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The gut flora as a forgotten organ
Open accessAbstract
The intestinal microflora is a positive health asset that crucially influences the normal structural and functional development of the mucosal immune system. Mucosal immune responses to resident intestinal microflora require precise control and an immunosensory capacity for distinguishing commensal from pathogenic bacteria. In genetically susceptible individuals, some components of the flora can become a liability and contribute to the pathogenesis of various intestinal disorders, including inflammatory bowel diseases. It follows that manipulation of the flora to enhance the beneficial components represents a promising therapeutic strategy. The flora has a collective metabolic activity equal to a virtual organ within an organ, and the mechanisms underlying the conditioning influence of the bacteria on mucosal homeostasis and immune responses are beginning to be unravelled. An improved understanding of this hidden organ will reveal secrets that are relevant to human health and to several infectious, inflammatory and neoplastic disease processes.
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“In the absence of the resident microbiota, members of the TLR family have low or absent expression profiles in the gut, thus compromising appropriate neuroendocrine responses to pathogenic threats (O'Hara and Shanahan, 2006).”
From The Microbiota-Gut-Brain Axis (2019) · cites this paper as O'Hara and Shanahan, 2006
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“Microbial abundance and community structure in the proximal intestine is affected by gastric acid, pancreaticobiliary secretions, and fast transit45.”
From The gut Microbiome in adult and pediatric functional gastrointestinal disorders (2019) · cites this paper as [45]
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“Studies have since shown that gut bacteria play a vital role in regulating important aspects of brain development and function, along with other host physiology [5, 7].”
From Effect of fecal microbiota transplant on symptoms of psychiatric disorders: a systematic review (2020) · cites this paper as [5]
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Diversity of the Human Intestinal Microbial Flora
Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913
The gut microbiota as an environmental factor that regulates fat storage
Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., & Gordon, J. I. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407076101 · Cited by 6,245
Obesity alters gut microbial ecology
Ley, R. E., Bäckhed, F., Turnbaugh, P., Lozupone, C. A., Knight, R. D., & Gordon, J. I. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504978102 · Cited by 6,176
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004) · Cell · doi:10.1016/j.cell.2004.07.002 · Cited by 4,251
An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System
Mazmanian, S. K., Liu, C. H., Tzianabos, A. O., & Kasper, D. L. (2005) · Cell · doi:10.1016/j.cell.2005.05.007 · Cited by 2,910
Rescigno, M., Urbano, M., Valzasina, B., Francolini, M., Rotta, G., Bonasio, R., Granucci, F., Kraehenbuhl, J.-P., & Ricciardi‐Castagnoli, P. (2001) · Nature Immunology · doi:10.1038/86373 · Cited by 2,554
Induction of Protective IgA by Intestinal Dendritic Cells Carrying Commensal Bacteria
Macpherson, A. J., & Uhr, T. (2004) · Science · doi:10.1126/science.1091334 · Cited by 1,584
Gewirtz, A. T., Navas, T. A., Lyons, S., Godowski, P. J., & Madara, J. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.4.1882 · Cited by 1,345
Cario, E., & Podolsky, D. K. (2000) · Infection and Immunity · doi:10.1128/iai.68.12.7010-7017.2000 · Cited by 1,245
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
Boone, D. L., Turer, E. E., Lee, E. G., Ahmad, R., Wheeler, M. T., Tsui, C., Hurley, P. J., Chien, M., Chai, S., Hitotsumatsu, O., et al. (2004) · Nature Immunology · doi:10.1038/ni1110 · Cited by 1,104
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- Rook GA, Brunet LR (2005) Microbes, immunoregulation and the gut. Gut 54: 317–320
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Ζουμποπούλου, Γ., Pot, B., Tsakalidou, E., & Papadimitriou, K. (2016) · International Dairy Journal · doi:10.1016/j.idairyj.2016.09.010 · Cited by 74
