The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
In depth analysis of the in vivo toxicity of nanoparticles of porous iron(iii) metal–organic frameworks
Abstract
In vivo acute toxicity of high doses of nanoparticles of three different porous iron(III) carboxylate Metal–Organic Frameworks (nanoMOFs) was intravenously investigated in rats by evaluating their distribution, metabolism and excretion. All studied parameters (serum, enzymatic, histological, etc.) are in agreement with a low acute toxicity. The mechanism of degradation and excretion of the nanoMOFs has been evidenced and shows that the nanoparticles are rapidly sequestered by the liver and spleen, then further biodegraded and directly eliminated in urine or feces without metabolization and substantial toxicity.
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Cites
LXXIII.—Oxidation of tartaric acid in presence of iron
Fenton, H. J. H. (1894) · J. Chem. Soc., Trans. · doi:10.1039/ct8946500899 · Cited by 3,179
Sharifi, S., Behzadi, S., Laurent, S., Laird Forrest, M., Stroeve, P., & Mahmoudi, M. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15188f · Cited by 1,460
NO-Releasing Zeolites and Their Antithrombotic Properties
Wheatley, P. S., Butler, A. R., Crane, M. S., Fox, S., Xiao, B., Rossi, A. G., Megson, I. L., & Morris, R. E. (2006) · Journal of the American Chemical Society · doi:10.1021/ja0503579 · Cited by 235
Cited by
Metal-organic frameworks for advanced drug delivery
He, S., Wu, L., Li, X., Sun, H., Xiong, T., Liu, J., Huang, C., Xu, H., Sun, H., Chen, W., et al. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.03.019 · Cited by 528
Self-citationMetal-organic frameworks: structure, properties, methods of synthesis and characterization
Butova, V. V., Soldatov, M. A., Guda, A. A., Lomachenko, K. A., & Lamberti, C. (2016) · Russian Chemical Reviews · doi:10.1070/rcr4554 · Cited by 527
Toxicity of metal–organic framework nanoparticles: from essential analyses to potential applications
Ettlinger, R., Lächelt, U., Gref, R., Horcajada, P., Lammers, T., Serre, C., Couvreur, P., Morris, R. E., & Wuttke, S. (2022) · Chemical Society Reviews · doi:10.1039/d1cs00918d · Cited by 423
Self-citationMin, H., Wang, J., Qi, Y., Zhang, Y., Han, X., Xu, Y., Xu, J., Li, Y., Chen, L., Cheng, K., et al. (2019) · Advanced Materials · doi:10.1002/adma.201808200 · Cited by 394
Cai, W., Gao, H., Chu, C., Wang, X., Wang, J., Zhang, P., Lin, G., Li, W., Liu, G., & Chen, X. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b11579 · Cited by 357
Metadata
- Authors
- Baati, T., Njim, L., Neffati, F., Kerkeni, A., Bouttemi, M., Gref, R., Najjar, M. F., Zakhama, A., Couvreur, P., Serre, C., & Horcajada, P.
- Venue
- Chemical Science
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2013
- Volume
- 4
- Issue
- 4
- Pages
- 1597
- ISSN
- 2041-6520 (ISSN-L)
- 2041-6539
- OpenAlex
- W2135465393
- Cited by
- 405
- References
- 3
- FWCI
- 9.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- Baati, T., Njim, L., Neffati, F., Kerkeni, A., Bouttemi, M., Gref, R., Najjar, M. F., Zakhama, A., Couvreur, P., Serre, C., & Horcajada, P. (2013). In depth analysis of the in vivo toxicity of nanoparticles of porous iron(iii) metal–organic frameworks. Chemical Science. https://doi.org/10.1039/c3sc22116d
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