Hox genes in hematopoiesis and leukemogenesis

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

Golub, T. R., Slonim, D. K., Tamayo, P., Huard, C., Gaasenbeek, M., Mesirov, J. P., Coller, H., Loh, M. L., Downing, J. R., Caligiuri, M. A., et al. (1999) · Science · doi:10.1126/science.286.5439.531 · Cited by 11,516

Identification of human brain tumour initiating cells

Singh, S. K., Hawkins, C. E., Clarke, I. D., Squire, J. A., Bayani, J., Hide, T., Henkelman, R. M., Cusimano, M. D., & Dirks, P. B. (2004) · Nature · doi:10.1038/nature03128 · Cited by 7,564

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Bonnet, D. A., & Dick, J. E. (1997) · Nature Medicine · doi:10.1038/nm0797-730 · Cited by 7,197

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

O'Brien, C. A., Pollett, A. F., Gallinger, S., & Dick, J. E. (2006) · Nature · doi:10.1038/nature05372 · Cited by 4,174

A role for Wnt signalling in self-renewal of haematopoietic stem cells

Reya, T., Duncan, A. W., Ailles, L., Domen, J., Scherer, D. C., Willert, K., Hintz, L., Nusse, R., & Weissman, I. L. (2003) · Nature · doi:10.1038/nature01593 · Cited by 2,159

Hox genes in vertebrate development

Krumlauf, R. K. (1994) · Cell · doi:10.1016/0092-8674(94)90290-9 · Cited by 2,079

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

Yeoh, A. E. J., Ross, M. E., Shurtleff, S. A., Williams, W. K., Patel, D. H., Mahfouz, R. A., Behm, F. G., Raimondi, S. C., Relling, M. V., Patel, A. R., et al. (2002) · Cancer Cell · doi:10.1016/s1535-6108(02)00032-6 · Cited by 1,914

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells.

Park, I.-K., Qian, D., Kiel, M., Becker, M. W., Pihalja, M., Weissman, I. L., Morrison, S. J., & Clarke, M. F. (2003) · Nature · doi:10.1038/nature01587 · Cited by 1,871

Isolation and In vitro Propagation of Tumorigenic Breast Cancer Cells with Stem/Progenitor Cell Properties

Ponti, D., Costa, A., Zaffaroni, N., Pratesi, G., Petrangolini, G., Coradini, D., Pilotti, S., Pierotti, M. A., & Daidone, M. G. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-0626 · Cited by 1,725

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

Armstrong, S. A., Staunton, J. E., Silverman, L. B., Pieters, R., den Boer, M. L., Minden, M. D., Sallan, S. E., Lander, E. S., Golub, T. R., & Korsmeyer, S. J. (2001) · Nature Genetics · doi:10.1038/ng765 · Cited by 1,721

Role of non-coding RNA NC4 in MLL and CYP33 mediated regulation of HOXC8

Solanki, J. A. (2011) · Loyola eCommons (Loyola University of Chicago) · Cited by 1

Molecular pathology of leukemia

Albitar, M. X., & Donahue, A. C. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511781926.001 · Cited by 1

The Role of MicroRNAs in Hematopoietic Stem Cells and Leukemia Development

Yalcin, S., Chung, S. S., & Park, C. Y. (2014) · Springer eBooks · doi:10.1007/978-1-4899-8065-6_8 · Cited by 1

Impact Of Tgiflx Expression On The Regulation Of Bcl2 And Bax In Prostate Cancer Cell Line (Lncap)

Raoofian, R., Mojarrad, M., Heidari, M., & Sciences, T. (2013) · Zenodo (CERN European Organization for Nuclear Research) · doi:10.5281/zenodo.7937 · Cited by 1

Current Insights in the Cellular and Molecular Biology of Chronic Myelomonocytic Leukemia

Itzykson, R., Droin, N. M., & Solary, É. (2012) · International Journal of Hematologic Oncology · doi:10.2217/ijh.12.19 · Cited by 1

Stem Cells in Leukemia and Other Hematological Malignancies

Copland, M., Michie, A. M., & Holyoake, T. L. (2009) · Springer eBooks · doi:10.1007/978-0-387-89611-3_5 · Cited by 1

The role and epigenetic regulation of the CDX gene family in human cancer

(2015) · Stem Cell Epigenetics · doi:10.14800/sce.882 · Cited by 1

State of Chromosome 11q23 in T-ALL/LBL and Their Relation to Prognosis

Wang, J., Li, J., Xi, Y., & Bai, W. (2012) · Applied Immunohistochemistry · doi:10.1097/pai.0b013e31822d1198 · Cited by 1

HIGH CDX2 GENE EXPRESSION PREDICTS INFERIOR PROGNOSIS IN ACUTE MYELOID LEUKEMIA PATIENTS WITH NORMAL CYTOGENETICES.

