Associated with the Immune Microenvironment and Prognosis in Breast Cancer

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The Multi-Omics Analysis of Key Genes Regulating EGFR-TKI Resistance, Immune Infiltration, SCLC Transformation in EGFR-Mutant NSCLC

Wang, Z., Zhang, L., Xu, W., Li, J., Liu, Y., Zeng, X., Zhong, M., & Zhu, Y. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s341001 · Cited by 32 · see citing works

Long-read sequencing reveals oncogenic mechanism of HPV-human fusion transcripts in cervical cancer

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Development of a Novel Immune Infiltration-Based Gene Signature to Predict Prognosis and Immunotherapy Response of Patients With Cervical Cancer

Yu, S., Li, X., Zhang, J., & Wu, S. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.709493 · Cited by 31 · see citing works

TRPV2 Promotes Cell Migration and Invasion in Gastric Cancer via the Transforming Growth Factor-β Signaling Pathway

Kato, S., Shiozaki, A., Kudou, M., Shimizu, H., Kosuga, T., Ohashi, T., Arita, T., Konishi, H., Komatsu, S., Kubota, T., et al. (2021) · Annals of Surgical Oncology · doi:10.1245/s10434-021-11132-5 · Cited by 31 · see citing works

Comprehensive Pan-Cancer Genomic Analysis Reveals PHF19 as a Carcinogenic Indicator Related to Immune Infiltration and Prognosis of Hepatocellular Carcinoma

Zhu, Z., Tang, N., Wang, M.-F., Zhou, J., Wang, J., Ren, H., & Shi, X. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2021.781087 · Cited by 31 · see citing works

miR-16-5p regulates aerobic glycolysis and tumorigenesis of NSCLC cells via LDH-A/lactate/NF-κB signaling

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METTL3 and STAT3 form a positive feedback loop to promote cell metastasis in hepatocellular carcinoma

Liu, B., Cao, J., Wu, B., Hao, K., Wang, X., Chen, X., & Shen, Z. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01148-7 · Cited by 30 · see citing works

Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma

Graziano, V., Dannhorn, A., Hulme, H., Williamson, K., Buckley, H., Karim, S. A., Wilson, M., Lee, S. Y., Kaistha, B. P., Islam, S., et al. (2023) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2022-006457 · Cited by 29 · see citing works

Comprehensive Analysis of Monocarboxylate Transporter 4 (MCT4) expression in breast cancer prognosis and immune infiltration via integrated bioinformatics analysis

Yuan, C., Zhang, J., Lou, J., Wang, S., Jiang, Y., Wu, F., & Wang, S. (2021) · Bioengineered · doi:10.1080/21655979.2021.1951928 · Cited by 30 · see citing works

Prognostic Neurotransmitter Receptors Genes Are Associated with Immune Response, Inflammation and Cancer Hallmarks in Brain Tumors

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A cancer-associated RNA polymerase III identity drives robust transcription and expression of snaR-A noncoding RNA

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Bioinformatics analysis of the role of aldolase A in tumor prognosis and immunity

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Lower expression of NINJ1 (Ninjurin 1), a mediator of plasma membrane rupture, is associated with advanced disease and worse prognosis in serous ovarian cancer

Berkel, Ç., & Çaçan, E. (2022) · Immunologic Research · doi:10.1007/s12026-022-09323-7 · Cited by 30 · see citing works

μ‐opioid receptor agonist facilitates circulating tumor cell formation in bladder cancer via the MOR/AKT/Slug pathway: a comprehensive study including randomized controlled trial

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Musashi–1—A Stemness RBP for Cancer Therapy?

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E2F3 drives the epithelial-to-mesenchymal transition, cell invasion, and metastasis in breast cancer

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A gene set enrichment analysis for cancer hallmarks

Menyhárt, O., Kothalawala, W. J., & Győrffy, B. (2024) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2024.101065 · Cited by 92 · see citing works

Abstract 3546: Putting genes in context by linking gene signatures to established cancer hallmarks

Menyhárt, O., Kothalawala, W. J., & Győrffy, B. (2024) · Cancer Research · doi:10.1158/1538-7445.am2024-3546

CancerHallmarks.com: A tool for the enrichment analysis of the cancer hallmarks.

Győrffy, B., Menyhárt, O., Kothalawala, W. J., & Santarpia, L. (2024) · Journal of Clinical Oncology · doi:10.1200/jco.2024.42.16_suppl.e15079

A pan-cancer analysis of prognostic genes

Anaya, J., Reon, B. J., Chen, W., Bekiranov, S., & Dutta, A. (2016) · PeerJ · doi:10.7717/peerj.1499 · Cited by 63 · see citing works

Abstract P5-04-21: Decoding breast cancer: unveiling the role of hallmark genes in tumor progression and prognosis

Győrffy, B., Menyhárt, O., & Kothalawala, W. J. (2025) · Clinical Cancer Research · doi:10.1158/1557-3265.sabcs24-p5-04-21