The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Mesoporous silica nanoparticle based nano drug delivery systems: synthesis, controlled drug release and delivery, pharmacokinetics and biocompatibility
Abstract
The biomedical applications of mesoporous silica nanoparticles (MSNs) as efficient drug delivery carriers have attracted great attention in the last decade. The structure, morphology, size, and surface properties of MSNs have been found to be facilely tunable for the purposes of drug loading, controlled drug release and delivery, and multifuctionalization. Meanwhile, the biosafety and in vivo drug efficiency of MSN-based nano drug delivery systems (nano-DDSs), involving biocompatibility (including cytotoxicity, blood and tissue compatibility) and pharmacokinetics (including biodistribution, biodegradation, retention, excretion, blood circulation) are also drawing increasing attention because of their clinical application prospects. Herein, we review the most recent research progresses on the synthesis, controlled drug release and delivery, pharmacokinetics and biocompatibility of MSNs.
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Citations
Cites
Mesoporous silica nanoparticles for drug delivery and biosensing applications
Slowing, I. I., Trewyn, B. G., Giri, S., & Lin, V. S. ‐. (2007) · Advanced Functional Materials · doi:10.1002/adfm.200601191 · Cited by 1,699
New developments in ordered mesoporous materials for drug delivery
Manzano, M., & Vallet-Regí, M. (2010) · Journal of Materials Chemistry · doi:10.1039/b922651f · Cited by 359
Photo-Driven Expulsion of Molecules from Mesostructured Silica Nanoparticles
Angelos, S., Choi, E., Vögtle, F., De Cola, L., & Zink, J. I. (2007) · The Journal of Physical Chemistry C · doi:10.1021/jp070721l · Cited by 227
Cited by
Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review
Hossen, S., Hossain, M. K., Basher, M. K., Mia, M. N. H., Rahman, M. T., & Uddin, M. J. (2019) · Journal of Advanced Research · doi:10.1016/j.jare.2018.06.005 · Cited by 998
Hollow‐Structured Mesoporous Materials: Chemical Synthesis, Functionalization and Applications
Li, Y., & Shi, J. (2014) · Advanced Materials · doi:10.1002/adma.201305319 · Cited by 759
Self-citationPolyphenol‐Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery
Guo, Y., Sun, Q., Wu, F., Dai, Y., & Chen, X. (2021) · Advanced Materials · doi:10.1002/adma.202007356 · Cited by 650
Croissant, J. G., Fatieiev, Y., Almalik, A., & Khashab, N. M. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201700831 · Cited by 594
Study of the in vitro cytotoxicity testing of medical devices
LI, W., ZHOU, J., & XU, Y. (2015) · Biomedical Reports · doi:10.3892/br.2015.481 · Cited by 461
Metadata
- Authors
- He, Q., & Shi, J.
- Venue
- Journal of Materials Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2011
- Volume
- 21
- Issue
- 16
- Pages
- 5845
- ISSN
- 0959-9428 (ISSN-L)
- 1364-5501
- OpenAlex
- W2060887828
- Cited by
- 691
- References
- 3
- FWCI
- 33.15
- Type
- journal article
- Language
- en
- Open access
- closed
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- He, Q., & Shi, J. (2011). Mesoporous silica nanoparticle based nano drug delivery systems: synthesis, controlled drug release and delivery, pharmacokinetics and biocompatibility. Journal of Materials Chemistry. https://doi.org/10.1039/c0jm03851b
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