ShereenMohamedEl-Hoseiny, M. D., HananAliTaha, M. D., NillyHelmyMohamed, M. D., & Sayed, S. (2016) · International Journal of Advanced Research · doi:10.21474/ijar01/2514 · Cited by 1

Poly zinc finger protein ZFP14 suppresses lymphomagenesis and abnormal inflammatory response via the HOXA gene cluster

Mohibi, S., Chen, M., Chen, X., & Zhang, J. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2022.166587 · Cited by 1

Transcriptional Landscape of CUT-Class Homeobox Genes in Blastic Plasmacytoid Dendritic Cell Neoplasm

Nagel, S., Rand, U., Pommerenke, C., & Meyer, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25052764 · Cited by 1

Basic principles of multipotent stem cells

Kumar, A., & Verfaillie, C. M. (2012) · Elsevier eBooks · doi:10.1533/9780857096074.1.100 · Cited by 1

Expression Analysis of Homeobox Genes in Leukemia/Lymphoma Cell Lines

Nagel, S., & Drexler, H. G. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-080-5_30 · Cited by 1

Hox Protein Interactions: Screening and Network Building

Bergiers, I., Lambert, B., Daakour, S., Twizere, J., & Rezsöhazy, R. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1242-1_20 · Cited by 1

Targeted deletion of the Hoxa cluster affects B lymphopoiesis through depletion of early lymphoid progenitors

Lebert‐Ghali, C., Thompson, A., Melichar, H. J., & Bijl, J. J. (2017) · Experimental Hematology · doi:10.1016/j.exphem.2017.03.003 · Cited by 1

Cancer Stem Cells in the Development of Novel Therapeutics for Refractory Pediatric Leukemia

Brennan, L. C., & Narendran, A. (2019) · Stem Cells and Development · doi:10.1089/scd.2019.0035 · Cited by 1

Homeobox A5 and A9 expression and beta-thalassemia

Badr, E., El-Sayed, I.-T., & Alasadi, M. (2021) · British Journal of Biomedical Science · doi:10.1080/09674845.2021.1877926 · Cited by 1

Sensitivity of Hematopoietic and Leukemic Stem Cells to Hoxa Gene Levels

Lebert‐Ghali, C., Ramsey, J. M., Thompson, A., & Bijl, J. J. (2011) · Springer eBooks · doi:10.1007/978-94-007-2828-8_2 · Cited by 1

Maintenance and expansion of hematopoietic stem cells in vitro using genetic methods

Wu, Z. (2011) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/47581 · Cited by 1

Expressão dos membros da familia HOX de genes homeobox dos loci A e D em linhagens celulares e tecidos orais de mucosa normal e carcinoma espinocelular

Bitu, C. C. (2008) · doi:10.47749/t/unicamp.2008.416271 · Cited by 1

Acute lymphoblastic leukemia (ALL)

Paz‐Priel, I., & Friedman, A. D. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139046947.072 · Cited by 1

High Density Domain-Focused CRISPR Screens Reveal Novel Epigenetic Regulators of HOX/MEIS Activation in Acute Myeloid LeukemiaPreprint

Barbosa, K., Deshpande, A. J., Perales, M., Xiang, P., Murad, R., Minkina, A., Robertson, N., Schischlik, F., Lei, X., Sun, Y., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.12.12.519332 · Cited by 1

Dysregulated expression of Hoxa1 isoforms in hematopoietic stem and progenitor cells causes myelodysplastic syndromesPreprint

Tan, S., Joseph, C. J., Sobah, M. L., Chalk, A. M., Schleibs, K., Lee, S. C., Tjin, G., Chugh, S., Mo, X., Grace, C. S., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.04.24.538176 · Cited by 1

