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Lyotropic liquid crystal engineering–ordered nanostructured small molecule amphiphileself-assembly materials by design
Open accessAbstract
Future nanoscale soft matter design will be guided to a large extent by the teachings of amphiphile (lipid or surfactant) self-assembly. Ordered nanostructured lyotropic liquid crystalline mesophases may form in select mixtures of amphiphile and solvent. To reproducibly engineer the low energy amphiphile self-assembly of materials for the future, we must first learn the design principles. In this critical review we discuss the evolution of these design rules and in particular discuss recent key findings regarding (i) what drives amphiphile self-assembly, (ii) what governs the self-assembly structures that are formed, and (iii) how can amphiphile self-assembly materials be used to enhance product formulations, including drug delivery vehicles, medical imaging contrast agents, and integral membrane protein crystallisation media. We focus upon the generation of 'dilutable' lyotropic liquid crystal phases with two- and three-dimensional geometries from amphiphilic small molecules (225 references).
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Cites
Lipinski, C. A., Lombardo, F., Dominy, B. W., & Feeney, P. J. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00129-0 · Cited by 18,139
Lipinski, C. A., Lombardo, F., Dominy, B. W., & Feeney, P. J. (1997) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(96)00423-1 · Cited by 11,385
Elastic Properties of Lipid Bilayers: Theory and Possible Experiments
Helfrich, W. (1973) · Zeitschrift für Naturforschung C · doi:10.1515/znc-1973-11-1209 · Cited by 6,141
Theory of self-assembly of hydrocarbon amphiphiles into micelles and bilayers
Israelachvili, J. N., Mitchell, D. J., & Ninham, B. W. (1976) · Journal of the Chemical Society, Faraday Transactions 2 · doi:10.1039/f29767201525 · Cited by 5,205
The Hydrophobic Effect: Formation of Micelles and Biological Membranes
Tanford, C. (1991) · Medical Entomology and Zoology · Cited by 3,327
Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer
Malam, Y., Loizidou, M., & Seifalian, A. M. (2009) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2009.08.004 · Cited by 1,318
How proteins produce cellular membrane curvature
Zimmerberg, J., & Kozlov, M. M. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1784 · Cited by 1,278
Designing peptide based nanomaterials
Ulijn, R. V., & Smith, A. M. (2008) · Chemical Society Reviews · doi:10.1039/b609047h · Cited by 1,132
Hydration forces between phospholipid bilayers
Rand, R. P., & Parsegian, V. A. (1989) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(89)90010-5 · Cited by 1,125
Structure of the inverted hexagonal (HII) phase, and non-lamellar phase transitions of lipids
Seddon, J. M. (1990) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(90)90002-t · Cited by 1,089
Multimodality Imaging Probes: Design and Challenges
Louie, A. (2010) · Chemical Reviews · doi:10.1021/cr9003538 · Cited by 1,044
Mitchell, D. J., Tiddy, G. J. T., Waring, L., Bostock, T., & McDonald, M. P. (1983) · Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases · doi:10.1039/f19837900975 · Cited by 1,015
The Hydrophobic Effect and the Organization of Living Matter
Tanford, C. (1978) · Science · doi:10.1126/science.653353 · Cited by 985
Novel applications of liposomes
Lasic, D. (1998) · Trends in Biotechnology · doi:10.1016/s0167-7799(98)01220-7 · Cited by 867
