The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion
Open accessAbstract
Tumour necrosis factor-alpha (TNF-alpha) is an important inflammatory factor that acts as a master switch in establishing an intricate link between inflammation and cancer. A wide variety of evidence has pointed to a critical role of TNF-alpha in tumour proliferation, migration, invasion and angiogenesis. The function of TNF-alpha as a key regulator of the tumour microenvironment is well recognised. We will emphasise the contribution of TNF-alpha and the nuclear factor-kappaB pathway on tumour cell invasion and metastasis. Understanding the mechanisms underlying inflammation-mediated metastasis will reveal new therapeutic targets for cancer prevention and treatment.
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Cites
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Signalling pathways of the TNF superfamily: a double-edged sword
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The snail superfamily of zinc-finger transcription factors
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IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer
Gyrd-Hansen, M., & Meier, P. (2010) · Nature Reviews Cancer · doi:10.1038/nrc2889 · Cited by 790
Cell-cell communication: New insights and clinical implications
Su, J., Song, Y., Zhu, Z., Huang, X., Fan, J., Qiao, J., & Mao, F. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01888-z · Cited by 433
Myles, I. A., Castillo, C. R., Barbian, K. D., Kanakabandi, K., Virtaneva, K., Fitzmeyer, E., Paneru, M., Otaizo-Carrasquero, F., Myers, T. G., Markowitz, T. E., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aaz8631 · Cited by 139
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NFκB/p53 crosstalk—a promising new therapeutic target
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Targeting signaling pathways in multiple myeloma: Pathogenesis and implication for treatments
Hu, J., & Hu, W.-X. (2018) · Cancer Letters · doi:10.1016/j.canlet.2017.11.020 · Cited by 84
Zoppi, N., Chiarelli, N., Binetti, S., Ritelli, M., & Colombi, M. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.01.005 · Cited by 49
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Exploring and bypassing resistance to targeted therapies in colorectal cancer
Favier, S., Xiong, W., Chalabi-Dchar, M., Chettab, K., Piercey, O., Wu, T., Fenouil, T., Albaret, M.-A., Jordheim, L. P., Diaz, J.-J., et al. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118741 · Cited by 12
Metadata
- Authors
- Wu, Y., & Zhou, B. P.
- Venue
- British Journal of Cancer
- Published
- 2010-01-19
- Volume
- 102
- Issue
- 4
- Pages
- 639-644
- ISSN
- 0007-0920 (ISSN-L)
- 1532-1827
- OpenAlex
- W1983074899
- Cited by
- 798
- References
- 6
- FWCI
- 11.20
- Type
- journal article
- Language
- en
- Open access
- hybrid
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