FUNCTIONS OF THE HOMEOBOX GENE DLX4 IN CONTROLLING INFLAMMATORY SIGNALING AND METASTASIS OF EPITHELIAL OVARIAN CANCER

Haria, D. (2014) · Digital Commons-TMC (Texas Medical Center)

Examining the effect of CBP on the E2A-PBX1 and HOXB4 interaction

Menezes, S. C. (2008)

Étude de la voie HOX-Flt3 dans les leucémies de type pré-B induites par E2A-Pbx1

Vaisson, G. (2013) · doi:10.71781/27561

Mechanisms of MLL Fusion Protein-Mediated Leukemic Transformation

Monroe, S. (2010) · Deep Blue (University of Michigan)

Diagnosis of Leukemias: New Diagnostic Modalities and Implications for Classification

Albitar, M. X. (2010) · doi:10.1002/9781444327359.ch4

Defining novel therapeutic targets in chronic myeloid leukaemia stem cells : targeting self-renewal through hedgehog pathway inhibition

Irvine, D. A. (2013) · Enlighten: Theses (The University of Glasgow)

Molecular Morphogenesis of T-Cell Acute Leukemia

Litt, M. D., Patel, B., Li, Y., Qiu, Y., & Huang, S. (2013) · InTech eBooks · doi:10.5772/55144

MicroRNAs in Pediatric Acute Lymphoblastic Leukemia: Small players with huge potential

Schotte, D. (2011) · RePub (Erasmus University Rotterdam)

Identificación y caracterización funcional de nuevos factores de transcripción implicados en la progresión leucémica y la hematopoyesis

Jimenez, F. A. (2011) · doi:10.14201/gredos.110637

L’effet de HOXB4 sur l’expansion et la différenciation des progéniteurs myéloïdes

Helici, I. C. (2009) · doi:10.71781/29429

Hox genes and mesenchymal stem cells

Ackema, K. B. (2007) · EUR Research Repository (Erasmus University Rotterdam)

Molecular Functions of MLL PHD3 Binding to Its Ligands Cyp33 and H3K4Me3

Raman, G. (2013) · Loyola eCommons (Loyola University of Chicago)

THE HYPOXIC HEMATOPOIETIC STEM CELL NICHE Consequences of Hypoxia-induced Transcription on Stem Cell Fate

Rehn, M. (2011) · Lund University Publications (Lund University)

Precursor T-Cell Neoplasms

Keersmaecker, K. D., & Ferrando, A. A. (2010) · Molecular pathology library · doi:10.1007/978-1-4419-5698-9_26

Homeobox Genes and Their Functional Significance in Ovarian Tumorigenesis

Trinh, B. Q., & Naor, H. (2012) · InTech eBooks · doi:10.5772/27549

HOX Genes: What their Investigation Could Mean for Acute Myeloid Leukemia

Braekeleer, M. D. (2014) · International Journal of Hematologic Oncology · doi:10.2217/ijh.14.20

Cancer stem cell patents

Kvinlaug, B. T., & Lazic, S. E. (2008) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543770802553764

Mécanisme d’action des oncogènes à homéodomaine TLX dans les LAL-T

Asnafi, V., & Ferrier, P. (2012) · médecine/sciences · doi:10.1051/medsci/2012288012

High-Resolution Analysis of Chromosomal Alterations in Adult Acute Lymphoblastic Leukemia

Yuen, L. K., Zakaria, Z., Bong, I. P. N., Noor, M. B. P. J., Esa, E., Meng, C. Y., Ong, T. C., Subramanian, V., & Meng, C. K. (2014) · Journal of Hematology

Molecular Genetic Insights in Cytogenetically-Normal Pediatric Acute Myeloid Leukemia

Hollink, I. H. I. M. (2011) · RePub (Erasmus University Rotterdam)

Targeting the Epigenetic Lesion in MLL-Rearranged Leukemia

Chen, L. M. (2013) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Pathophysiologie der Blutbildung bei Patienten mit Thrombocytopenia absent radii (TAR)-Syndrom

Wannack, M. (2011) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-14663

transcript within the human HOXA cluster A myelopoiesis-associated regulatory intergenic non-coding RNA

Gingeras, T., Kapranov, P., Weissman, S. M., Newburger, P. E., Zhang, X., Lian, Z., Padden, C., Gerstein, M., Rozowsky, J. S., & Snyder, M. P. (2009)