Pebay-Peyroula, E., Rummel, G., Rosenbusch, J. P., & Landau, E. M. (1997) · Science · doi:10.1126/science.277.5332.1676 · Cited by 860
The hydrophobic effect: Formation of micelles and biological membranes
Gruen, D. W. R., & Haydon, D. A. (1980) · Journal of Colloid and Interface Science · doi:10.1016/0021-9797(80)90338-0 · Cited by 710
The phase diagram of the monoolein/water system: metastability and equilibrium aspects
Qiu, H., & Caffrey, M. (2000) · Biomaterials · doi:10.1016/s0142-9612(99)00126-x · Cited by 640
Liposomal Nanocapsules in Food Science and Agriculture
Taylor, T. M., Weiss, J., Davidson, P. M., & Bruce, B. D. (2005) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390591001135 · Cited by 569
Cubic lipid-water phases: structures and biomembrane aspects
Larsson, K. (1989) · The Journal of Physical Chemistry · doi:10.1021/j100358a010 · Cited by 561
Alexandridis, P., Olsson, U., & Lindman, B. (1998) · Langmuir · doi:10.1021/la971117c · Cited by 538
Lipid‐based nanoparticles for contrast‐enhanced MRI and molecular imaging
Mulder, W. J. M., Strijkers, G. J., van Tilborg, G. A. F., Griffioen, A. W., & Nicolay, K. (2006) · NMR in Biomedicine · doi:10.1002/nbm.1011 · Cited by 535
Ionic liquids as amphiphile self-assembly media
Greaves, T. L., & Drummond, C. J. (2008) · Chemical Society Reviews · doi:10.1039/b801395k · Cited by 532
Self-citationSurfactant self-assembly objects as novel drug delivery vehicles
Drummond, C. J., & Fong, C. (1999) · Current Opinion in Colloid & Interface Science · doi:10.1016/s1359-0294(00)00020-0 · Cited by 515
Self-citationLeikin, S., Parsegian, V. A., Rau, D. C., & Rand, R. P. (1993) · Annual Review of Physical Chemistry · doi:10.1146/annurev.pc.44.100193.002101 · Cited by 488
Cubic phases of lipid-containing systems
Mariani, P., Luzzati, V., & Delacroix, H. (1988) · Journal of Molecular Biology · doi:10.1016/0022-2836(88)90607-9 · Cited by 481
Kulkarni, C. V., Wachter, W., Iglesias-Salto, G., Engelskirchen, S., & Ahualli, S. (2011) · Phys. Chem. Chem. Phys. · doi:10.1039/c0cp01539c · Cited by 448
Hyde, S. T., Andersson, S., Ericsson, B., & Larsson, K. (1984) · Zeitschrift für Kristallographie · doi:10.1524/zkri.1984.168.1-4.213 · Cited by 430
Modeling Water, the Hydrophobic Effect, and Ion Solvation
Dill, K. A., Truskett, T. M., Vlachy, V., & Hribar-Lee, B. (2005) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.34.040204.144517 · Cited by 401
Surfactant systems: their use in drug delivery
Lawrence, M. J. (1994) · Chemical Society Reviews · doi:10.1039/cs9942300417 · Cited by 401
Characterization and potential applications of nanostructured aqueous dispersions
Yaghmur, A., & Glatter, O. (2009) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2008.07.007 · Cited by 373
Aime, S., Castelli, D. D., Crich, S. G., Gianolio, E., & Terreno, E. (2009) · Accounts of Chemical Research · doi:10.1021/ar800192p · Cited by 350
Membrane protein crystallization
Caffrey, M. (2003) · Journal of Structural Biology · doi:10.1016/s1047-8477(03)00043-1 · Cited by 340
Angelova, A., Angelov, B., Mutafchieva, R., Lesieur, S., & Couvreur, P. (2011) · Accounts of Chemical Research · doi:10.1021/ar100120v · Cited by 337
Boyd, B. J., Whittaker, D. V., Khoo, S.-M., & Davey, G. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2005.11.033 · Cited by 333
Holmberg, K. (2001) · Current Opinion in Colloid & Interface Science · doi:10.1016/s1359-0294(01)00074-7 · Cited by 331