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Cigarrán, S., Parra, E. G., & Cases, A. (2017) · Nefrología (English Edition) · doi:10.1016/j.nefroe.2017.01.017 · Cited by 71
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Sam, Q. H., Yew, W. S., Seneviratne, C. J., Chang, M. W., & Chai, L. Y. A. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01612 · Cited by 68
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Ifrim, D. C., Joosten, L. A. B., Kullberg, B. J., Jacobs, L., Jansen, T., Williams, D. L., Gow, N. A. R., van der Meer, J. W. M., Netea, M. G., & Quintin, J. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1202611 · Cited by 72
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Marinelli, L., Tenore, G. C., & Novellino, E. (2017) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2017.08.007 · Cited by 64
Zhang, N., Zhang, Y., Li, M., Wang, W., Liu, Z., Xi, C., Huang, X., Liu, J., Huang, J., Tian, D., et al. (2020) · Brain and Behavior · doi:10.1002/brb3.1699 · Cited by 67
Pruteanu, M., Hyland, N. P., Clarke, D. J., Kiely, B., & Shanahan, F. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21475 · Cited by 67
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Staubach, F., Künzel, S., Baines, A. C., Yee, A., McGee, B. M., Bäckhed, F., Baines, J. F., & Johnsen, J. M. (2012) · The ISME Journal · doi:10.1038/ismej.2011.204 · Cited by 69
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Liu, X., Fan, H., Ding, X., Hong, Z.-S., Nei, Y., Liu, Z., Li, G., & Guo, H. (2014) · Current Microbiology · doi:10.1007/s00284-014-0528-5 · Cited by 58
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Rook, G. A. W. (2011) · Digestive Diseases · doi:10.1159/000323877 · Cited by 60
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Huynh, T.-G., Hu, S., Chiu, C.-S., Truong, Q.-P., & Liu, C. (2019) · Aquaculture Research · doi:10.1111/are.13951 · Cited by 57
Yang, H., Liu, Y., Cai, R., Li, Y., & Gu, B. (2021) · Annals of Palliative Medicine · doi:10.21037/apm-20-1365 · Cited by 58
Zhu, Y., Lin, X., Li, H., Li, Y., Shi, X., Zhao, F., Xu, X., Li, C., & Zhou, G. (2016) · PLOS ONE · doi:10.1371/journal.pone.0152678 · Cited by 57
Liu, W., Li, Y., Guo, S., Yin, H., Lei, C., & Wang, X. (2016) · Scientific Reports · doi:10.1038/srep38900 · Cited by 56
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Khanal, P., Maltecca, C., Schwab, C. R., Fix, J., & Tiezzi, F. (2020) · Journal of Animal Breeding and Genetics · doi:10.1111/jbg.12504 · Cited by 61
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Qian, B., Zhang, K., Li, Y., & Sun, K. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.1059349 · Cited by 63
Vitetta, L., Coulson, S., Linnane, A. W., & Butt, H. (2013) · Pathogens · doi:10.3390/pathogens2040606 · Cited by 61
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Dewar, M., Arnould, J. P. Y., Krause, L., Trathan, P. N., Dann, P., & Smith, S. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0099996 · Cited by 59
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Self-citationHalmos, T., & Suba, I. (2015) · Orvosi Hetilap · doi:10.1556/650.2015.30296 · Cited by 58
Metadata
- Authors
- O'Hara, A. M., & Shanahan, F.
- Affiliations
- National University of Ireland (IE)
- Corresponding author
- Shanahan, Fergus
- ORCID
- Shanahan, Fergus
- Venue
- The EMBO Reports
- Published
- 2006-07-01
- Volume
- 7
- Issue
- 7
- Pages
- 688-693
- ISSN
- 1469-221X (ISSN-L)
- 1469-3178
- PMC
- PMC1500832
- OpenAlex
- W2117727476
- Cited by
- 2,791
- References
- 54
- Citations by year
- 2026: 67 · 2025: 127 · 2024: 186 · 2023: 174 · 2022: 230 · 2021: 217 · 2020: 243 · 2019: 198 · 2018: 179 · 2017: 184 · 2016: 168 · 2015: 147 · 2014: 123 · 2013: 134 · 2012: 121
- FWCI
- 3.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- EMBO Reports (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Science Foundation Ireland
- Alimentary Health
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Keywords
- gut microbiota, mucosal immunity, inflammatory bowel disease, mucosal homeostasis, bacterial metabolic activity, microbiome manipulation, intestinal disorders, pathogenesis
- MeSH terms
- Animals, Bacteria, Digestive System, Digestive System Diseases, Germ-Free Life, Homeostasis, Humans, Intestinal Mucosa, Models, Biological, Immunity, Mucosal
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