USING A TRANSGENIC ZEBRAFISH MODEL TO IDENTIFY DOWNSTREAM THERAPEUTIC TARGETS IN HIGH-RISK, NUP98-HOXA9-INDUCED MYELOID DISEASE

Adam, D. (2016) · DalSpace (Dalhousie University)

Characterization of the Hoxd4 neural enhancer

Ler, S. Y. (2012) · doi:10.32657/10356/50718

Identification of the molecular partners that regulate MEIS1A function

Ravishankar, C. (2013) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/59111

Prognostic significance of nucleophosmin mutations in pediatric acute leukemia

Kuzmanović, M. (2013) · doi:10.2298/bg20130404kuzmanovic

AVALIAÇÃO DO PERFIL DE EXPRESSÃO GÊNICA DE CÉLULAS CD34+ E CÉLULAS CD133+ ISOLADAS DE MEDULA ÓSSEA E DE SANGUE DE CORDÃO UMBILICAL

Filho, M. (2008)

Molecular Origin of Childhood Acute Lymphoblastic Leukemia

Waanders, E., Jongmans, M. C. J., & Mullighan, C. G. (2016) · Springer eBooks · doi:10.1007/978-3-319-05798-9_7

Identification and characterization of E2A-PBX1 genomic binding sites using ChIP-seq and bioinformatics

Nanan, K. K. (2014) · QSpace (Queen's University Library)

Regulation of E Protein Activity During Dendritic Cell Development

Grajkowska, L. T. (2015) · Columbia Academic Commons (Columbia University) · doi:10.7916/d8bv7frn

The Role of the MLL-HOXA9 Axis in Normal and Malignant Hematopoiesis.

Wang, J. (2013) · Deep Blue (University of Michigan)

Alterações genéticas, epigenéticas e funcionais dos genes homeobox em carcinoma epidermoide de boca

Duarte, C. M. E. (2016) · doi:10.11606/t.23.2016.tde-25022016-155104

Identification and functional analysis of gene expression changes in acute myeloid leukaemia.

Kok, C. H. (2010) · Adelaide Research & Scholarship (AR&S) (University of Adelaide)

Epigenetic Dysregulation in Pediatric Leukemia

Madhusoodhan, P. P., Carroll, W. L., & Bhatla, T. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809552-2.00001-2

Targeting the menin-MLL-LEDGF Interaction with Small Molecule Inhibitors.

Pollock, J. (2016) · Deep Blue (University of Michigan)

Drosophila Hox genes induce melanised pseudo-tumours when misexpressed in hemocytesPreprint

Ponratnam, T., Saini, R., & Mishra, R. K. (2020) · doi:10.21203/rs.2.20010/v2

The NADPH oxidase-induced phagosomal environment of neutrophils and other phagocytes

Foote, J. R. (2019) · UCL Discovery (University College London)

Identification of an acute myeloid leukaemia associated noncoding somatic mutation at 3 $$^\prime $$ ′ end of HOXA cluster

Xu, X., Song, L., Zhao, Y., Wang, L., Zhang, X., Shen, Z., Zhao, C., & Hu, Z. (2019) · Journal of Genetics · doi:10.1007/s12041-019-1081-6

Construction of hybrid yeast-human histone methyltransferase complexes in Saccharomyces cerevisiae clarifies the roles of Bre2 and Ash2L for mixed lineage leukemia

Klein, D. C., Lal, A., Longan, E. R., Baker, M., Gogoli, S., Wang, J., Alkoutami, S. S., Zibas, E., & Chosed, R. J. (2018) · Biomedical Genetics and Genomics · doi:10.15761/bgg.1000142

Untersuchungen zu pathomolekularen Funktionen von t(4;11) Fusionsproteinen

Siemund, A. L. (2022) · Publication Server of Goethe University Frankfurt am Main (Goethe University Frankfurt) · doi:10.21248/gups.67691

Faculty Opinions recommendation of Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression.

