The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
UV- and NIR-responsive polymeric nanomedicines for on-demand drug delivery
Abstract
Ultraviolet (UV) and near infrared (NIR) light-responsive polymeric nanomedicines (e.g., cargo-loaded micelles and vesicles) have increasingly received much attention for their applications in the spatiotemporal and on-demand drug delivery and disease therapy. This UV/NIR-sensitivity is activated via a one-photon and/or two-photon absorption process. The phototriggered micellar disruption and drug release have three mechanisms: (1) the hydrophobicity–hydrophilicity transition, (2) the photocleavage reaction, and (3) the cascade depolymerization reaction (e.g., self-immolative polymers). As NIR light can penetrate deeply into tissues (up to several inches) with less damage and scattering compared with UV and visible light, the polymeric nanomedicines simultaneously exhibiting both UV- and NIR-sensitivity hold great potential in clinical medicine and are especially discussed in this review.
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Cites
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Cited by
Photoresponsive nanoparticles for drug delivery
Rwei, A. Y., Wang, W., & Kohane, D. S. (2015) · Nano Today · doi:10.1016/j.nantod.2015.06.004 · Cited by 318
Zwitterionic light-responsive polymeric micelles for controlled drug delivery
Shen, H., Zhou, M., Zhang, Q., Keller, A., & Shen, Y. (2015) · Colloid and Polymer Science · doi:10.1007/s00396-015-3550-7 · Cited by 36
Mussel-inspired hydrogel composite with multi-stimuli responsive behavior
Yan, Y., Rong, L., Ge, J., Tiu, B. D. B., Cao, P., & Advincula, R. C. (2019) · Macromolecular Materials and Engineering · doi:10.1002/mame.201800720 · Cited by 18
Metadata
- Authors
- Liu, G., Liu, W., & Dong, C.-M.
- Venue
- Polymer Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2013
- Volume
- 4
- Issue
- 12
- Pages
- 3431
- ISSN
- 1759-9954 (ISSN-L)
- 1759-9962
- OpenAlex
- W2101939655
- Cited by
- 195
- References
- 10
- FWCI
- 9.22
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.