Squalenoyl Nanomedicines as Potential Therapeutics
Couvreur, P., Stella, B., Reddy, L. H., Hillaireau, H., Dubernet, C., Desmaële, D., Lepêtre-Mouelhi, S., Rocco, F., Dereuddre-Bosquet, N., Clayette, P., et al. (2006) · Nano Letters · doi:10.1021/nl061942q · Cited by 329
Self-Assembled Lipid Superstructures: Beyond Vesicles and Liposomes
Barauskas, J., Johnsson, M., & Tiberg, F. (2005) · Nano Letters · doi:10.1021/nl050678i · Cited by 312
Malmsten, M. (2006) · Soft Matter · doi:10.1039/b608348j · Cited by 304
Rand, R. P., Fuller, N. L., Gruner, S. M., & Parsegian, V. A. (1990) · Biochemistry · doi:10.1021/bi00453a010 · Cited by 300
Briggs, J., Chung, H., & Caffrey, M. (1996) · Journal de Physique II · doi:10.1051/jp2:1996208 · Cited by 287
Ordered 2-D and 3-D nanostructured amphiphile self-assembly materials stable in excess solvent
Kaasgaard, T., & Drummond, C. J. (2006) · Physical Chemistry Chemical Physics · doi:10.1039/b609510k · Cited by 268
Self-citationCharacterisation of drug release from cubosomes using the pressure ultrafiltration method
Boyd, B. (2003) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(03)00262-x · Cited by 245
Robust QSAR Models Using Bayesian Regularized Neural Networks
Burden, F. R., & Winkler, D. A. (1999) · Journal of Medicinal Chemistry · doi:10.1021/jm980697n · Cited by 241
Cubic membranes: a legend beyond the Flatland* of cell membrane organization
Almsherqi, Z. A., Kohlwein, S. D., & Deng, Y. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200603055 · Cited by 238
Haines, T. H. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.1.160 · Cited by 236
Structural and functional properties of hydration and confined water in membrane interfaces
Disalvo, E. A., Lairion, F., Martini, F., Tymczyszyn, E., Frías, M., Almaleck, H., & Gordillo, G. J. (2008) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2008.08.025 · Cited by 226
Cubic phases of self-assembled amphiphilic aggregates
Seddon, J. M., & Templer, R. H. (1993) · Philosophical Transactions of the Royal Society of London Series A Physical and Engineering Sciences · doi:10.1098/rsta.1993.0096 · Cited by 220
Crystallizing Membrane Proteins for Structure Determination: Use of Lipidic Mesophases
Caffrey, M. (2009) · Annual Review of Biophysics · doi:10.1146/annurev.biophys.050708.133655 · Cited by 211
Chong, J. Y. T., Mulet, X., Waddington, L. J., Boyd, B. J., & Drummond, C. J. (2011) · Soft Matter · doi:10.1039/c1sm05181d · Cited by 210
Self-citationZayed, J. M., Nouvel, N., Rauwald, U., & Scherman, O. A. (2010) · Chemical Society Reviews · doi:10.1039/b922348g · Cited by 181
Membrane Protein Crystallization In Meso: Lipid Type-Tailoring of the Cubic Phase
Cherezov, V., Clogston, J., Misquitta, Y., Abdel-Gawad, W., & Caffrey, M. (2002) · Biophysical Journal · doi:10.1016/s0006-3495(02)75339-3 · Cited by 179
BOYD, B., KHOO, S., WHITTAKER, D., DAVEY, G., & PORTER, C. (2007) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2007.03.020 · Cited by 169
Norling, T., Lading, P., Engström, S., Larsson, K., Krog, N., & Nissen, S. S. (1992) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.1992.tb02529.x · Cited by 166
Smith, R., & Tanford, C. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.2.289 · Cited by 163
Inverse micellar phases of phospholipids and glycolipids
Seddon, J. M., Robins, J., Gulik-Krzywicki, T., & Delacroix, H. (2000) · Physical Chemistry Chemical Physics · doi:10.1039/b004916f · Cited by 162