Meisterernst, M. (2009) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.1166540.627541

Drosophila Hox genes induce melanised pseudo-tumours when misexpressed in hemocytesPreprint

Ponratnam, T., Saini, R., & Mishra, R. K. (2020) · doi:10.21203/rs.2.20010/v1

Phase-separated nuclear bodies of nucleoporin fusions, SET-NUP214 and NUP98-HOXA9, promote condensation of MLL1 and CRM1 to activate target genesPreprint

Oka, M., Otani, M., Miyamoto, Y., Adachi, J., Tomonaga, T., Asally, M., Ohkawa, Y., & Yoneda, Y. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.24.493212

Progenitor-like cell type of an MLL-EDC4 fusion in acute myeloid leukemia

Schuster, L. C., Syed, A. P., Tirier, S. M., Steiger, S., Seufert, I., Becker, H., Duque‐Afonso, J., Ma, T., Ogawa, S., Mallm, J., et al. (2023) · Blood Advances · doi:10.1182/bloodadvances.2022009096

Human lymphoid-neutrophil/monocyte restriction co-ordinately activates increased proliferation despite parallel heterogeneity in transcriptional changesPreprint

Wang, F., Gonzalez, L., Hammond, C. A., Hirst, M., Simons, B. D., & Eaves, C. J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.18.580894

Histologic variants in bladder cancer harbor aggressive molecular features including TM4SF1 expression and a CA125+ cell statePreprint

Yang, H., Song, H., Yip, E., Chang, K., Allegakoen, P., Lu, K. L., Hui, K. S. F., Pham, J. H., Kasap, C., Kumar, V., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.20.595039

Análise do papel dos genes HOX na regulação de vias gênicas compartilhadas entre o desenvolvimento placentário e tumoral

Brotto, D. B. (2019) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2019.tde-04072024-141028

Regulation of flt3 gene expression in haematopoietic and leukaemic stem cells

Volpe, G. (2010) · University of Birmingham Institutional Research Archive (University of Birmingham)

Role of the Notch1 TAD in embryonic development and hematopoiesis

Gerhardt, D. (2014) · ScholarlyCommons (University of Pennsylvania)

Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia

Clayfield, L., Malik, D., Whittle, J., Xu, J., Mével, R., Fadlullah, M. Z. H., Patel, R., Szpakowska, M., Maqbool, M. A., Jones, M., et al. (2026) · Cell Reports · doi:10.1016/j.celrep.2025.116875

TIF1 gamma est un régulateur essentiel de l'hématopoïèse et agit en tant que suppresseur de tumeur dans la leucémie myélomonocytaire chronique

Aucagne, R. (2010) · doi:10.70675/b6296779z0f3dz4edbza752z54638748635e

Rôle des facteurs de transcription HIF (Hypoxia Inducible Factor) dans le maintien à long terme des cellules souches hématopoïétiques humaines chez la souris immunodéficiente

Rouault-Pierre, K. (2010) · theses.fr (ABES) · doi:10.70675/d19021d9z37c5z4948zb727z5f042b13da9d

Blocage de maturation thymique et aberration des recombinaisons V(D)J : modèle des Leucémies Aigües Lymphoblastiques de la lignée T exprimant les onco-protéines à homéodomaines TLX1 et TLX3

Dadi, S. (2010) · theses.fr (ABES) · doi:10.70675/fa8bf898z0befz4327z91cazaecc888973c0

Détection des anomalies génétiques dans les LAL-T : de la biologie à la clinique

Abdelali, R. B. (2011) · theses.fr (ABES) · doi:10.70675/90f2a16fz3cdez41f5z8dfez0848b91eb777

Etude du rôle des régulateurs Post-transcriptionnels Pumilio dans les cellules souches hématopoïétiques humaines

Miri-Nezhad, A. (2013) · theses.fr (ABES) · doi:10.70675/a7321c69z76d9z4e51z831dzd5ff75041fbd

Cellular and molecular mechanisms underlying the role played by the MEN1 gene in prostate cancer cells

Luo, Y. (2021) · theses.fr (ABES) · doi:10.70675/2cb2dd05z5a31z4d0dzb763zebc97e929bad

Unlocking the HOX: Homeobox Genes as Regulators of Hematopoietic Development

Moyer, D. L., Henning, A. M., & Medina, K. L. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27073285

Modifications du microenvironnement cytokinique dans les leucémies aigües myéloïdes

Guermouche, H. (2021) · theses.fr (ABES) · doi:10.70675/e0e649a1z9428z4e58z93b3z0b5d7ec2fea8

Complications hématologiques du syndrome de Shwachman-Diamond : neutropénie et leucémie aiguë myéloïde

