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Cited by 255

The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.

Lab-on-a-Foil: microfluidics on thin and flexible films

Focke, Maximilian, Kosse, Dominique, Müller, Claas, Reinecke, Holger, Zengerle, Roland, von Stetten, Felix·2010·Lab on a Chip
DOI 10.1039/c001195a
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Abstract

This critical review is motivated by an increasing interest of the microfluidics community in developing complete Lab-on-a-Chip solutions based on thin and flexible films (Lab-on-a-Foil). Those implementations benefit from a broad range of fabrication methods that are partly adopted from well-established macroscale processes or are completely new and promising. In addition, thin and flexible foils enable various features like low thermal resistance for efficient thermocycling or integration of easily deformable chambers paving the way for new means of on-chip reagent storage or fluid transport. From an economical perspective, Lab-on-a-Foil systems are characterised by low material consumption and often low-cost materials which are attractive for cost-effective high-volume fabrication of self-contained disposable chips. The first part of this review focuses on available materials, fabrication processes and approaches for integration of microfluidic functions including liquid control and transport as well as storage and release of reagents. In the second part, an analysis of the state of Lab-on-a-Foil applications is provided with a special focus on nucleic acid analysis, immunoassays, cell-based assays and home care testing. We conclude that the Lab-on-a-Foil approach is very versatile and significantly expands the toolbox for the development of Lab-on-a-Chip solutions.

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Metadata

Authors
Focke, M., Kosse, D., Müller, C., Reinecke, H., Zengerle, R., & von Stetten, F.
Venue
Lab on a Chip
Publisher
Royal Society of Chemistry (RSC)
Published
2010
Volume
10
Issue
11
Pages
1365
ISSN
  • 1473-0189 (ISSN-L)
  • 1473-0197
DOI
10.1039/c001195a
OpenAlex
W2106342535
Cited by
255
References
72
FWCI
11.29
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Lab-on-a-Foil: microfluidics on thin and flexible films. https://app.cochat.ai/papers/10.1039/c001195a
The paper
Focke, M., Kosse, D., Müller, C., Reinecke, H., Zengerle, R., & von Stetten, F. (2010). Lab-on-a-Foil: microfluidics on thin and flexible films. Lab on a Chip. https://doi.org/10.1039/c001195a

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.