Greaves, T. L., Weerawardena, A., Fong, C., & Drummond, C. J. (2006) · Langmuir · doi:10.1021/la062895k · Cited by 155
Self-citationSelf-organization of amphiphiles
Evans, D. F. (1988) · Langmuir · doi:10.1021/la00079a002 · Cited by 144
Drug delivery to tumours: recent strategies
Reddy, L. H. (2005) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.57.10.0001 · Cited by 141
Hexosomes formed from glycerate surfactants—Formulation as a colloidal carrier for irinotecan
Boyd, B. J., Whittaker, D. V., Khoo, S., & Davey, G. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.03.010 · Cited by 137
Shinoda, W., Mikami, M., Baba, T., & Hato, M. (2004) · The Journal of Physical Chemistry B · doi:10.1021/jp035998+ · Cited by 123
McIntosh, T. J. (1996) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(96)02577-7 · Cited by 123
Kirk, G. L., & Gruner, S. M. (1985) · Journal de physique · doi:10.1051/jphys:01985004605076100 · Cited by 123
Conn, C. E., Ces, O., Mulet, X., Finet, S., Winter, R., Seddon, J. M., & Templer, R. H. (2006) · Physical Review Letters · doi:10.1103/physrevlett.96.108102 · Cited by 119
Gløgård, C., Stensrud, G., Hovland, R., Fossheim, S. L., & Klaveness, J. (2002) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(01)00935-8 · Cited by 101
Reddy, L. H., Khoury, H., Paci, A., Deroussent, A., Ferreira, H. J., Dubernet, C., Declèves, X., Besnard, M., Chacun, H., Lepêtre‐Mouelhi, S., et al. (2008) · Drug Metabolism and Disposition · doi:10.1124/dmd.108.020735 · Cited by 97
Edwards, K., Silvander, M., & Karlsson, G. (1995) · Langmuir · doi:10.1021/la00007a020 · Cited by 94
Yamauchi, K., Doi, K., Yoshida, Y., & Kinoshita, M. (1993) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(93)90353-2 · Cited by 94
Rand, R. P. (1992) · Science · doi:10.1126/science.256.5057.618 · Cited by 90
Membrane Protein Crystallization in Lipidic Mesophases with Tailored Bilayers
Misquitta, L. V., Misquitta, Y., Cherezov, V., Slattery, O., Mohan, J. M., Hart, D. J., Zhalnina, M. V., Cramer, W. A., & Caffrey, M. (2004) · Structure · doi:10.1016/j.str.2004.09.020 · Cited by 89
Boyd, B. J., Dong, Y., & Rades, T. (2009) · Journal of Liposome Research · doi:10.1080/08982100802691983 · Cited by 87
Quantifying Packing Frustration Energy in Inverse Lyotropic Mesophases
Duesing, P. M., Templer, R. H., & Seddon, J. M. (1997) · Langmuir · doi:10.1021/la960602p · Cited by 84
Sagnella, S. M., Gong, X., Moghaddam, M. J., Conn, C. E., Kimpton, K., Waddington, L. J., Krodkiewska, I., & Drummond, C. J. (2010) · Nanoscale · doi:10.1039/c0nr00781a · Cited by 84
Self-citationJohnsson, M., Barauskas, J., Norlin, A., & Tiberg, F. (2006) · Journal of Nanoscience and Nanotechnology · doi:10.1166/jnn.2006.402 · Cited by 80
Mulet, X., Gong, X., Waddington, L. J., & Drummond, C. J. (2009) · ACS Nano · doi:10.1021/nn900671u · Cited by 76
Self-citationReddy, L. H., Renoir, J., Marsaud, V., Lepêtre‐Mouelhi, S., Desmaële, D., & Couvreur, P. (2009) · Molecular Pharmaceutics · doi:10.1021/mp900099e · Cited by 74
Shalaev, E., & Steponkus, P. L. (1999) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(99)00068-1 · Cited by 74
Dynamic control of nanofluidic channels in protein drug delivery vehicles
Angelova, A., Angelov, B., Lesieur, S., Mutafchieva, R., Ollivon, M., Bourgaux, C., Willumeit‐Römer, R., & Couvreur, P. (2008) · Journal of Drug Delivery Science and Technology · doi:10.1016/s1773-2247(08)50005-0 · Cited by 68
An Optimal Self‐Pruning Neural Network and Nonlinear Descriptor Selection in QSAR
