The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
RETRACTED ARTICLE: Increased Gut Redox and Depletion of Anaerobic and Methanogenic Prokaryotes in Severe Acute Malnutrition
Open accessAbstract
Severe acute malnutrition (SAM) is associated with inadequate diet, low levels of plasma antioxidants and gut microbiota alterations. The link between gut redox and microbial alterations, however, remains unexplored. By sequencing the gut microbiomes of 79 children of varying nutritional status from three centers in Senegal and Niger, we found a dramatic depletion of obligate anaerobes in malnutrition. This was confirmed in an individual patient data meta-analysis including 107 cases and 77 controls from 5 different African and Asian countries. Specifically, several species of the Bacteroidaceae, Eubacteriaceae, Lachnospiraceae and Ruminococceae families were consistently depleted while Enterococcus faecalis, Escherichia coli and Staphylococcus aureus were consistently enriched. Further analyses on our samples revealed increased fecal redox potential, decreased total bacterial number and dramatic Methanobrevibacter smithii depletion. Indeed, M. smithii was detected in more than half of the controls but in none of the cases. No causality was demonstrated but, based on our results, we propose a unifying theory linking microbiota specificity, lacking anaerobes and archaea, to low antioxidant nutrients, and lower food conversion.
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von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., Vandenbroucke, J. P., & Initiative, F. T. S. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040296 · Cited by 23,020
Human gut microbiome viewed across age and geography
Yatsunenko, T., Rey, F. E., Manary, M. J., Trehan, I., Dominguez-Bello, M. G., Contreras, M., Magris, M., Hidalgo, G., Baldassano, R. N., Anokhin, A. P., et al. (2012) · Nature · doi:10.1038/nature11053 · Cited by 7,815
Human gut microbiota in obesity and after gastric bypass
Zhang, H., DiBaise, J. K., Zuccolo, A., Kudrna, D., Braidotti, M., Yu, Y., Parameswaran, P., Crowell, M. D., Wing, R., Rittmann, B. E., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812600106 · Cited by 1,880
Samuel, B. S., Shaito, A., Motoike, T., Rey, F. E., Backhed, F., Manchester, J. K., Hammer, R. E., Williams, S. C., Crowley, J., Yanagisawa, M., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808567105 · Cited by 1,564
Persistent gut microbiota immaturity in malnourished Bangladeshi children
Subramanian, S., Huq, S., Yatsunenko, T., Haque, R., Mahfuz, M., Alam, M. A., Benezra, A., DeStefano, J., Meier, M. F., Muegge, B. D., et al. (2014) · Nature · doi:10.1038/nature13421 · Cited by 1,270
Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor
Smith, M. I., Yatsunenko, T., Manary, M. J., Trehan, I., Mkakosya, R., Cheng, J., Kau, A. L., Rich, S. S., Concannon, P., Mychaleckyj, J. C., et al. (2013) · Science · doi:10.1126/science.1229000 · Cited by 1,173
A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism
Samuel, B. S., & Gordon, J. I. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602187103 · Cited by 674
Kashyap, P. C., Marcobal, A., Ursell, L. K., Smits, S. A., Sonnenburg, E. D., Costello, E. K., Higginbottom, S. K., Domino, S. E., Holmes, S. P., Relman, D. A., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1306070110 · Cited by 285
Gut microbiota of healthy and malnourished children in bangladesh
Monira, S., Nakamura, S., Gotoh, K., Izutsu, K., Watanabe, H., Alam, N. H., Endtz, H. P., Cravioto, A., Ali, S. I., Nakaya, T., et al. (2011) · Frontiers in Microbiology · doi:10.3389/fmicb.2011.00228 · Cited by 223
Shankar, V., Hamilton, M. J., Khoruts, A., Kilburn, A., Unno, T., Paliy, O., & Sadowsky, M. J. (2014) · Microbiome · doi:10.1186/2049-2618-2-13 · Cited by 106
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Lagier, J.-C., Dubourg, G., Million, M., Cadoret, F., Bilen, M., Fenollar, F., Levasseur, A., Rolain, J.-M., Fournier, P.-E., & Raoult, D. (2018) · Nature Reviews Microbiology · doi:10.1038/s41579-018-0041-0 · Cited by 872
Self-citationThe Human Microbiome and Child Growth – First 1000 Days and Beyond
Robertson, R. C., Manges, A. R., Finlay, B. B., & Prendergast, A. J. (2019) · Trends in Microbiology · doi:10.1016/j.tim.2018.09.008 · Cited by 793
Honeybee gut microbiota promotes host weight gain via bacterial metabolism and hormonal signaling
Zheng, H., Powell, J. E., Steele, M. I., Dietrich, C., & Moran, N. A. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1701819114 · Cited by 664
Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade
Ferrere, G., Tidjani Alou, M., Liu, P., Goubet, A.-G., Fidelle, M., Kepp, O., Durand, S., Iebba, V., Fluckiger, A., Daillère, R., et al. (2021) · JCI Insight · doi:10.1172/jci.insight.145207 · Cited by 533
Self-citationGut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
Andrews, M. C., Duong, C. P. M., Gopalakrishnan, V., Iebba, V., Chen, W.-S., Derosa, L., Khan, M. A. W., Cogdill, A. P., White, M. G., Wong, M. C., et al. (2021) · Nature Medicine · doi:10.1038/s41591-021-01406-6 · Cited by 437
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Metadata
- Authors
- Million, M., Tidjani Alou, M., Khelaifia, S., Bachar, D., Lagier, J.-C., Dione, N., Brah, S., Hugon, P., Lombard, V., Armougom, F., Fromonot, J., Robert, C., Michelle, C., Diallo, A., Fabre, A., Guieu, R., Sokhna, C., Henrissat, B., Parola, P., & Raoult, D.
- Venue
- Scientific Reports
- Published
- 2016-05-17
- Volume
- 6
- Issue
- 1
- Pages
- 26051-26051
- ISSN
- 2045-2322 (ISSN-L)
- OpenAlex
- W2395121817
- Cited by
- 204
- References
- 10
- FWCI
- 12.79
- Type
- journal article
- Language
- en
- Status
- Retracted
- Open access
- gold
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- Million, M., Tidjani Alou, M., Khelaifia, S., Bachar, D., Lagier, J.-C., Dione, N., Brah, S., Hugon, P., Lombard, V., Armougom, F., Fromonot, J., Robert, C., Michelle, C., Diallo, A., Fabre, A., Guieu, R., Sokhna, C., Henrissat, B., Parola, P., & Raoult, D. (2016). RETRACTED ARTICLE: Increased Gut Redox and Depletion of Anaerobic and Methanogenic Prokaryotes in Severe Acute Malnutrition. Scientific Reports. https://doi.org/10.1038/srep26051
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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