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Cited by 195

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

UV- and NIR-responsive polymeric nanomedicines for on-demand drug delivery

Liu, Gang, Liu, Wei, Dong, Chang-Ming·2013·Polymer Chemistry

Abstract

Ultraviolet (UV) and near infrared (NIR) light-responsive polymeric nanomedicines (e.g., cargo-loaded micelles and vesicles) have increasingly received much attention for their applications in the spatiotemporal and on-demand drug delivery and disease therapy. This UV/NIR-sensitivity is activated via a one-photon and/or two-photon absorption process. The phototriggered micellar disruption and drug release have three mechanisms: (1) the hydrophobicity–hydrophilicity transition, (2) the photocleavage reaction, and (3) the cascade depolymerization reaction (e.g., self-immolative polymers). As NIR light can penetrate deeply into tissues (up to several inches) with less damage and scattering compared with UV and visible light, the polymeric nanomedicines simultaneously exhibiting both UV- and NIR-sensitivity hold great potential in clinical medicine and are especially discussed in this review.

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Metadata

Authors
Liu, G., Liu, W., & Dong, C.-M.
Venue
Polymer Chemistry
Published
2013
Volume
4
Issue
12
Pages
3431
ISSN
  • 1759-9954 (ISSN-L)
  • 1759-9962
OpenAlex
W2101939655
Cited by
195
References
10
FWCI
9.22
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: UV- and NIR-responsive polymeric nanomedicines for on-demand drug delivery. https://app.cochat.ai/papers/10.1039/c3py21121e
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Liu, G., Liu, W., & Dong, C.-M. (2013). UV- and NIR-responsive polymeric nanomedicines for on-demand drug delivery. Polymer Chemistry. https://doi.org/10.1039/c3py21121e

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