Burden, F. R., & Winkler, D. A. (2009) · QSAR & Combinatorial Science · doi:10.1002/qsar.200810202 · Cited by 65
Shinoda, W., Mikami, M., Baba, T., & Hato, M. (2003) · The Journal of Physical Chemistry B · doi:10.1021/jp035493j · Cited by 64
Rowiński, P., Bilewicz, R., Stébé, M., & Rogalska, E. (2003) · Analytical Chemistry · doi:10.1021/ac034612o · Cited by 64
Robust QSAR Models from Novel Descriptors and Bayesian Regularised Neural Networks
Winkler, D. A., & Burden, F. R. (2000) · Molecular Simulation · doi:10.1080/08927020008022374 · Cited by 61
Briggs, J., & Caffrey, M. (1994) · Biophysical Journal · doi:10.1016/s0006-3495(94)80632-0 · Cited by 61
Driever, C. D., Mulet, X., Johnston, A. P. R., Waddington, L. J., Thissen, H. W., Caruso, F., & Drummond, C. J. (2011) · Soft Matter · doi:10.1039/c0sm01410a · Cited by 55
Self-citationAkhter, M. S., & Alawi, S. M. (2003) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/s0927-7757(03)00055-4 · Cited by 53
Gong, X., Moghaddam, M. J., Sagnella, S. M., Conn, C. E., Danon, S. J., Waddington, L. J., & Drummond, C. J. (2011) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2011.03.007 · Cited by 42
Self-citationGong, X., Moghaddam, M. J., Sagnella, S. M., Conn, C. E., Danon, S. J., Waddington, L. J., & Drummond, C. J. (2011) · ACS Applied Materials & Interfaces · doi:10.1021/am200117u · Cited by 41
Self-citationBiocatalysis in reverse self-assembling structures: Reverse micelles and reverse vesicles
Sánchez‐Ferrer, Á., & García‐Carmona, F. (1994) · Enzyme and Microbial Technology · doi:10.1016/0141-0229(94)90156-2 · Cited by 41
Sagnella, S. M., Conn, C. E., Krodkiewska, I., Moghaddam, M. J., Seddon, J. M., & Drummond, C. J. (2009) · Langmuir · doi:10.1021/la903005q · Cited by 40
Self-citationConn, C. E., Panchagnula, V., Weerawardena, A., Waddington, L. J., Kennedy, D. F., & Drummond, C. J. (2009) · Langmuir · doi:10.1021/la904006q · Cited by 40
Self-citationMannock, D. A., & McElhaney, R. N. (2004) · Current Opinion in Colloid & Interface Science · doi:10.1016/j.cocis.2004.01.009 · Cited by 39
Polymeric Drugs and Drug Delivery Systems
Kennedy, J. F., & Pagliuca, G. (1992) · Carbohydrate Polymers · doi:10.1016/0144-8617(92)90098-b · Cited by 35
Shearman, G. C., Ces, O., & Templer, R. H. (2009) · Soft Matter · doi:10.1039/b911699k · Cited by 29
Sagnella, S. M., Conn, C. E., Krodkiewska, I., Moghaddam, M. J., & Drummond, C. J. (2010) · The Journal of Physical Chemistry B · doi:10.1021/jp910578h · Cited by 22
Self-citationGong, X., Moghaddam, M. J., Sagnella, S. M., Conn, C. E., Mulet, X., Danon, S. J., Waddington, L. J., & Drummond, C. J. (2011) · Soft Matter · doi:10.1039/c1sm05330b · Cited by 22
Self-citationKent, B., Garvey, C. J., Cookson, D., & Bryant, G. (2008) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2008.10.003 · Cited by 19
Pohle, W., Selle, C., Gauger, D. R., & Brandenburg, K. (2001) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2001.10506745 · Cited by 12
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Metadata
- Authors
- Fong, C., Le, T., & Drummond, C. J.
- Venue
- Chem. Soc. Rev.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2012
- Volume
- 41
- Issue
- 3
- Pages
- 1297-1322
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W1972557235
- Cited by
- 338
- References
- 96
- FWCI
- 0.52
- Type
- journal article
- Language
- en
- Open access
- green
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