Martignoles, J. (2022) · theses.fr (ABES) · doi:10.70675/dc56799dzc2f9z460fz892az3a689bd2251a

The role of MEIS inhibitors in cardiac regeneration and protection

Mammadova, A. (2024) · doi:10.70675/26f419bdzeecdz4816z8ff0z9800989c228b

Modeling Chronic Myelomonocytic Leukemia with the Aim of Identifying Novel Therapeutic Targets

Alawieh, D. (2025) · theses.fr (ABES) · doi:10.70675/c7daf13fz397fz4894zbafezd95092b27414

Structure-based design of the approved drug zafirlukast identifies HLC40 as a potent WDR5 WIN-site inhibitor with antitumor efficacy

He, L., Shen, C., Fan, C., Li, Y., Liu, S., Song, J., Zheng, T., Huang, X., Wen, J., Xu, J., et al. (2026) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2026.109869

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Jiang, Y., Zhong, F., Liu, R., & Zhang, X. (2026) · Aging and Cancer · doi:10.1002/aac2.70021

Functional analyses of Hox genes and development of molecular markers associated with growth and morphology in the red swamp crayfish, Procambarus clarkii

Wei, X., Hu, Q., Chen, D., Wang, Y., Liu, Y., & Yan-he, L. (2026) · Aquaculture · doi:10.1016/j.aquaculture.2026.744224

The human leukemic fusion protein MLL-AF4 promotes autophagy and cell death in the fat body of Drosophila melanogasterPreprint

Haukeland, A. L. C., Johannessen, J. A., Bråthen, N. R., Bergeron, P., Formica, M., Enserink, J. M., & Knævelsrud, H. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.01.735327

BindingDB Entry 50039158: Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction.

BindingDB (2012) · UC San Diego · doi:10.7270/q2086678

BindingDB Entry 50014300: Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity.

BindingDB (2022) · UC San Diego · doi:10.7270/q2j38xcr

BindingDB Entry 50048213: High-affinity small molecular blockers of mixed lineage leukemia 1 (MLL1)-WDR5 interaction inhibit MLL1 complex H3K4 methyltransferase activity.

BindingDB (2018) · UC San Diego · doi:10.7270/q2251m6g

BindingDB Entry 50048029: Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia.

BindingDB (2018) · UC San Diego · doi:10.7270/q2tm7d4p

BindingDB Entry 50047884: Structure-based design of ester compounds to inhibit MLL complex catalytic activity by targeting mixed lineage leukemia 1 (MLL1)-WDR5 interaction.

BindingDB (2018) · UC San Diego · doi:10.7270/q2f47r4k

BindingDB Entry 50042590: TBA

BindingDB (2013) · UC San Diego · doi:10.7270/q2c53n6f

REMANIEMENTS DU GENE NUP98 DANS LES HEMOPATHIES MALIGNES HUMAINES

Petit, A. (2010) · HAL

Significance of Protein Interactions in Mediating AF9 Function

Malik, B. (2013) · Loyola eCommons (Loyola University of Chicago)

Estudo da expressão imunoistoquimica de KI-67, Mcm-2 e HOXB7 em neoplasias basaloides de cabeça e pescoço

Rocha, L. A. (2010) · doi:10.47749/t/unicamp.2010.478141

Hox regulation of normal and leukemic hematopoietic stem cells

Abramovich, C., & Humphries, R. K. (2005) · Current Opinion in Hematology · doi:10.1097/01.moh.0000160737.52349.aa · Cited by 164

Hox Genes: From Leukemia to Hematopoietic Stem Cell Expansion

Abramovich, C., Pineault, N., OHTA, H., & Humphries, R. K. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1349.014 · Cited by 81

The Role of HOX Homeobox Genes in Normal and Leukemic Hematopoiesis

Lawrence, H. J., Sauvageau, G., Humphries, R. K., & Largman, C. (1996) · Stem Cells · doi:10.1002/stem.140281 · Cited by 241

HOXandNon‐HOXHomeobox Genes in Leukemic Hematopoiesis

Owens, B. M., & Hawley, R. G. (2002) · Stem Cells · doi:10.1634/stemcells.20-5-364 · Cited by 165

Leukemogenic Transformation by Anterior HOXA-Cluster Genes.

Buhl, S., Maethner, E., & Slany, R. K. (2009) · Blood · doi:10.1182/blood.v114.22.2962.2962